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1. 发明申请

US20110207751A1 HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS 审中-公开
标题翻译：杂环化合物和作为反应剂的用途
公开(公告)号：US20110207751A1
公开(公告)日：2011-08-25
申请号：US13031134
申请日：2011-02-18
申请人： Long Mao , Xiaobo Wang , Xiao Xu , Li Zhao , Jia Liu
发明人： Long Mao , Xiaobo Wang , Xiao Xu , Li Zhao , Jia Liu
IPC分类号： A61K31/519 , C07D487/04 , A61P35/00 , A61P35/02 , A61K31/429 , C07D513/04 , A61K31/4439
CPC分类号： C07D471/04 , C07D513/04
摘要： Novel compounds having a fused bicyclic heteroaromatic ring system substituted with a thiazole ring are disclosed. The compounds inhibit growth of a variety of types of cancer cells, and are thus useful for treating cancer. Efficacy of these compounds is demonstrated with a system for monitoring cell growth/migration, which shows they are potent inhibitors of growth and/or migration of cancer cells. In addition, compounds of the invention were shown to stop growth of tumors in vivo, and to reduce the size of tumors in vivo. Compositions comprising these compounds, and methods to use these compounds and compositions for treatment of cancers, are disclosed.
摘要翻译：公开了具有被噻唑环取代的稠合双环杂芳环体系的新型化合物。这些化合物抑制多种类型的癌细胞的生长，因此可用于治疗癌症。通过用于监测细胞生长/迁移的系统来证明这些化合物的功效，这表明它们是癌细胞的生长和/或迁移的有效抑制剂。此外，本发明的化合物被证明可以在体内停止肿瘤生长，并减少体内肿瘤的大小。公开了包含这些化合物的组合物，以及使用这些化合物和用于治疗癌症的组合物的方法。

2. 发明授权

US10508279B2 Recombinant Escherichia coli for high efficiency production of fructosylated chondroitin and method for making thereof 有权
公开(公告)号：US10508279B2
公开(公告)日：2019-12-17
申请号：US15891564
申请日：2018-02-08
申请人： Jing Wu , Quan Zhang , Liming Liu , Xiulai Chen , Jia Liu , Qiuling Luo
发明人： Jing Wu , Quan Zhang , Liming Liu , Xiulai Chen , Jia Liu , Qiuling Luo
IPC分类号： C12N1/20 , C12N15/70 , C12N9/10 , C12N9/90 , C12P19/24 , C12P19/26
摘要： The present invention relates to the field of biotechnology engineering. It provides a recombinant Escherichia coli that can produce fructosylated chondroitin with high yields and the method for constructing the recombinant strain. The present invention discloses a method for constructing an expression plasmid pETM6R1-RBS-glmM-GGGS-glmS that contains a glmM and a glmS gene under regulation of ribosome binding sites. The recombinant plasmid was transformed into E. coli K4 to obtain a recombinant E. coli strain ZQ33 that can produce fructosylated chondroitin up to 3.99 g·L−1 by fed-batch fermentation in a 5-L fermentor, which was increased by 108.90% compared to that of the wild type strain.

