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1. 发明申请

US20120102593A1 Use of a Histone Deacetylase Gene OsHDT1 in Enhancing Rice Heterosis 审中-公开
标题翻译：使用组蛋白脱乙酰酶基因OsHDT1来增强水稻杂种优势
公开(公告)号：US20120102593A1
公开(公告)日：2012-04-26
申请号：US13266914
申请日：2010-04-29
申请人： Daoxiu Zhou , Chen Li , Limin Huang
发明人： Daoxiu Zhou , Chen Li , Limin Huang
IPC分类号： A01H5/00 , C12N5/10 , A01H1/06 , A01H5/10
CPC分类号： C12N9/16 , C12N15/8261 , C12N15/8289 , Y02A40/146
摘要： A histone deacetylase gene OsHDT1 which enhances utilization of heterosis in rice is isolated and cloned, said gene consisting of: 1) the DNA sequence of positions 1-894 in SEQ ID NO:1 in the Sequence listing; or 2) a DNA sequence which encodes the same protein as that encoded by the DNA sequence of 1). The histone deacetylase gene OsHDT1 is associated with enhanced utilization of heterosis in rice. When the transgenic plants having no phenotype were crossed with “Zhenshan 97A”, the F1 overexpression hybrid plants have obviously earlier flowering period than F1 wild-type hybrid plants. Moreover, the RNAi inhibition hybrid plants have a decreased seed setting rate compared to the negative control hybrid plants, while the parent RNAi inhibition plants and negative control plants shows no evident difference in the trait of seed setting rate. Western blotting revealed that the gene is capable of deacetylating histone, mainly at H4K16 site. In addition, there exist significant differences in the level of histone modification among “Minghui 63”, “Zhenshan 97” and “Shanyou63”.
摘要翻译：分离并克隆提高水稻利用率的组蛋白脱乙酰酶基因OsHDT1，该基因由以下组成：1）序列表中SEQ ID NO：1中1-894位的DNA序列; 或2）编码与由1）的DNA序列编码的蛋白相同的蛋白质的DNA序列。组蛋白脱乙酰酶基因OsHDT1与水稻中杂种优势的利用有关。当没有表型的转基因植物与“珍山97A”杂交时，F1过表达杂交植物的开花期明显比F1野生型杂种植物早。此外，与阴性对照杂交植物相比，RNAi抑制杂交植物的种子定形率降低，而亲本RNAi抑制植物和阴性对照植物在种子定形率的性状上没有显示出明显的差异。蛋白质印迹显示该基因能够脱乙酰化组蛋白，主要在H4K16位点。此外，“明辉63”，“贞山97”，“汕优63”组蛋白修饰水平存在显着差异。

2. 发明授权

US09410975B2 Pressure manifold to equalize pressure in integration PCR-CE microfluidic devices 有权
标题翻译：集成PCR-CE微流体装置的压力歧管以均衡压力
公开(公告)号：US09410975B2
公开(公告)日：2016-08-09
申请号：US12600171
申请日：2008-05-15
申请人： Chen Li , Samuel Chan , Jian Ping Zhang
发明人： Chen Li , Samuel Chan , Jian Ping Zhang
IPC分类号： B01L3/00 , G01N27/26 , G01N35/10 , C12P19/34 , G01N35/00
CPC分类号： G01N35/1095 , B01L3/502707 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L2200/027 , B01L2200/0684 , B01L2300/0645 , B01L2300/0819 , B01L2400/0487 , B01L2400/049 , G01N2035/00158 , G01N2035/00237
摘要： A device is presented that includes a chip having a plurality of wells that are optionally connected by capillary channels, and a manifold member configured to be disposed over the chip for equalizing pressure over the wells and capillary channels.
摘要翻译：提出了一种装置，其包括具有可选地通过毛细管通道连接的多个阱的芯片，以及配置成设置在芯片上方以均衡孔和毛细通道上的压力的歧管构件。

