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1. 发明申请

US20190247146A1 Working Length Confirmation Utilizing Negative Pressure Irrigating Technique And Handpiece 审中-公开
公开(公告)号：US20190247146A1
公开(公告)日：2019-08-15
申请号：US15894860
申请日：2018-02-12
申请人： Saju Joseph George , George Vijay Joseph , Sanjay Jacob George
发明人： Saju Joseph George , George Vijay Joseph , Sanjay Jacob George
IPC分类号： A61C5/40 , A61C17/02 , A61C1/08 , A61C1/05 , A61C1/00 , A61C5/50
CPC分类号： A61C5/40 , A61C1/0092 , A61C1/052 , A61C1/088 , A61C5/50 , A61C17/0202 , A61C17/0208
摘要： The invention relates to a handpiece for simultaneously irrigating and suctioning during an endodontic procedure, the handpiece comprising a handle portion comprising a first fluid line and a second fluid line passing into a head portion comprising an outlet for the first fluid line and an inlet for the second fluid line. The invention also relates to a method of performing a dental procedure such as a root canal. The handpiece permits the procedure of irrigating, cleansing and disinfection to be conducted by a single operator such as an endodontist, a dentist or even a dental student.

2. 发明授权

US09376435B2 Chromophores for the detection of volatile organic compounds 有权
标题翻译：用于检测挥发性有机化合物的发色团
公开(公告)号：US09376435B2
公开(公告)日：2016-06-28
申请号：US13489876
申请日：2012-06-06
申请人： Subi Jacob George , Mohit Kumar
发明人： Subi Jacob George , Mohit Kumar
IPC分类号： G01N21/64 , C07D471/06
CPC分类号： C07D471/06 , G01N21/6428 , G01N21/783 , G01N31/224 , G01N2021/6439
摘要： Aromatic diimide chromophores and methods for using the chromophores for the detection of volatile organic compounds are described. The chromophores are able to reversibly change colors in the presence or absence of volatile organic compounds.
摘要翻译：描述了芳族二酰亚胺发色团和使用发色团检测挥发性有机化合物的方法。在存在或不存在挥发性有机化合物的情况下，发色团能够可逆地改变颜色。

3. 发明授权

US08501715B2 Oxidized lipids and uses thereof in the treatment of inflammatory diseases and disorders 有权
公开(公告)号：US08501715B2
公开(公告)日：2013-08-06
申请号：US13085542
申请日：2011-04-13
申请人： Dror Harats , Jacob George , Gideon Halperin , Itzhak Mendel , Niva Yacov , Eti Kovalevski-Ishai
发明人： Dror Harats , Jacob George , Gideon Halperin , Itzhak Mendel , Niva Yacov , Eti Kovalevski-Ishai
IPC分类号： A61K31/66 , C07F9/02
CPC分类号： C07F9/106 , A61K31/075 , A61K31/08 , A61K31/11 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/225 , A61K31/24 , A61K31/685 , C07C43/13 , C07C43/1785 , C07C43/1787 , C07F9/10 , Y02A50/411 , Y02A50/414
摘要： Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.

4. 发明申请

US20120195329A1 HYBRID WIRELESS/WIRED RoF TRANSPONDER AND HYBRID RoF COMMUNICATION SYSTEM USING SAME 有权
标题翻译：混合无线/有线RoF TRANSPONDER和混合RoF通信系统
公开(公告)号：US20120195329A1
公开(公告)日：2012-08-02
申请号：US13439996
申请日：2012-04-05
申请人： Dean Michael Thelen , Jacob George , Luis Alberto Zenteno , Michael Sauer , Martyn N. Easton
发明人： Dean Michael Thelen , Jacob George , Luis Alberto Zenteno , Michael Sauer , Martyn N. Easton
IPC分类号： H04B10/12 , H04B10/10 , H04J1/00
CPC分类号： H04B10/25752
摘要： A radio-over-fiber (RoF) hybrid wired/wireless transponder is disclosed that is configured to provide both wireless and wired communication between a hybrid head-end and one or more client devices. The hybrid transponder includes optical-to-electrical (O/E) and electrical-to-optical (E/O) conversion capability and is configured to frequency multiplex/demultiplex electrical “wired” signals and electrical “wireless” signals. The electrical wireless signals are wirelessly communicated to the client device(s) via a multiple-input/multiple-output (MIMO) antenna system within a cellular coverage area. The electrical wired signals are communicated to the client device(s) via a wireline cable that plugs into a wireline cable port on the transponder. The hybrid RoF system includes a hybrid head-end capable of transmitting and receiving wired and wireless optical signals, and an optical fiber cable that is optically coupled to the hybrid head-end and to at least one hybrid transponder. Drop-down transponder configurations that allow for easy wired and wireless connectivity between the client device(s) to the transponder(s) are also disclosed.
摘要翻译：公开了一种无线电光纤（RoF）混合有线/无线应答器，其被配置为在混合头端和一个或多个客户端设备之间提供无线和有线通信。混合转发器包括光电（O / E）和电 - 光（E / O）转换能力，并且被配置为频率复用/解复用电“有线”信号和电“无线”信号。无线电信号通过蜂窝覆盖区域内的多输入/多输出（MIMO）天线系统无线地传送到客户端设备。电接线信号通过有线电缆传送到客户端设备，该有线电缆插入应答器上的有线电缆端口。混合RoF系统包括能够发送和接收有线和无线光信号的混合头端，以及光耦合到混合头端和至少一个混合转发器的光纤电缆。还公开了允许在客户端设备与应答器之间简单的有线和无线连接的下拉式应答器配置。