3. 发明授权

US09344204B2 Method, apparatus, and computer program product for adaptive relaying data distribution in wireless networks 有权
标题翻译：用于无线网络中自适应中继数据分发的方法，装置和计算机程序产品
公开(公告)号：US09344204B2
公开(公告)日：2016-05-17
申请号：US14381688
申请日：2012-04-05
申请人： Canfeng Chen , Jia Liu , Yongguang Guo , Mika Kasslin
发明人： Canfeng Chen , Jia Liu , Yongguang Guo , Mika Kasslin
IPC分类号： H04H20/08 , H04H20/71 , H04W40/22
CPC分类号： H04H20/08 , H04H20/71 , H04W40/22
摘要： Method, apparatus, and computer program product example embodiments enable data distribution in wireless communication networks. In example embodiments, a method comprises receiving a wireless broadcast message including a message ID and an associated distributor address; buffering the received wireless broadcast message and starting an observation window timer for the message if the message ID of the received wireless broadcast message is not stored in a database of message IDs and associated distributor addresses for previously received wireless broadcast messages; calculating a relaying probability for the received wireless broadcast message, based on a number of distributor address entries associated with the message ID in the database, the entries resulting from receiving other wireless broadcast messages having the same message ID during the observation window; transmitting the buffered message following termination of the observation window, based on the calculated relaying probability; and starting a cooling window timer upon termination of the observation window and removing all records containing the message ID from the database following termination of the cooling window.
摘要翻译：方法，装置和计算机程序产品示例实施例使能无线通信网络中的数据分发。在示例实施例中，一种方法包括接收包括消息ID和相关联的分配器地址的无线广播消息; 如果所接收的无线广播消息的消息ID未被存储在用于先前接收到的无线广播消息的消息ID和相关联的分配器地址的数据库中，则缓存所接收的无线广播消息并启动该消息的观察窗口定时器; 基于与数据库中的消息ID相关联的分配器地址条目的数量来计算所接收的无线广播消息的中继概率，在观察窗口期间从接收到具有相同消息ID的其他无线广播消息导致的条目; 基于所计算的中继概率，在观察窗口终止后发送缓冲消息; 并在观察窗口终止后启动冷却窗口计时器，并在冷却窗口终止后从数据库中删除包含消息ID的所有记录。

4. 发明授权

US09217423B2 Energy storage system using supercritical air 有权
标题翻译：储能系统采用超临界空气
公开(公告)号：US09217423B2
公开(公告)日：2015-12-22
申请号：US13508019
申请日：2010-08-31
申请人： Haisheng Chen , Chunqing Tan , Jia Liu , Yujie Xu
发明人： Haisheng Chen , Chunqing Tan , Jia Liu , Yujie Xu
IPC分类号： F15B1/027 , F03G7/06 , F01K3/00 , F25J3/04 , F25J1/00 , F25J1/02
CPC分类号： F03G7/06 , F01K3/004 , F01K5/02 , F01K7/22 , F25J1/0012 , F25J1/0037 , F25J1/0045 , F25J1/0228 , F25J1/0251 , F25J3/04018 , F25J3/04054 , F25J3/04084 , F25J3/04187 , F25J3/04193 , F25J3/04309 , F25J3/044 , F25J3/04581 , F25J3/04842 , F25J2205/24 , F25J2230/04 , F25J2230/08 , F25J2230/30 , F25J2240/10 , F25J2240/90 , F25J2245/90 , Y02E60/15
摘要： Disclosed is an energy storage system using supercritical air, comprising a compressor unit, a heat exchanger and storage device, a cold exchanger and storage device, a cryogenic tank, a throttling valve, at least one cryogenic pump, an expander unit, a generator, and a driver unit. There are several advantages of this invention, including high energy density, high efficiency, no storage cycle and geographical conditions restriction, easy implementation with all kinds of power stations, environment friendliness and capability of recycling low to medium temperature waste heat and so on.
摘要翻译：公开了一种使用超临界空气的能量存储系统，包括压缩机单元，热交换器和存储装置，冷交换器和存储装置，低温罐，节流阀，至少一个低温泵，膨胀器单元，发电机，和驱动单元。本发明有几个优点，包括高能量密度，高效率，无储存循环和地理条件限制，易于实施各种发电站，环境友好和回收中低温余热等能力。

5. 发明授权

US09187333B2 Carbon activation in a microwave fluidized bed process 有权
标题翻译：微波流化床工艺中的碳活化
公开(公告)号：US09187333B2
公开(公告)日：2015-11-17
申请号：US13590682
申请日：2012-08-21
申请人： Kishor Purushottam Gadkaree , Andrew Fleitz Husted , Naveen Kekre , Jia Liu
发明人： Kishor Purushottam Gadkaree , Andrew Fleitz Husted , Naveen Kekre , Jia Liu
IPC分类号： C01B31/08 , C01B31/10
CPC分类号： C01B31/10 , C01B32/336 , C01B32/366
摘要： A method for forming activated carbon from carbon feedstock involves forming particles of the carbon feedstock, introducing the carbon feedstock particles into a microwave reaction chamber and forming a fluidized bed of the particles within the chamber, introducing steam into the reaction chamber, and introducing microwaves into the reaction chamber to heat the particles using microwave energy and react the heated particles with the steam to form activated carbon.
摘要翻译：从碳原料形成活性炭的方法包括形成碳原料的颗粒，将碳原料颗粒引入微波反应室，并在室内形成颗粒的流化床，将蒸汽引入反应室，并将微波引入反应室用微波能加热颗粒，并使加热的颗粒与蒸汽反应形成活性炭。

