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1. 发明授权

US09463323B2 Spatially selective nerve stimulation in high-frequency nerve conduction block and recruitment 有权
标题翻译：空间选择性神经刺激在高频神经传导阻滞和招募
公开(公告)号：US09463323B2
公开(公告)日：2016-10-11
申请号：US12819107
申请日：2010-06-18
申请人： Dongchul Lee , Bradley Hershey , Kerry Bradley
发明人： Dongchul Lee , Bradley Hershey , Kerry Bradley
IPC分类号： A61N1/00 , A61N1/36 , A61N1/06
CPC分类号： A61N1/36167 , A61N1/06 , A61N1/36007 , A61N1/36071
摘要： A method of providing therapy to a patient using at least one electrode is provided. The patient has a neural tissue region that is relatively close to the at least one electrode, and a neural tissue region that is relatively far from the at least one electrode. The method comprises conveying time-varying electrical energy from the electrode(s) into the relatively close and far neural tissue regions, wherein the electrical energy has a frequency and amplitude that blocks stimulation of the relatively close neural tissue region, while stimulating the relatively far neural tissue region.
摘要翻译：提供了使用至少一个电极向患者提供治疗的方法。患者具有相对靠近至少一个电极的神经组织区域和相对远离至少一个电极的神经组织区域。该方法包括将时间变化的电能从电极传送到相对靠近和远的神经组织区域，其中电能具有阻止刺激相对较近的神经组织区域的频率和幅度，同时刺激相对较远神经组织区域。

2. 发明授权

US09463321B2 System and method for adjusting automatic pulse parameters to selectively activate nerve fibers 有权
标题翻译：用于调节自动脉冲参数以选择性地激活神经纤维的系统和方法
公开(公告)号：US09463321B2
公开(公告)日：2016-10-11
申请号：US12606050
申请日：2009-10-26
申请人： Kerry Bradley , Bradley Hershey , Dongchul Lee
发明人： Kerry Bradley , Bradley Hershey , Dongchul Lee
IPC分类号： A61N1/08 , A61N1/36 , A61N1/372
CPC分类号： A61N1/36192 , A61N1/36071 , A61N1/37247
摘要： A method of stimulating nerve tissue, a tissue stimulation system, and an external control device are provided. The method, system, and control device cause an electrical stimulus to be applied to at least one electrode adjacent the nerve tissue of a patient. The applied electrical stimulus comprises a plurality of pulses defined by a pulse width value and an amplitude value. The pulse amplitude value is increased (e.g., manually), and the pulse width value is automatically decreased in response to increasing the pulse amplitude value in a manner that increases the intensity of the applied electrical stimulus. Alternatively, the pulse width value may be decreased (e.g., manually), and the pulse amplitude value automatically increased in response to decreasing the pulse width value in a manner that increases the intensity of the applied electrical stimulus.
摘要翻译：提供刺激神经组织，组织刺激系统和外部控制装置的方法。该方法，系统和控制装置使电刺激施加到邻近患者神经组织的至少一个电极。所施加的电刺激包括由脉冲宽度值和振幅值定义的多个脉冲。脉冲幅度值增加（例如，手动），并且响应于以增加所施加的电刺激的强度的方式增加脉冲幅值来自动减小脉冲宽度值。或者，可以减小脉冲宽度值（例如，手动地），并且响应于以增加所施加的电刺激的强度的方式减小脉冲宽度值，脉冲振幅值自动增加。

3. 发明授权

US08789510B2 Throttle valve device including control logic of throttle valve for diesel vehicle and the control method thereof 有权
标题翻译：节流阀装置包括柴油车辆节流阀的控制逻辑及其控制方法
公开(公告)号：US08789510B2
公开(公告)日：2014-07-29
申请号：US13284468
申请日：2011-10-28
申请人： Heungseok Lee , Jaemin Jin , Sukil Oh , Dongchul Lee , Insoo Jung
发明人： Heungseok Lee , Jaemin Jin , Sukil Oh , Dongchul Lee , Insoo Jung
IPC分类号： F02D41/16 , F02D11/10 , F02M25/07 , F02B47/08
CPC分类号： F02D9/02 , F02B3/06 , F02D21/08 , F02D41/0002 , F02D41/0052 , F02D41/0225 , F02D41/16 , F02D2041/0022 , F02D2200/021 , F02D2200/101 , F02D2200/602 , F02D2200/703 , Y02T10/42 , Y02T10/47
摘要： A throttle valve device including a throttle valve control logic may include an electronic controller that determines whether a driving state of a vehicle is an idle-driving state from electronic signals supplied from sensors, a desired air amount map unit that is electrically connected with the electronic controller and where a desired amount of air according to RPM of an engine and an amount of injected fuel for idle-driving are set; and a governor for controlling an EGR valve and a governor for controlling a throttle valve that are electrically connected with the electronic controller and the desired air amount map unit and control the driving of the EGR valve and the throttle valve, respectively, such that the desired amount of air output in accordance with the RPM of the engine of the vehicle and an amount of the injected fuel is supplied to the engine in the idle-driving.
摘要翻译：包括节流阀控制逻辑的节气门装置可以包括电子控制器，其通过从传感器提供的电子信号来确定车辆的行驶状态是否为怠速行驶状态，与电子电气连接的期望空气量图单元控制器，并且其中设定根据发动机的RPM和空载驱动的喷射燃料量的期望量的空气; 以及用于控制EGR阀的调速器和用于控制与电子控制器和所需空气量映射单元电连接的节流阀的调速器，并且分别控制EGR阀和节流阀的驱动，使得期望的在怠速驾驶中，依照车辆的发动机的RPM的空气输出量和喷射的燃料的量被供给到发动机。

