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1. 发明申请

WO2013130613A1 ECTOPARASITE DETECTION 审中-公开
标题翻译： ECTOPARASITE检测
公开(公告)号：WO2013130613A1
公开(公告)日：2013-09-06
申请号：PCT/US2013/028028
申请日：2013-02-27
申请人： SRI INTERNATIONAL
发明人： VAIDYANATHAN, Rajeev , PERRONE, Joseph , BEAULIEU, Ellen , FIELDS, Scott
IPC分类号： C12Q1/04 , G01N33/563 , G01N33/569
CPC分类号： G01N33/5308 , C07K16/18 , G01N2333/43552 , G01N2333/43556 , G01N2333/43582 , G01N2333/43586
摘要： Ectoparasite infestation of a substrate like bedding is detected by contacting a sample from the substrate with a polyclonal ectoparasite antibody generated from a whole ectoparasite immunogen, under conditions wherein the antibody specifically binds ectoparasite antigen in the sample.
摘要翻译：通过使来自底物的样品与由整个外寄生物免疫原产生的多克隆外寄生物抗体在其中特异性结合样品中的外寄生物抗原的条件下接触来检测底物类似床上的外寄生物侵袭。

2. 发明申请

WO2012052719A1 DETECTION AND/OR DIAGNOSIS OF MITE INFECTIONS IN SHEEP 审中-公开
标题翻译：蛭石感染的检测和/或诊断
公开(公告)号：WO2012052719A1
公开(公告)日：2012-04-26
申请号：PCT/GB2011/001506
申请日：2011-10-19
申请人： MOREDUN RESEARCH INSTITUTE , NISBET, Alasdair, Justice , HUNTLEY, John, Frederick , BURGESS, Stewart, Thomas, George
发明人： NISBET, Alasdair, Justice , HUNTLEY, John, Frederick , BURGESS, Stewart, Thomas, George
IPC分类号： G01N33/50 , G01N33/53
CPC分类号： G01N33/5308 , G01N2333/43582 , G01N2469/20
摘要： This invention provides a mite group 2 allergen for use in detecting P. ovis and/or for diagnosing, detecting or evaluating diseases and/or conditions caused or contributed to by P. ovis.
摘要翻译：本发明提供了一种用于检测肺炎支原体的螨组2变应原和/或用于诊断，检测或评估由P. ovis引起或促成的疾病和/或病症的螨2变应原。

3. 发明申请

WO2019089719A1 TEST STRIP TO IDENTIFY INSECT & ARACHNID ECTOPARASITES 审中-公开
公开(公告)号：WO2019089719A1
公开(公告)日：2019-05-09
申请号：PCT/US2018/058398
申请日：2018-10-31
申请人： GOLD, Robert, S. , PARASITE ID, LLC
发明人： GOLD, Robert, S.
IPC分类号： G01N33/53 , G01N33/538 , G01N33/558
CPC分类号： G01N33/5308 , G01N33/558 , G01N2333/43582
摘要： The a test strip is provided for detecting the presence of insect and/or arachnid ectoparasites and/or their eggs.

4. 发明申请

WO2002076477A1 SKIN-TEST REAGENTS AND SERUM SPECIFIC IGE, IGG SUBTYPES DETECTION KITS, COMPRISING CRUDE EXTRACTS OF SPIDER MITES SUCH AS CITRUS RED MITE, TWO-SPOTTED SPIDER MITE AND EUROPEAN RED MITE 审中-公开
标题翻译：皮肤试验试剂和血清特异性，IGG亚型检测试剂盒，包括天ER ING ING M ING ING US M M M M ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE ITE
公开(公告)号：WO2002076477A1
公开(公告)日：2002-10-03
申请号：PCT/KR2002/000534
申请日：2002-03-27
申请人： BIOALLETECH CO., LTD. , KIM, You-Young , MIN, Kyung-Up , PARK, Hae-Sim , CHO, Sang-Heon , KIM, Yoon-Keun
发明人： KIM, You-Young , MIN, Kyung-Up , PARK, Hae-Sim , CHO, Sang-Heon , KIM, Yoon-Keun
IPC分类号： A61K35/64
CPC分类号： G01N33/6854 , G01N2333/43582
摘要： Disclosed are skin test reagents and serum-specific IgE and IgG subtype detection kits comprising crude extracts of spider mites that which can diagnose specific allergic diseases caused by spider mites (Citrus Red Mite, Two-Spotted Mite, European Red Mite).
摘要翻译：公开了皮肤试验试剂和血清特异性IgE和IgG亚型检测试剂盒，其包括可以诊断由蜘蛛螨（Citrus Red Mite，Two-Spotted Mite，European Red Mite）引起的特异性过敏性疾病的蜘蛛螨粗提取物。

