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1. 发明授权

US08277881B2 White reflective coating for modified bitumen membrane 有权
标题翻译：白色反光涂层用于改性沥青膜
公开(公告)号：US08277881B2
公开(公告)日：2012-10-02
申请号：US10851580
申请日：2004-05-21
申请人： Amir Khan , Michael De Souto
发明人： Amir Khan , Michael De Souto
IPC分类号： B05D3/02
CPC分类号： C09D5/004
摘要： A coating composition useful for building materials products, especially roofing surfaces, is provided. The coating composition provides durable exterior protection to surfaces that it applied to, and it has reflective properties. The coating composition includes a mixture of a polymeric binder, a polymeric carrier and a pigment. The pigment is present in the coating composition in amount that is capable of providing a coating that has an initial energy efficiency rating greater than or equal to 0.65 for a low-sloped roof, or an initial energy efficiency greater than or equal to 0.25 for a steep-sloped roof.
摘要翻译：提供了可用于建筑材料产品，特别是屋顶表面的涂料组合物。涂料组合物对其所施加的表面提供耐用的外部保护，并具有反射性能。涂料组合物包括聚合物粘合剂，聚合物载体和颜料的混合物。该颜料以能够提供对于低倾斜屋顶具有大于或等于0.65的初始能效等级的涂层的量存在于涂料组合物中，或者对于陡峭的屋顶。

2. 发明申请

US20100224307A1 Fiberglass Splicing Method 审中-公开
标题翻译：玻璃纤维拼接方法
公开(公告)号：US20100224307A1
公开(公告)日：2010-09-09
申请号：US12729030
申请日：2010-03-22
申请人： Amir Khan , Burhan Uludag
发明人： Amir Khan , Burhan Uludag
IPC分类号： B29C65/14 , B29C65/52
CPC分类号： E04B1/66 , E04D5/148
摘要： A method of increasing the shear and tensile strength of spliced reinforcement panels used in roofing and waterproofing applications. The method is accomplished by facing and aligning at least two reinforcement panels in an end-to-end fashion on a roof deck in such a way that a seam is formed between the at least two reinforcement panels. A UV curable adhesive is then applied across the seam in a saw-tooth pattern and cured with a UV light source. The resultant spliced reinforcement panels will have a maximum load of approximately 34.4 to 48.8 lbf and a tensile strength of approximately 2.3 to 2.8%.
摘要翻译：一种提高屋顶和防水应用中使用的拼接加强板的剪切和拉伸强度的方法。该方法是通过在顶板上以端对端的方式面对和对准至少两个加强板而实现的，使得在至少两个加强板之间形成接缝。然后将UV可固化粘合剂以锯齿形图案施加在接缝上并用UV光源固化。所得到的拼接加强板将具有约34.4至48.8lbf的最大载荷和约2.3至2.8％的拉伸强度。

3. 发明申请

US20080207543A1 MODIFIED PITUITARY GLAND DEVELOPMENT IN OFFSPRING FROM EXPECTANT MOTHER ANIMALS TREATED WITH GROWTH HORMONE RELEASING HORMONE THERAPY 审中-公开
标题翻译：修改后的地区发展从预期的母亲动物处理与生长激素释放激素治疗
公开(公告)号：US20080207543A1
公开(公告)日：2008-08-28
申请号：US11774954
申请日：2007-07-09
申请人： Ruxandra Draghia-Akli , Amir Khan
发明人： Ruxandra Draghia-Akli , Amir Khan
IPC分类号： A61K31/7052 , C12N15/87 , A61P5/06
CPC分类号： C07K14/60 , A61K38/00 , A61K48/00 , A61K48/005
摘要： The intramuscular electroporated injection of a protease-resistant growth hormone-releasing hormone (“GHRH”) cDNA into rat dams at 16 days of gestation resulted in the enhanced long-term growth of the FI offspring. The offspring were significantly heavier by one week of age and the difference was sustained to 10 weeks of age. Consistent with their augmented growth, plasma IGF-I concentration of the FI progeny was increased significantly. The pituitary gland of the offspring was significantly heavier, and contained an increased number of somatotropes (cells producing GH) and lactotrophs (prolactin-secreting cells), and is indicative of an alteration in cell lineages. These unique findings demonstrate that enhanced GHRH expression in pregnant dams can result in intergenerational growth promotion, by altering development of the pituitary gland in the offspring.
摘要翻译：在16天的妊娠期间肌内电穿孔注射蛋白酶抗性生长激素释放激素（“GHRH”）cDNA进入大鼠大坝，导致FI后代的长期生长增强。后代明显比一周龄更重，差异持续到10周龄。与其增加的生长一致，FI后代的血浆IGF-I浓度显着增加。后代的垂体显着更重，并且含有增加的生长激素（产生GH的细胞）和乳酸营养素（催乳素分泌细胞）的数量增加，并且指示细胞谱系的改变。这些独特的研究结果表明，通过改变后代垂体的发育，怀孕水坝中GHRH表达增强可导致代际生长促进。

