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    • 1. 发明授权
    • Multilayer materials
    • 多层材料
    • US06923978B2
    • 2005-08-02
    • US10368693
    • 2003-02-19
    • Ronald Christopher ChatelierLiming DaiHans Jörg GriesserSheng LiPaul ZientekDieter LohmannPeter Chabrecek
    • Ronald Christopher ChatelierLiming DaiHans Jörg GriesserSheng LiPaul ZientekDieter LohmannPeter Chabrecek
    • A61L27/00A61L27/34C08L101/16G02B1/04G02C7/04A61F2/00C08F8/00
    • G02B1/043A61L27/34C08L5/00
    • The invention is directed to a composite material, especially a biomedical device, e.g. an ophthalmic device, preferably a contact lens, with one or more wettable surfaces capable of holding a continuous layer of aqueous fluid thereon which composite material comprises a bulk material and a hydrophilic coating characterized in that the hydrophilic coating consists of a carbohydrate attached covalently to reactive groups at the surface of the bulk material, either directly or via functional groups of an oligofunctional compound, said oligofunctional compound in turn having functional groups being capable of reacting with said reactive groups at the surface of the bulk material and with the carbohydrate, wherein said reactive groups are either inherently (a priori) present in the bulk material or wherein said reactive groups have been attached to the surface of the bulk material by a plasma surface preparation, as well as to a process of manufacture of such a composite material.
    • 本发明涉及复合材料,特别是生物医学装置,例如, 眼科装置,优选隐形眼镜,具有能够在其上容纳水性流体的连续层的一个或多个可润湿表面,所述复合材料包括本体材料和亲水涂层,其特征在于,所述亲水性涂层由共价连接到反应性的碳水化合物 在本体材料表面的基团,直接地或通过低官能化合物的官能团,所述低官能化合物又具有能够与本体材料的表面与碳水化合物的所述反应性基团反应的官能团,其中所述 反应性基团本质上(先验地)存在于本体材料中,或者其中所述反应性基团已经通过等离子体表面制备被附着到散装材料的表面,以及制造这种复合材料的方法。