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1. 发明申请

US20130210096A1 Methods and Systems for the Production of Hydrocarbon Products 有权
标题翻译：烃产品生产方法和系统
公开(公告)号：US20130210096A1
公开(公告)日：2013-08-15
申请号：US13579071
申请日：2011-10-21
申请人： Michael Anthony Schultz , James Obern , Sean Dennis Simpson
发明人： Michael Anthony Schultz , James Obern , Sean Dennis Simpson
IPC分类号： C12P7/54 , C12P7/06
CPC分类号： C12P7/54 , C01B3/38 , C01B2203/0233 , C01B2203/0283 , C01B2203/043 , C01B2203/06 , C01B2203/061 , C01B2203/1058 , C10G9/36 , C10G11/18 , C10G2300/1011 , C10G2300/708 , C10J2300/0943 , C10J2300/1681 , C10J2300/1846 , C10K3/026 , C12M21/04 , C12M43/00 , C12P5/02 , C12P7/06 , C12P7/065 , C12P7/18 , Y02E50/17 , Y02E50/343 , Y02P20/132 , Y02P20/146 , Y02P30/20
摘要： Methods and systems for the production of hydrocarbon products, including providing a substrate comprising CO to a bioreactor containing a culture of one or more micro-organisms; and fermenting the culture in the bioreactor to produce one or more hydrocarbon products. The substrate comprising CO is derived from an industrial process selected from the group comprising steam reforming processes, refinery processes, steam cracking processes, and reverse water gas shift processes.
摘要翻译：用于生产烃产品的方法和系统，包括向含有一种或多种微生物培养物的生物反应器提供包含CO的底物; 并在生物反应器中发酵培养物以产生一种或多种烃产物。包含CO的衬底源自选自蒸汽重整工艺，炼油工艺，蒸汽裂解工艺和反向水煤气变换工艺的工业过程。

2. 发明申请

US20120309075A1 Novel Bacteria and Methods of Use thereof 有权
标题翻译：新型细菌及其使用方法
公开(公告)号：US20120309075A1
公开(公告)日：2012-12-06
申请号：US13537798
申请日：2012-06-29
申请人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Loan Tran , Matthew James Rowe , Ian Linstrand Warner
发明人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Loan Tran , Matthew James Rowe , Ian Linstrand Warner
IPC分类号： C12N1/20
CPC分类号： C12R1/145 , C12N1/20 , C12P7/065 , C12P7/08 , C12P7/54 , Y02E50/17 , Y10S435/821 , Y10S435/842
摘要： A biologically pure isolate of a selected bacterium derived from Clostridium autoethanogenum is described which has improved efficiency in the production of ethanol by anaerobic fermentation of substrates comprising carbon monoxide. The bacterium can produce ethanol and acetate at an ethanol to acetate ratio of at least 1.0 and has a productivity of at least 1.2 g of ethanol/l of fermentation broth per day. The bacterium is also characterized in that it has substantially no ability to sporulate.
摘要翻译：描述了一种来源于自发性梭菌（Clostridium autoethanogenum）的选定细菌的生物纯的分离物，其通过包含一氧化碳的底物的厌氧发酵而提高了乙醇生产的效率。该细菌可以以至少1.0的乙醇与乙酸酯比率生产乙醇和乙酸盐，并且每天产生至少1.2g乙醇/ l的发酵液。细菌的特征还在于其基本上不具有孢子形成能力。

