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1. 发明授权

US08706195B2 Method for producing an electrophysiological map of the heart 有权
标题翻译：产生心脏电生理图的方法
公开(公告)号：US08706195B2
公开(公告)日：2014-04-22
申请号：US12599225
申请日：2008-05-11
申请人： Gera Strommer , Uzi Eichler , Liat Schwartz , Arnit Cohen
发明人： Gera Strommer , Uzi Eichler , Liat Schwartz , Arnit Cohen
IPC分类号： A61B5/00
CPC分类号： A61B5/042 , A61B5/04011 , A61B5/7445 , A61B6/503 , A61B6/504 , A61B34/20 , A61B34/25 , A61B90/36 , A61B2034/105 , A61B2034/2051 , A61B2090/364
摘要： Method and system for producing an electrophysiological map of a heart of the body of a patient, the method including, for at least one target point, determining a respective target point location and a respective probe orientation, confirming that the tip of a probe is located at the respective target point location, confirming that the tip is oriented at the respective probe orientation, measuring at least one heart parameter value at the respective target point location, and superimposing at least one representation of the at least one heart parameter value on an image of the heart, at the respective target point location, to produce the electrophysiological map.
摘要翻译：用于产生患者身体的心脏的电生理图的方法和系统，所述方法包括针对至少一个目标点确定相应的目标点位置和相应的探针取向，确认探针的尖端位于在相应的目标点位置处，确认尖端被定向在相应的探针取向，测量相应目标点位置处的至少一个心脏参数值，并且将至少一个心脏参数值的至少一个表示叠加在图像上的心脏，在各自的目标点位置，以产生电生理图。

2. 发明授权

US08055327B2 Automatic guidewire maneuvering system and method 有权
标题翻译：自动导丝机动系统及方法
公开(公告)号：US08055327B2
公开(公告)日：2011-11-08
申请号：US10940423
申请日：2004-09-14
申请人： Gera Strommer , Uzi Eichler , Lior Sobe
发明人： Gera Strommer , Uzi Eichler , Lior Sobe
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B1/00147 , A61B5/065 , A61B6/03 , A61B6/541 , A61B34/20 , A61B34/70 , A61B2017/00703 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2053 , A61B2034/301 , A61B2034/742 , A61M25/0113 , A61M25/0133 , A61M25/0158 , A61M25/09041 , A61M2025/0166 , A61M2025/09183 , A61M2205/3515
摘要： Method for guiding a catheter within a lumen system of the body of a patient includes receiving consecutive position inputs from a user to guide the catheter in real time within the lumen system, determining a user defined position for the catheter tip determining continuously successive incremental paths along a trail defined by a plurality of user defined positions, and directing a moving mechanism to incrementally move the catheter within the lumen system along each of the incremental paths, each of the user defined positions being determined for each of the received consecutive position inputs, the successive incremental paths being determined between a real time catheter tip position and the adjacent proceeding user defined position, according to a topological representation of the lumen system, the moving mechanism being directed to incrementally move the catheter from each of a plurality of real time positions, toward the adjacent proceeding user defined position.
摘要翻译：用于在患者身体的管腔系统内引导导管的方法包括从使用者接收连续的位置输入以在管腔系统内实时引导导管，确定导管尖端的用户定义的位置，以连续地确定连续的逐渐增加的路径由多个用户定义的位置限定的轨迹，并且引导移动机构沿着每个增量路径递增地移动管腔系统内的导管，每个用户定义的位置是为每个所接收的连续位置输入确定的，根据管腔系统的拓扑表示，在实时导管尖端位置和相邻进行的用户限定位置之间确定连续的增量路径，所述移动机构被引导以从多个实时位置中的每一个增量地移动导管，朝向相邻进行的用户定义的位置。