3. 发明授权

US08919655B2 Radio frequency identification (RFID) tag and manufacturing methods thereof 有权
标题翻译：射频识别（RFID）标签及其制造方法
公开(公告)号：US08919655B2
公开(公告)日：2014-12-30
申请号：US13884969
申请日：2011-03-14
申请人： Chen Li , Yong Wang , Shoumian Chen
发明人： Chen Li , Yong Wang , Shoumian Chen
IPC分类号： G06K19/02 , G06K19/077
CPC分类号： G06K19/07771 , G06K19/0775 , G06K19/07775
摘要： A radio frequency identification (RFID) device is disclosed. The RFID device includes a silicon substrate having a top side and a bottom side. The RFID device also includes a plurality of circuitry layers formed on the top side of the substrate, and the plurality of circuitry layers include at least a core circuitry and an on-chip antenna. Further, the RFID device includes a plurality of deep openings formed in the substrate on the bottom side under the plurality of circuitry layers. The plurality of deep openings are arranged in an array and through a substantial portion of the substrate, and a remaining portion of the substrate unreached by the plurality of deep openings separates the plurality of deep openings and the plurality of circuitry layers.
摘要翻译：公开了射频识别（RFID）设备。 RFID装置包括具有顶侧和底侧的硅衬底。 RFID设备还包括形成在衬底的顶侧上的多个电路层，并且多个电路层至少包括核心电路和片上天线。此外，RFID装置包括在多个电路层下方的底侧上的基板中形成的多个深开口。多个深开口以阵列布置并且穿过基底的大部分，并且未被多个深开口未被接触的基底的剩余部分分离出多个深开口和多个电路层。

4. 发明申请

US20140037938A1 Carbon Nanotube Enabled Hydrophobic-Hydrophilic Composite Interfaces and Methods of Their Formation 审中-公开
标题翻译：碳纳米管启用疏水 - 亲水性复合界面及其形成方法
公开(公告)号：US20140037938A1
公开(公告)日：2014-02-06
申请号：US13954214
申请日：2013-07-30
申请人： Chen Li , Xinyu Huang , Xianming Dai , Fanghao Yang
发明人： Chen Li , Xinyu Huang , Xianming Dai , Fanghao Yang
IPC分类号： C09D7/12
CPC分类号： C09D7/68 , B82Y30/00 , B82Y40/00 , C01B32/174 , C08K3/041 , C08K7/06 , C08K2201/011 , C09D5/00 , C09D7/62 , C09D7/67 , Y10T428/25
摘要： Methods are generally provided for forming a coated substrate having a plurality of carbon nanoparticles, along with the resulting coated substrates. In one embodiment, the method includes oxidizing the carbon nanoparticles to form oxygen containing end groups on the surfaces of the carbon nanoparticles; dispersing the oxidized carbon nanoparticles into a polymeric media to form an ink; and depositing the ink onto a substrate to form a coating. Generally, the coating includes the oxidized carbon nanoparticles dispersed within the polymeric material.
摘要翻译：通常提供用于形成具有多个碳纳米颗粒的涂覆基材以及所得涂覆的基材的方法。在一个实施方案中，该方法包括在碳纳米颗粒的表面上氧化碳纳米颗粒以形成含氧端基; 将氧化的碳纳米颗粒分散到聚合物介质中以形成油墨; 并将油墨沉积到基底上以形成涂层。通常，涂层包括分散在聚合材料内的氧化的碳纳米颗粒。

5. 发明授权

US08631035B2 Method for efficiently supporting interactive, fuzzy search on structured data 有权
标题翻译：有效支持结构化数据的交互式，模糊搜索的方法
公开(公告)号：US08631035B2
公开(公告)日：2014-01-14
申请号：US13295767
申请日：2011-11-14
申请人： Chen Li , Shengyue Ji , Guoliang Li , Jiannan Wang , Jianhua Feng
发明人： Chen Li , Shengyue Ji , Guoliang Li , Jiannan Wang , Jianhua Feng
IPC分类号： G06F17/30
CPC分类号： G06F17/273 , G06F17/30675
摘要： A method to support efficient, interactive, and fuzzy search on text data includes an interactive, fuzzy search on structured data used in applications such as query relaxation, autocomplete, and spell checking, where inconsistencies and errors exist in user queries as well as data. It utilizes techniques to efficiently and interactively answer fuzzy queries on structured data to allow users to efficiently search for information interactively, and they can find records and documents even if these records and documents are slightly different from the user keywords.
摘要翻译：支持对文本数据进行高效，交互和模糊搜索的方法包括在用户查询和数据中存在不一致和错误的应用程序中使用的结构化数据的交互式模糊搜索，如查询放松，自动填充和拼写检查。它利用技术来有效地和交互地回答结构化数据上的模糊查询，以允许用户以交互方式高效地搜索信息，即使这些记录和文档与用户关键字略有不同，它们也可以查找记录和文档。