5. 发明授权

US08175459B2 Hybrid wireless/wired RoF transponder and hybrid RoF communication system using same 有权
标题翻译：混合无线/有线RoF转发器和使用它的混合RoF通信系统
公开(公告)号：US08175459B2
公开(公告)日：2012-05-08
申请号：US11974226
申请日：2007-10-12
申请人： Dean Michael Thelen , Jacob George , Luis Alberto Zenteno , Michael Sauer , Martyn N. Easton
发明人： Dean Michael Thelen , Jacob George , Luis Alberto Zenteno , Michael Sauer , Martyn N. Easton
IPC分类号： H04B10/00
CPC分类号： H04B10/25752
摘要： A radio-over-fiber (RoF) hybrid wired/wireless transponder is disclosed that is configured to provide both wireless and wired communication between a hybrid head-end and one or more client devices. The hybrid transponder includes optical-to-electrical (O/E) and electrical-to-optical (E/O) conversion capability and is configured to frequency multiplex/demultiplex electrical “wired” signals and electrical “wireless” signals. The electrical wireless signals are wirelessly communicated to the client device(s) via a multiple-input/multiple-output (MIMO) antenna system within a cellular coverage area. The electrical wired signals are communicated to the client device(s) via a wireline cable that plugs into a wireline cable port on the transponder. The hybrid RoF system includes a hybrid head-end capable of transmitting and receiving wired and wireless optical signals, and an optical fiber cable that is optically coupled to the hybrid head-end and to at least one hybrid transponder. Drop-down transponder configurations that allow for easy wired and wireless connectivity between the client device(s) to the transponder(s) are also disclosed.
摘要翻译：公开了一种无线电光纤（RoF）混合有线/无线应答器，其被配置为在混合头端与一个或多个客户端设备之间提供无线和有线通信。混合转发器包括光电（O / E）和电 - 光（E / O）转换能力，并且被配置为频率复用/解复用电“有线”信号和电“无线”信号。无线电信号通过蜂窝覆盖区域内的多输入/多输出（MIMO）天线系统无线地传送到客户端设备。电接线信号通过有线电缆传送到客户端设备，该有线电缆插入应答器上的有线电缆端口。混合RoF系统包括能够发送和接收有线和无线光信号的混合头端，以及光耦合到混合头端和至少一个混合转发器的光纤电缆。还公开了允许在客户端设备与应答器之间简单的有线和无线连接的下拉式应答器配置。