5. 发明申请

WO01011365A1 METHOD FOR DETECTION OF MITE INFECTION 审中-公开
标题翻译：检测螨感染的方法
公开(公告)号：WO01011365A1
公开(公告)日：2001-02-15
申请号：PCT/AU2000/000930
申请日：2000-08-04
IPC分类号： G01N33/53 , G01N33/573 , G01N33/564 , G01N33/577 , G01N33/68
CPC分类号： G01N33/573 , G01N33/5308 , G01N2333/43582 , G01N2333/924 , G01N2333/976
摘要： The present invention provides methods or diagnostic assays for the detection of mite infections in animals and humans, in particular, the detection of the scabies mite, Sarcoptes scabiei . The methods involve contacting a sample form the animal with antibodies to: (a) mite alpha-amylase or other antigen in contact with the immune system of the animal early in the infection; and/or (b) transferring or other auto-antigen induced by the infection. Alternatively, the methods involve contacting a sample from the animal with mite alpha-amylase or other antigen in contact with the immune system of the animal early in the infection to indicate the presence in the sample of antibodies to the mite alpha-amylase or said other antigen. The invention also provides diagnostic test kits for carrying out those assays and to agents used in those assays, including diagnostic reagents and antibodies.
摘要翻译：本发明提供用于检测动物和人类中的螨感染的方法或诊断测定法，特别是sc疮螨Sarcoptes scabiei的检测。所述方法包括将来自动物的样品与抗体接触：（a）在感染早期与动物的免疫系统接触的螨α-淀粉酶或其它抗原; 和/或（b）由感染诱导的转移或其他自身抗原。或者，所述方法包括使来自动物的样品与感染早期与动物的免疫系统接触的螨α-淀粉酶或其它抗原接触，以指示在样品中存在螨α-淀粉酶或所述其他抗体的抗体抗原。本发明还提供了用于进行这些测定的诊断测试试剂盒和用于那些测定中的试剂，包括诊断试剂和抗体。

6. 发明申请

WO00050450A1 MITE PROTEIN 审中-公开
标题翻译： MITE蛋白
公开(公告)号：WO00050450A1
公开(公告)日：2000-08-31
申请号：PCT/SE2000/000346
申请日：2000-02-22
IPC分类号： A61K38/00 , C07K14/435 , C07K16/18 , G01N33/68 , C07K16/00 , G01N33/569 , A61K39/00
CPC分类号： C07K14/43531 , A61K38/00 , C07K16/18 , G01N33/6893 , G01N2333/43582 , G01N2800/20
摘要： The present invention relates to a novel major mite antigen, which according to the invention has been isolated and sequenced for the first time. More specifically, said antigen is a protein originating from the mite Sarcoptes scabiei. Thus, the invention relates to said antigen as well as to the encoding nucleic acid as defined in the claims. Further, the invention also relates to advantageous uses of the novel protein and/or functional fragments thereof, e.g. in immunological testing, such as in ELISA methods, as well as in the preparation of vaccines.
摘要翻译：本发明涉及一种新的主要螨抗原，其根据本发明已被首次分离和测序。更具体地说，所述抗原是起源于螨虫痂病的蛋白质。因此，本发明涉及所述抗原以及权利要求中定义的编码核酸。此外，本发明还涉及新型蛋白质和/或其功能片段的有利用途，例如，在免疫测试中，例如在ELISA方法中以及在疫苗的制备中。

