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1. 发明专利

JP2005535336A Sequencing method using a polymerase with 3'-5 'exonuclease 审中-公开
公开(公告)号：JP2005535336A
公开(公告)日：2005-11-24
申请号：JP2004528265
申请日：2003-08-19
申请人：ジャン,シュウZhang,Xu
发明人：リ，カイ
IPC分类号： C12N15/09 , C12Q1/68
CPC分类号： C12Q1/6853 , C12Q1/6869 , C12Q2525/185 , C12Q2521/325 , C12Q2521/319
摘要：【課題】３'−５'エキソヌクレアーゼ活性を有するポリメラーゼを用いることよる遺伝子配列決定方法を提供する。
【解決手段】前記方法は、（１）３'末端が修飾された特異的なオリゴヌクレオチドプライマーセットを調製する工程と、（２）３'−５'エキソヌクレアーゼ活性を有するポリメラーゼ及び修飾されたプライマーからなる分子「オン／オフ」スイッチにより選択的プライマー伸長を行う工程と、（３）プライマー伸長反応の産物を可視化し遺伝子配列を決定工程とを含む。本発明で用いられる分子「オン／オフ」スイッチのフィデリティーは、校正活性を有さないポリメラーゼを用いる従来のプライマー伸長反応より高い。本方法は、既知でない配列を直接配列決定するのに用いることもでき、配列決定は既知の配列セグメントに依存しない。本方法において得られる各シグナルは、１個以上のヌクレオチドの配列情報を含む。本方法を用いて、単一ヌクレオチド多形分析及び遺伝子配列分析を大量処理スクリーニングで行うことができる。

2. 发明专利

FR3011093B1 LA SYSTEME DE FIXATION DE VERRE (LA FORME DE VAGUE) SUR LA MONTURE 未知
公开(公告)号：FR3011093B1
公开(公告)日：2016-10-28
申请号：FR1302229
申请日：2013-09-25
申请人： ZHANG XU
发明人： ZHANG XU
IPC分类号： G02C1/06

3. 发明专利

FR3011093A1 LA SYSTEME DE FIXATION DE VERRE (LA FORME DE VAGUE) SUR LA MONTURE 未知
公开(公告)号：FR3011093A1
公开(公告)日：2015-03-27
申请号：FR1302229
申请日：2013-09-25
申请人： ZHANG XU
发明人： ZHANG XU
IPC分类号： G02C1/06
摘要： La présente invention concerne une monture de lunettes comprenant une partie frontale (4) de monture avec la porte-plaquettes (6) et la porte-plaquettes (7) de lunettes dont une extrémité se divise en forme de vague de la porte-plaquettes (6) et la porte-plaquettes (7), la partie frontale (4) de monture présentant deux cerclages aptes à recevoir des verres (2) de lunettes avec une forme de vague de la porte-plaquettes (6) et la porte-plaquettes (7) et une plaquette (8) de lunette s'étendant selon une direction transversale par rapport au plan défini par la partie frontale (4) de monture, chaque cerclage étant fendu selon une fente de façon à permettre l'engagement ou le désengagement des verres (2) de lunettes de ladite partie frontale (4) de monture, ladite fente s'étendant dans l'élément de la porte-plaquettes (6) et la porte-plaquettes (7) de façon à définir une porte-plaquettes (7) d'élément de raccordement et une porte-plaquettes (6) d'élément de raccordement, les dites partie la porte-plaquettes (6) et la porte-plaquettes (7) étant enserrées entre la plaquette (8) de lunettes, caractérisé en ce que la partie frontale (4) de lunette comprend en outre pour chaque cerclage un élément de la porte-plaquettes (6) et la porte-plaquettes (7) au niveau de la fente, la porte-plaquettes (6) et la porte-plaquettes (7) consistant en au moins deux niveaux super ses de motifs complémentaires de part et d'autre de la fente et situés sensiblement dans le plan de la partie frontale (4) de monture, qui lorsqu'ils sont emboités ensemble prévissent un déplacement relatif des parties la porte-plaquettes (6) et la porte-plaquettes (7) de l'élément de raccordement selon ladite direction transversale par rapport au plan défini par la partie frontale (4) de monture.

4. 发明专利

IL277751D0 Method and apparatus for obtaining resource indication value 未知
公开(公告)号：IL277751D0
公开(公告)日：2020-11-30
申请号：IL27775120
申请日：2020-10-01
申请人： HUAWEI TECH CO LTD , CHEN ZHENG , ZHANG XU , LI HUA , XUE LIXIA
发明人： CHEN ZHENG , ZHANG XU , LI HUA , XUE LIXIA
IPC分类号： H04L5/00 , H04W72/04 , H04W72/12
摘要： This application provides a method and apparatus for obtaining a resource indication value. The method includes: receiving downlink control information, where the downlink control information includes a first resource indication value n, a quantity of bits of the first indication value n is determined based on a first bandwidth part, and the downlink control information is used to schedule a data channel located in a second bandwidth part; determining a second indication value r based on the first indication value n, where r = └±a·n + b ┘ or r = └a ·n J , a is a positive number, and b is a positive integer; and determining, based on the second indication value r, a resource occupied by the data channel. Flexibility of scheduling a data channel by a network device can be improved in this manner.

