专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明申请

US20090176250A1 Immunoliposome-Nucleic Acid Amplification (ILNAA) Assay 失效
标题翻译：免疫脂质体 - 核酸扩增（ILNAA）测定
公开(公告)号：US20090176250A1
公开(公告)日：2009-07-09
申请号：US12399060
申请日：2009-03-06
申请人： Timothy J. O'Leary , Jeffrey T. Mason
发明人： Timothy J. O'Leary , Jeffrey T. Mason
IPC分类号： G01N33/53
CPC分类号： A61K9/127 , C12Q1/6806 , C12Q2563/161
摘要： Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.
摘要翻译：免疫脂质体及其在高度特异性和灵敏的核酸扩增测定中的应用，其依赖于在脂质体上的受体之后从脂质体中的包封释放的特异性核酸序列的扩增与固定在选择表面上的靶向分析物/抗原相结合。免疫脂质体核酸扩增测定允许定量和定性分析物检测。

62. 发明授权

US07527608B2 Medication infusion and aspiration system and method 失效
标题翻译：药物输液和抽吸系统及方法
公开(公告)号：US07527608B2
公开(公告)日：2009-05-05
申请号：US10909157
申请日：2004-07-30
申请人： Jeffrey T. Mason
发明人： Jeffrey T. Mason
IPC分类号： A61M1/00 , F04B39/00 , F04B53/00
CPC分类号： A61M1/0058 , A61M1/0011 , A61M1/0084 , A61M5/1413 , A61M5/14232 , A61M5/16831 , A61M2205/123 , A61M2205/18 , A61M2205/6045
摘要： A medication infusion system may include a controller and a reservoir module including a reservoir containing medication to be delivered to an internal wound site via the controller. The controller may have a peristaltic pump driven by a motor to urge medication to flow toward the internal wound site. The controller and the reservoir module may each have a mating surface oriented such that the reservoir module can slide into engagement with the controller along a direction parallel to an axis of rotation of the motor. The mating surfaces may have features such as dovetails that facilitate secure assembly and retention. A reservoir module may include only a single reservoir for infusion, or two separate reservoirs for infusion and aspiration. One single controller may be capable of mating with either type of reservoir module to provide only infusion, or infusion combined with aspiration, as desired.
摘要翻译：药物输注系统可以包括控制器和储存器模块，其包括含有经由控制器输送到内部伤口部位的药物的容器。控制器可以具有由马达驱动的蠕动泵，以促使药物流向内部伤口部位。控制器和储存器模块可以各自具有取向的配合表面，使得储存器模块可以沿着平行于电动机的旋转轴线的方向滑动与控制器接合。配合表面可以具有诸如燕尾形的特征，其有助于安全的组装和保持。储存器模块可以仅包括用于输注的单个储存器或用于输注和抽吸的两个单独的储存器。一个单一的控制器可能能够与任一种类型的贮存器模块相匹配，以根据需要仅提供输注或与抽吸结合的输液。

63. 发明授权

US07060045B2 Orthosis providing dynamic tracking of the patello-femoral joint 有权
标题翻译：矫形术提供髌股关节的动态跟踪
公开(公告)号：US07060045B2
公开(公告)日：2006-06-13
申请号：US10420344
申请日：2003-04-22
申请人： Jeffrey T. Mason , James M. Fout
发明人： Jeffrey T. Mason , James M. Fout
IPC分类号： A61F5/00
CPC分类号： A61F5/0125 , A61F2005/0176
摘要： A knee orthosis is provided having upper and lower arms and a hinge assembly positionable about the knee to one side of the patella. The hinge assembly has a hinge pivot and a tension strap lever. The upper and lower arms and tension strap lever are each rotatable about the hinge pivot. A compression member is positioned in engagement with the knee on the opposite side of the patella from the hinge assembly and a tension strap is connected to the compression member and the tension strap lever. The tension strap applies a tension force to the compression member which increases when the upper and lower arms and tension strap lever rotationally transition from a flexion position to an extension position and decreases when the upper and lower arms and tension strap lever rotationally transition from the extension position to the flexion position.
摘要翻译：提供了一种膝关节矫形器，其具有上臂和下臂以及可围绕膝盖定位到髌骨一侧的铰链组件。铰链组件具有铰链枢轴和张力带杆。上臂和下臂和张紧带杆各自可绕铰链枢轴转动。压缩构件定位成与髌骨的与铰链组件相反的一侧上的膝盖接合，并且张紧带连接到压缩构件和张紧带杆。张力带对压缩构件施加张力，当上臂和下臂和张紧带杆从弯曲位置旋转地转动到延伸位置时，压力构件增加，并且当上臂和下臂和张紧带杆从延伸部旋转地转动时，位置到屈曲位置。