3. 发明申请

US20120252082A1 Fermentation Process For Controlling Butanediol Production 有权
标题翻译：用于控制丁二醇生产的发酵工艺
公开(公告)号：US20120252082A1
公开(公告)日：2012-10-04
申请号：US13435453
申请日：2012-03-30
申请人： Sean Dennis Simpson , Christophe Collet , Christophe Daniel Mihalcea , Joshua Jeremy Conolly , Guy William Waters
发明人： Sean Dennis Simpson , Christophe Collet , Christophe Daniel Mihalcea , Joshua Jeremy Conolly , Guy William Waters
IPC分类号： C12P7/54 , C12P7/52 , C12P7/18
CPC分类号： C12P7/18 , C12P7/065 , C12P7/54 , Y02E50/17
摘要： Methods for improving the efficiency of 2,3-butanediol fermentations are disclosed. More specifically methods of increasing the butanediol productivity from the anaerobic fermentation of a substrate comprising carbon monoxide or carbon monoxide and hydrogen by one or more caboxydotrophic acetogenic bacteria are disclosed. The method includes supplying a hydrogen depleted substrate to increase butanediol productivity. The method includes producing butanediol at a volumetric productivity rate of at least 15 g/L/day.
摘要翻译：公开了提高2,3-丁二醇发酵效率的方法。更具体地，公开了一种通过一种或多种脱氧营养型产乙酸细菌从包含一氧化碳或一氧化碳和氢气的基质的厌氧发酵中提高丁二醇生产率的方法。该方法包括提供贫氢基质以提高丁二醇的生产率。该方法包括以至少15g / L /天的体积生产率生产丁二醇。

4. 发明申请

US20110294177A1 OPTIMISED FERMENTATION MEDIA 有权
标题翻译：优化发酵媒体
公开(公告)号：US20110294177A1
公开(公告)日：2011-12-01
申请号：US13058375
申请日：2009-11-30
申请人： Sean Dennis Simpson , Ian Lindstrand Warner , Jennifer Mon Yee Eung , Michael Kopke
发明人： Sean Dennis Simpson , Ian Lindstrand Warner , Jennifer Mon Yee Eung , Michael Kopke
IPC分类号： C12P7/54 , C12P7/02 , C12P7/06 , C12P7/40 , C12N1/20
CPC分类号： C12N1/20 , C12P7/065 , C12P7/54 , Y02E50/17
摘要： The invention relates to improvements in the production of alcohols by microbial fermentation, particularly to production of alcohols by microbial fermentation of substrates comprising CO. It more particularly relates to the provision of an improved fermentation media, comprising nickel, to a fermentation system such that one or more micro-organisms convert a substrate comprising CO to one or more alcohols, such as ethanol. In particular embodiments, a microbial culture is provided with at least 10 μM nickel, such that CO uptake by the microbial culture increases and ethanol productivity improves.
摘要翻译：本发明涉及通过微生物发酵，特别是通过微生物发酵包含CO的底物生产醇的方法的改进。更具体地说，涉及向发酵系统提供包含镍的改进发酵培养基，使得一或更多的微生物将包含CO的底物转化成一种或多种醇，例如乙醇。在具体实施方案中，向微生物培养物提供至少10μM的镍，使得通过微生物培养物吸收的CO增加，乙醇生产率提高。

5. 发明申请

US20110257576A1 PERFUSION SYSTEM WITH RFID 有权
标题翻译：带RFID的灌注系统
公开(公告)号：US20110257576A1
公开(公告)日：2011-10-20
申请号：US12763561
申请日：2010-04-20
申请人： Dennis Simpson , Derek E. Dahlinger , Ivan Rossi
发明人： Dennis Simpson , Derek E. Dahlinger , Ivan Rossi
IPC分类号： A61M37/00
CPC分类号： A61B90/90 , A61M1/3624 , A61M1/3643 , A61M1/3666 , A61M2205/3317 , A61M2205/3375 , A61M2205/3389 , A61M2205/3569 , A61M2205/3592 , A61M2205/505
摘要： The disclosure pertains to a perfusion system that is easy to set-up, use and monitor during a bypass procedure. In some embodiments, the disclosure pertains to a perfusion system in which at least some of the disposable components used with the perfusion system are configured to be able to communicate set-up and/or operational parameters to the perfusion system. In some embodiments, the disclosure pertains to a blood level sensor that can be used to monitor a blood level or volume within a blood reservoir. The blood level sensor may be utilized in an integrated perfusion system in which the disposable components are configured, as noted above, to communicate with the perfusion system. In some embodiments, the blood level sensor may be utilized with a perfusion system lacking communication with disposables.
摘要翻译：本公开涉及在旁路过程中易于建立，使用和监测的灌注系统。在一些实施例中，本公开涉及灌注系统，其中与灌注系统一起使用的一次性部件中的至少一些被配置为能够将建立和/或操作参数传达到灌注系统。在一些实施例中，本公开涉及可用于监测血液储存器内的血液水平或体积的血液水平传感器。血液量传感器可以用在集成灌注系统中，其中如上所述配置一次性部件以与灌注系统进行通信。在一些实施例中，血液量传感器可以与缺乏与一次性物品通信的灌注系统一起使用。