6. 发明申请

US20120105208A1 TRANSPONDER SYSTEMS AND METHODS FOR RADIO-OVER-FIBER (RoF) WIRELESS PICOCELLULAR SYSTEMS 审中-公开
标题翻译：无线光纤（RoF）无线光纤系统的传输系统和方法
公开(公告)号：US20120105208A1
公开(公告)日：2012-05-03
申请号：US13342468
申请日：2012-01-03
申请人： Jacob George , Michael Sauer , Andrey Kobyakov , William Carl Hurley
发明人： Jacob George , Michael Sauer , Andrey Kobyakov , William Carl Hurley
IPC分类号： G06K7/01
CPC分类号： G06K19/0723 , G06K7/10178 , H04B10/25756 , H04W88/085
摘要： Transponder systems and methods for radio-over-fiber (RoF) wireless picocellular system are disclosed. One type of transponder system includes a RoF transponder used in combination with at least one radiation-reflector assembly to provide for enhanced antenna directivity of the transponder. Another type of transponder system is a transponder node assembly, wherein two or more transponders are integrated into a single assembly, thereby reducing cost while facilitating RoF wireless picocellular system deployment. Another type of transponder system provides one or more transponders in a RoF wireless picocellular system with radio-frequency identification (RFID) tags, and uses an RFID tag reader to locate and read information from the transponders, as well as to perform transponder mode selection. Another type of transponder system is directed to a tether cable assembly that includes a dispensible/retractable coiled tether cable housed in a protective housing for connecting the tether cable to a transponder.
摘要翻译：公开了用于无线电光纤（RoF）无线微微蜂窝系统的应答器系统和方法。一种类型的应答器系统包括与至少一个辐射 - 反射器组合组合使用的RoF应答器，以提供应答器的增强的天线方向性。另一种类型的应答器系统是应答器节点组件，其中将两个或更多个应答器集成到单个组件中，从而在促进RoF无线微微蜂窝系统部署的同时降低成本。另一种类型的应答器系统在具有射频识别（RFID）标签的RoF无线微微蜂窝系统中提供一个或多个转发器，并且使用RFID标签读取器来定位和读取来自应答器的信息，以及执行应答器模式选择。另一类型的应答器系统被引导到系绳电缆组件，其包括容纳在用于将系绳电缆连接到应答器的保护壳体中的可分配/可伸缩线圈系绳。

7. 发明申请

US20110280832A1 EOTAXIN-2 (CCL24) INHIBITORS IN INFLAMMATORY, AUTOIMMUNE, AND CARDIOVASCULAR DISORDERS 有权
标题翻译： EOTAXIN-2（CCL24）抑制剂在炎症，自发性和心脏血管疾病中的作用
公开(公告)号：US20110280832A1
公开(公告)日：2011-11-17
申请号：US13146711
申请日：2010-01-28
申请人： Jacob George , Gad Keren
发明人： Jacob George , Gad Keren
IPC分类号： A61K39/395 , A61K38/19 , A61K38/02 , A61K38/13 , A61K38/21 , C07K16/24 , C07H21/04 , A61P29/00 , A61P37/00 , A61P19/02 , A61P9/00 , A61P9/10 , A61P1/00 , A61P3/10 , A61P25/00 , A61P31/00 , C12N15/63 , C12N5/16 , C12N5/10 , C12N1/21 , A61K31/7088
CPC分类号： C07K16/24 , A61K38/13 , A61K38/215 , A61K2039/505 , A61K2300/00
摘要： The presently described subject matter is based on the finding that inhibition of eotaxin-2 by polyclonal or monoclonal antibodies, has a significant protective effect in animal models of inflammatory diseases such as rheumatoid arthritis, experimental autoimmune encephalomyelitis (EAE), colitis, diabetes, and atherosclerosis. Thus, provided are pharmaceutical compositions including specific anti-eotaxin 2 antibodies for use alone or in combination with other therapeutic agents in the treatment of inflammatory, autoimmune and cardiovascular diseases. Also provided are specific anti-eotaxin-2 monoclonal antibodies, and methods of treatment utilizing such antibodies.
摘要翻译：目前描述的主题是基于以下发现：通过多克隆或单克隆抗体抑制嗜酸性粒细胞趋化因子-2在诸如类风湿性关节炎，实验性自身免疫性脑脊髓炎（EAE），结肠炎，糖尿病和炎性疾病的动物模型的动物模型中具有显着的保护作用动脉粥样硬化。因此，提供了药物组合物，其包括单独使用或与其它治疗剂组合用于治疗炎性，自身免疫性和心血管疾病的特异性抗 - 嗜酸性粒细胞趋化因子2抗体。还提供特异性抗 - 嗜酸性粒细胞趋化因子-2单克隆抗体，以及利用这种抗体的治疗方法。