64. 发明授权

US06260890B1 Tubing connector 失效
标题翻译：管接头
公开(公告)号：US06260890B1
公开(公告)日：2001-07-17
申请号：US09374703
申请日：1999-08-12
申请人： Jeffrey T. Mason
发明人： Jeffrey T. Mason
IPC分类号： F16L2500
CPC分类号： F16L33/224 , A61M39/1011 , F16L19/065
摘要： A tubing connector has a body, a tubular member, a compression member, a cap and a coupling. The body has a bore extending through it and a body portion of the tubular member is positioned in the bore of the body with an extension portion of the tubular member extending from the bore of the body. The compression member is fitted in the cap and also has a bore extending through it. The cap is provided with an opening and an orifice which are aligned with the bore of the compression member to define a continuous passageway through the cap. The coupling connectively engages the body with the cap. The tubing connector also optionally includes a coupling element which enables connective engagement of the body with an adjoining member. To use the tubing connector, the flexible tube is threaded through the continuous passageway of the cap and fitted over the extension portion of the tubular member. The cap and the body are then connectively engaged around the extension portion. The body applies a compressive force to the elastically-deformable compression member when engaged with the cap which retains the flexible tube in place while the non-elastically-deformable tubular member prevents the compressive force from collapsing the flexible tube.
摘要翻译：管连接器具有主体，管状构件，压缩构件，帽和联接器。主体具有延伸穿过其的孔，并且管状构件的主体部分定位在主体的孔中，其中管状构件的延伸部分从主体的孔延伸。压缩构件安装在盖中并且还具有延伸穿过其的孔。盖设置有与压缩构件的孔对准的开口和孔，以限定通过盖的连续通道。联轴器将主体与盖连接。管连接器还可选地包括联接元件，其能够使主体与相邻构件的连接接合。为了使用管连接器，柔性管穿过帽的连续通道并且装配在管状构件的延伸部分上。然后将盖和主体连接地接合在延伸部分周围。当与将弹性管保持在适当位置的盖接合时，本体对可弹性变形的压缩构件施加压缩力，而不可弹性变形的管状构件防止压缩力使柔性管塌陷。

65. 发明授权

US08481283B2 Pressure-assisted molecular recovery (PAMR) of biomolecules, pressure-assisted antigen retrieval (PAAR), and pressure-assisted tissue histology (PATH) 有权
标题翻译：生物分子的压力辅助分子回收（PAMR），压力辅助抗原回收（PAAR）和压力辅助组织组织学（PATH）
公开(公告)号：US08481283B2
公开(公告)日：2013-07-09
申请号：US13613618
申请日：2012-09-13
申请人： Timothy J. O'Leary , Jeffrey T. Mason , Carol B. Fowler , Robert E. Cunningham
发明人： Timothy J. O'Leary , Jeffrey T. Mason , Carol B. Fowler , Robert E. Cunningham
IPC分类号： G01N1/30
CPC分类号： A01N1/0231 , G01N1/30
摘要： A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
摘要翻译：公开了一种用于逆转已经保留用于组织学检查的组织标本中固定诱导交联的方法。该方法包括将固定组织置于液体中，该温度和压力条件足以逆转固定诱导的交联，恢复对蛋白质的抗原性，并允许改进保藏组织标本的分子和蛋白质组学分析。还公开了用于处理在升高的压力条件下进行组织学检查的组织的方法，其增强液体试剂灌注到组织中并减少总体加工时间。

66. 发明申请

US20130011854A1 PRESSURE-ASSISTED MOLECULAR RECOVERY (PAMR) OF BIOMOLECULES, PRESSURE-ASSISTED ANTIGEN RETRIEVAL (PAAR), AND PRESSURE-ASSISTED TISSUE HISTOLOGY (PATH) 有权
标题翻译：生物分子的压力辅助分子恢复（PAMR），压力辅助抗体检索（PAAR）和压力协助组织学（PATH）
公开(公告)号：US20130011854A1
公开(公告)日：2013-01-10
申请号：US13613618
申请日：2012-09-13
申请人： Timothy J. O'Leary , Jeffrey T. Mason , Carol B. Fowler , Robert E. Cunningham
发明人： Timothy J. O'Leary , Jeffrey T. Mason , Carol B. Fowler , Robert E. Cunningham
IPC分类号： G01N1/30
CPC分类号： A01N1/0231 , G01N1/30
摘要： A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
摘要翻译：公开了一种用于逆转已经保留用于组织学检查的组织标本中固定诱导交联的方法。该方法包括将固定组织置于液体中，该温度和压力条件足以逆转固定诱导的交联，恢复对蛋白质的抗原性，并允许改进保藏组织标本的分子和蛋白质组学分析。还公开了用于处理在升高的压力条件下进行组织学检查的组织的方法，其增强液体试剂灌注到组织中并减少总体加工时间。