6. 发明授权

US08942015B2 Control device and control method during bypassing of power units 有权
标题翻译：旁路动力装置时的控制装置及控制方法
公开(公告)号：US08942015B2
公开(公告)日：2015-01-27
申请号：US13619416
申请日：2012-09-14
申请人： Jia Liu , Yong-Qiang Lang , Yu-Yang Mao
发明人： Jia Liu , Yong-Qiang Lang , Yu-Yang Mao
IPC分类号： H02M7/49 , H02M1/32
CPC分类号： H02M7/49 , H02M1/32 , H02M2001/325
摘要： A control device and a control method during bypassing of power units are provided. The method includes: detecting a first three-phase output electrical signal; calculating a first positive sequence component and a first negative sequence component of the first three-phase output electrical signal; providing a given positive sequence component and a given negative sequence component so as to respectively perform the closed-loop compensation on the first positive sequence component and the first negative sequence component, thereby outputting a second positive sequence component and a second negative sequence component; superimposing the second positive sequence component and the second negative sequence component; and outputting a second three-phase output electrical signal in a preset way.
摘要翻译：提供了在旁路功率单元期间的控制装置和控制方法。该方法包括：检测第一三相输出电信号; 计算第一三相输出电信号的第一正序分量和第一负序分量; 提供给定的正序分量和给定的负序分量，以分别对第一正序分量和第一负序分量执行闭环补偿，从而输出第二正序分量和第二负序分量; 叠加第二正序分量和第二负序分量; 并以预设的方式输出第二三相输出电信号。

7. 发明授权

US08935767B2 Overlay human interactive proof system and techniques 有权
标题翻译：覆盖人类互动证明系统和技术
公开(公告)号：US08935767B2
公开(公告)日：2015-01-13
申请号：US12780013
申请日：2010-05-14
申请人： Weisheng Li , Bin Zhu , Ning Xu , Jia Liu
发明人： Weisheng Li , Bin Zhu , Ning Xu , Jia Liu
IPC分类号： H04L29/00 , G06F9/44 , G06F21/36 , H04L9/32
CPC分类号： G06F9/44 , G06F21/36 , G06F2221/2133 , H04L9/32
摘要： The overlay human interactive proof system (“OHIPS”) and techniques described herein operate in conjunction with any known or later developed computer-based applications or services to provide secure access to resources by reliably differentiating between human and non-human users. Humans have a generally superior ability to differentiate misaligned characters or objects from correctly aligned ones. As such, the OHIP splits an image including one or more visual objects into two or more partial images to form a HIP. The partial images may also be further split into groups of sub-partial images, and/or the partial images (or the sub-partial images) may be moved, so that at any given alignment position, a user can recognize only some visual objects. A user is instructed to reassemble the partial images at one or more predetermined alignment positions using a GUI, and the user is asked to identify information regarding one or more visible objects.
摘要翻译：覆盖人类交互式证明系统（“OHIPS”）和本文所描述的技术与任何已知或未来开发的基于计算机的应用或服务相结合，通过可靠地区分人和非人类用户来提供对资源的安全访问。人类具有一般优越的能力来区分不正确的字符或对象与正确对齐的字符或对象。因此，OHIP将包括一个或多个可视对象的图像分割成两个或更多个部分图像以形成HIP。部分图像还可以进一步分割成一组子部分图像，和/或部分图像（或子部分图像）可以被移动，使得在任何给定的对准位置，用户只能识别一些视觉对象。指示用户使用GUI重新组装在一个或多个预定对准位置处的部分图像，并且要求用户识别关于一个或多个可见对象的信息。

