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1. 发明专利

GB238757A Improvements in crystal detector for wireless reception 未知
公开(公告)号：GB238757A
公开(公告)日：1925-08-27
申请号：GB2941424
申请日：1924-12-08
申请人： WILLIAM DAVID MCGOWAN
IPC分类号： H01L29/00
摘要： 238,757. McGowon, W. D. Dec. 8, 1924. Crystal detectors comprise a glass cylinder 21 containing one or more loose crystals to which contact is made on each side by metallic brushes 25. The bristles are set in a metallic plug 24 held in a resilient metal tube 22 provided with an operating knob 23. The edges of the tube overlap, and a notch 26 is cut to provide a springy tongue 27 which holds the brush member in any set position in metal tubes 11, 12 connected to terminals (not shown) by means of screws and metal straps in recesses under the base 10.

2. 发明授权

US09584055B2 Voltage regulator system for a genset 有权
标题翻译：发电机组电压调节系统
公开(公告)号：US09584055B2
公开(公告)日：2017-02-28
申请号：US14414709
申请日：2012-07-17
申请人： Alan Cooper , Keith Chambers , David McGowan , John Morrow
发明人： Alan Cooper , Keith Chambers , David McGowan , John Morrow
IPC分类号： H02P9/00 , H02P9/44 , H02P9/30
CPC分类号： H02P9/44 , H02J9/08 , H02P9/008 , H02P9/30 , H02P9/48
摘要： A voltage regulator system for regulating an output voltage of a genset includes a voltage regulator for reducing terminal voltage in response to a reduction in terminal frequency. A plurality of under-frequency roll-off (UFRO) states is provided in the voltage regulator, with each UFRO state being configured to implement a UFRO characteristic. An operational signal indicative of an operating condition of the genset forms the basis for selection of the UFRO characteristic.
摘要翻译：用于调节发电机组的输出电压的电压调节器系统包括用于响应于终端频率的降低而降低端电压的电压调节器。在电压调节器中提供多个低频滚降（UFRO）状态，每个UFRO状态被配置为实现UFRO特性。指示发电机组的运行状态的操作信号构成了用于选择UFRO特性的基础。

3. 发明授权

US08916575B2 Quinazoline derivatives for the treatment of viral infections and further diseases 有权
标题翻译：喹唑啉衍生物用于治疗病毒感染和进一步疾病
公开(公告)号：US08916575B2
公开(公告)日：2014-12-23
申请号：US14118527
申请日：2012-05-18
申请人： David McGowan , Pierre Jean-Marie Bernard Raboisson , Tim Hugo Maria Jonckers , Stefaan Julien Last , Werner Embrechts , Serge Maria Aloysius Pieters
发明人： David McGowan , Pierre Jean-Marie Bernard Raboisson , Tim Hugo Maria Jonckers , Stefaan Julien Last , Werner Embrechts , Serge Maria Aloysius Pieters
IPC分类号： A01N43/54 , C07D239/72 , C07D401/00
CPC分类号： C07D491/056 , C07D239/95 , C07D295/192 , C07D401/06 , C07D403/04
摘要： This invention relates to quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy of disorders in which the modulation of toll-like-receptors is involved.
摘要翻译：本发明涉及喹唑啉衍生物，其制备方法，药物组合物及其在治疗涉及toll样受体调节的病症中的用途。