7. 发明申请

WO2010132097A2 COMPOSITIONS AND METHODS FOR PEST CONTROL 审中-公开
标题翻译：用于病虫害防治的组合物和方法
公开(公告)号：WO2010132097A2
公开(公告)日：2010-11-18
申请号：PCT/US2010/001382
申请日：2010-05-11
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , NORTHEASTERN UNIVERSITY , BACHELET, Ido , SASISEKHARAN, Ram , BULMER, Mark , ROSENGAUS, Rebeca, B.
发明人： BACHELET, Ido , SASISEKHARAN, Ram , BULMER, Mark , ROSENGAUS, Rebeca, B.
IPC分类号： A01N43/16 , C08B37/00 , B32B1/02 , G01N33/53 , C12Q1/34 , A01P7/04
CPC分类号： C12Q1/34 , A01N43/16 , C08B37/0024 , G01N2333/43552 , G01N2333/43582 , G01N2333/924 , Y10T428/13 , A01N25/34
摘要： Provided herein are compositions and kits comprising carbohydrate-based inhibitors that bind GNBP and/or inhibit β(l,3)-glucanase activity. Also provided are methods of using such inhibitors to protect against or treat pest infestation, as are compositions and kits comprising subparts of the carbohydrate-based inhibitors.
摘要翻译：本文提供了包含结合GNBP和/或抑制β（1,3） - 葡聚糖酶活性的基于碳水化合物的抑制剂的组合物和试剂盒。还提供了使用这种抑制剂来防止或治疗害虫侵袭的方法，组合物和试剂盒包括基于碳水化合物的抑制剂的子部分。

8. 发明申请

WO2003016529A1 NOVEL BLOMIA TROPICALIS ANTIGENS AND USES THEREFOR 审中-公开
标题翻译：新型BLOMIA TROPICALIS抗生素及其用途
公开(公告)号：WO2003016529A1
公开(公告)日：2003-02-27
申请号：PCT/AU2002/001125
申请日：2002-08-20
申请人： CHUA, Kaw, Yan , CHEONG, Nge , LEE, Bee, Wah
发明人： CHUA, Kaw, Yan , CHEONG, Nge , LEE, Bee, Wah
IPC分类号： C12N15/12
CPC分类号： C07K14/43531 , A61K39/00 , C07K16/18 , G01N33/5308 , G01N2333/43582 , G01N2469/20
摘要： The present invention relates generally to a novel protein molecule and to derivatives, homologs, analogs, chemical equivalents and mimetics thereof capable of inducing, upregulating or otherwise facilitating the induction of an immune response to a mite and, more particularly, a mite from the family Glycyphagidae . These mites include dust mites and storage mites. The present invention also contemplates a genetic sequence encoding said protein molecule and derivatives, homologs, analogs, chemical equivalents and mimetics thereof. The present invention further provides genetic vaccines and other compositions comprising nucleic acid molecules. The protein molecule of the present invention may be regarded as a protein allergen and used alone or in combination with known allergens provides the possibility for developing more comprehensive tests for potential allergic responses. The protein allergen or its encoding sequence of the present invention are also useful, inter alia , in a range of therapeutic, prophylactic and diagnostic applications.
摘要翻译：本发明一般涉及一种新型蛋白质分子及其衍生物，同系物，类似物，化学等价物和其模拟物，其能够诱导，上调或以其它方式促进对螨的免疫应答的诱导，更特别地，来自家族的螨 id科这些螨虫包括尘螨和储存螨虫。本发明还考虑了编码所述蛋白质分子及其衍生物，同系物，类似物，化学等价物和其模拟物的遗传序列。本发明还提供了包含核酸分子的基因疫苗和其它组合物。本发明的蛋白质分子可被认为是蛋白质变应原，并且单独使用或与已知的变应原组合使用，提供了对潜在的过敏反应进行更全面的测试的可能性。本发明的蛋白质过敏原或其编码序列尤其可用于一系列治疗，预防和诊断应用。