6. 发明授权

US07972824B2 Microbial fermentation of gaseous substrates to produce alcohols 有权
标题翻译：气态底物的微生物发酵产生醇
公开(公告)号：US07972824B2
公开(公告)日：2011-07-05
申请号：US12296300
申请日：2007-04-05
申请人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew Rowe
发明人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew Rowe
IPC分类号： C12P7/02 , C12P7/06 , C12P3/00
CPC分类号： C12P7/14 , C12P7/54 , Y02E50/17
摘要： The present invention relates to methods for increasing the efficiency of anaerobic fermentation processes (1) that produce acetate as a by-product in addition to a desired product, and (2) that can utilize hydrogen and/or carbon dioxide in the fermentation. The method comprises the steps of converting acetate produced by the fermentation process into hydrogen gas and carbon dioxide gas, and utilizing hydrogen gas and/or carbon dioxide gas obtained from the acetate conversion in the anaerobic fermentation process. In particular aspects, the invention relates to processes of producing alcohols, particularly ethanol.
摘要翻译：本发明涉及提高厌氧发酵方法（1）的效率的方法（1），除了所需产物外，还可以生产作为副产物的乙酸酯，和（2）可以在发酵中利用氢和/或二氧化碳。该方法包括以下步骤：将通过发酵过程产生的乙酸转化为氢气和二氧化碳气体，并在厌氧发酵过程中利用由乙酸酯转化得到的氢气和/或二氧化碳气体。在具体方面，本发明涉及生产醇，特别是乙醇的方法。

7. 发明申请

US20090203100A1 Microbial Fermentation of Gaseous Substrates to Produce Alcohols 有权
标题翻译：气态底物微生物发酵生产酒精
公开(公告)号：US20090203100A1
公开(公告)日：2009-08-13
申请号：US12296300
申请日：2007-04-05
申请人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew Rowe
发明人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew Rowe
IPC分类号： C12P7/06 , C12P7/02
CPC分类号： C12P7/14 , C12P7/54 , Y02E50/17
摘要： The present invention relates to methods for increasing the efficiency of anaerobic fermentation processes (1) that produce acetate as a by-product in addition to a desired product, and (2) that can utilise hydrogen and/or carbon dioxide in the fermentation. The method comprises the steps of converting acetate produced by the fermentation process into hydrogen gas and carbon dioxide gas, and utilising hydrogen gas and/or carbon dioxide gas obtained from the acetate conversion in the anaerobic fermentation process. In particular aspects, the invention relates to processes of producing alcohols, particularly ethanol.
摘要翻译：本发明涉及提高厌氧发酵方法（1）的效率的方法（1），除了所需产物外，还可以生产作为副产物的乙酸酯，和（2）可以在发酵中利用氢和/或二氧化碳。该方法包括以下步骤：将通过发酵过程产生的乙酸转化为氢气和二氧化碳气体，并在厌氧发酵过程中利用由乙酸酯转化得到的氢气和/或二氧化碳气体。在具体方面，本发明涉及生产醇，特别是乙醇的方法。

8. 发明授权

US07175205B2 Collapsible utility trailer 失效
标题翻译：可折叠实用预告片
公开(公告)号：US07175205B2
公开(公告)日：2007-02-13
申请号：US11199320
申请日：2005-08-08
申请人： Dennis Simpson
发明人： Dennis Simpson
IPC分类号： B62D63/06
CPC分类号： B62D63/061
摘要： A collapsible utility trailer having a trailer bed, a trailer frame, a front pair of wheels and a rear pair of wheels. The trailer bed has at least two bed sections and each of the bed sections has a length and a width. The trailer frame has a plurality of frame sections and each of the trailer frame sections have a length and a width that are less than the length and the width of the bed sections, respectively. The trailer bed sections are attached to the trailer frame. The front and rear pairs of wheels rotatably attached to the trailer frame so that the front and rear wheels are oriented substantially below the trailer bed.
摘要翻译：具有拖车床，拖车框架，前一对车轮和后一对车轮的可折叠实用拖车。拖车床具有至少两个床部分，并且每个床部分具有长度和宽度。拖车框架具有多个框架部分，并且每个拖车框架部分分别具有小于床部分的长度和宽度的长度和宽度。拖车床部分连接到拖车框架。前轮和后轮对可旋转地附接到拖车架上，使得前轮和后轮大致定位在拖车床的下方。