4. 发明申请

US20140000924A1 High-Speed Data Cable With Shield Connection 有权
标题翻译：带屏蔽连接的高速数据线
公开(公告)号：US20140000924A1
公开(公告)日：2014-01-02
申请号：US14014187
申请日：2013-08-29
申请人： John Martin Horan , David McGowan , Padraig McDaid
发明人： John Martin Horan , David McGowan , Padraig McDaid
IPC分类号： H01B9/00 , H01B13/22
CPC分类号： H01B9/006 , H01B11/1091 , H01B13/22 , Y10T29/49117 , Y10T29/49169
摘要： A high speed cable with terminating assemblies at the respective ends of the cable includes a ground wire, one or more signal wires, and a conductive layer enclosing the ground wire and the signal wires. The ground wire as well as the signal wires and the conductive layer extend into the terminating assemblies, in each of which corresponding inductive elements are coupled between the conductive layer and the ground wire. In each terminating assembly, the ground wire is shunted to the conductive layer by inductive elements, thus providing added low frequency connectivity in the cable, while at the same time blocking high frequency noise energy that may be present in the ground wire and preventing it from being coupled into, and transmitted through, the conductive layer.
摘要翻译：具有端子组件的高速电缆在电缆的相应端部处包括接地线，一个或多个信号线，以及包围接地线和信号线的导电层。接地线以及信号线和导电层延伸到终端组件中，其中相应的感应元件耦合在导电层和接地线之间。在每个端接组件中，接地线通过电感元件分流到导电层，从而在电缆中提供附加的低频连接，同时阻挡可能存在于接地线中的高频噪声能量，耦合到导电层中并透过导电层。

5. 发明授权

US08436036B2 Diaryl ethers 有权
标题翻译：二芳基醚
公开(公告)号：US08436036B2
公开(公告)日：2013-05-07
申请号：US13265588
申请日：2010-04-23
申请人： Samuel Dominique Demin , David McGowan , Stefaan Julien Last , Pierre Jean-Marie Bernard Raboisson
发明人： Samuel Dominique Demin , David McGowan , Stefaan Julien Last , Pierre Jean-Marie Bernard Raboisson
IPC分类号： A61K31/4178 , C07D403/14
CPC分类号： C07D403/14
摘要： Compounds of the formula I: including any possible stereoisomers thereof, or a pharmaceutically acceptable salt and/or solvate thereof, as well as pharmaceutical formulations and the use of compounds of formula I as HCV inhibitors.
摘要翻译：式I的化合物：包括其任何可能的立体异构体，或其药学上可接受的盐和/或溶剂合物，以及药物制剂和式I化合物作为HCV抑制剂的用途。

6. 发明授权

US08272023B2 Startup circuit and high speed cable using the same 有权
标题翻译：启动电路和高速电缆使用相同
公开(公告)号：US08272023B2
公开(公告)日：2012-09-18
申请号：US12801434
申请日：2010-06-09
申请人： John Martin Horan , David McGowan
发明人： John Martin Horan , David McGowan
IPC分类号： H04N7/173
CPC分类号： H04L25/02 , G09G5/003 , G09G2370/12 , H04L25/03885 , H04L25/242 , H04N5/765 , H04N5/775
摘要： A High Definition Multimedia Interface (HDMI) cable carries high speed encoded data, which are transmitted differentially over data channels, along with a clock. A Mobile High-Definition Link (MHL) cable carries high speed data which are multiplexed to achieve smaller connectors with fewer pins. A MHL-to-HDMI cable is proposed, which includes an embedded MHL to HDMI adapter device for demultiplexing the received MHL-formatted signal and outputting an HDMI-formatted signal. The embedded circuit is powered by a combination of power sources, the power being harvested from the high-speed HDMI signals themselves, including a startup circuit harvesting power from a low speed HDMI signal when power from the high-speed HDMI signals is not available.
摘要翻译：高分辨率多媒体接口（HDMI）电缆承载高速编码数据，这些数据通过数据信道与时钟差分传输。移动高清晰度链路（MHL）电缆承载高速数据，这些数据被复用以实现具有较少引脚的较小连接器。提出了一种MHL至HDMI电缆，其包括嵌入式MHL至HDMI适配器装置，用于对接收到的MHL格式的信号进行解复用并输出HDMI格式的信号。嵌入式电路由电源组合供电，电源从高速HDMI信号本身收集，包括当来自高速HDMI信号的电源不可用时，从低速HDMI信号采集电力的启动电路。

