专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20090242405A1 BOTTOM-UP ASSEMBLY OF STRUCTURES ON A SUBSTRATE 有权
标题翻译：底层结构的底部装配
公开(公告)号：US20090242405A1
公开(公告)日：2009-10-01
申请号：US12351509
申请日：2009-01-09
申请人： Theresa S. Mayer , Christine D. Keating , Mingwei Li , Thomas Morrow , Jaekyun Kim
发明人： Theresa S. Mayer , Christine D. Keating , Mingwei Li , Thomas Morrow , Jaekyun Kim
IPC分类号： G01N27/00 , H01L21/326 , B05D1/00 , H01L21/3205
CPC分类号： H01L29/0665 , B81B2203/0109 , B81B2207/056 , B81C1/00214 , B82Y10/00 , H01L29/0673 , H01L29/125 , H01L29/1606 , H01L29/772 , H01L29/7781 , H01L51/0037 , H01L51/0512
摘要： Examples of the present invention include methods of assembling structures, such as nanostructures, at predetermined locations on a substrate. A voltage between spaced-apart electrodes supported by substrate attracts the structures to the substrate, and positional registration can be provided the substrate using topographic features such as wells. Examples of the present invention also include devices, such as electronic and optoelectronic devices, prepared by such methods.
摘要翻译：本发明的实例包括在基底上的预定位置处组装诸如纳米结构的结构的方法。由衬底支撑的间隔开的电极之间的电压将结构吸引到衬底，并且可以使用诸如孔的地形特征为衬底提供位置配准。本发明的实例还包括通过这些方法制备的装置，例如电子和光电器件。

2. 发明授权

US08361297B2 Bottom-up assembly of structures on a substrate 有权
标题翻译：底部结构的自下而上组装
公开(公告)号：US08361297B2
公开(公告)日：2013-01-29
申请号：US12351509
申请日：2009-01-09
申请人： Theresa S. Mayer , Christine D. Keating , Mingwei Li , Thomas Morrow , Jaekyun Kim
发明人： Theresa S. Mayer , Christine D. Keating , Mingwei Li , Thomas Morrow , Jaekyun Kim
IPC分类号： B01D57/02 , G01N27/453
CPC分类号： H01L29/0665 , B81B2203/0109 , B81B2207/056 , B81C1/00214 , B82Y10/00 , H01L29/0673 , H01L29/125 , H01L29/1606 , H01L29/772 , H01L29/7781 , H01L51/0037 , H01L51/0512
摘要： Examples of the present invention include methods of assembling structures, such as nanostructures, at predetermined locations on a substrate. A voltage between spaced-apart electrodes supported by substrate attracts the structures to the substrate, and positional registration can be provided the substrate using topographic features such as wells. Examples of the present invention also include devices, such as electronic and optoelectronic devices, prepared by such methods.
摘要翻译：本发明的实例包括在基底上的预定位置处组装诸如纳米结构的结构的方法。由衬底支撑的间隔开的电极之间的电压将结构吸引到衬底，并且可以使用诸如孔的地形特征为衬底提供位置配准。本发明的实例还包括通过这些方法制备的装置，例如电子和光电器件。