4. 发明授权

US08355798B2 System and method for increasing relative intensity between cathodes and anodes of neurostimulation system using pulse slicing 有权
标题翻译：使用脉冲切片增加阴极和神经刺激系统阳极之间的相对强度的系统和方法
公开(公告)号：US08355798B2
公开(公告)日：2013-01-15
申请号：US12612528
申请日：2009-11-04
申请人： Dongchul Lee
发明人： Dongchul Lee
IPC分类号： A61N1/08
CPC分类号： A61N1/36146 , A61N1/0553 , A61N1/36167
摘要： A method and neurostimulation system for providing therapy to a patient is provided. A plurality of electrodes is placed adjacent to tissue of the patient. A plurality of first electrical pulses is delivered to a first set of the electrodes, at least a second electrical pulse is delivered to a second set of the electrodes during the deliverance of each of the first electrical pulses, and at least a third electrical pulse is delivered to a third set of the electrodes during the deliverance of each of the first electrical pulses. The first electrical pulses have a first polarity, and each of the second electrical pulse(s) and third electrical pulses(s) has a second a second polarity opposite to the first polarity. The second and third electrical pulses are temporarily offset from each other.
摘要翻译：提供了一种用于向患者提供治疗的方法和神经刺激系统。多个电极邻近患者的组织放置。多个第一电脉冲被传送到第一组电极，在每个第一电脉冲的释放期间，至少第二电脉冲被传送到第二组电极，并且至少第三电脉冲是在每个第一电脉冲的释放期间传送到第三组电极。第一电脉冲具有第一极性，并且第二电脉冲和第三电脉冲中的每一个具有与第一极性相反的第二极性。第二和第三电脉冲彼此临时偏移。

5. 发明申请

US20120041518A1 NEUROSTIMULATION SYSTEM AND METHOD WITH GRAPHICALLY MANIPULATABLE STIMULATION TARGET 审中-公开
标题翻译：神经系统和方法与图形可控的刺激目标
公开(公告)号：US20120041518A1
公开(公告)日：2012-02-16
申请号：US13197987
申请日：2011-08-04
申请人： Chester Kim , Dongchul Lee
发明人： Chester Kim , Dongchul Lee
IPC分类号： A61N1/08
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36182 , G06F19/3481 , G16H40/63
摘要： An external control device for use with a neurostimulation device having a plurality of electrodes carried by at least one neurostimulation lead. The external control device comprises a display screen configured for displaying at least one object relative to a graphical representation of the neurostimulation lead(s). The object(s) represents an abstraction of a stimulation target. The external control device further comprises detection circuitry configured for detecting an actuation event that includes placing at least one pointing element in proximity to the object(s). The external control device further comprises processing circuitry configured for manipulating the object(s) on the display screen in response to the detection of the actuation event, thereby modifying the stimulation target abstraction, and for generating a set of stimulation parameters that emulates the modified stimulation target abstraction. The external control device further comprises output circuitry configured for transmitting the set of stimulation parameters to the neurostimulation device.
摘要翻译：一种与神经刺激装置一起使用的外部控制装置，具有由至少一个神经刺激引线携带的多个电极。外部控制装置包括被配置为相对于神经刺激引线的图形表示显示至少一个对象的显示屏幕。对象表示刺激目标的抽象。外部控制装置还包括被配置用于检测致动事件的检测电路，其包括将至少一个指示元件放置在物体附近。外部控制装置还包括处理电路，其被配置为响应于激活事件的检测来操纵显示屏上的对象，由此修改刺激目标抽象，并且用于生成模拟修改刺激的一组刺激参数目标抽象。外部控制装置还包括被配置为将刺激参数集合发送到神经刺激装置的输出电路。

