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21. 发明申请

US20230116753A1 COLLISION PROTECTION FOR A MICROSCOPE 有权
公开(公告)号：US20230116753A1
公开(公告)日：2023-04-13
申请号：US17938123
申请日：2022-10-05
申请人： Carl Zeiss Microscopy GmbH
发明人： Ingo FAHLBUSCH , Martin MUELLER , Johannes KNOBLICH
IPC分类号： G02B21/26 , G02B21/24
摘要： An apparatus for mounting an objective to a microscope structural member, and a method for operating a microscope. The apparatus for mounting an objective to a microscope structural member includes a receptacle, which is mounted or mountable to the microscope structural member, a slide-in part, which is mounted or mountable to the objective and is insertable into the receptacle where it can be brought into a locked position in which there is play between the slide-in part and the receptacle, and a tensioning unit, which, in the locked position, braces the slide-in part and the receptacle against each other in order to eliminate the play. The apparatus furthermore includes a first collision detection device, which has at least one first displacement sensor for detecting a displacement of the slide-in part and/or of the objective, in each case relative to the receptacle.

22. 发明申请

US20230111094A1 MICROSCOPE SYSTEM, IMAGING METHOD, AND IMAGING DEVICE 有权
公开(公告)号：US20230111094A1
公开(公告)日：2023-04-13
申请号：US17906363
申请日：2021-03-15
申请人： SONY GROUP CORPORATION
发明人： TAKESHI MATSUI , HIROKAZU TATSUTA , MITSUNORI UEDA , SEIJI WADA
IPC分类号： G02B21/24 , G02B21/00 , G02B21/08 , H04N23/74 , H04N23/71
摘要： A microscope system includes: a light source unit that emits linear illumination parallel to a first direction; an objective lens that condenses the linear illumination onto a measurement target region; an acquisition unit that acquires a first optical signal indicating a light intensity value of light emitted from the measurement target region by the linear illumination; and a focus control unit that controls at least one of a relative position or a relative posture of the light source unit and an imaging unit that generates the first optical signal on a basis of a light intensity distribution of the first optical signal.

23. 发明授权

US11609186B2 Systems and methods for in-operating-theatre imaging of fresh tissue resected during surgery for pathology assessment 有权
公开(公告)号：US11609186B2
公开(公告)日：2023-03-21
申请号：US16054681
申请日：2018-08-03
申请人： SamanTree Medical SA
发明人： Bastien Rachet , Davor Kosanic , Etienne Shaffer
IPC分类号： G02B21/00 , G01N21/77 , G02B21/26 , G02B21/34 , G02B21/36 , G01N21/64 , G01N33/483 , G02B21/16 , G02B21/24
摘要： The disclosed technology brings histopathology into the operating theatre, to enable real-time intra-operative digital pathology. The disclosed technology utilizes confocal imaging devices image, in the operating theatre, “optical slices” of fresh tissue—without the need to physically slice and otherwise process the resected tissue as required by frozen section analysis (FSA). The disclosed technology, in certain embodiments, includes a simple, operating-table-side digital histology scanner, with the capability of rapidly scanning all outer margins of a tissue sample (e.g., resection lump, removed tissue mass). Using point-scanning microscopy technology, the disclosed technology, in certain embodiments, precisely scans a thin “optical section” of the resected tissue, and sends the digital image to a pathologist rather than the real tissue, thereby providing the pathologist with the opportunity to analyze the tissue intra-operatively. Thus, the disclosed technology provides digital images with similar information content as FSA, but faster and without destroying the tissue sample itself.

24. 发明授权

US11598760B2 Geologic core inspection table 有权
公开(公告)号：US11598760B2
公开(公告)日：2023-03-07
申请号：US16750473
申请日：2020-01-23
申请人： Saudi Arabian Oil Company
发明人： Abdul Hafiz O. Masri , Mokhles M. Mezghani , Mustafa A. Al Ibrahim
IPC分类号： G01N33/24 , A47B9/10 , A47B9/20 , A47B13/00 , A47B37/00 , B60B33/00 , G02B21/24
摘要： A geologic core inspection table includes at least two legs, each including an extending portion for increasing the effective length of each leg, the extending portion at least partially concentrically disposed within or about the leg from which it extends; and a tabletop disposed above and coupled to the legs. The tabletop includes a top surface for receiving a core sample tray. At least one leg may be extended to a different height than at least one other leg.

25. 发明授权

US11592658B2 Adjustable digital microscope display 有权
公开(公告)号：US11592658B2
公开(公告)日：2023-02-28
申请号：US15786192
申请日：2017-10-17
申请人： Bio-Rad Laboratories, Inc.
发明人： Frank Hsiung , Kelly Kroeger , Robert Archer , Veronika Kortisova , Teresa Rubio , Amber Iraeta
IPC分类号： G02B21/36 , G02B21/24
摘要： The present invention relates in general to microscopy systems. In particular, the present invention relates to microscopes rendering digital images of samples, with the capability to digitally control the focus of the microscope system, and the software used to control the operation of the digital microscope system. Further, the present invention relates to a microscope structure that allows for compact and multi-functional use of a microscope, providing for light shielding and control with samples that require specific light wavelength characteristics, such as fluorescence, for detection and imaging. The microscope is adjustable, with a structure that can move along range(s) of motion and degree(s) of freedom to allow for ease of access to samples, shielding of samples, and manipulation of a display apparatus.

