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1. 发明授权

US09183626B2 Systems and methods for accelerated arterial spin labeling using compressed sensing 有权
标题翻译：使用压缩感应加速动脉自旋标记的系统和方法
公开(公告)号：US09183626B2
公开(公告)日：2015-11-10
申请号：US13867325
申请日：2013-04-22
申请人： Li Zhao , Xiao Chen , Samuel W. Fielden , Frederick H. Epstein , John P. Mugler, III , Manal Nicolas-Jilwan , Max Wintermark , Craig H. Meyer
发明人： Li Zhao , Xiao Chen , Samuel W. Fielden , Frederick H. Epstein , John P. Mugler, III , Manal Nicolas-Jilwan , Max Wintermark , Craig H. Meyer
IPC分类号： G06K9/00 , G06T7/00 , G01R33/563 , A61B5/05 , G01R33/561
CPC分类号： G06T7/0012 , G01R33/4824 , G01R33/5611 , G01R33/56366 , G06K9/6232 , G06T11/005 , G06T2207/10088 , G06T2207/30104 , G06T2211/412 , G06T2211/424
摘要： Systems and methods for accelerated arterial spin labeling (ASL) using compressed sensing are disclosed. In one aspect, in accordance with one example embodiment, a method includes acquiring magnetic resonance data associated with an area of interest of a subject, wherein the area of interest corresponds to one or more physiological activities of the subject. The method also includes performing image reconstruction using temporally constrained compressed sensing reconstruction on at least a portion of the acquired magnetic resonance data, wherein acquiring the magnetic resonance data includes receiving data associated with ASL of the area of interest of the subject.
摘要翻译：公开了使用压缩感测加速动脉自旋标记（ASL）的系统和方法。在一个方面，根据一个示例性实施例，一种方法包括获取与受试者的感兴趣区域相关联的磁共振数据，其中感兴趣区域对应于受试者的一个或多个生理活动。该方法还包括在所获取的磁共振数据的至少一部分上使用时间上受限的压缩感测重构来执行图像重建，其中获取磁共振数据包括接收与被摄体的感兴趣区域的ASL相关联的数据。

2. 发明申请

US20130315461A1 SYSTEMS AND METHODS FOR ACCELERATED ARTERIAL SPIN LABELING USING COMPRESSED SENSING 有权
标题翻译：使用压缩感应加速型旋转标签的系统和方法
公开(公告)号：US20130315461A1
公开(公告)日：2013-11-28
申请号：US13867325
申请日：2013-04-22
申请人： Li Zhao , Xiao Chen , Samuel W. Fielden , Frederick H. Epstein , John P. Mugler, III , Manal Nicolas-Jilwan , Max Wintermark , Craig H. Meyer
发明人： Li Zhao , Xiao Chen , Samuel W. Fielden , Frederick H. Epstein , John P. Mugler, III , Manal Nicolas-Jilwan , Max Wintermark , Craig H. Meyer
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G01R33/4824 , G01R33/5611 , G01R33/56366 , G06K9/6232 , G06T11/005 , G06T2207/10088 , G06T2207/30104 , G06T2211/412 , G06T2211/424
摘要： Systems and methods for accelerated arterial spin labeling (ASL) using compressed sensing are disclosed. In one aspect, in accordance with one example embodiment, a method includes acquiring magnetic resonance data associated with an area of interest of a subject, wherein the area of interest corresponds to one or more physiological activities of the subject. The method also includes performing image reconstruction using temporally constrained compressed sensing reconstruction on at least a portion of the acquired magnetic resonance data, wherein acquiring the magnetic resonance data includes receiving data associated with ASL of the area of interest of the subject.
摘要翻译：公开了使用压缩感测加速动脉自旋标记（ASL）的系统和方法。在一个方面，根据一个示例性实施例，一种方法包括获取与受试者的感兴趣区域相关联的磁共振数据，其中感兴趣区域对应于受试者的一个或多个生理活动。该方法还包括在所获取的磁共振数据的至少一部分上使用时间上受限的压缩感测重构来执行图像重建，其中获取磁共振数据包括接收与被摄体的感兴趣区域的ASL相关联的数据。