3. 发明申请

US20110054308A1 METHOD AND SYSTEM FOR SUPERIMPOSING VIRTUAL ANATOMICAL LANDMARKS ON AN IMAGE 有权
标题翻译：用于超图像的虚拟解剖图的方法和系统
公开(公告)号：US20110054308A1
公开(公告)日：2011-03-03
申请号：US12941514
申请日：2010-11-08
申请人： Amit Cohen , Gera Strommer , Uzi Eichler
发明人： Amit Cohen , Gera Strommer , Uzi Eichler
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B5/015 , A61B5/0456 , A61B5/062 , A61B5/066 , A61B5/706 , A61B5/7425 , A61B5/7475 , A61B6/0492 , A61B6/12 , A61B6/4441 , A61B6/465 , A61B6/466 , A61B6/469 , A61B6/5247 , A61B8/0833 , A61B8/12 , A61B8/40 , A61B8/5238 , A61B34/10 , A61B34/20 , A61B2017/00243 , A61B2017/00703 , A61B2034/2051 , A61B2034/2072 , A61B2090/364 , A61B2090/365 , A61B2090/376 , A61B2090/3958
摘要： A system for superimposing virtual anatomical landmarks on an image includes a medical positioning system (MPS) for producing location readings with respect to points within a region of interest in accordance with an output of a location sensor disposed in a medical device. A coordinate system of the MPS is registered with an image coordinate system. A control unit receives a signal from a user to record a location reading when the medical device is at a desired point in the region of interest where the user desires to place a virtual landmark, modifies the recorded location reading for motion compensation, transforms the motion-compensated location reading from the MPS coordinate system to the image coordinate system to produce a target location, and then superimposes a representation of the virtual landmark on the image at the target location.
摘要翻译：用于将虚拟解剖标志叠加在图像上的系统包括用于根据设置在医疗装置中的位置传感器的输出产生相对于感兴趣区域内的点的位置读数的医疗定位系统（MPS）。 MPS的坐标系被记录在图像坐标系中。控制单元接收来自用户的信号，以便当医疗设备位于用户期望放置虚拟地标的感兴趣区域中的期望点处时，记录位置读数，修改用于运动补偿的记录位置读数，转换运动 - 从MPS坐标系向图像坐标系的补偿位置读取以产生目标位置，然后将虚拟界标的表示叠加在目标位置的图像上。

4. 发明申请

US20110021903A1 Method for producing an electrophysiological map of the heart 有权
标题翻译：产生心脏电生理图的方法
公开(公告)号：US20110021903A1
公开(公告)日：2011-01-27
申请号：US12599225
申请日：2008-05-11
申请人： Gera Strommer , Uzi Eichler , Liat Schwartz , Arnit Cohen
发明人： Gera Strommer , Uzi Eichler , Liat Schwartz , Arnit Cohen
IPC分类号： A61B5/042 , A61N1/362 , A61B8/12 , A61B5/055 , A61B5/053 , A61B6/00
CPC分类号： A61B5/042 , A61B5/04011 , A61B5/7445 , A61B6/503 , A61B6/504 , A61B34/20 , A61B34/25 , A61B90/36 , A61B2034/105 , A61B2034/2051 , A61B2090/364
摘要： Method for producing an electrophysiological map of a heart of the body of a patient, the method including the procedures of determining a respective target point location, and a respective probe orientation, confirming that the tip of a probe catheter is located at the respective target point location, confirming that the tip is oriented at the respective probe orientation, measuring the heart parameter value at each of the respective target point locations, and superimposing a plurality of representations respective of the heart parameter value, the respective target point location, and the respective probe orientation being determined with respect to heart parameter value which is to be measured, for each of a plurality of target points within the heart, the tip of a probe catheter being confirmed that it is located at the respective target point location, by comparing the currently detected location of the tip, with the respective target point location, the tip being confirmed that it is oriented at the respective probe orientation, by comparing the currently detected orientation of the tip, with the respective probe orientation, heart parameter value being measured at each of the respective target point locations, by a heart parameter sensor located at the tip, the representations respective of the at least one heart parameter value, being superimposed on an image of the heart, at the respective target point location, to produce the electrophysiological map.
摘要翻译：用于产生患者身体的心脏的电生理图的方法，所述方法包括确定各个目标点位置的程序和相应的探针取向，确认探针导管的尖端位于相应的目标点确定所述尖端被定向在相应的探针方向，测量各个目标点位置中的每一个处的心脏参数值，并且叠加多个表示心脏参数值，相应目标点位置和相应的目标点位置针对心脏中的多个目标点中的每一个确定针对待测量的心脏参数值的探针取向，通过将探针导管的尖端确定为位于相应的目标点位置，当前检测到尖端的位置，具有相应的目标点位置，尖端被确认通过将位于尖端处的心脏参数传感器，通过比较当前检测到的尖端的取向与相应的探针取向，在各个目标点位置的每一个处测量的心脏参数值，在相应的目标点位置处叠加在心脏图像上的至少一个心脏参数值的表示，以产生电生理图。