4. 发明申请

US20070095011A1 Fiberglass splicing method 审中-公开
标题翻译：玻璃纤维拼接方法
公开(公告)号：US20070095011A1
公开(公告)日：2007-05-03
申请号：US11242478
申请日：2005-10-03
申请人： Amir Khan , Burhan Uludag
发明人： Amir Khan , Burhan Uludag
IPC分类号： E04B1/00
CPC分类号： E04B1/66 , E04D5/148
摘要： A method for splicing reinforcement panels using a UV curable adhesive. The method includes the steps of: (a) aligning facing ends of two reinforcement panels; (b) applying adhesive on said facing ends of said two reinforcement panels; (c) butting together said facing ends of said two reinforcement panels; and (d) applying an ultraviolet light source to the adhesive. The method eliminates waste, reduces splicing time and improves the mechanical properties of the resultant mat.
摘要翻译：一种使用UV可固化粘合剂拼接加固板的方法。该方法包括以下步骤：（a）对准两个加强板的面对端; （b）在所述两个加强板的所述相对端上施加粘合剂; （c）将所述两个加强板的所述相对端对接在一起; 和（d）将紫外光源施加到粘合剂上。该方法消除了浪费，减少了拼接时间并改善了所得到的垫的机械性能。

5. 发明申请

US20060273290A1 Fire retardant composition 审中-公开
标题翻译：阻燃组成
公开(公告)号：US20060273290A1
公开(公告)日：2006-12-07
申请号：US11141829
申请日：2005-06-01
申请人： Amir Khan , Burhan Uludag , Michael De Souto
发明人： Amir Khan , Burhan Uludag , Michael De Souto
IPC分类号： C09K21/00
CPC分类号： C09K21/12
摘要： The present invention is directed to a fire retardant composition, comprising: a primer solution; expandable graphite particles; triethyl phosphate; and aluminum trihydrate, wherein the triethyl phosphate comprises from about 1 wt. % to about 15 wt. % based on the weight of the composition.
摘要翻译：本发明涉及一种阻燃组合物，其包含：底漆溶液; 可膨胀石墨颗粒; 磷酸三乙酯; 和三水合铝，其中磷酸三乙酯包含约1wt。％至约15wt。基于组合物的重量％。

6. 发明申请

US20060199453A1 Modified bitumen and thermoplastic composite roofing membrane 审中-公开
标题翻译：改性沥青和热塑性复合屋面膜
公开(公告)号：US20060199453A1
公开(公告)日：2006-09-07
申请号：US11429082
申请日：2006-05-05
申请人： William Kuhn , Amir Khan
发明人： William Kuhn , Amir Khan
IPC分类号： B32B27/04 , B32B27/12 , D04H11/00
CPC分类号： B32B5/26 , B32B11/10 , B32B17/04 , B32B27/02 , B32B27/32 , B32B2419/06 , E04D5/10 , Y10T428/23914 , Y10T428/23986 , Y10T428/23993 , Y10T442/133 , Y10T442/143 , Y10T442/148 , Y10T442/159 , Y10T442/164 , Y10T442/169 , Y10T442/171 , Y10T442/172 , Y10T442/174 , Y10T442/176 , Y10T442/178 , Y10T442/181 , Y10T442/183 , Y10T442/2631
摘要： A composite roofing membrane having a top layer of a thermoplastic polymer, a middle layer of a fleece material, and a bottom layer of modified bitumen joined together. The top and bottom layers may be reinforced with a reinforcing scrim.
摘要翻译：具有热塑性聚合物的顶层，羊毛材料的中间层和连接在一起的改性沥青的底层的复合屋顶膜。顶部和底部层可以用加强稀松布来增强。

7. 发明申请

US20060025368A1 Growth hormone releasing hormone enhances vaccination response 审中-公开
标题翻译：生长激素释放激素增强疫苗接种反应
公开(公告)号：US20060025368A1
公开(公告)日：2006-02-02
申请号：US11186282
申请日：2005-07-21
申请人： Ruxandra Draghia-Akli , Patricia Brown , Amir Khan , William Davis
发明人： Ruxandra Draghia-Akli , Patricia Brown , Amir Khan , William Davis
IPC分类号： A61K48/00 , C12N15/87
CPC分类号： A61K39/39 , A61K2039/55516
摘要： This invention discloses compositions and methods of: vaccinating a subject; enhancing the vaccination efficiency; preparing a subject prior to vaccination response; and improving the clinical outcome after infectious challenge in a subject that has been vaccinated. More specifically, the invention pertains to delivering into a tissue of the subject a nucleic acid expression construct that encodes a growth-hormone-releasing-hormone (“GHRH”) before or concomitantly with delivering a vaccine to the subject, wherein, GHRH is expressed in vivo in the subject, wherein the subject comprises a human, pig, cow, bird, horse or any other animal species receiving a vaccine.
摘要翻译：本发明公开了一种组合物和方法：接种受试者; 提高疫苗接种效率; 在接种疫苗接种前准备受试者; 并且在接种疫苗的受试者中感染性挑战后改善临床结果。更具体地，本发明涉及在受试者的组织中递送编码生长激素释放激素（“GHRH”）的核酸表达构建体，或者同时向受试者递送疫苗，其中，GHRH被表达在受试者体内，其中受试者包括人，猪，牛，鸟，马或接受疫苗的任何其他动物物种。