5. 发明专利

AU2003257798A1 USING A POLYMERASE WITH 3' TO 5' EXONUCLEASE ACTIVITY TO PERFORM GENE SEQUENCE ANALYSIS 未知
公开(公告)号：AU2003257798A1
公开(公告)日：2004-03-03
申请号：AU2003257798
申请日：2003-08-19
申请人： ZHANG XU
发明人： LI KAI
IPC分类号： C12N15/09 , C12Q1/68 , C12Q1/25
摘要： A method for gene sequence determination by utilizing polymerases with 3'to 5'exonuclease activity is disclosed, which comprises the following steps: (1) preparing sets of specific oligonucleotide primers with their 3 'termini being modified, (2) performing a selective primer extension with a molecular "on/off" switch consisting of polymerases with 3'to 5'exonuclease activities and the modified primers, and (3) visualizing the products of the primer extension reaction to determine the gene sequence. The fidelity of the molecular "on/off" switch employed in the present invention is higher than in the conventional primer extension reaction wherein polymerases without proofreading activity are employed. The present method can also be used to sequence an unknown sequence directly, and does not depend on a known segment of sequence for the sequencing. In this method, each signal obtained contains the sequence information of one or more nucleotides. Using this method, single nucleotide polymorphism assay and gene sequence analysis can be performed in high throughput screening.

6. 发明专利

CA2236995A1 CHORD-LIKE VIBRATION LOUDSPEAKER 未知
公开(公告)号：CA2236995A1
公开(公告)日：1999-10-24
申请号：CA2236995
申请日：1998-06-10
申请人： ZHANG LINA , ZHANG XIAFU , ZHANG XU
发明人： ZHANG LINA , ZHANG XIAFU , ZHANG XU
IPC分类号： H04R9/00 , H04R9/06 , H04R9/04
摘要： This invention is a loudspeaker that consists of some vibratory membranes and magnets. Every vibratory membrane is a part of a soft conductive tape and is put in a magnetic field. When the membranes conduct audio current, they vibrate air directly with their surfaces, and produce sound waves. This loudspeaker can be made into various shapes. It has overcome the defect of sound distortion caused by the diaphragm deformations in regular loudspeakers. Its distortion is lower, its transient response is excellent, and its voice quality and acoustic effects are admirable.

7. 发明公开

EP1536019A4 USING A POLYMERASE WITH 3' TO 5' EXONUCLEASE ACTIVITY TO PERFORM GENE SEQUENCE ANALYSIS 审中-公开
标题翻译：使用具有3“至5”EXONUKLEASEAKTIVITûT甲聚合酶之基因序列分析PERFORMING CURRENCY
公开(公告)号：EP1536019A4
公开(公告)日：2007-09-26
申请号：EP03787581
申请日：2003-08-19
申请人： ZHANG XU
发明人： LI KAI
IPC分类号： C12N15/09 , C12Q1/68 , C12Q1/25
CPC分类号： C12Q1/6853 , C12Q1/6869 , C12Q2525/185 , C12Q2521/325 , C12Q2521/319
摘要： The present invention discloses a method to carry out gene sequence analysis using a polymerase with 3' to 5' exonuclease activity, which comprises the following steps: a. Prepare specific primers set with their 3' terminal modified; b. Subject the polymerase with 3' to 5' exonuclease activity to form a molecular 'on/off' switch with the modified primers, and perform selective primer extension reactions with the involvement of the said molecular 'on/off' switch; c. Detect image of the primer extension products and analysis the sequences. With the molecular switch of the present method, the accuracy is higher than the conventionally employed primer extension reactions mediated by a polymerase without proofreading function; It can also be used for direct analysis of unknown sequences, and it needn't to rely on a segment of know sequence when sequencing with the present method; Every signal obtained in this method gives information for one of more base sequences; The present method provides a high throughput analysis approach for Single Nucleotide Polyphism assay and gene sequence analysis.