5. 发明授权

US07811294B2 Automatic guidewire maneuvering system and method 有权
标题翻译：自动导丝机动系统及方法
公开(公告)号：US07811294B2
公开(公告)日：2010-10-12
申请号：US10800129
申请日：2004-03-08
申请人： Gera Strommer , Uzi Eichler , Lior Sobe
发明人： Gera Strommer , Uzi Eichler , Lior Sobe
IPC分类号： A61F11/00
CPC分类号： A61B5/06 , A61B1/00147 , A61B5/065 , A61B6/03 , A61B6/541 , A61B34/20 , A61B34/70 , A61B2017/00703 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2053 , A61B2034/301 , A61B2034/742 , A61M25/0113 , A61M25/0133 , A61M25/0158 , A61M25/09041 , A61M2025/0166 , A61M2025/09183 , A61M2205/3515
摘要： System for guiding a catheter through a lumen system of a body of a patient, to a predetermined location within the lumen system, the system including a medical positioning system, a moving mechanism coupled with the catheter, and a controller coupled with the medical positioning system and with the moving mechanism, the medical positioning system including at least one position detector, the position detector being firmly attached to a distal portion of the catheter, the medical positioning system determining the position of the position detector, the controller controlling the operation of the moving mechanism to move the catheter to the predetermined location, according to the position and according to a topological representation of at least a portion of the lumen system.
摘要翻译：用于将导管引导通过患者身体的管腔系统到管腔系统内的预定位置的系统，所述系统包括医疗定位系统，与导管联接的移动机构，以及与医疗定位系统并且利用移动机构，医疗定位系统包括至少一个位置检测器，位置检测器牢固地附接到导管的远端部分，医疗定位系统确定位置检测器的位置，控制器控制移动机构，以根据位置和根据管腔系统的至少一部分的拓扑表示将导管移动到预定位置。

6. 发明申请

US20050197557A1 Automatic guidewire maneuvering system and method 有权
标题翻译：自动导丝机动系统及方法
公开(公告)号：US20050197557A1
公开(公告)日：2005-09-08
申请号：US10800129
申请日：2004-03-08
申请人： Gera Strommer , Uzi Eichler , Lior Sobe
发明人： Gera Strommer , Uzi Eichler , Lior Sobe
IPC分类号： A61B5/05 , A61B5/06 , A61B6/00 , A61B6/03
CPC分类号： A61B5/06 , A61B1/00147 , A61B5/065 , A61B6/03 , A61B6/541 , A61B34/20 , A61B34/70 , A61B2017/00703 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2053 , A61B2034/301 , A61B2034/742 , A61M25/0113 , A61M25/0133 , A61M25/0158 , A61M25/09041 , A61M2025/0166 , A61M2025/09183 , A61M2205/3515
摘要： System for guiding a catheter through a lumen system of a body of a patient, to a predetermined location within the lumen system, the system including a medical positioning system, a moving mechanism coupled with the catheter, and a controller coupled with the medical positioning system and with the moving mechanism, the medical positioning system including at least one position detector, the position detector being firmly attached to a distal portion of the catheter, the medical positioning system determining the position of the position detector, the controller controlling the operation of the moving mechanism to move the catheter to the predetermined location, according to the position and according to a topological representation of at least a portion of the lumen system.
摘要翻译：用于将导管引导通过患者身体的管腔系统到管腔系统内的预定位置的系统，所述系统包括医疗定位系统，与导管联接的移动机构，以及与医疗定位系统并且通过移动机构，医疗定位系统包括至少一个位置检测器，位置检测器牢固地附接到导管的远端部分，医疗定位系统确定位置检测器的位置，控制器控制移动机构，以根据位置和根据管腔系统的至少一部分的拓扑表示将导管移动到预定位置。

7. 发明授权

US10398345B2 Method and system to reposition an imager based on the orientation of a medical intervention device 有权
公开(公告)号：US10398345B2
公开(公告)日：2019-09-03
申请号：US13017814
申请日：2011-01-31
申请人： Gera Strommer , Uzi Eichler
发明人： Gera Strommer , Uzi Eichler
IPC分类号： A61B5/055 , A61B5/06 , A61B5/00 , A61N5/10 , A61B34/20 , G06T7/33 , A61B34/00 , A61B90/00
摘要： System for registering a first image with a second image, the system including a first medical positioning system for detecting a first position and orientation of the body of a patient, a second medical positioning system for detecting a second position and orientation of the body, and a registering module coupled with a second imager and with the second medical positioning system, the first medical positioning system being associated with and coupled with a first imager, the first imager acquiring the first image from the body, the first imager producing the first image by associating the first image with the first position and orientation, the second medical positioning system being associated with and coupled with the second imager, the second imager acquiring the second image and associating the second image with the second position and orientation, the registering module registering the first image with the second image, according to the first position and orientation and the second position and orientation.