9. 发明申请

WO2010132097A3 COMPOSITIONS AND METHODS FOR PEST CONTROL 审中-公开
标题翻译：用于病虫害防治的组合物和方法
公开(公告)号：WO2010132097A3
公开(公告)日：2011-09-22
申请号：PCT/US2010001382
申请日：2010-05-11
申请人： MASSACHUSETTS INST TECHNOLOGY , UNIV NORTHEASTERN , BACHELET IDO , SASISEKHARAN RAM , BULMER MARK , ROSENGAUS REBECA B
发明人： BACHELET IDO , SASISEKHARAN RAM , BULMER MARK , ROSENGAUS REBECA B
IPC分类号： A01N43/16 , A01N43/90
CPC分类号： C12Q1/34 , A01N43/16 , C08B37/0024 , G01N2333/43552 , G01N2333/43582 , G01N2333/924 , Y10T428/13 , A01N25/34
摘要： Provided herein are compositions and kits comprising carbohydrate-based inhibitors that bind GNBP and/or inhibit ß(l,3)-glucanase activity. Also provided are methods of using such inhibitors to protect against or treat pest infestation, as are compositions and kits comprising subparts of the carbohydrate-based inhibitors.
摘要翻译：本文提供了包含结合GNBP和/或抑制β（1,3） - 葡聚糖酶活性的基于碳水化合物的抑制剂的组合物和试剂盒。还提供了使用这种抑制剂来防止或治疗害虫侵袭的方法，组合物和试剂盒包括基于碳水化合物的抑制剂的子部分。

10. 发明申请

WO2007124524A1 HOUSE DUST MITE ALLERGEN 审中-公开
公开(公告)号：WO2007124524A1
公开(公告)日：2007-11-08
申请号：PCT/AT2007/000201
申请日：2007-04-27
申请人： BIOMAY AG , VALENTA, Rudolf , WEGHOFER, Margit , VRTALA, Susanne , HORAK, Friedrich , VALENT, Peter , FLORIAN, Stefan
发明人： VALENTA, Rudolf , WEGHOFER, Margit , VRTALA, Susanne , HORAK, Friedrich , VALENT, Peter , FLORIAN, Stefan
IPC分类号： C07K14/435
CPC分类号： C07K14/43531 , A61K39/35 , A61K2039/505 , A61K2039/55566 , C07K7/06 , C07K7/08 , C07K16/18 , C07K17/08 , C07K2317/76 , G01N33/6854 , G01N33/6893 , G01N2333/43582 , G01N2800/24
摘要： A polypeptide comprising an amino acid sequence having at least 60 % identity to the amino acid sequence SEQ ID No. 1 or comprising at least one amino acid fragment of at least 6 consecutive amino acid residues of the amino acid sequence SEQ ID No. 1 or having immunological cross-reactivity to the amino acid sequence SEQ ID No. 1 or fragments thereof, wherein the amino acid sequence SEQ ID No. 1 codes for an allergen and the polypeptide comprises at least one T cell epitope recognized by a T cell receptor specific for a molecule having the amino acid sequence SEQ ID No. 1.
摘要翻译：一种多肽，其包含与氨基酸序列SEQ ID No.1具有至少60％同一性的氨基酸序列，或包含氨基酸序列SEQ ID No.1的至少6个连续氨基酸残基的至少一个氨基酸片段或对氨基酸序列SEQ ID No.1或其片段具有免疫学交叉反应性，其中氨基酸序列SEQ ID No.1编码变应原和多肽包含至少一个被T细胞受体特异性识别的T细胞表位对于具有氨基酸序列SEQ ID No.1的分子。

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