3. 发明授权

US07655269B2 Integrated nanomechanical sensor array chips 失效
标题翻译：集成纳米机械传感器阵列芯片
公开(公告)号：US07655269B2
公开(公告)日：2010-02-02
申请号：US10423832
申请日：2003-04-25
申请人： Theresa S. Mayer , Christine D. Keating
发明人： Theresa S. Mayer , Christine D. Keating
IPC分类号： G01N1/33
CPC分类号： G01N33/54373 , Y10S977/702 , Y10S977/877
摘要： The invention provides sensor, preferably biosensor devices and method of fabrication. The devices have significant advantages over the prior art methods having compatibility with future trends in clinical diagnostics and chemical detection. The underlying principle involves the integration of nanometer diameter, micron long metal or semiconductor rods onto a substrate to form a suspended nanomechanical cantilevers. The cantilever rods are rigidly attached to the substrate on one or both ends, and resonate at a characteristic frequency depending on the diameter, length, and stiffness of the rod. The metal or semiconductor rods are integrated onto the substrate using electrofluidic or fluidic assembly techniques. A receptor coating is placed on the metal or semiconductor rods prior to or following rod alignment using self-assembly chemistries. Sensing is accomplished when the target agent binds to the receptor substance, causing a change in the mass of the cantilever rod, and a corresponding change in the resonant frequency. This change in resonant frequency can be detected using an electrical readout. The sensing circuitry is integrated with CMOS or TFT technologies to form compact multi-analyte senor arrays on single crystal silicon, glass, or polymeric substrates. Circuits can also be included on the substrate to transmit the array data via wireless methods to a remote workstation for analysis. Devices may be integrated on chips with other analysis devices.
摘要翻译：本发明提供了传感器，优选地是生物传感器装置和制造方法。与现有技术方法相比，这些装置具有与临床诊断和化学检测中的未来趋势相容的显着优点。其基本原理涉及将纳米直径，微米长金属或半导体棒整合到基底上以形成悬浮的纳米机械悬臂。悬臂杆在一端或两端刚性连接到基板上，并以取决于杆的直径，长度和刚度的特征频率共振。使用电流或流体组装技术将金属或半导体棒集成到衬底上。在使用自组装化学物质的杆对准之前或之后，将受体涂层放置在金属或半导体棒上。当靶剂与受体物质结合时，可以实现感应，引起悬臂杆质量的变化以及谐振频率的相应变化。可以使用电读出来检测谐振频率的这种变化。感测电路与CMOS或TFT技术集成，以在单晶硅，玻璃或聚合物基板上形成紧凑的多分析物传感器阵列。电路也可以包括在基板上，以通过无线方式将阵列数据传输到远程工作站进行分析。设备可以与其他分析设备集成在芯片上。

4. 发明授权

US07803405B2 Encapsulation of aqueous phase systems within microscopic volumes 有权
标题翻译：水相体系在微观体积内的封装
公开(公告)号：US07803405B2
公开(公告)日：2010-09-28
申请号：US10439578
申请日：2003-05-16
申请人： Christine D. Keating , Marcus R. Helfrich , M. Scott Long , Lauren K. Mangeney-Slavin
发明人： Christine D. Keating , Marcus R. Helfrich , M. Scott Long , Lauren K. Mangeney-Slavin
IPC分类号： A61K9/16 , A61K9/50
CPC分类号： B82Y5/00 , A61K9/127 , A61K47/6901
摘要： A means and method for preparing vesicles and freestanding two-dimensional assemblies using aqueous two-phase systems (ATPS) is described. The surface tension of the ATPS is sufficient to support the assembly of various types of particles, and provide the advantage of being biocompatible with DNA and other types of biological molecules that may be used in the assembly. Vesicles are formed by mixing chemically dissimilar compounds in appropriate concentrations and at a temperature sufficient to form a monophasic mixture. This mixture is then heated above the temperature at which the polymer mixture is monophasic, added to a lipid film, and allowed to hydrate at this elevated temperature.
摘要翻译：描述了使用水相两相体系（ATPS）制备囊泡和独立二维组件的方法和方法。 ATPS的表面张力足以支持各种类型的颗粒的组装，并且提供与可以用于组装中的DNA和其他类型的生物分子生物相容的优点。通过将化学上不同的化合物以适当浓度和足以形成单相混合物的温度混合形成囊泡。然后将该混合物加热至聚合物混合物为单相的温度，加入到脂质膜中，并在该升高的温度下使其水合。

5. 发明授权

US06579726B1 Instruments, methods and reagents for surface plasmon resonance 有权
标题翻译：用于表面等离子体共振的仪器，方法和试剂
公开(公告)号：US06579726B1
公开(公告)日：2003-06-17
申请号：US09629790
申请日：2000-07-31
申请人： Michael J. Natan , Glenn Goodrich , Lin He , L. Andrew Lyon , Michael D. Musick , Christine D. Keating
发明人： Michael J. Natan , Glenn Goodrich , Lin He , L. Andrew Lyon , Michael D. Musick , Christine D. Keating
IPC分类号： G01N33543
CPC分类号： C12Q1/6825 , B82Y15/00 , B82Y30/00 , G01N21/554 , G01N21/658 , Y10S435/808 , Y10S436/805 , C12Q2565/628 , C12Q2537/125 , C12Q2563/137
摘要： The invention provides methods and reagents for the enhancement of surface plasmon resonance (SPR)-based detection assays. The methods and reagents can be used in any molecular recognition assay that uses a solid support. The invention also provides an SPR instrument that operates in imaging mode.
摘要翻译：本发明提供用于增强基于表面等离子体共振（SPR）的检测分析的方法和试剂。方法和试剂可用于任何使用固体支持物的分子识别测定。本发明还提供一种以成像模式工作的SPR仪器。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式