7. 发明授权

US07674907B2 Furanopyridine derivatives and methods of use 有权
标题翻译：呋喃并吡啶衍生物和使用方法
公开(公告)号：US07674907B2
公开(公告)日：2010-03-09
申请号：US11184237
申请日：2005-07-18
申请人： Joseph J. Nunes , Matthew W. Martin , Ryan White , David McGowan , Jean E. Bemis , Frank Kayser , Jiasheng Fu , Jinqian Liu , XianYun Jiao
发明人： Joseph J. Nunes , Matthew W. Martin , Ryan White , David McGowan , Jean E. Bemis , Frank Kayser , Jiasheng Fu , Jinqian Liu , XianYun Jiao
IPC分类号： C07D491/048 , A61K31/4355
CPC分类号： C07D491/04 , C07D491/14
摘要： The present invention relates to furanopyridine compounds having the general Formula I: and stereoisomers, tautomers, solvates, pharmaceutically acceptable salts and derivatives, and prodrugs thereof. The invention also includes pharmaceutical compositions comprising a compound of Formula I, methods of modulating Lck and ACK-1 enzymes and of treating various related diseases and conditions, including inflammation, inhibition of T cell activation, proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease, Crohn's disease, lupus, hypersensitivity, type 1 diabetes, psoriasis, dermatitis, Hashimoto's thyroiditis, Sjogren's syndrome, autoimmune hyperthyroidism, Addison's disease, autoimmune diseases, glomerulonephritis, allergic diseases, asthma, hayfever, eczema, cancer, colon carcinoma, thymoma, just to name a few, in a mammal, comprising administering to the mammal a therapeutically effective amount a compound of Formula I, as described above, and methods of manufacturing medicaments comprising the compound of Formula I.
摘要翻译：本发明涉及具有通式I的呋喃并吡啶化合物及其立体异构体，互变异构体，溶剂合物，药用盐和衍生物及其前药。本发明还包括药物组合物，其包含式I化合物，调节Lck和ACK-1酶的方法以及治疗各种相关疾病和病症，包括炎症，T细胞活化抑制，增殖，关节炎，器官移植，缺血或再灌注损伤，心肌梗塞，中风，多发性硬化，炎性肠病，克罗恩病，狼疮，超敏反应，1型糖尿病，牛皮癣，皮炎，桥本氏甲状腺炎，干燥综合征，自身免疫性甲状腺功能亢进，艾迪生病，自身免疫性疾病，肾小球肾炎，过敏性疾病，哮喘，干草组织，湿疹，癌症，结肠癌，胸腺瘤，仅举几个例子，在哺乳动物中，包括向哺乳动物施用治疗有效量的如上所述的式I化合物和制备包含以下化合物的药物的方法：一级方程式

8. 发明授权

US08479248B2 Startup circuit and high speed cable using the same 有权
标题翻译：启动电路和高速电缆使用相同
公开(公告)号：US08479248B2
公开(公告)日：2013-07-02
申请号：US13573415
申请日：2012-09-14
申请人： John Martin Horan , David McGowan
发明人： John Martin Horan , David McGowan
IPC分类号： H04N7/173
CPC分类号： H04L25/02 , G09G5/003 , G09G2370/12 , H04L25/03885 , H04L25/242 , H04N5/765 , H04N5/775
摘要： A system for providing a power signal of a predetermined voltage to an input of a High Definition Multimedia Interface (HDMI) sink device is provided. The system includes an electronic device, generating HDMI signals transmitted on at least one differential signal line to another input of the HDMI sink device, and a startup circuit, providing the power signal of the predetermined voltage. The startup circuit includes a power harvesting circuit for obtaining an electrical power of a lower voltage, lower than the predetermined voltage, from at least one of the HDMI signals on the another input, and a voltage raiser circuit increasing the lower voltage to the predetermined voltage. A corresponding electronic cable containing the start-up circuit is also provided.
摘要翻译：提供了一种用于向高清晰度多媒体接口（HDMI）信宿设备的输入提供预定电压的功率信号的系统。该系统包括电子设备，产生在至少一个差分信号线上传输的HDMI信号到HDMI宿设备的另一个输入端，以及启动电路，提供预定电压的功率信号。启动电路包括从另一输入端的HDMI信号中的至少一个获得低于预定电压的较低电压的电力的电力收集电路，以及将较低电压增加到预定电压的升压电路。还提供了包含启动电路的相应电子电缆。