9. 发明申请

US20050269813A1 Collapsible utility trailer 失效
公开(公告)号：US20050269813A1
公开(公告)日：2005-12-08
申请号：US11199320
申请日：2005-08-08
申请人： Dennis Simpson
发明人： Dennis Simpson
IPC分类号： B62D63/06
CPC分类号： B62D63/061
摘要： A collapsible utility trailer having a trailer bed, a trailer frame, a front pair of wheels and a rear pair of wheels. The trailer bed has at least two bed sections and each of the bed sections has a length and a width. The trailer frame has a plurality of frame sections and each of the trailer frame sections have a length and a width that are less than the length and the width of the bed sections, respectively. The trailer bed sections are attached to the trailer frame. The front and rear pairs of wheels rotatably attached to the trailer frame so that the front and rear wheels are oriented substantially below the trailer bed.

10. 发明申请

US20050042463A1 Multi-layer composites formed from compositions having improved adhesion, coating compositions, and methods related thereto 有权
标题翻译：由具有改进的粘附性，涂层组合物和与其相关的方法的组合物形成的多层复合材料
公开(公告)号：US20050042463A1
公开(公告)日：2005-02-24
申请号：US10935643
申请日：2004-09-07
申请人： Lawrence Anderson , John Burgman , Karen Morow , Richard Sadvary , Shiryn Tyebjee , Dennis Simpson , Thomas Hockswender
发明人： Lawrence Anderson , John Burgman , Karen Morow , Richard Sadvary , Shiryn Tyebjee , Dennis Simpson , Thomas Hockswender
IPC分类号： B32B27/18 , B05D7/00 , C08J5/12 , C08K3/38 , C08K5/06 , C08K5/55 , C08L83/04 , C08L83/05 , C09D7/12 , C09D133/00 , C09D167/00 , C09D171/00 , C09D175/04 , C09D183/00 , C09D183/05 , C09D183/06 , C09D183/07 , C09D183/08 , C09J11/00 , C09J183/05 , C09J183/06 , C09J183/07 , C09J183/08 , B32B27/30 , B32B27/36
CPC分类号： B05D7/57 , B05D7/574 , C08J5/12 , C08K3/38 , C08K5/55 , C09D7/60 , Y10T428/31511 , Y10T428/31663 , Y10T428/31725 , Y10T428/31786 , Y10T428/31935
摘要： The present invention provides an improved multi-layer composite of two or more polymeric layers at least one of which is formed from a thermosetting composition. The composite includes at least a first polymeric layer formed on a substrate and a second polymeric layer over the first polymeric layer, wherein in the absence of a boron-containing compound, the first and second polymeric layers have poor interlayer adhesion. The improvement resides in the inclusion of at least one boron-containing compound in one or both of the first and second polymeric layers in an amount sufficient to improve the interlayer adhesion between the first and second polymeric layers. Also provided is an improved curable coating composition used to form a multi-layer composite coating of two or more cured coating layers, at least one of which is formed from the thermosetting composition. Related methods and coated substrates are also provided.
摘要翻译：本发明提供了两种或更多种聚合物层的改进的多层复合材料，其中至少一种由热固性组合物形成。所述复合材料包括形成在基材上的至少第一聚合物层和在所述第一聚合物层上的第二聚合物层，其中在不存在含硼化合物的情况下，所述第一和第二聚合物层具有差的层间粘合性。改进在于在足以改善第一和第二聚合物层之间的层间粘合力的量中将至少一种含硼化合物包含在第一和第二聚合物层的一个或两个中。还提供了一种改进的可固化涂料组合物，其用于形成两层或多层固化涂层的多层复合涂层，其中至少一层由热固性组合物形成。还提供了相关方法和涂覆的基底。

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