26. 发明申请

US20230057470A1 HIGH RESOLUTION MULTI-FIELD-OF-VIEW IMAGING SYSTEM 有权
公开(公告)号：US20230057470A1
公开(公告)日：2023-02-23
申请号：US17820474
申请日：2022-08-17
申请人： Onto Innovation Inc.
发明人： John A. Tejada , Ju Jin , Jian Ding
IPC分类号： G02B13/22 , G02B21/02 , G02F1/33 , G02B21/36 , H04N5/232 , G02B25/00 , G02B21/24
摘要： A multichannel tunable lens system may include a review channel with a fluidic focusing device, which can adjust the focus of the channel rapidly to mitigate environmental vibrations. The review channel may generate high resolution images with reduced blur caused by vibrations or air turbulence while increasing the operating speed of the system. The review channel may include a telescope objective and eyepiece with telecentricity to generate a real image of the pupil in the fluidic focusing device. The system may also include an inspection channel to generate lower resolution images in parallel and a focus channel to determine contour information.

27. 发明授权

US11561384B2 Method and device for adjusting the focus or determining the refractive index of a sample medium, non-volatile computer-readable storage medium and microscope 有权
$Method and device for adjusting the focus or determining the refractive index of a sample medium, non-volatile computer-readable storage medium and microscope$
公开(公告)号：US11561384B2
公开(公告)日：2023-01-24
申请号：US16955813
申请日：2018-12-21
申请人： Leica Microsystems CMS GmbH
发明人： Florian Fahrbach
IPC分类号： G01J3/02 , G02B21/24 , G01N21/41 , G02B21/00
摘要： A method for adjusting a focus of an optical system includes focusing measurement light in a sample space using an optical arrangement. The measurement light is transmitted on a sample side of the optical arrangement through at least one optical medium. The measurement light reflected by a reflector and transmitted through a further optical arrangement is detected using a detector arrangement. A working distance between the optical arrangement and the reflector is ascertained based on the measurement light detected by the detector, wherein a focus of the measurement light lies on the reflector for the working distance.

28. 发明授权

US11506876B2 Surgical optical zoom system 有权
公开(公告)号：US11506876B2
公开(公告)日：2022-11-22
申请号：US17214880
申请日：2021-03-28
申请人： Synaptive Medical Inc.
发明人： Tammy Kee-Wai Lee , William La , Paul Quevedo , Aryeh Benjamin Taub , Yusuf Bismilla , Sam Anthony Leitch , Yuri Alexander Kuzyk , Ze Shan Yao , Michael Frank Gunter Wood
IPC分类号： G02B21/00 , A61B90/20 , G02B21/36 , A61B90/25 , G02B21/02 , G02B21/24 , A61B90/00 , A61B34/20 , G06T7/246 , G06T7/73 , H04N5/225
摘要： Methods and systems for controlling a surgical microscope. Moveable optics of the surgical microscope are controlled using two sets of control parameters, to reduce jitter and image instability. Shifts in the image due to changes in temperature or due to the use of optical filter can also be compensated. Misalignment between the mechanical axis and the optical axis of the surgical microscope can also be corrected.

29. 发明申请

US20220317430A1 THREE-DIMENSIONAL VIEWING DEVICE 有权
公开(公告)号：US20220317430A1
公开(公告)日：2022-10-06
申请号：US17219953
申请日：2021-04-01
申请人： World Precision Instruments
发明人： Clifford Bredenberg , Cory Boyes , Chris Hatcher
IPC分类号： G02B21/22 , H04N5/232 , G02B21/02 , G02B21/36 , H04N13/239 , G02B30/36 , G02B21/24
摘要： A three-dimensional viewing includes a pair of digital image sensors in communication with a pair of digital displays and controlled by a pair of processors to render three-dimensional images of samples on the displays.

30. 发明申请

US20220308331A1 Microscope System 有权
公开(公告)号：US20220308331A1
公开(公告)日：2022-09-29
申请号：US17693047
申请日：2022-03-11
申请人： Hitachi High-Tech Corporation
发明人： Nobuhiko KANZAKI , Yuko OTANI
IPC分类号： G02B21/36 , H01J37/26 , H01J37/21 , G02B21/06 , G02B21/24 , G06T7/73 , G06T7/00
摘要： Regarding a microscope system, a technique capable of suitably achieving a focusing on a surface of a sample is provided. The microscope system includes an irradiation optical system (laser light source 101 or the like) that irradiates a surface of a sample 3 on a stage 104 with light from an oblique direction, an observation optical system (camera 112 or the like) that forms an image of scattered light from the surface of the sample 3, a focus mechanism (piezo stage 106 or the like) that changes a height position of focus with respect to the surface of the sample 3, and a computer system 100 that acquires an image from the observation optical system. Regarding the sample 3, the computer system acquires a first image in a first focus state and a second image in a second focus state, in which the first image and the second image have different focus heights, calculates an amount of change between a position of a first spot pattern in the first image and a position of a second spot pattern in the second image, calculates an amount of change in height of the sample 3 based on an incident angle in the oblique direction and the amount of change in position of spot pattern, and adjusts the height position of the focus by using the amount of change in sample height so as to focus on the surface of the sample 3.

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