8. 发明授权

US08893012B1 Visual indicator based on relative rating of content item 有权
标题翻译：基于内容项的相对评级的视觉指标
公开(公告)号：US08893012B1
公开(公告)日：2014-11-18
申请号：US13654241
申请日：2012-10-17
申请人： Xincheng Zhang , Jia Liu , Dongmin Zhang , Michael P. Bachman
发明人： Xincheng Zhang , Jia Liu , Dongmin Zhang , Michael P. Bachman
IPC分类号： G06Q30/02
CPC分类号： G06Q30/0277 , G06Q30/0243 , G06Q30/0245 , G06Q30/0282
摘要： A popularity score or rating may be provided for a third-party content item. The popularity score may be compared with an average score of similar genre third-party content items to determine a relationship of the popularity score relative to the average score of similar genre third-party content items. A popularity or other visual indicator may be provided proximate to the third-party content item to provide a visual indication of the relationship. The popularity indicator may include a bar or a plurality of symbols in some implementations.
摘要翻译：可以为第三方内容项目提供流行度得分或评级。流行度得分可以与相似类型的第三方内容项目的平均分数进行比较，以确定人气分数相对于类似类型的第三方内容项目的平均分数的关系。可以在第三方内容项目附近提供流行度或其他视觉指示符，以提供关系的视觉指示。在一些实现中，流行指标可以包括条形码或多个符号。

9. 发明授权

US08856131B1 Computer networked selecting of consumer interests 有权
标题翻译：计算机联网选择消费者利益
公开(公告)号：US08856131B1
公开(公告)日：2014-10-07
申请号：US13523616
申请日：2012-06-14
申请人： Jia Liu , Yijian Bai , Manojav Patil , Deepak Ravichandran , Sittichai Jiampojamarn , Shankar Ponnekanti
发明人： Jia Liu , Yijian Bai , Manojav Patil , Deepak Ravichandran , Sittichai Jiampojamarn , Shankar Ponnekanti
IPC分类号： G06F7/04 , G06F17/30
CPC分类号： G06F17/30867 , G06Q30/02
摘要： Systems and methods of selecting consumers to receive content on a computer network are provided. A user list identifying a first plurality of users having a group of features corresponding to internet activity of the first plurality of users can be obtained at a computing device. A subgroup of features can be selected from the group of features, and a cluster of users of the first plurality of users can be identified. The users of the cluster of users can each have at least one feature of the subgroup of features. A supplemental user having a supplemental feature can be identified. A correlation between the supplemental feature and at least one feature of the subgroup of features can be determined, and an expanded user list that includes at least one of the first plurality of users and the supplemental user can be generated.
摘要翻译：提供了选择消费者在计算机网络上接收内容的系统和方法。可以在计算设备处获得识别具有与第一多个用户的互联网活动相对应的特征组的第一多个用户的用户列表。可以从特征组中选择特征的子组，并且可以识别第一多个用户的一群用户。用户群集的用户可以各自具有该特征子组的至少一个特征。可以识别具有补充特征的补充用户。可以确定补充特征与特征子组的至少一个特征之间的相关性，并且可以生成包括第一多个用户和补充用户中的至少一个的扩展用户列表。

10. 发明授权

US08405955B2 High performance electrodes for EDLCS 有权
标题翻译： EDLCS高性能电极
公开(公告)号：US08405955B2
公开(公告)日：2013-03-26
申请号：US12724451
申请日：2010-03-16
申请人： Kishor Purushottam Gadkaree , Shrisudersan Jayaraman , James Robert Lim , Jia Liu
发明人： Kishor Purushottam Gadkaree , Shrisudersan Jayaraman , James Robert Lim , Jia Liu
IPC分类号： H01G9/00
CPC分类号： H01G11/38 , H01G11/26 , H01G11/32 , Y02E60/13 , Y02T10/7022
摘要： An electric double layer capacitor composite electrode includes a current collector having opposing major surfaces, first and second conductive layers formed over respective ones of the major surfaces, and first and second carbon-based layers formed over the first and second conductive layers.
摘要翻译：电双层电容器复合电极包括具有相对的主表面的集电器，形成在主要表面的相应主表面上的第一和第二导电层，以及形成在第一和第二导电层上的第一和第二碳基层。

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