6. 发明授权

US08383639B2 HIV integrase inhibitors 有权
标题翻译： HIV整合酶抑制剂
公开(公告)号：US08383639B2
公开(公告)日：2013-02-26
申请号：US12901147
申请日：2010-10-08
申请人： B. Narasimhulu Naidu , Kevin Peese , Ira B. Dicker , Chen Li , Manoj Patel , Nicholas A. Meanwell , Michael A. Walker
发明人： B. Narasimhulu Naidu , Kevin Peese , Ira B. Dicker , Chen Li , Manoj Patel , Nicholas A. Meanwell , Michael A. Walker
IPC分类号： A01N43/54 , A61K31/505
CPC分类号： C07D498/04 , C07D413/04
摘要： The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
摘要翻译：本公开一般涉及式I的新化合物，包括其盐，其抑制HIV整合酶并防止病毒整合入人DNA。这种作用使这些化合物可用于治疗艾滋病毒和艾滋病。本发明还包括用于治疗感染HIV的那些的药物组合物和方法。

7. 发明申请

US20120226042A1 Perylene-based Semiconducting Materials 有权
标题翻译：苝基半导体材料
公开(公告)号：US20120226042A1
公开(公告)日：2012-09-06
申请号：US13412023
申请日：2012-03-05
申请人： Helmut Reichelt , Thomas Geßner , Klaus Müllen , Chen Li , Glauco Battagliarin
发明人： Helmut Reichelt , Thomas Geßner , Klaus Müllen , Chen Li , Glauco Battagliarin
IPC分类号： C07D471/06 , C07F5/04
CPC分类号： C07F5/025 , C07D471/06
摘要： The present invention provides a compound of formula The compound of formula (1) is suitable for use as semiconducting material, in particular in electronic devices.
摘要翻译：本发明提供式的化合物式（1）化合物适合用作半导体材料，特别是在电子器件中。

8. 发明授权

US08235586B2 Smart card watch 有权
标题翻译：智能卡手表
公开(公告)号：US08235586B2
公开(公告)日：2012-08-07
申请号：US12736307
申请日：2009-03-25
申请人： Chen Li , Lucas Alexander Karl Scheybal
发明人： Chen Li , Lucas Alexander Karl Scheybal
IPC分类号： G04B37/00
CPC分类号： G04G21/00 , G04G17/08 , G04G21/04
摘要： A smart card watch comprises a watch head (1) and straps (2). A timepiece device and a smart card device are provided in the watch head (1), and a card slot (126) is provided on the side of the watch head (1). People can easily carry the smart card (153) with the watch which cannot be lost easily and they can conveniently change smart cards having different functions any time and anywhere they want. The smart card has great functions and can be used and operated easily. Furthermore, the timepiece device and the smart card device are installed in separate sealed chambers, a first chamber (14) and a second chamber (15) in the watch head (1), thus the timepiece device can be well protected such that it has a prolonged endurance and an ensured working stability. Even if the backcover (13) is opened to repair the smart card device, the normal operation of the timepiece device and the water-tightness of the first chamber (14) are not affected. Besides, the watch head (1) is further provided with a port (154), in particular USB port, which can get access to the service provider's websites via an external computer for electronic data communication and data updates of related services.
摘要翻译：智能卡手表包括手表头（1）和带子（2）。在钟表头（1）中设置有钟表装置和智能卡装置，并且在手表头（1）的一侧设置卡槽（126）。人们可以轻松地携带智能卡（153），手表不容易丢失，他们可以随时随地方便地更换具有不同功能的智能卡。智能卡功能强大，易于使用和操作。此外，钟表装置和智能卡装置安装在手表头（1）中的分离的密封室，第一室（14）和第二室（15）中，因此钟表装置可以被良好地保护，使得其具有延长耐力和确保工作稳定性。即使打开后盖（13）来修理智能卡装置，钟表装置的正常操作和第一室（14）的防水性也不受影响。此外，手表头（1）还设有端口（154），特别是USB端口，其可以经由外部计算机访问服务提供商的网站，用于电子数据通信和相关服务的数据更新。

