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1. 发明申请

US20090054411A1 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS 审中-公开
标题翻译： 4-ANILINOQUINOLINE-3-CARBOXAMIDES作为CSF-1R激酶抑制剂
公开(公告)号：US20090054411A1
公开(公告)日：2009-02-26
申请号：US12250314
申请日：2008-10-13
申请人： Donald Cook , Leslie Dakin , David Del Valle , Thomas Gero , David Scott , Xiaolan Zheng
发明人： Donald Cook , Leslie Dakin , David Del Valle , Thomas Gero , David Scott , Xiaolan Zheng
IPC分类号： A61K31/496 , C07D401/04 , A61K31/5377 , A61P35/00 , A61K31/551 , C07D413/04
CPC分类号： C07D215/54 , C07D401/04
摘要： The invention relates to chemical compounds of formula IA or IB: or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
摘要翻译：本发明涉及具有CSF-1R激酶抑制活性的式IA或IB化学化合物或其药学上可接受的盐，因此可用于其抗癌活性，因此可用于治疗人或动物体的方法。本发明还涉及制备所述化合物的方法，含有它们的药物组合物及其在制造用于在温血动物如人中产生抗癌作用的药物中的用途。

2. 发明申请

US20090270450A1 CHEMICAL COMPOUNDS 审中-公开
标题翻译：化学化合物
公开(公告)号：US20090270450A1
公开(公告)日：2009-10-29
申请号：US12435856
申请日：2009-05-05
申请人： Leslie Dakin , Kevin Daly , David Del Valle , Thomas Gero , Claude Afona Ogoe , David Scott , Xiaolan Zheng
发明人： Leslie Dakin , Kevin Daly , David Del Valle , Thomas Gero , Claude Afona Ogoe , David Scott , Xiaolan Zheng
IPC分类号： A61K31/47 , C07D215/44
CPC分类号： C07D215/54 , C07D401/04
摘要： The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
摘要翻译：本发明涉及具有CSF-1R激酶抑制活性的式（I）化合物或其药学上可接受的盐，因此可用于其抗癌活性，因此可用于治疗人或动物体的方法。本发明还涉及制备所述化合物的方法，含有它们的药物组合物及其在制造用于在温血动物如人中产生抗癌作用的药物中的用途。

3. 发明申请

US20080312206A1 Chemical Compounds-149 审中-公开
标题翻译：化学成分-149
公开(公告)号：US20080312206A1
公开(公告)日：2008-12-18
申请号：US12097652
申请日：2006-12-19
申请人： Brian Aquila , Donald Cook , Leslie Dakin , Stephanos Ioannidis , Paul Lyne , David Scott , Xiaolan Zheng
发明人： Brian Aquila , Donald Cook , Leslie Dakin , Stephanos Ioannidis , Paul Lyne , David Scott , Xiaolan Zheng
IPC分类号： A61K31/427 , C07D277/46 , A61K31/426 , A61P35/00 , C07D417/02
CPC分类号： C07D277/46 , C07D417/12
摘要： The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
摘要翻译：本发明涉及具有CSF 1R激酶抑制活性的化学化合物或其药学上可接受的盐，其具有CSF 1R激酶抑制活性，因此可用于其抗癌活性，因此可用于治疗人或动物体的方法。本发明还涉及制备所述化合物的方法，含有它们的药物组合物及其在制备用于在温血动物如人中产生抗癌作用的药物中的用途。

4. 发明授权

US07723337B2 3-cinnolinecarboxamide derivatives and their use for treating cancer 失效
标题翻译： 3-樟脑甲酰胺衍生物及其用于治疗癌症的用途
公开(公告)号：US07723337B2
公开(公告)日：2010-05-25
申请号：US12210588
申请日：2008-09-15
申请人： Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
发明人： Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
IPC分类号： A01N43/58 , A01N43/60 , A61K31/50 , A61K31/495 , A61K31/4965 , C07D237/26 , C07D487/00 , C07D237/28 , C07D241/04 , C07D295/00
CPC分类号： C07D237/28
摘要： The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
摘要翻译：本发明涉及具有CSF-1R激酶抑制活性的式（I）化合物或其药学上可接受的盐，因此可用于其抗癌活性，因此可用于治疗人或动物体的方法。本发明还涉及制备所述化合物的方法，含有它们的药物组合物及其在制造用于在温血动物如人中产生抗癌作用的药物中的用途。

5. 发明申请

US20110098283A1 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER 审中-公开
公开(公告)号：US20110098283A1
公开(公告)日：2011-04-28
申请号：US12781277
申请日：2010-05-17
申请人： Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
发明人： Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
IPC分类号： A61K31/502 , C07D237/28 , C07D401/10 , C07D403/10 , C07D413/10 , A61K31/55 , A61K31/5377 , A61P35/00 , C12N9/99
CPC分类号： C07D237/28
摘要： The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
摘要翻译：本发明涉及具有CSF-1R激酶抑制活性的式（I）化合物或其药学上可接受的盐，因此可用于其抗癌活性，因此可用于治疗人或动物体的方法。本发明还涉及制备所述化合物的方法，含有它们的药物组合物及其在制造用于在温血动物如人中产生抗癌作用的药物中的用途。

6. 发明申请

US20090012084A1 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER 失效
公开(公告)号：US20090012084A1
公开(公告)日：2009-01-08
申请号：US12210588
申请日：2008-09-15
申请人： Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
发明人： Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
IPC分类号： A61K31/502 , C07D237/28 , A61K31/5377 , A61P35/00 , C07D413/02
CPC分类号： C07D237/28
摘要： The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
摘要翻译：本发明涉及具有CSF-1R激酶抑制活性的式（I）化合物或其药学上可接受的盐，因此可用于其抗癌活性，因此可用于治疗人或动物体的方法。本发明还涉及制备所述化合物的方法，含有它们的药物组合物及其在制造用于在温血动物如人中产生抗癌作用的药物中的用途。