8. 发明授权

US09572519B2 Method and apparatus for invasive device tracking using organ timing signal generated from MPS sensors 有权
标题翻译：使用从MPS传感器生成的器官定时信号进行侵入性设备跟踪的方法和装置
公开(公告)号：US09572519B2
公开(公告)日：2017-02-21
申请号：US10986567
申请日：2004-11-10
申请人： Itzhak Shmarak , Gera Strommer , Uzi Eichler
发明人： Itzhak Shmarak , Gera Strommer , Uzi Eichler
IPC分类号： A61B5/05 , A61B5/11 , A61B5/06 , A61B8/02 , A61B5/0456 , A61B5/08 , A61B5/00 , A61B6/12 , A61B6/00 , A61B8/08 , A61B8/00 , A61B17/00 , A61N5/10
CPC分类号： A61B34/20 , A61B5/0456 , A61B5/06 , A61B5/061 , A61B5/066 , A61B5/0816 , A61B5/11 , A61B5/1102 , A61B5/1107 , A61B5/1128 , A61B5/113 , A61B5/7207 , A61B5/721 , A61B5/7275 , A61B5/7289 , A61B5/742 , A61B6/032 , A61B6/037 , A61B6/12 , A61B6/503 , A61B6/504 , A61B6/527 , A61B6/541 , A61B6/547 , A61B8/02 , A61B8/0833 , A61B8/0841 , A61B8/0883 , A61B8/0891 , A61B8/12 , A61B8/4245 , A61B8/4254 , A61B8/5276 , A61B34/10 , A61B34/25 , A61B90/10 , A61B90/36 , A61B2017/00699 , A61B2017/00703 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/2065 , A61B2034/2072 , A61B2034/256 , A61B2090/364 , A61B2090/365 , A61B2090/367 , A61B2090/372 , A61B2090/378 , A61B2090/3958 , A61B2505/05 , A61N5/1067 , G06F19/00
摘要： Apparatus for generating an organ timing signal relating to an inspected organ within the body of a patient, including a medical positioning system, and a processor The medical positioning system includes at least one reference electromagnetic transducer placed at a reference location, at least one inner electromagnetic transducer attached to a surgical tool inserted in a blood vessel in the vicinity of the inspected organ, and a medical positioning system processor coupled with the transducers. The medical positioning system processor generates medical positioning system data sets, each of which includes a collection of three-dimensional position coordinate readings demonstrating the motion trajectory of the surgical tool over time, the processor generating the organ timing signal from the data sets by detecting and identifying periodic motion frequencies in the data sets, and filtering the periodic motion frequencies from the data sets.
摘要翻译：用于产生与包括医疗定位系统在内的患者身体内的被检查器官相关的器官定时信号的设备和处理器医疗定位系统包括放置在参考位置处的至少一个参考电磁换能器，至少一个内部电磁附接到插入被检查器官附近的血管中的手术工具的传感器，以及与换能器耦合的医疗定位系统处理器。医疗定位系统处理器生成医疗定位系统数据集，每个医疗定位系统数据集包括三维位置坐标读数的集合，其显示手术工具随时间的运动轨迹，该处理器通过检测和/ 识别数据集中的周期运动频率，以及从数据集过滤周期运动频率。