9. 发明授权

US07996000B1 Managing page sizes for a mobile device using estimation of content customizer techniques 有权
标题翻译：使用内容定制器技术的估计来管理移动设备的页面大小
公开(公告)号：US07996000B1
公开(公告)日：2011-08-09
申请号：US11537003
申请日：2006-09-29
申请人： Micah Dubinko , Chen Li , Heidi Ann Pollock , James Liang , Jeff Leung , Michael Jeremy Temkin , Cynthia Johanson , Zhaowei Charlie Jiang , Boaz Aharon Shaham , Hei Chan
发明人： Micah Dubinko , Chen Li , Heidi Ann Pollock , James Liang , Jeff Leung , Michael Jeremy Temkin , Cynthia Johanson , Zhaowei Charlie Jiang , Boaz Aharon Shaham , Hei Chan
IPC分类号： H04L29/12 , G06F15/16 , G06F3/14 , G06F17/27
CPC分类号： H04L67/2823 , G06F17/30905 , H04W4/18
摘要： A network device, system, and method are directed towards enabling a determination for page size tailoring of content based, in part, on estimating of effects of processes applicable to preparing the content for use on a specified mobile device. Before performing the processes on the content, an estimation of the effects of the configuring processes may be determined. If the estimated content size is determined to be too large for the specified mobile device's memory footprint, page tailoring techniques may be applied to the content. Such page tailoring techniques may include stretching the content across a plurality of files, discarding a portion of the content, reducing portions of the content, or the like. Various processes may then be applied to the content to configure it for use on the specified mobile device.
摘要翻译：网络设备，系统和方法旨在使得能够基于估计可用于准备在特定移动设备上使用的内容的过程的效果的估计来确定内容的页面大小定制。在对内容执行处理之前，可以确定配置处理的影响的估计。如果对于指定的移动设备的存储器占用，估计的内容大小被确定为太大，则页面裁剪技术可以应用于内容。这种页面裁剪技术可以包括跨越多个文件拉伸内容，丢弃内容的一部分，缩小内容的部分等。然后可以将各种处理应用于内容以将其配置为在指定的移动设备上使用。

10. 发明授权

US07893055B2 HIV integrase inhibitors 有权
标题翻译： HIV整合酶抑制剂
公开(公告)号：US07893055B2
公开(公告)日：2011-02-22
申请号：US11768458
申请日：2007-06-26
申请人： Michael A. Walker , Chen Li , Katharine A. Grant-Young , John D. Matiskella , B. Narasimhulu Naidu , Jacques Banville , Francis Beaulieu , Carl Ouellet , Annapurna Pendri , Roger Remillard , Yasutsugu Ueda , Ting T. Yin
发明人： Michael A. Walker , Chen Li , Katharine A. Grant-Young , John D. Matiskella , B. Narasimhulu Naidu , Jacques Banville , Francis Beaulieu , Carl Ouellet , Annapurna Pendri , Roger Remillard , Yasutsugu Ueda , Ting T. Yin
IPC分类号： A61P31/00 , A61K31/535 , C07D498/02
CPC分类号： C07D487/04 , C07D471/10 , C07D498/04
摘要： The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
摘要翻译：本发明包括抑制HIV整合酶并防止病毒整合入人DNA的式I的系列双环嘧啶酮化合物。这种作用使这些化合物可用于治疗艾滋病毒和艾滋病。本发明还包括用于治疗感染HIV的那些的药物组合物和方法。

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