8. 发明申请

US20050257875A1 Process for coating modified bitumen membranes using reflective laminate coatings 审中-公开
标题翻译：使用反射层压涂层涂覆改性沥青膜的方法
公开(公告)号：US20050257875A1
公开(公告)日：2005-11-24
申请号：US10851602
申请日：2004-05-21
申请人： Amir Khan , Michael Souto
发明人： Amir Khan , Michael Souto
IPC分类号： B32B3/00 , B32B11/00 , B32B33/00 , E04D5/10 , B32B31/00
CPC分类号： B32B11/046 , B32B11/00 , B32B33/00 , B32B37/153 , B32B2307/416 , B32B2395/00 , B32B2419/06 , E04D5/10 , Y10T156/10 , Y10T428/24355 , Y10T428/24372 , Y10T428/25 , Y10T428/31855 , Y10T428/31931 , Y10T428/31935 , Y10T428/31938
摘要： A method of applying a laminate composition containing a whitening pigment during manufacture of modified bitumen roll roofing membranes, is provided. The laminate composition is heat activated providing greater adherence to surfaces that it applied to, and greater reflective properties. The laminate has an initial energy efficiency rating greater than or equal to 0.65 for a low-sloped roof, or an initial energy efficiency greater than or equal to 0.25 for a steep-sloped roof.
摘要翻译：提供了一种在改性沥青辊屋顶膜制造过程中应用含有增白颜料的层合组合物的方法。层压组合物是热活化的，提供对其施加的表面的更大的附着力和更大的反射性能。对于低倾斜屋顶，该层压板具有大于或等于0.65的初始能效等级，或者对于陡倾斜屋顶，其初始能量效率大于或等于0.25。

9. 发明授权

US08962818B2 Compositions comprising GHRH and GnRH and methods of using the same 有权
标题翻译：包含GHRH和GnRH的组合物及其使用方法
公开(公告)号：US08962818B2
公开(公告)日：2015-02-24
申请号：US12920545
申请日：2009-03-06
申请人： Ruxandra Draghia-Akli , Amir Khan , Patricia Brown
发明人： Ruxandra Draghia-Akli , Amir Khan , Patricia Brown
IPC分类号： A61K38/00 , A61K38/09 , A61K38/25 , A61K48/00
CPC分类号： A61K38/09 , A61K38/25 , A61K48/0016 , A61K48/005
摘要： Compositions and kits comprising a nucleotide sequence that encodes GHRH and a nucleotide sequence that encodes GnRH and compositions and kits comprising a GHRH protein and GnRH protein are disclosed. Use of such compositions and kits in methods of enhancing fertility in mammals comprising the step of administering said compositions to the mammal are disclosed.
摘要翻译：公开了包含编码GHRH的核苷酸序列和编码GnRH的核苷酸序列的组合物和试剂盒，以及包含GHRH蛋白质和GnRH蛋白质的组合物和试剂盒。公开了这样的组合物和试剂盒在增强哺乳动物生育力的方法中的用途，其包括向哺乳动物施用所述组合物的步骤。

10. 发明授权

US08829174B2 HCV vaccines and methods for using the same 有权
标题翻译： HCV疫苗及其使用方法
公开(公告)号：US08829174B2
公开(公告)日：2014-09-09
申请号：US13127008
申请日：2008-10-29
申请人： David B Weiner , Krystle A. Lang Kuhs , Jian Yan , Ruxandra Draghia-Akli , Amir Khan
发明人： David B Weiner , Krystle A. Lang Kuhs , Jian Yan , Ruxandra Draghia-Akli , Amir Khan
IPC分类号： C12N15/57 , C12N15/51 , C12N15/74 , C12N15/79 , C12N9/50
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/29 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/55 , C12N7/00 , C12N9/506 , C12N15/86 , C12N2710/24143 , C12N2770/24222 , C12N2770/24234
摘要： Improved anti-HCV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HCV genotype 1 a/1 b NS3 and NS4A. Pharmaceutical composition, recombinant vaccines comprising and live attenuated vaccines are disclosed as well methods of inducing an immune response in an individual against HCV are disclosed.
摘要翻译：公开了改进的抗HCV免疫原和编码它们的核酸分子。所公开的免疫原包括那些具有一致的HCV基因型1a / 1b NS3和NS4A的那些。公开了药物组合物，包含减毒活疫苗和减毒活疫苗的重组疫苗，并公开了针对HCV个体诱导免疫应答的方法。

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