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1. 发明授权

US06993373B2 Invasive device provided with a segmented electrical connection conductor 失效
标题翻译：具有分段电连接导体的有创装置
公开(公告)号：US06993373B2
公开(公告)日：2006-01-31
申请号：US09990208
申请日：2001-11-21
申请人： Johan Ernst Willy Vrijheid , Johannes Jacobus Van Vaals
发明人： Johan Ernst Willy Vrijheid , Johannes Jacobus Van Vaals
IPC分类号： A61B5/055
CPC分类号： G01R33/285 , A61N1/05 , A61N1/086 , A61N1/3718
摘要： An invasive device 17, such as a catheter, is connected to a supply and control unit via a connection conductor 21 for the transfer of power supply energy and/or LF signals to and from an electrical circuit 20 in the distal part 18 of the device. During operation the connection conductor traverses the homogeneous magnetic field and the RF field of the MRI apparatus; this may give rise to heating of the connection conductor and/or to a disturbance of said fields. In order to mitigate these drawbacks, the connection conductor in accordance with the invention is subdivided into mutually separated segments 22-i, each of which is much shorter (for example, 1/20) than the wavelength of the RE field in the apparatus; the segments are separated from one another by separating elements 23-i (self-inductances) that provide a high inductance for said RF frequencies and a low inductance for comparatively low frequencies.
摘要翻译：诸如导管的侵入性装置17经由连接导体21连接到供电和控制单元，用于将电力能量和/或LF信号传送到设备的远端部分18中的电路20和从该电路20的远端部分18中的电路20传送。。在运行期间，连接导体穿过MRI装置的均匀磁场和RF场; 这可能导致连接导体的加热和/或导致所述场的干扰。为了减轻这些缺点，根据本发明的连接导体被细分成彼此分开的部分22i，每个部分22 -i比设备中的RE场的波长短得多（例如1/20）通过对于所述RF频率提供高电感的分离元件23 -i（自感）和相对低频的低电感，所述段彼此分离。

2. 发明授权

US06768917B1 Magnetic resonance imaging method and system 失效
标题翻译：磁共振成像方法及系统
公开(公告)号：US06768917B1
公开(公告)日：2004-07-27
申请号：US09857310
申请日：2001-06-01
申请人： Johannes Jacobus Van Vaals
发明人： Johannes Jacobus Van Vaals
IPC分类号： A61B505
CPC分类号： A61B5/055 , G01R33/54
摘要： A method of forming a magnetic resonance image involves separate measurement of the position of a measuring site. The magnetic resonance image is corrected on the basis of the measured position of the measuring site.
摘要翻译：形成磁共振图像的方法包括单独测量测量位置的位置。基于测量位置的测量位置来校正磁共振图像。

3. 发明授权

US06731969B2 Magnetic resonance method, apparatus and computer program product 失效
标题翻译：磁共振方法，仪器和计算机程序产品
公开(公告)号：US06731969B2
公开(公告)日：2004-05-04
申请号：US09966402
申请日：2001-09-28
申请人： Johannes Jacobus Van Vaals , Frederik Visser
发明人： Johannes Jacobus Van Vaals , Frederik Visser
IPC分类号： A61B5055
CPC分类号： G01R33/561 , G01R33/28 , G01R33/56308
摘要： A magnetic resonance method for forming a fast dynamic image from a plurality of signals of an RF probe is described. The RF probe is moved relative to an object to be imaged so as to acquire at least two adjacent Fields-of-View (FOV) which are reconstructed so as to form an image of a region of interest which includes both FOVs. The object to be imaged is scanned by a moving RF antenna. Furthermore, the first FOV is centered at the initial probe position and after each subsequent scan the position of the imaging field within the actual FOV is determined. From that data the next position of the RF probe relative to the object is computed and, if the imaging field runs out of the actual FOV, the RF antenna is moved to the estimated next position of the RF probe so that the subsequent FOV is centered again at the RF probe position. A composite image is then generated from the successive images of the various adjacent FOVs.
摘要翻译：描述了用于从RF探针的多个信号形成快速动态图像的磁共振方法。 RF探针相对于要被成像的物体移动，以获得至少两个相邻的视场（FOV），其被重构以形成包括两个FOV的感兴趣区域的图像。要被成像的物体被移动的RF天线扫描。此外，第一FOV以初始探针位置为中心，并且在每次后续扫描之后，确定在实际FOV内的成像场的位置。根据该数据计算RF探针相对于物体的下一个位置，并且如果成像场用完实际FOV，则将RF天线移动到RF探测器的估计的下一个位置，以便随后的FOV居中再次在RF探针位置。然后从各种相邻FOV的连续图像生成合成图像。

