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    • 52. 发明授权
    • Contact lenses having sensors with adjustable sensitivity
    • 隐形眼镜具有灵敏度可调的传感器
    • US09326710B1
    • 2016-05-03
    • US13623155
    • 2012-09-20
    • Verily Life Sciences LLC
    • Zenghe LiuBrian Otis
    • A61B5/02A61B5/145A61B5/00A61B3/10H05K3/46A61B5/1473H05K1/18H05K3/04
    • A61B5/14532A61B3/10A61B3/101A61B5/14546A61B5/1468A61B5/1473A61B5/6813A61B5/6821A61B2560/0223H05K1/186H05K3/048H05K3/4682
    • Apparatus and methods employing contact lenses having electrochemical sensors that have adjustable analyte-sensing sensitivity are provided. In some aspects, level of the analyte or biological substance is detected and a number of sub-electrodes of the sensor are turned on or off based on the level of the analyte or biological substance. The sensitivity of the sensor is adjusted based on the number of sub-electrodes that are turned on or off. In some aspects, the current level from the sensor is employed in determining the number of sub-electrodes to turn on or off. In one aspect, a contact lens includes: a substrate; a power component; a circuit and an adjustment circuit. The circuit can include a potentiostat; and a sensor electrically coupled to the potentiostat, and configured to sense a level of an analyte. The sensitivity of the sensor can be adjustable by the adjustment circuit.
    • 提供了使用具有可调节的分析物感测灵敏度的具有电化学传感器的隐形眼镜的装置和方法。 在一些方面,检测分析物或生物物质的水平,并且基于分析物或生物物质的水平来打开或关闭传感器的多个子电极。 基于打开或关闭的子电极的数量来调节传感器的灵敏度。 在一些方面,来自传感器的电流水平用于确定要打开或关闭的子电极的数量。 一方面,隐形眼镜包括:基底; 电源组件; 电路和调整电路。 电路可以包括恒电位仪; 以及电耦合到所述恒电位仪并且被配置为感测分析物的水平的传感器。 传感器的灵敏度可以通过调节电路调节。