3. 发明申请

US20190251755A1 INTERACTIVE VOXEL MANIPULATION IN VOLUMETRIC MEDICAL IMAGING FOR VIRTUAL MOTION, DEFORMABLE TISSUE, AND VIRTUAL RADIOLOGICAL DISSECTION 审中-公开
公开(公告)号：US20190251755A1
公开(公告)日：2019-08-15
申请号：US16195251
申请日：2018-11-19
申请人： David Byron Douglas , Robert E Douglas , Kathleen M Douglas , Max Wintermark
发明人： David Byron Douglas , Robert E Douglas , Kathleen M Douglas , Max Wintermark
IPC分类号： G06T19/20 , G06T15/08 , G06T13/00 , A61B34/10
CPC分类号： G06T19/20 , A61B34/10 , A61B2034/104 , A61B2034/105 , G06T13/00 , G06T15/08 , G06T2200/24 , G06T2210/41 , G06T2219/008 , G06T2219/2012 , G06T2219/2016 , G06T2219/2021
摘要： A simulation is performed by assigning tissue type properties to voxels of a medical image and manipulating the voxels based on the assigned tissue type properties and an input that prompts voxel manipulation. Voxels may also be created and eliminated in response to the input. Tissue type properties may include elasticity, ductility, hardness, density, and thermal conductivity. Manipulation may include changing at least one of voxel size, location, orientation, shape, color, grayscale, and tissue type property value. The input may include insertion of a virtual volume-subtending surgical or anatomic object. Simulations may include virtual motion, deformation of tissue, and radiological dissection for pre-operative planning.

4. 发明授权

US06792302B2 Method and apparatus for determining treatment for stroke 有权
标题翻译：用于确定中风治疗的方法和装置
公开(公告)号：US06792302B2
公开(公告)日：2004-09-14
申请号：US09947058
申请日：2001-09-04
申请人： Max Wintermark , Jean-Philippe Thiran , Refo Antoine Meuli
发明人： Max Wintermark , Jean-Philippe Thiran , Refo Antoine Meuli
IPC分类号： A61B505
CPC分类号： A61B5/0275 , A61B5/4064 , A61B5/4076 , A61B5/412 , A61B6/00 , A61B6/481 , A61B6/504 , A61B6/507
摘要： A method and apparatus for evaluating acute stroke patients and for determining whether a stroke patient will benefit from the use of thrombolysis therapy includes obtaining measurements of the cerebral blood flow and cerebral blood volume of the brain of a stroke patient, determining ischemic areas of the brain where the ischemic areas comprise the measurements of cerebral blood flow which are less than a first value and creating a penumbra-infarct map of the ischemic areas of the brain using the measurements. The infarct area corresponds to the area of the brain where cerebral blood volume is less than a second value. The penumbra area corresponds to the area of the brain where cerebral blood volume is greater than this second value. The method also includes determining a ratio of penumbra size to the total of penumbra size and infarct size. When the ratio is greater than a predetermined value, the stroke patient is a candidate for thrombolysis therapy.
摘要翻译：用于评估急性中风患者和用于确定中风患者是否将从使用溶栓治疗中获益的方法和装置包括获得卒中患者的脑的脑血流量和脑血容量的测量值，确定脑的缺血区域其中缺血区域包括小于第一值的脑血流量测量值，并使用测量值产生脑缺血区域的半暗带梗塞图。梗塞区域对应于脑血容量小于第二值的脑区域。半影区域对应于大脑的脑区域大于此第二值。该方法还包括确定半影大小与半暗影大小和梗塞面积的总和的比率。当比率大于预定值时，中风患者是溶栓治疗的候选者。

5. 发明申请

US20120288180A1 FUNCTIONAL IMAGING 有权
标题翻译：功能成像
公开(公告)号：US20120288180A1
公开(公告)日：2012-11-15
申请号：US13503925
申请日：2010-10-14
申请人： Joerg Bredno , Max Wintermark
发明人： Joerg Bredno , Max Wintermark
IPC分类号： G06K9/46
CPC分类号： A61B6/5217 , A61B6/032 , A61B6/481 , A61B6/486 , A61B6/501 , A61B6/507 , G01R33/5601 , G01R33/56366
摘要： A method includes determining, via a processor, functional information about tissue of interest in image data for a functional image acquisition based on reference information generated based on non-tissue of interest.
摘要翻译：一种方法包括：基于基于非感兴趣组织生成的参考信息，经由处理器确定关于功能图像获取的图像数据中的感兴趣组织的功能信息。

6. 发明申请

US20120238888A1 COLLATERAL BLOOD FLOW ASSESSMENT 有权
标题翻译：阴道血流量评估
公开(公告)号：US20120238888A1
公开(公告)日：2012-09-20
申请号：US13509804
申请日：2010-11-18
申请人： Joerg Bredno , Max Wintermark
发明人： Joerg Bredno , Max Wintermark
IPC分类号： A61B5/026
CPC分类号： A61B6/481 , A61B5/02028 , A61B6/507 , A61B8/06 , G01R33/56366
摘要： A method includes obtaining both first inflow and first perfusion metrics for non-healthy tissue of interest, obtaining both second inflow and second perfusion metrics for healthy tissue of interest, and concurrently presenting both the first flow and perfusion metrics for the non-healthy tissue of interest and both the second flow and perfusion metrics for the healthy tissue of interest.
摘要翻译：一种方法包括获得针对所关注的非健康组织的第一流入和第一灌注度量，获得所述感兴趣的健康组织的第二流入和第二灌注度量，并同时呈现所述非健康组织的第一流量和灌注度量兴趣以及感兴趣的健康组织的第二流量和灌注指标。

