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1. 发明申请

US20120102593A1 Use of a Histone Deacetylase Gene OsHDT1 in Enhancing Rice Heterosis 审中-公开
标题翻译：使用组蛋白脱乙酰酶基因OsHDT1来增强水稻杂种优势
公开(公告)号：US20120102593A1
公开(公告)日：2012-04-26
申请号：US13266914
申请日：2010-04-29
申请人： Daoxiu Zhou , Chen Li , Limin Huang
发明人： Daoxiu Zhou , Chen Li , Limin Huang
IPC分类号： A01H5/00 , C12N5/10 , A01H1/06 , A01H5/10
CPC分类号： C12N9/16 , C12N15/8261 , C12N15/8289 , Y02A40/146
摘要： A histone deacetylase gene OsHDT1 which enhances utilization of heterosis in rice is isolated and cloned, said gene consisting of: 1) the DNA sequence of positions 1-894 in SEQ ID NO:1 in the Sequence listing; or 2) a DNA sequence which encodes the same protein as that encoded by the DNA sequence of 1). The histone deacetylase gene OsHDT1 is associated with enhanced utilization of heterosis in rice. When the transgenic plants having no phenotype were crossed with “Zhenshan 97A”, the F1 overexpression hybrid plants have obviously earlier flowering period than F1 wild-type hybrid plants. Moreover, the RNAi inhibition hybrid plants have a decreased seed setting rate compared to the negative control hybrid plants, while the parent RNAi inhibition plants and negative control plants shows no evident difference in the trait of seed setting rate. Western blotting revealed that the gene is capable of deacetylating histone, mainly at H4K16 site. In addition, there exist significant differences in the level of histone modification among “Minghui 63”, “Zhenshan 97” and “Shanyou63”.
摘要翻译：分离并克隆提高水稻利用率的组蛋白脱乙酰酶基因OsHDT1，该基因由以下组成：1）序列表中SEQ ID NO：1中1-894位的DNA序列; 或2）编码与由1）的DNA序列编码的蛋白相同的蛋白质的DNA序列。组蛋白脱乙酰酶基因OsHDT1与水稻中杂种优势的利用有关。当没有表型的转基因植物与“珍山97A”杂交时，F1过表达杂交植物的开花期明显比F1野生型杂种植物早。此外，与阴性对照杂交植物相比，RNAi抑制杂交植物的种子定形率降低，而亲本RNAi抑制植物和阴性对照植物在种子定形率的性状上没有显示出明显的差异。蛋白质印迹显示该基因能够脱乙酰化组蛋白，主要在H4K16位点。此外，“明辉63”，“贞山97”，“汕优63”组蛋白修饰水平存在显着差异。

2. 发明授权

US09108850B2 Preparing nanoparticles and carbon nanotubes 有权
标题翻译：制备纳米颗粒和碳纳米管
公开(公告)号：US09108850B2
公开(公告)日：2015-08-18
申请号：US13299875
申请日：2011-11-18
申请人： Stephen O'Brien , Limin Huang , Brian Edward White , Samuel Jonas Wind
发明人： Stephen O'Brien , Limin Huang , Brian Edward White , Samuel Jonas Wind
IPC分类号： B05D3/02 , C01B31/02 , B82Y30/00 , B82Y40/00
CPC分类号： C01B31/0233 , B82Y30/00 , B82Y40/00 , C01B32/162 , C01B2202/02 , C01B2202/34 , C01B2202/36 , Y10T428/24802
摘要： Apparatus and methods for forming the apparatus include nanoparticles, catalyst nanoparticles, carbon nanotubes generated from catalyst nanoparticles, and methods of fabrication of such nanoparticles and carbon nanotubes.
摘要翻译：用于形成装置的装置和方法包括纳米颗粒，催化剂纳米颗粒，由催化剂纳米颗粒产生的碳纳米管，以及制备这种纳米颗粒和碳纳米管的方法。

3. 发明授权

US08367034B2 Methods for preparing single-walled carbon nanotubes 失效
标题翻译：制备单壁碳纳米管的方法
公开(公告)号：US08367034B2
公开(公告)日：2013-02-05
申请号：US11628256
申请日：2005-06-03
申请人： Stephen O'Brien , Limin Huang , Brian Edward White
发明人： Stephen O'Brien , Limin Huang , Brian Edward White
IPC分类号： D01F9/127 , B01J21/08 , B01J23/88 , B01J23/75 , B82B1/00
CPC分类号： B01J29/0341 , B01J23/882 , B01J37/0215 , B01J37/0248 , B82Y30/00 , B82Y40/00 , C01B32/162 , C01B2202/02 , C01B2202/34 , C01B2202/36
摘要： The present invention relates to cobalt and molybdenum doped mesoporous silica catalysts and methods for using the catalysts to making Single-Walled Carbon Nanotubes. The methods offer increased control over the orientation, length and diameter of the nanotubes produced.
摘要翻译：本发明涉及掺钴和钼掺杂介孔二氧化硅催化剂以及使用该催化剂制备单壁碳纳米管的方法。这些方法提高了对所制备的纳米管的取向，长度和直径的控制。

