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    • 63. 发明授权
    • Robust, self-assembled, biocompatible films
    • 坚固的,自组装的生物相容膜
    • US08759008B2
    • 2014-06-24
    • US12777837
    • 2010-05-11
    • Basil I. SwansonAaron S. AndersonAndrew M. DattelbaumJurgen G. Schmidt
    • Basil I. SwansonAaron S. AndersonAndrew M. DattelbaumJurgen G. Schmidt
    • G01N33/53
    • G01N33/54393G01N33/551Y10T428/31663
    • The present invention provides a composite material including a substrate having an oxide surface, and, a continuous monolayer on the oxide surface, the monolayer including a silicon atom from a trifunctional alkyl/alkenyl/alkynyl silane group that attaches to the oxide surface, an alkyl/alkenyl/alkynyl portion of at least three carbon atoms, a polyalkylene glycol spacer group, and either a reactive site (e.g., a recognition ligand) or a site resistant to non-specific binding (e.g., a methoxy or the like) at the terminus of each modified SAM. The present invention further provides a sensor element, a sensor array and a method of sensing, each employing the composite material. Patterning is also provided together with backfilling to minimize non-specific binding.
    • 本发明提供一种复合材料,其包括具有氧化物表面的基材和在氧化物表面上的连续单层,所述单层包含与氧化物表面连接的三官能烷基/烯基/炔基硅烷基团的硅原子,烷基 至少三个碳原子的链烯基/炔基部分,聚亚烷基二醇间隔基,以及反应性位点(例如,识别配体)或对非特异性结合(例如,甲氧基等)具有抗性的位点 每个修饰的SAM的末端。 本发明还提供了各自采用复合材料的传感器元件,传感器阵列和感测方法。 还提供图案化以及回填以最小化非特异性结合。
    • 64. 发明申请
    • SCALABLE AND PROGRAMMABLE COMPUTER SYSTEMS
    • 可扩展和可编程计算机系统
    • US20140149715A1
    • 2014-05-29
    • US14039303
    • 2013-09-27
    • Los Alamos National Security, LLC
    • Jeffrey Thornton Inman
    • G06F9/38
    • G06F15/17393H04L49/1507
    • Efficient, scalable, programmable, and reliable computing systems, built from a homogeneous set of relatively humble processors arranged logically or physically into a Recurrent Multi-Stage Interconnection Network (RMIN) is provided. The RMIN may include a plurality of layers, where each of the plurality of layers includes a plurality of nodes. The RMIN may also include a plurality of links configured to connect each of the plurality of layers, and a plurality of recurrent links configured to connect a plurality of nodes in a last layer of the plurality of layers to plurality nodes in a first layer of the plurality of layers. The plurality of links, together with the plurality of recurrent links, may be configured to allow data originating in any layer of the plurality of layers to pass through each of the plurality of layers without interruption.
    • 提供了从逻辑上或物理上配置为循环多阶段互连网络(RMIN)的均匀集合的相对较小的处理器构建的高效,可扩展,可编程和可靠的计算系统。 RMIN可以包括多个层,其中多个层中的每一层包括多个节点。 RMIN还可以包括被配置为连接多个层中的每一层的多个链路,以及被配置为将多个层的最后一层中的多个节点连接到第一层中的多个节点的多个循环链路 多层。 多个链接以及多个循环链接可以被配置为允许源自多个层的任何层的数据不间断地穿过多个层中的每一个。
    • 67. 发明授权
    • Method of fabricating free-form, high-aspect ratio components for high-current, high-speed microelectronics
    • 制造高电流,高速微电子学自由形式,高纵横比组分的方法
    • US08669164B2
    • 2014-03-11
    • US12753682
    • 2010-04-02
    • James L. MaxwellChris R. RoseMarcie R. BlackRobert W. Springer
    • James L. MaxwellChris R. RoseMarcie R. BlackRobert W. Springer
    • H01L21/205H01L21/365C01B33/02C01B35/00
    • H01L21/205B81C1/0019H01L21/02521H01L21/02532H01L21/02573H01L21/0259H01L21/0262H01L21/02636H01L21/28556H01L21/8213H01L29/66143H01L29/872
    • Microelectronic structures and devices, and method of fabricating a three-dimensional microelectronic structure is provided, comprising passing a first precursor material for a selected three-dimensional microelectronic structure into a reaction chamber at temperatures sufficient to maintain said precursor material in a predominantly gaseous state; maintaining said reaction chamber under sufficient pressures to enhance formation of a first portion of said three-dimensional microelectronic structure; applying an electric field between an electrode and said microelectronic structure at a desired point under conditions whereat said first portion of a selected three-dimensional microelectronic structure is formed from said first precursor material; positionally adjusting either said formed three-dimensional microelectronic structure or said electrode whereby further controlled growth of said three-dimensional microelectronic structure occurs; passing a second precursor material for a selected three-dimensional microelectronic structure into a reaction chamber at temperatures sufficient to maintain said precursor material in a predominantly gaseous state; maintaining said reaction chamber under sufficient pressures whereby a second portion of said three-dimensional microelectronic structure formation is enhanced; applying an electric field between an electrode and said microelectronic structure at a desired point under conditions whereat said second portion of a selected three-dimensional microelectronic structure is formed from said second precursor material; and, positionally adjusting either said formed three-dimensional microelectronic structure or said electrode whereby further controlled growth of said three-dimensional microelectronic structure occurs.