8. 发明公开

EP1536019A1 USING A POLYMERASE WITH 3' TO 5' EXONUCLEASE ACTIVITY TO PERFORM GENE SEQUENCE ANALYSIS 审中-公开
标题翻译：使用具有3“至5”EXONUKLEASEAKTIVITûT甲聚合酶之基因序列分析PERFORMING CURRENCY
公开(公告)号：EP1536019A1
公开(公告)日：2005-06-01
申请号：EP03787581.2
申请日：2003-08-19
申请人： Zhang, Xu
发明人： LI, Kai
IPC分类号： C12Q1/25 , C12Q1/68
CPC分类号： C12Q1/6853 , C12Q1/6869 , C12Q2525/185 , C12Q2521/325 , C12Q2521/319
摘要： A method for gene sequence determination by utilizing polymerases with 3'to 5'exonuclease activity is disclosed, which comprises the following steps: (1) preparing sets of specific oligonucleotide primers with their 3 'termini being modified, (2) performing a selective primer extension with a molecular "on/off" switch consisting of polymerases with 3'to 5'exonuclease activities and the modified primers, and (3) visualizing the products of the primer extension reaction to determine the gene sequence. The fidelity of the molecular "on/off" switch employed in the present invention is higher than in the conventional primer extension reaction wherein polymerases without proofreading activity are employed. The present method can also be used to sequence an unknown sequence directly, and does not depend on a known segment of sequence for the sequencing. In this method, each signal obtained contains the sequence information of one or more nucleotides. Using this method, single nucleotide polymorphism assay and gene sequence analysis can be performed in high throughput screening.
摘要翻译：通过用3'端5'exonuclease活性利用聚合酶的基因序列测定的方法是游离缺失盘，其包括以下步骤：（1）的特定寡核苷酸引物制备设置与它们的3“末端被修饰，（2）进行选择性引物扩展了“开/关”开关由具有3'端5'exonuclease活动和修饰的引物的聚合酶，以及（3）可视化所述引物延伸反应，以确定性矿基因序列的产物分子。 “开/关”在本发明中使用的开关的分子的保真度比没有校正活性被采用常规的引物延伸反应的聚合酶worin更高。本发明的方法因此可以用于测序直接序列未知的，并且不依赖于序列的用于测序的已知段。在该方法中，获得的每个信号包含一个或多个核苷酸的序列信息。使用这种方法，单核苷酸多态性测定和基因序列分析可以在高通量筛选进行。

9. 发明申请

WO2022159101A1 FUEL CELL GAS DIFFUSION LAYERS 审中-公开
公开(公告)号：WO2022159101A1
公开(公告)日：2022-07-28
申请号：PCT/US2021/014624
申请日：2021-01-22
申请人： ROBERT BOSCH GMBH , CHENG, Lei , LI, Xiaobai , JOHNSTON, Christina , CHEN, Bicheng , RIKIYA, Yoshida , SHINICHI, Makino , ZHANG, Xu , CHRISTENSEN, Jake
发明人： CHENG, Lei , LI, Xiaobai , JOHNSTON, Christina , CHEN, Bicheng , RIKIYA, Yoshida , SHINICHI, Makino , ZHANG, Xu , CHRISTENSEN, Jake
IPC分类号： H01M8/0234 , H01M8/0258 , H01M8/1018
摘要： A fuel cell includes a gas diffusion layer (GDL) situated between a catalyst layer of the fuel cell and a flow field plate of the fuel cell. The GDL has a first region and a second region along a thickness direction of the fuel cell. The first region is adjacent to the catalyst layer and has a first thermal conductivity. The second region is adjacent to the flow field plate and has a second thermal conductivity lower than the first thermal conductivity.

10. 发明申请

WO2019183914A1 DYNAMIC VIDEO ENCODING AND VIEW ADAPTATION IN WIRELESS COMPUTING ENVIRONMENTS 审中-公开
公开(公告)号：WO2019183914A1
公开(公告)日：2019-10-03
申请号：PCT/CN2018/081235
申请日：2018-03-30
申请人： INTEL CORPORATION , GAO, Jie , TANG, Wenyi , QIU, Bo , KARACAOGLU, Ulun , FLEMING, Kristoffer , LIN, Yunbiao , ZHOU, Yongfa , FRISHMAN, Yaniv , HIRANANDANI, Manish , ZHANG, Xu , TALMOR-MARKOVICH, Sharon , YANG, Jianwei , YANG, Yu , WANG, Yating
发明人： GAO, Jie , TANG, Wenyi , QIU, Bo , KARACAOGLU, Ulun , FLEMING, Kristoffer , LIN, Yunbiao , ZHOU, Yongfa , FRISHMAN, Yaniv , HIRANANDANI, Manish , ZHANG, Xu , TALMOR-MARKOVICH, Sharon , YANG, Jianwei , YANG, Yu , WANG, Yating
IPC分类号： H04N21/647
摘要： A mechanism is described for facilitating adjustment of video encoding rates and adaption of views in computing environments according to one embodiment. An apparatus of embodiments, as described herein, includes logic to track data associated with movement of a computing device accessible to a user, and logic to evaluate the data and compare a latency with latency thresholds, where the data indicates the latency and the latency thresholds associated with a frame. The apparatus further includes logic to maintain a current video encoding rate, if the latency is lower than a first latency threshold and greater than a second latency threshold. The current video encoding rate is decreased if the latency is equal to or greater than the first latency threshold, where the current video encoding rate is increased if the latency is lower than the second latency threshold. The apparatus further includes logic to present the frame at the computing device including one or more of a wearable device and a mobile device.

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