4. 发明申请

US20100135937A1 METAL OXIDE NANOCRYSTALS: PREPARATION AND USES 审中-公开
标题翻译：金属氧化物纳米晶体：制备和使用
公开(公告)号：US20100135937A1
公开(公告)日：2010-06-03
申请号：US12566135
申请日：2009-09-24
申请人： Stephen O'Brien , Limin Huang , Zhuoying Chen , Ioannis Kymissis , Zhang Jia
发明人： Stephen O'Brien , Limin Huang , Zhuoying Chen , Ioannis Kymissis , Zhang Jia
IPC分类号： A61K8/19 , H01L51/30 , H01L27/07 , H01L29/92 , H01G9/00 , H01G4/06 , C09K3/00 , C01B13/00 , C01G25/02 , C01F17/00 , C01G45/12 , C01G49/02 , C01G53/04 , C01G51/04 , C01G23/04 , C01G19/02 , C01G41/02 , C01G11/02 , C01G31/02 , B32B27/32 , H01L21/302 , B05D5/12
CPC分类号： H01L21/02282 , A61K8/02 , A61K8/27 , A61K2800/413 , A61Q17/04 , B82Y5/00 , B82Y30/00 , C01B13/32 , C01D15/00 , C01D15/02 , C01G1/02 , C01G3/006 , C01G19/00 , C01G23/003 , C01G23/006 , C01G25/00 , C01G25/006 , C01G33/00 , C01G45/02 , C01G45/1264 , C01G49/0018 , C01G49/0054 , C01G51/70 , C01P2002/34 , C01P2002/72 , C01P2002/82 , C01P2002/86 , C01P2004/04 , C01P2004/51 , C01P2004/64 , C01P2006/40 , H01G9/058 , H01G11/46 , H01L21/02172 , H01L21/02181 , H01L21/02183 , H01L21/02186 , H01L21/02189 , H01L21/02192 , H01L21/02197 , H01L21/02205 , H01L21/31691 , H01L28/40 , H01L29/4908 , H01L29/516 , H01L51/0525 , Y02E60/13
摘要： Nanocrystalline forms of metal oxides, including binary metal oxide, perovskite type metal oxides, and complex metal oxides, including doped metal oxides, are provided. Methods of preparation of the nanocrystals are also provided. The nanocrystals, including uncapped and uncoated metal oxide nanocrystals, can be dispersed in a liquid to provide dispersions that are stable and do not precipitate over a period of time ranging from hours to months. Methods of preparation of the dispersions, and methods of use of the dispersions in forming films, are likewise provided. The films can include an organic, inorganic, or mixed organic/inorganic matrix. The films can be substantially free of all organic materials. The films can be used as coatings, or can be used as dielectric layers in a variety of electronics applications, for example as a dielectric material for an ultracapacitor, which can include a mesoporous material. Or the films can be used as a high-K dielectric in organic field-effect transistors. In various embodiments, a layered gate dielectric can include spin-cast (e.g., 8 nm-diameter) high-K BaTiO3 nanocrystals and parylene-C for pentacene OFETs.
摘要翻译：提供包括二元金属氧化物，钙钛矿型金属氧化物和复合金属氧化物的纳米晶体形式的金属氧化物，包括掺杂的金属氧化物。还提供了制备纳米晶体的方法。包括未加封和未涂覆的金属氧化物纳米晶体的纳米晶体可以分散在液体中以提供在几小时至数月的时间段内稳定且不沉淀的分散体。制备分散体的方法以及分散体在成膜中的使用方法同样被提供。膜可以包括有机，无机或混合的有机/无机基质。膜可以基本上不含所有有机材料。这些膜可以用作涂层，或者可以用作各种电子应用中的介电层，例如用作超级电容器的介电材料，其可以包括介孔材料。或者这些膜可以用作有机场效应晶体管中的高K电介质。在各种实施例中，分层栅极电介质可以包括旋转浇铸（例如，8nm直径）的高K BaTiO 3纳米晶体和对于并五苯OFET的对二甲苯-C。

5. 发明申请

US20090297626A1 Methods for preparing metal oxides 审中-公开
标题翻译：制备金属氧化物的方法
公开(公告)号：US20090297626A1
公开(公告)日：2009-12-03
申请号：US11982842
申请日：2007-11-05
申请人： Stephen O'Brien , Limin Huang
发明人： Stephen O'Brien , Limin Huang
IPC分类号： A61K33/30 , C01G9/02 , C01G23/047 , A61K33/24 , C09K3/00 , C07F7/28 , C07F3/06
CPC分类号： A61K33/24 , A61K33/30 , B82Y30/00 , C01B13/32 , C01G9/02 , C01G23/053 , C01P2002/54 , C01P2002/72 , C01P2002/84 , C01P2004/03 , C01P2004/04 , C01P2004/64 , C09C1/043
摘要： The disclosed subject matter provides a method for preparing a metal oxide, the method includes (a) contacting a metal salt precursor with an alcohol to provide a metal oxide; and (b) removing the metal oxide from the alcohol.
摘要翻译：所公开的主题提供了制备金属氧化物的方法，该方法包括（a）使金属盐前体与醇接触以提供金属氧化物; 和（b）从醇中除去金属氧化物。