9. 发明授权

US08676300B2 Method and system for navigating through an occluded tubular organ 有权
标题翻译：通过封闭的管状器官导航的方法和系统
公开(公告)号：US08676300B2
公开(公告)日：2014-03-18
申请号：US11856415
申请日：2007-09-17
申请人： Gera Strommer , Uzi Eichler , Adrian Herscovici
发明人： Gera Strommer , Uzi Eichler , Adrian Herscovici
IPC分类号： A61B6/00
CPC分类号： A61B5/06 , A61B6/12 , A61B6/466 , A61B6/481 , A61B6/487 , A61B6/503 , A61B6/504 , A61B6/5217 , A61B6/5235 , A61B6/5247 , A61B6/541 , A61B6/547 , G06K9/32 , G06K2209/057 , G06T7/564 , G06T7/596 , G06T7/60 , G06T7/73 , G06T17/00 , G06T19/003 , G06T2207/10121 , G06T2207/20044 , G06T2207/30048 , G06T2207/30101
摘要： A method generates a three dimensional (3D) model of a tubular organ having an occluded segment. The occluded segment adjoins a proximal segment at a proximal end thereof, and a distal segment at a distal end thereof. The procedures included injecting a first dye injection into the tubular organ, the first dye approaching a first end of the occluded segment. Multiple first-injection two-dimensional (2D) images of the tubular organ are acquired, each acquired from a different perspective, the first-injection 2D images further acquired with a respective organ timing signal reading. A second dye is injected into the tubular organ, the second dye approaching a second end of the occluded segment. Multiple second-injection 2D images are acquired of the tubular organ, each acquired from a different perspective, the second-injection 2D images further acquired with a respective organ timing signal reading. Superimposed 2D images are generated, one for each of the perspectives, each of the superimposed 2D images including the proximal segment and the distal segment. The boundary regions of the proximal segment and the distal segment in the superimposed 2D images are determined. The boundary regions of the occluded segment in the superimposed 2D images are determined by interpolating between the boundary regions of the proximal segment and the distal segment. A 3D model of the tubular organ from the superimposed 2D images is generated and a 3D center line of the tubular organ is determined, the 3D center line passing through the proximal segment, through the occluded segment and through the distal segment.
摘要翻译：一种方法产生具有闭塞段的管状器官的三维（3D）模型。闭塞段在其近端处邻近近端段，并且其远端处的远侧段。所述方法包括将第一染料注射注射到管状器官中，第一染料接近封闭片段的第一端。获取管状器官的多次第一次注射二维（2D）图像，每个从不同的角度获取，用相应的器官定时信号读取进一步获取的第一次注射的2D图像。将第二种染料注射到管状器官中，第二种染料接近闭塞段的第二端。从不同的角度获取管状器官的多次第二次注射2D图像，用相应的器官定时信号读取进一步获取的第二次注射2D图像。产生叠加的2D图像，每个透视图一个，叠加的2D图像中的每一个包括近端段和远端段。确定叠加2D图像中近端段和远端段的边界区域。通过在近端段和远侧段的边界区域之间进行插值来确定叠加的2D图像中的闭塞段的边界区域。产生来自叠加的2D图像的管状器官的3D模型，并且确定管状器官的3D中心线，3D中心线通过近端段，穿过闭塞段并通过远端段。

10. 发明申请

US20130184569A1 Method for producing an electrophysiological map of the heart 有权
标题翻译：产生心脏电生理图的方法
公开(公告)号：US20130184569A1
公开(公告)日：2013-07-18
申请号：US13783544
申请日：2013-03-04
申请人： Gera Strommer , Uzi Eichler , Liat Schwartz , Amit Cohen , Itay Kariv
发明人： Gera Strommer , Uzi Eichler , Liat Schwartz , Amit Cohen , Itay Kariv
IPC分类号： A61B5/06 , A61B8/13 , A61B8/08 , A61B5/0205 , A61B6/00 , A61B5/042 , A61B8/00 , A61B6/03 , A61B5/00
CPC分类号： A61B5/0044 , A61B5/0073 , A61B5/0075 , A61B5/0205 , A61B5/042 , A61B5/062 , A61B5/066 , A61B5/6852 , A61B5/6885 , A61B5/72 , A61B5/7425 , A61B5/743 , A61B6/032 , A61B6/037 , A61B6/12 , A61B6/463 , A61B6/466 , A61B6/485 , A61B6/487 , A61B6/503 , A61B6/5205 , A61B6/5288 , A61B8/0841 , A61B8/0883 , A61B8/13 , A61B8/463 , A61B8/466 , A61B8/483 , A61B8/5207 , A61B8/5284 , G06F19/00 , G16H50/50
摘要： Methods and systems for producing an electrophysiological map of a heart of a patient are disclosed. An example method may include determining a target location and an orientation of a catheter tip, confirming that the tip is located at the target location, measuring the heart parameter value at each of the target locations, and superimposing a plurality of representations of the heart parameter value. Confirmation that the tip of the catheter is located at a target location can be accomplished by comparing the current location of the tip with the target location, a corresponding heart parameter value being measured at each of the target locations by a heart parameter sensor, and the representations of the heart parameter value being superimposed on an image of the heart at the target location to produce the electrophysiological map.
摘要翻译：公开了用于产生患者心脏的电生理图的方法和系统。示例性方法可以包括确定导管尖端的目标位置和取向，确认尖端位于目标位置，测量每个目标位置处的心脏参数值，以及叠加心脏参数的多个表示值。确认导管的尖端位于目标位置可以通过将尖端的当前位置与目标位置进行比较来完成，通过心脏参数传感器在每个目标位置处测量相应的心脏参数值，并且将心脏参数值的表示叠加在目标位置的心脏图像上以产生电生理图。

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