7. 发明申请

US20160367202A1 Systems and Methods for Wearable Sensor Techniques 审中-公开
标题翻译：可穿戴传感器技术的系统和方法
公开(公告)号：US20160367202A1
公开(公告)日：2016-12-22
申请号：US15074950
申请日：2016-03-18
申请人： Abraham Carter , David Scott , Ehsan Azarnasab
发明人： Abraham Carter , David Scott , Ehsan Azarnasab
IPC分类号： A61B5/00 , A61B5/024 , A61B5/145 , A61B5/08 , A61B5/091 , A61B5/03 , A61B5/11 , A61B5/1455
CPC分类号： A61B5/7289 , A61B5/0022 , A61B5/0024 , A61B5/02 , A61B5/02416 , A61B5/03 , A61B5/0816 , A61B5/091 , A61B5/1118 , A61B5/14532 , A61B5/14551 , A61B5/4806 , A61B5/4809 , A61B5/4812 , A61B5/4815 , A61B5/6824 , A61B5/6829 , A61B5/7246 , A61B5/742 , A61B5/746 , A61B2562/0219 , G06Q50/22 , H04M1/7253
摘要： Aspects of the present invention relate to analysis of physiological data sequences and activity data recorded while a user participates in various activities. Some aspects relate to alert or messaging system and methods whereby messages are automatically generated when a condition in the physiological or activity data is satisfied. Messages may be automatically formatted with physiological and/or activity data as well as other fields and content. Each message condition may be related to a unique recipient list and message content template.
摘要翻译：本发明的方面涉及在用户参与各种活动时记录的生理数据序列和活动数据的分析。一些方面涉及警报或消息传递系统和方法，从而当满足生理或活动数据中的条件时自动生成消息。消息可以使用生理和/或活动数据以及其他字段和内容自动格式化。每个消息条件可以与唯一的接收者列表和消息内容模板相关。

8. 发明申请

US20160357940A1 Systems and Methods for Connected Dispensing and Storage 审中-公开
标题翻译：连接分配和存储的系统和方法
公开(公告)号：US20160357940A1
公开(公告)日：2016-12-08
申请号：US15065339
申请日：2016-03-09
申请人： Abraham Carter , David Scott
发明人： Abraham Carter , David Scott
IPC分类号： G06F19/00 , A61J7/00 , B65D83/04 , H04B1/3827 , H04W4/00
CPC分类号： G06F19/3462 , A61J1/065 , A61J1/1418 , A61J1/1425 , A61J1/1437 , A61J1/18 , A61J7/0076 , A61J7/0409 , A61J2200/72 , A61J2200/74 , A61J2205/60 , B65D83/0409 , H04B1/385 , H04W4/80
摘要： Aspects of the present invention relate to a container for selective dispensing of a contained substance. Some aspects relate to wireless communication connections for communicating container programming data and notifications to a user or third parties. Some aspects relate to selective operation related to the proximity of a wearable component or related to a user's physiological parameters.
摘要翻译：本发明的方面涉及用于选择性分配所含物质的容器。一些方面涉及用于将容器编程数据和通知传送给用户或第三方的无线通信连接。一些方面涉及与可穿戴组件的接近度或与用户的生理参数有关的选择性操作。

10. 发明申请

US20120141352A1 SYSTEM AND METHOD FOR SEPARATING HIGH MOLECULAR WEIGHT GASES FROM A COMBUSTION SOURCE 失效
标题翻译：从燃烧源分离高分子量气体的系统和方法
公开(公告)号：US20120141352A1
公开(公告)日：2012-06-07
申请号：US13314110
申请日：2011-12-07
申请人： Jerry Lang , David Scott
发明人： Jerry Lang , David Scott
IPC分类号： C01D7/07 , B01D53/30 , B01D53/74 , B01D53/24
CPC分类号： C01D7/07 , B01D53/24 , B01D53/62 , B01D2251/304 , B01D2257/504 , B01D2258/0283 , Y02C10/04 , Y02P20/152
摘要： High molecular weight (HMW) gases are separated from an exhaust gas of a combustion source using a blower and an interior vent within the exhaust stack. The interior vent includes a vent wall having a top portion attached to the interior surface of the exhaust stack along the entire inner perimeter of the exhaust stack and a lower portion that extends downward into the exhaust stack to form an annular space or gap between the vent wall and the interior surface of the exhaust stack, and at least one opening in the interior surface of the exhaust stack between the top and bottom portions of the vent wall. The blower creates a tangential flow of the exhaust gas with sufficient centrifugal force to concentrate substantially all of the HMW gases along the inner surface of the exhaust stack. A transfer pipe removes the HMW gases from the interior vent.
摘要翻译：使用鼓风机和排气叠层内的内部通风口将高分子量（HMW）气体与燃烧源的废气分离。内部排气口包括排气壁，排气壁具有沿着排气叠层的整个内周边连接到排气叠层的内表面的顶部部分，以及向下延伸到排气叠层中的下部，以在排气口之间形成环形空间或间隙壁和排气叠层的内表面，以及排气叠层的内表面中至少一个开口，其位于排气壁的顶部和底部之间。鼓风机以足够的离心力产生废气的切向流，以基本上将所有的HMW气体沿着排气叠层的内表面进行浓缩。输送管从内部通风口去除HMW气体。

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