6. 发明申请

US20100331926A1 REVERSING RECRUITMENT ORDER BY ANODE INTENSIFICATION 审中-公开
标题翻译：通过阳极强化反向招聘订单
公开(公告)号：US20100331926A1
公开(公告)日：2010-12-30
申请号：US12821005
申请日：2010-06-22
申请人： Dongchul Lee , Kerry Bradley , David K.L. Peterson
发明人： Dongchul Lee , Kerry Bradley , David K.L. Peterson
IPC分类号： A61N1/36
CPC分类号： A61N1/36071 , A61N1/36185 , A61N1/37241 , A61N1/375 , A61N1/3787
摘要： A method of providing therapy to a patient using a plurality of electrodes is provided. The electrodes are located adjacent a target neural tissue region having a first nerve fiber of a relatively small diameter and a second nerve fiber of a relatively large diameter. The method comprises sourcing electrical current from a local anode into the target neural tissue region. The method further comprises therapeutically sinking a first portion of the electrical current from the target neural tissue region into a local cathode. The method further comprises sinking a second portion of the electrical current into a cathode remote from the target neural tissue region. The ratio of the sourced electrical current over the first sunk electrical current portion has a value that allows the first nerve fiber to be recruited by the electrical current while preventing the second nerve fiber from being recruited by the electrical current.
摘要翻译：提供了一种使用多个电极向患者提供治疗的方法。电极位于具有相对小直径的第一神经纤维和相对较大直径的第二神经纤维的靶神经组织区域附近。该方法包括将电流从局部阳极引入目标神经组织区域。该方法还包括将来自目标神经组织区域的电流的第一部分治疗性地吸入局部阴极。该方法还包括将电流的第二部分吸收到远离目标神经组织区域的阴极中。源头电流与第一沉没电流部分的比率具有允许第一神经纤维通过电流招募的值，同时防止第二神经纤维被电流招募。

7. 发明申请

US20100324630A1 SPATIALLY SELECTIVE NERVE STIMULATION IN HIGH-FREQUENCY NERVE CONDUCTION BLOCK AND RECRUITMENT 有权
标题翻译：高频神经阻滞和招募中的空间选择性神经刺激
公开(公告)号：US20100324630A1
公开(公告)日：2010-12-23
申请号：US12819107
申请日：2010-06-18
申请人： Dongchul Lee , Bradley Hershey , Kerry Bradley
发明人： Dongchul Lee , Bradley Hershey , Kerry Bradley
IPC分类号： A61N1/36
CPC分类号： A61N1/36167 , A61N1/06 , A61N1/36007 , A61N1/36071
摘要： A method of providing therapy to a patient using at least one electrode is provided. The patient has a neural tissue region that is relatively close to the at least one electrode, and a neural tissue region that is relatively far from the at least one electrode. The method comprises conveying time-varying electrical energy from the electrode(s) into the relatively close and far neural tissue regions, wherein the electrical energy has a frequency and amplitude that blocks stimulation of the relatively close neural tissue region, while stimulating the relatively far neural tissue region.
摘要翻译：提供了使用至少一个电极向患者提供治疗的方法。患者具有相对靠近至少一个电极的神经组织区域和相对远离至少一个电极的神经组织区域。该方法包括将时间变化的电能从电极传送到相对靠近和远的神经组织区域，其中电能具有阻止刺激相对较近的神经组织区域的频率和幅度，同时刺激相对较远神经组织区域。

8. 发明申请

US20100137962A1 IMPLANTABLE NEUROSTIMULATORS HAVING REDUCED POCKET STIMULATION 审中-公开
公开(公告)号：US20100137962A1
公开(公告)日：2010-06-03
申请号：US12630633
申请日：2009-12-03
申请人： Michael A. Moffitt , Dongchul Lee
发明人： Michael A. Moffitt , Dongchul Lee
IPC分类号： A61N1/00
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.

9. 发明申请

US20100137960A1 IMPLANTABLE NEUROSTIMULATORS HAVING REDUCED POCKET STIMULATION 审中-公开
标题翻译：具有减少口袋刺激的可植入神经细胞
公开(公告)号：US20100137960A1
公开(公告)日：2010-06-03
申请号：US12629814
申请日：2009-12-02
申请人： Michael A. Moffitt , Dongchul Lee , Kerry Bradley
发明人： Michael A. Moffitt , Dongchul Lee , Kerry Bradley
IPC分类号： A61N1/00
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.
摘要翻译：提供神经刺激器和使用神经刺激器的方法。将神经刺激器植入患者的组织袋中，并且电能从神经刺激器传送以刺激远离组织袋的靶组织部位。神经刺激器具有与一个或多个电极相关联的情况。电能以防止或至少减少由于电能返回到神经刺激器的情况而可能发生的口袋刺激的方式返回到电极。

10. 发明申请

US20100057162A1 MULTIPLE TUNABLE CENTRAL CATHODES ON A PADDLE FOR INCREASED MEDIAL-LATERAL AND ROSTRAL-CAUDAL FLEXIBILITY VIA CURRENT STEERING 有权
公开(公告)号：US20100057162A1
公开(公告)日：2010-03-04
申请号：US12204094
申请日：2008-09-04
申请人： Michael Moffitt , Dongchul Lee , Kerry Bradley , David K.L. Peterson
发明人： Michael Moffitt , Dongchul Lee , Kerry Bradley , David K.L. Peterson
IPC分类号： A61N1/34 , A61N1/05
CPC分类号： A61N1/0551 , A61N1/0553 , A61N1/36071
摘要： A neurostimulation paddle lead, method of neurostimulation, and neurostimulation system are provided. The neurostimulation paddle lead carries a plurality of electrodes comprising at least four columns of electrodes having a spacing between two inner electrode columns less than a spacing between the inner electrode columns and adjacent outer electrode columns. The inner electrode columns may also be longitudinally offset from the outer electrode columns. The methods and neurostimulation systems steer current between the electrodes to modify a medial-lateral electrical field created adjacent spinal cord tissue.

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