8. 发明授权

US08020314B2 Methods and apparatus for drying ceramic green bodies with microwaves 有权
标题翻译：用微波干燥陶瓷生坯体的方法和装置
公开(公告)号：US08020314B2
公开(公告)日：2011-09-20
申请号：US12262902
申请日：2008-10-31
申请人： Jacob George , Parasuram Padmanabhan Harihara , Min Shen
发明人： Jacob George , Parasuram Padmanabhan Harihara , Min Shen
IPC分类号： F26B11/03
CPC分类号： H05B6/78 , B28B11/241 , B28B11/243 , C04B2235/606 , F26B3/347 , F26B2210/02 , H05B6/6447 , H05B2206/046 , Y02P40/63
摘要： Methods and apparatus for drying ceramic green bodies include providing one or more ceramic green bodies in a microwave heating chamber operatively connected to a microwave source and a PLC. The total mass of the ceramic green bodies present in the microwave heating chamber is determined. Microwave energy is generated with the microwave source and transmitted from the microwave source to the microwave heating chamber. A transmitted power of the microwave energy transmitted from the microwave source to the microwave heating chamber is measured with power sensors. The reflected power of reflected microwave energy reflected back from the microwave heating chamber is also measured. The power of the microwave energy transmitted from the microwave source to the microwave heating chamber is adjusted based on the total mass of ceramic green bodies present in the microwave heating chamber, the measured transmitted power and the measured reflected power.
摘要翻译：用于干燥陶瓷生坯体的方法和装置包括在可操作地连接到微波源和PLC的微波加热室中提供一个或多个陶瓷生坯体。确定存在于微波加热室中的陶瓷生坯的总质量。微波能量由微波源产生并从微波源传输到微波加热室。使用功率传感器测量从微波源传输到微波加热室的微波能量的发射功率。还测量了从微波加热室反射回来的反射微波能量的反射功率。基于微波加热室中存在的陶瓷生坯的总质量，测量的透射功率和测量的反射功率，调节从微波源传输到微波加热室的微波能量的功率。

9. 发明申请

US20110116794A1 Radio-Over-Fiber (RoF) System for Protocol-Independent Wired and/or Wireless Communication 有权
标题翻译：用于无协议无线和/或无线通信的无线光纤（RoF）系统
公开(公告)号：US20110116794A1
公开(公告)日：2011-05-19
申请号：US12618613
申请日：2009-11-13
申请人： Jacob George , Michael Sauer , Dean M. Thelen
发明人： Jacob George , Michael Sauer , Dean M. Thelen
IPC分类号： H04J14/00
CPC分类号： H04B10/25751 , H04B10/25754 , H04N7/15 , H04Q11/0067 , H04W16/26 , H04W76/10 , H04W84/12 , H04W88/08 , H04W88/085 , H04W92/20
摘要： An optically-switched fiber optic communication system, such as a Radio-over-Fiber (RoF) based optical fiber link system, may be used to increase the range of peer-to-peer communications. The optically-switched fiber optic communication system may include a head-end unit (HEU) having an optical switch bank. Fiber optic cables comprising optical fibers optically couple the HEU to one or more remote access points in different coverage areas. The optical switch bank in the HEU provides a link between the remote access points in the different coverage areas such that devices in the different cellular coverage areas can communicate with each other over the optical fibers through the HEU. By using the optically-switched fiber optic communication system, the range and coverage of communication between devices may be extended such that devices in different coverage areas and devices using different communication protocols can communicate.
摘要翻译：可以使用诸如基于光纤无线光纤链路系统的光交换光纤通信系统来增加对等通信的范围。光交换光纤通信系统可以包括具有光开关组的头端单元（HEU）。包含光纤的光纤光缆将HEU光学地耦合到不同覆盖区域中的一个或多个远程接入点。 HEU中的光开关组提供不同覆盖区域中的远程接入点之间的链路，使得不同蜂窝覆盖区域中的设备可以通过HEU通过光纤彼此通信。通过使用光交换光纤通信系统，可以扩展设备之间的通信的范围和覆盖范围，使得不同覆盖区域中的设备和使用不同通信协议的设备可以通信。

10. 发明授权

US07902176B2 Oxidized lipids and uses thereof in the treatment of inflammatory diseases and disorders 有权
公开(公告)号：US07902176B2
公开(公告)日：2011-03-08
申请号：US10567543
申请日：2004-05-27
申请人： Dror Harats , Jacob George , Gideon Halperin , Niva Yacov , Eti Kovalevski-Ishai
发明人： Dror Harats , Jacob George , Gideon Halperin , Niva Yacov , Eti Kovalevski-Ishai
IPC分类号： A61K31/66 , C07F9/02
CPC分类号： C07F9/106 , A61K31/075 , A61K31/08 , A61K31/11 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/225 , A61K31/24 , A61K31/685 , C07C43/13 , C07C43/1785 , C07C43/1787 , C07F9/10 , Y02A50/411 , Y02A50/414
摘要： Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.

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