67. 发明授权

US08288122B2 Pressure-assisted molecular recovery (PAMR) of biomolecules, pressure-assisted antigen retrieval (PAAR), and pressure-assisted tissue histology (PATH) 有权
标题翻译：生物分子的压力辅助分子回收（PAMR），压力辅助抗原回收（PAAR）和压力辅助组织组织学（PATH）
公开(公告)号：US08288122B2
公开(公告)日：2012-10-16
申请号：US12630746
申请日：2009-12-03
申请人： Timothy J. O'Leary , Jeffrey T. Mason , Carol B. Fowler , Robert E. Cunningham
发明人： Timothy J. O'Leary , Jeffrey T. Mason , Carol B. Fowler , Robert E. Cunningham
IPC分类号： G01N1/30
CPC分类号： A01N1/0231 , G01N1/30
摘要： A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
摘要翻译：公开了一种用于逆转已经保留用于组织学检查的组织标本中固定诱导交联的方法。该方法包括将固定组织置于液体中，该温度和压力条件足以逆转固定诱导的交联，恢复对蛋白质的抗原性，并允许改进保藏组织标本的分子和蛋白质组学分析。还公开了用于处理在升高的压力条件下进行组织学检查的组织的方法，其增强液体试剂灌注到组织中并减少总体加工时间。

68. 发明授权

US07662568B2 Immunoliposome-nucleic acid amplification (ILNAA) assay 失效
标题翻译：免疫脂质体 - 核酸扩增（ILNAA）检测
公开(公告)号：US07662568B2
公开(公告)日：2010-02-16
申请号：US12399060
申请日：2009-03-06
申请人： Timothy J. O'Leary , Jeffrey T. Mason
发明人： Timothy J. O'Leary , Jeffrey T. Mason
IPC分类号： C12Q1/68
CPC分类号： A61K9/127 , C12Q1/6806 , C12Q2563/161
摘要： Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.
摘要翻译：免疫脂质体及其在高度特异性和灵敏的核酸扩增测定中的应用，其依赖于在脂质体上的受体之后从包封在脂质体内释放的特异性核酸序列的扩增与固定在选择表面上的靶向分析物/抗原相结合。免疫脂质体核酸扩增测定允许定量和定性分析物检测。

69. 发明授权

US07582430B2 Immunoliposome-nucleic acid amplification (ILNAA) assay 失效
标题翻译：免疫脂质体 - 核酸扩增（ILNAA）检测
公开(公告)号：US07582430B2
公开(公告)日：2009-09-01
申请号：US10759099
申请日：2004-01-20
申请人： Timothy J. O'Leary , Jeffrey T. Mason
发明人： Timothy J. O'Leary , Jeffrey T. Mason
IPC分类号： C12Q1/68
CPC分类号： A61K9/127 , C12Q1/6806 , C12Q2563/161
摘要： Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.
摘要翻译：免疫脂质体及其在高度特异性和灵敏的核酸扩增测定中的应用，其依赖于在脂质体上的受体之后从包封在脂质体内释放的特异性核酸序列的扩增与固定在选择表面上的靶向分析物/抗原相结合。免疫脂质体核酸扩增测定允许定量和定性分析物检测。

70. 发明授权

US07309333B2 Medication delivery system having selective automated or manual discharge 失效
标题翻译：具有选择性自动或手动放电的药物输送系统
公开(公告)号：US07309333B2
公开(公告)日：2007-12-18
申请号：US10933619
申请日：2004-09-02
申请人： Jeffrey T. Mason
发明人： Jeffrey T. Mason
IPC分类号： A61M31/00
CPC分类号： A61M5/1454 , A61M5/1411 , A61M5/165 , A61M2005/1405
摘要： A portable medication delivery system enables a patient to elect slow continuous auto-administration or rapid bolus self-administration of a fluid medication. The medication delivery system has an infusion pump, which includes a fluid storage chamber and a spring-driven piston positioned in the fluid storage chamber. The fluid storage chamber is initially charged with the medication and the infusion pump automatically delivers a continuous dosage of the medication at a first flow rate over a long time from the fluid storage chamber to a treatment site in the patient. A bolus injector is positioned in series or in parallel with the infusion pump and is charged with a bolus dosage of the treatment fluid from the fluid storage chamber for alternate manual self-injection of the medication into the treatment site at a higher second flow rate for a short time. The infusion pump flowpath includes a drip chamber having an in-line flow restriction, which converts a continuous flow stream from the fluid storage chamber to a drip stream. A sight window in the drip chamber permits the user to visually confirm the flow of medication through the infusion pump.
摘要翻译：便携式药物输送系统使得患者能够选择缓慢的连续自动给药或快速推注流体药物的自我施用。药物输送系统具有输液泵，其包括流体储存室和定位在流体储存室中的弹簧驱动的活塞。液体储存室最初被充满药物，并且输液泵以长时间的第一流速自动地将药物的连续剂量从液体储存室输送到患者的治疗部位。推注注射器与输注泵串联或并联放置，并且从流体存储室中以大剂量的治疗流体装入，用于以更高的第二流速将药物交替地手动自我注射到治疗部位，用于很短的时间。输液泵流路包括具有直列流动限制的滴水室，其将来自流体储存室的连续流动流转换成滴流。滴液室中的视窗允许使用者通过输液泵目视确认药物的流动。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式