7. 发明授权

US07580737B2 Method and apparatus for determining treatment for stroke 有权
标题翻译：用于确定中风治疗的方法和装置
公开(公告)号：US07580737B2
公开(公告)日：2009-08-25
申请号：US10468432
申请日：2002-02-21
申请人： Max Wintermark , Jean-Philippe Thiran , Reto Antoine Meuli
发明人： Max Wintermark , Jean-Philippe Thiran , Reto Antoine Meuli
IPC分类号： A61B5/05
CPC分类号： A61B5/0275 , A61B5/4064 , A61B5/4076 , A61B5/412 , A61B6/00 , A61B6/481 , A61B6/504 , A61B6/507
摘要： A method and apparatus for evaluating acute stroke patients and for determining whether a stroke patient will benefit from the use of thrombolysis therapy includes obtaining measurements of the cerebral blood flow and cerebral blood volume of the brain of a stroke patient, determining ischemic areas of the brain where the ischemic areas comprise the measurements of cerebral blood flow which are less than a first value and creating a penumbra-infarct map of the ischemic areas of the brain using the measurements. The infarct area corresponds to the area of the brain where cerebral blood volume is less than a second value. The penumbra area corresponds to the area of the brain where cerebral blood volume is greater than this second dvalue. The method also includes determining a ratio of penumbra size to the total of penumbra size and infarct size. When the ratio is greater than a predetermined value, the stroke patient is a candidate for thrombolysis therapy.
摘要翻译：用于评估急性中风患者和用于确定中风患者是否将从使用溶栓治疗中获益的方法和装置包括获得卒中患者的脑的脑血流量和脑血容量的测量值，确定脑的缺血区域其中缺血区域包括小于第一值的脑血流量测量值，并使用测量值产生脑缺血区域的半暗带梗塞图。梗塞区域对应于脑血容量小于第二值的脑区域。半影区域对应于大脑的脑区域大于此第二d值。该方法还包括确定半影大小与半暗影大小和梗塞面积的总和的比率。当比率大于预定值时，中风患者是溶栓治疗的候选者。

8. 发明授权

US09125616B2 Collateral blood flow assessment 有权
标题翻译：侧支血流评估
公开(公告)号：US09125616B2
公开(公告)日：2015-09-08
申请号：US13509804
申请日：2010-11-18
申请人： Joerg Bredno , Max Wintermark
发明人： Joerg Bredno , Max Wintermark
IPC分类号： A61B5/02 , A61B6/00 , A61B8/06 , G01R33/563
CPC分类号： A61B6/481 , A61B5/02028 , A61B6/507 , A61B8/06 , G01R33/56366
摘要： A method includes obtaining both first inflow and first perfusion metrics for non-healthy tissue of interest, obtaining both second inflow and second perfusion metrics for healthy tissue of interest, and concurrently presenting both the first flow and perfusion metrics for the non-healthy tissue of interest and both the second flow and perfusion metrics for the healthy tissue of interest.
摘要翻译：一种方法包括获得针对所关注的非健康组织的第一流入和第一灌注度量，获得所述感兴趣的健康组织的第二流入和第二灌注度量，并同时呈现所述非健康组织的第一流量和灌注度量兴趣以及感兴趣的健康组织的第二流量和灌注指标。

9. 发明授权

US08660333B2 Functional imaging 有权
标题翻译：功能成像
公开(公告)号：US08660333B2
公开(公告)日：2014-02-25
申请号：US13503925
申请日：2010-10-14
申请人： Joerg Bredno , Max Wintermark
发明人： Joerg Bredno , Max Wintermark
IPC分类号： G06K9/00
CPC分类号： A61B6/5217 , A61B6/032 , A61B6/481 , A61B6/486 , A61B6/501 , A61B6/507 , G01R33/5601 , G01R33/56366
摘要： A method includes determining, via a processor, functional information about tissue of interest in image data for a functional image acquisition based on reference information generated based on non-tissue of interest.
摘要翻译：一种方法包括：基于基于非感兴趣组织生成的参考信息，经由处理器确定关于功能图像获取的图像数据中的感兴趣组织的功能信息。

10. 发明申请

US20110211742A1 PERFUSION IMAGING 有权
标题翻译：灌注成像
公开(公告)号：US20110211742A1
公开(公告)日：2011-09-01
申请号：US13062227
申请日：2009-09-10
申请人： Joerg Bredno , Max Wintermark
发明人： Joerg Bredno , Max Wintermark
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/032 , A61B6/481 , A61B6/507 , G06F19/00 , G06F19/321 , G16H40/63 , G16H50/50
摘要： A system includes a perfusion information determiner (124) that determines perfusion information based on a combination of pre-perfusion scan image data and perfusion scan image data.
摘要翻译：一种系统包括基于灌注前扫描图像数据和灌注扫描图像数据的组合来确定灌注信息的灌注信息确定器（124）。

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