9. 发明申请

US20060241115A1 Compounds and methods of use 有权
公开(公告)号：US20060241115A1
公开(公告)日：2006-10-26
申请号：US11042634
申请日：2005-01-24
申请人： Michele Potashman , Tae-Seong Kim , Steven Bellon , Shon Booker , Yuan Cheng , Joseph Kim , Andrew Tasker , Ning Xi , Shimin Xu , Jean-Christophe Harmange , George Borg , Matthew Weiss , Brian Hodous , Russell Graceffa , William Buckner , Craig Masse , Deborah Choquette , Matthew Martin , Julie Germain , Lucian DiPietro , Stuart Chaffee , Joseph Nunes , John Buchanan , Gregory Habgood , David McGowan , Douglas Whittington
发明人： Michele Potashman , Tae-Seong Kim , Steven Bellon , Shon Booker , Yuan Cheng , Joseph Kim , Andrew Tasker , Ning Xi , Shimin Xu , Jean-Christophe Harmange , George Borg , Matthew Weiss , Brian Hodous , Russell Graceffa , William Buckner , Craig Masse , Deborah Choquette , Matthew Martin , Julie Germain , Lucian DiPietro , Stuart Chaffee , Joseph Nunes , John Buchanan , Gregory Habgood , David McGowan , Douglas Whittington
IPC分类号： A61K31/517 , A61K31/502 , A61K31/498 , A61K31/4709 , C07D43/02
CPC分类号： C07D213/64 , C07D213/81 , C07D215/233 , C07D215/38 , C07D215/48 , C07D215/54 , C07D237/34 , C07D239/34 , C07D239/47 , C07D239/84 , C07D239/94 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要： Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

10. 发明申请

US20060217380A1 Heteroaryl-substituted alkyne compounds and method of use 有权
标题翻译：杂芳基取代的炔化合物及其使用方法
公开(公告)号：US20060217380A1
公开(公告)日：2006-09-28
申请号：US11251490
申请日：2005-10-14
申请人： Stuart Chaffee , Brian Albrecht , Brian Hodous , Matthew Martin , David McGowan , Erin DiMauro , Gade Reddy , Victor Cee , Philip Olivieri , Anthony Reed , Karina Romero
发明人： Stuart Chaffee , Brian Albrecht , Brian Hodous , Matthew Martin , David McGowan , Erin DiMauro , Gade Reddy , Victor Cee , Philip Olivieri , Anthony Reed , Karina Romero
IPC分类号： A61K31/517 , A61K31/5377 , A61K31/503
CPC分类号： C07D213/74 , C07D213/81 , C07D215/14 , C07D239/42 , C07D241/42 , C07D401/06 , C07D401/12 , C07D403/10 , C07D403/12 , C07D405/06 , C07D409/06 , C07D413/12 , C07D417/12 , C07D471/04
摘要： The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation, cancer and related conditions. The compounds have a general Formula I wherein A1, A2, A3, A4, R1 and R2 are defined herein. Accordingly, the invention also comprises pharmaceutical compositions comprising the compounds of the invention, methods for the prophylaxis and treatment of kinase mediated diseases using the compounds and compositions of the invention, and intermediates and processes useful for the preparation of compounds of the invention.
摘要翻译：本发明包括一类新的可用于预防和治疗蛋白激酶介导的疾病，包括炎症，癌症和相关病症的化合物。化合物具有通式I，其中A 1，A 2，A 3，A 4，R 4，本文定义了SUP> 1和R 2。因此，本发明还包括含有本发明化合物的药物组合物，使用本发明化合物和组合物预防和治疗激酶介导的疾病的方法，以及可用于制备本发明化合物的中间体和方法。

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