    • 提供微电子结构和器件以及制造三维微电子结构的方法,包括在足以将所述前体材料维持在主要气态的温度下将用于选定的三维微电子结构的第一前体材料通入反应室; 将所述反应室保持在足够的压力下以增强所述三维微电子结构的第一部分的形成; 在所选择的三维微电子结构的所述第一部分由所述第一前体材料形成的条件下,在所需点处在电极和所述微电子结构之间施加电场; 位置地调整所述形成的三维微电子结构或所述电极,由此发生所述三维微电子结构的进一步控制的生长; 在足以将所述前体材料保持在主要气态的温度下,将用于选定的三维微电子结构的第二前体材料通入反应室; 将所述反应室保持在足够的压力下,从而提高所述三维微电子结构形成的第二部分; 在所选择的三维微电子结构的所述第二部分由所述第二前体材料形成的条件下,在所需点处在电极和所述微电子结构之间施加电场; 并且,位置地调整所述形成的三维微电子结构或所述电极,由此发生所述三维微电子结构的进一步控制的生长。
    • 68. 发明申请
    • USING NEW EDGES FOR ANOMALY DETECTION IN COMPUTER NETWORKS
    • 在计算机网络中使用新的边缘进行异常检测
    • US20140068769A1
    • 2014-03-06
    • US13826995
    • 2013-03-14
    • Los Alamos National Security, LLC
    • Joshua Charles Neil
    • H04L29/06
    • H04L63/1425G06F21/577G06N5/02G06N7/005H04L1/002H04L63/1408H04L63/1416H04L63/1433H04L2463/144
    • Creation of new edges in a network may be used as an indication of a potential attack on the network. Historical data of a frequency with which nodes in a network create and receive new edges may be analyzed. Baseline models of behavior among the edges in the network may be established based on the analysis of the historical data. A new edge that deviates from a respective baseline model by more than a predetermined threshold during a time window may be detected. The new edge may be flagged as potentially anomalous when the deviation from the respective baseline model is detected. Probabilities for both new and existing edges may be obtained for all edges in a path or other subgraph. The probabilities may then be combined to obtain a score for the path or other subgraph. A threshold may be obtained by calculating an empirical distribution of the scores under historical conditions.
    • 在网络中创建新的边缘可能被用作对网络的潜在攻击的指示。 可以分析网络中的节点创建和接收新边缘的频率的历史数据。 基于历史数据分析,可以建立网络边缘行为的基线模型。 可以检测在时间窗口期间偏离相应基线模型多于预定阈值的新边。 当检测到与各自基准模型的偏差时,新边缘可能被标记为潜在的异常。 可以为路径或其他子图中的所有边缘获得新边缘和现有边缘的概率。 然后可以组合概率以获得路径或其他子图的得分。 可以通过计算历史条件下分数的经验分布来获得阈值。
    • 70. 发明申请
    • Nitrogen-Doped Carbon-Supported Cobalt-Iron Oxygen Reduction Catalyst
    • 氮掺杂碳负载钴 - 铁氧还原催化剂
    • US20140024521A1
    • 2014-01-23
    • US14031939
    • 2013-09-19
    • Los Alamos National Security, LLC
    • Piotr ZelenayGang Wu
    • H01M4/90
    • H01M4/9083H01M4/9041H01M2008/1095
    • A Fe—Co hybrid catalyst for oxygen reaction reduction was prepared by a two part process. The first part involves reacting an ethyleneamine with a cobalt-containing precursor to form a cobalt-containing complex, combining the cobalt-containing complex with an electroconductive carbon supporting material, heating the cobalt-containing complex and carbon supporting material under conditions suitable to convert the cobalt-containing complex and carbon supporting material into a cobalt-containing catalyst support. The second part of the process involves polymerizing an aniline in the presence of said cobalt-containing catalyst support and an iron-containing compound conditions suitable to form a supported, cobalt-containing, iron-bound polyaniline species, and subjecting said supported, cobalt-containing, iron bound polyaniline species to conditions suitable for producing a Fe—Co hybrid catalyst.
    • 通过两部分方法制备用于氧反应还原的Fe-Co杂化催化剂。 第一部分涉及使乙烯胺与含钴前体反应以形成含钴络合物,将含钴络合物与导电碳载体材料结合,在适于转化含钴络合物的条件下加热含钴络合物和碳载体材料 含钴络合物和碳载体材料转化成含钴催化剂载体。 该方法的第二部分包括在所述含钴催化剂载体存在下聚合苯胺和适于形成负载的,含钴的,铁结合的聚苯胺种类的含铁化合物条件,并将所述负载的钴 - 含铁的结合聚苯胺类物质适用于生产Fe-Co杂化催化剂的条件。