6. 发明申请

US20080069760A1 Methods For Preparing Single -Walled Carbon Nanoturbes 失效
标题翻译：单壁碳纳米管制备方法
公开(公告)号：US20080069760A1
公开(公告)日：2008-03-20
申请号：US11628256
申请日：2005-06-03
申请人： Stephen O'Brien , Limin Huang , Brian White
发明人： Stephen O'Brien , Limin Huang , Brian White
IPC分类号： C01B31/00 , B01J21/08
CPC分类号： B01J29/0341 , B01J23/882 , B01J37/0215 , B01J37/0248 , B82Y30/00 , B82Y40/00 , C01B32/162 , C01B2202/02 , C01B2202/34 , C01B2202/36
摘要： The present invention relates to cobalt and molybdenum doped mesoporous silica catalysts and methods for using the catalysts to making Single-Walled Carbon Nanotubes. The methods offer increased control over the orientation, length and diameter of the nanotubes produced.
摘要翻译：本发明涉及掺钴和钼掺杂介孔二氧化硅催化剂以及使用该催化剂制备单壁碳纳米管的方法。这些方法提高了对所制备的纳米管的取向，长度和直径的控制。

7. 发明申请

US20190314491A1 RECOMBINANT RSV ANTIGENS, NUCLEIC ACID MOLECULES ENCODING THE ANTIGENS, AND VACCINE COMPOSITIONS COMPRISING THE SAME 审中-公开
公开(公告)号：US20190314491A1
公开(公告)日：2019-10-17
申请号：US16462757
申请日：2017-11-22
申请人： Limin Huang
发明人： Limin Huang , Jenmin Huang
IPC分类号： A61K39/155 , C07K14/135 , C12N15/85
摘要： Provided is an antigen including a recombinant respiratory syncytial virus (RSV) F protein, wherein the recombinant RSV F protein includes an antigenic region flanked with an HRN region and an HRC region, and the antigenic region includes one or more antigenic sites selected from the group consisting of site Ø, site II, and site IV. The present disclosure also provides a nucleic acid molecule encoding the antigen and a vaccine composition including the antigen for eliciting an immune response against RSV.

8. 发明申请

US20120126199A1 PREPARING NANOPARTICLES AND CARBON NANOTUBES 有权
标题翻译：制备纳米颗粒和碳纳米管
公开(公告)号：US20120126199A1
公开(公告)日：2012-05-24
申请号：US13299875
申请日：2011-11-18
申请人： Stephen O'Brien , Limin Huang , Brian Edward White , Samuel J. Wind
发明人： Stephen O'Brien , Limin Huang , Brian Edward White , Samuel J. Wind
IPC分类号： H01L29/12 , C23C16/26 , H01L21/04 , B32B3/10 , B05D5/00 , B05D3/02 , B82Y99/00 , B82Y40/00
CPC分类号： C01B31/0233 , B82Y30/00 , B82Y40/00 , C01B32/162 , C01B2202/02 , C01B2202/34 , C01B2202/36 , Y10T428/24802
摘要： Apparatus and methods for forming the apparatus include nanoparticles, catalyst nanoparticles, carbon nanotubes generated from catalyst nanoparticles, and methods of fabrication of such nanoparticles and carbon nanotubes.
摘要翻译：用于形成装置的装置和方法包括纳米颗粒，催化剂纳米颗粒，由催化剂纳米颗粒产生的碳纳米管，以及制备这种纳米颗粒和碳纳米管的方法。

9. 发明申请

US20090075035A1 PREPARING NANOPARTICLES AND CARBON NANOTUBES 审中-公开
标题翻译：制备纳米颗粒和碳纳米管
公开(公告)号：US20090075035A1
公开(公告)日：2009-03-19
申请号：US12246758
申请日：2008-10-07
申请人： Stephen O'Brien , Limin Huang , Brian Edward White , Samuel J. Wind
发明人： Stephen O'Brien , Limin Huang , Brian Edward White , Samuel J. Wind
IPC分类号： B32B3/10 , B05D1/32 , C23C16/26 , H01L21/283 , B05D5/12
CPC分类号： C01B32/162 , B82Y30/00 , B82Y40/00 , C01B2202/02 , C01B2202/34 , C01B2202/36 , Y10T428/24802
摘要： Apparatus and methods for forming the apparatus include nanoparticles, catalyst nanoparticles, carbon nanotubes generated from catalyst nanoparticles, and methods of fabrication of such nanoparticles and carbon nanotubes.
摘要翻译：用于形成装置的装置和方法包括纳米颗粒，催化剂纳米颗粒，由催化剂纳米颗粒产生的碳纳米管，以及制备这种纳米颗粒和碳纳米管的方法。

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