4. 发明授权

US07123007B2 MR image reconstruction 失效
公开(公告)号：US07123007B2
公开(公告)日：2006-10-17
申请号：US09995439
申请日：2001-11-27
申请人： Ulrich Katscher , Johannes Jacobus Van Vaals
发明人： Ulrich Katscher , Johannes Jacobus Van Vaals
IPC分类号： G01V3/00
CPC分类号： G01R33/5611 , G01R33/4835 , G01R33/56509
摘要： The invention relates to an MR imaging method in which the parallel acquisition of the MR data, for example in conformity with the SMASH or SENSE methods, is performed by means of a plurality of receiving coils. The different spatial sensitivity profiles of the receiving coils are used for the image reconstruction. When the sensitivity data used during the image reconstruction do not correspond to the position in space of the receiving coils during the image acquisition, undesirable image artifacts will occur. In accordance with the invention such artifacts are eliminated by (virtually) adapting the spatial sensitivity profiles automatically during the image reconstruction.

5. 发明授权

US06687529B2 Method of acquiring images of a plane in a magnetic resonance apparatus and magnetic resonance apparatus suitable for carrying out such a method 失效
标题翻译：在磁共振装置中获取平面图像的方法以及适于实施这种方法的磁共振装置
公开(公告)号：US06687529B2
公开(公告)日：2004-02-03
申请号：US09942013
申请日：2001-08-29
申请人： Johannes Jacobus Van Vaals
发明人： Johannes Jacobus Van Vaals
IPC分类号： A61B5055
CPC分类号： G01R33/4833
摘要： In a method for acquiring an image of a plane in a magnetic resonance apparatus, the images are obtained in imaging planes which are defined directly with respect to the patient. The magnetic resonance apparatus includes an imaging volume, a patient support table which positioned in the imaging volume, a position measuring device to establish and maintain in real time the position of the patient, as well as a controller for controlling gradient coils in response to the signals provided by the position measuring device in such a manner that consecutive images are acquired from imaging planes which are defined directly with respect to the patient.
摘要翻译：在用于获取磁共振装置中的平面图像的方法中，在针对患者直接定义的成像平面中获得图像。磁共振装置包括成像体积，位于成像体积中的患者支撑台，位置测量装置，用于实时建立和维持患者的位置，以及控制器，用于响应于所述成像体积控制梯度线圈由位置测量装置提供的信号，使得从相对于患者直接定义的成像平面获取连续的图像。

6. 发明授权

US06675416B2 Head support for interventional MR 有权
标题翻译：主要支持介入性MR
公开(公告)号：US06675416B2
公开(公告)日：2004-01-13
申请号：US09837939
申请日：2001-04-19
申请人： Frederik Visser , Johannes Jacobus Van Vaals , Bartholomeus Muskens
发明人： Frederik Visser , Johannes Jacobus Van Vaals , Bartholomeus Muskens
IPC分类号： A61G1300
CPC分类号： A61G13/121 , A61B5/0555 , A61B6/0421 , A61B90/14 , A61G7/072 , A61G15/125
摘要： In interventional MRI, for example, in neurosurgical applications, the head of a patient must be positioned on a head support while allowing reproducible manipulation of the head. The head support must be made of a material that is compatible with MR. Furthermore, spatial restrictions imposed by the bore of the magnetic resonance apparatus have to be dealt with. The head support in accordance with the invention includes a support whereon the patient head or a stereotactic frame can be rested. The head support is suppored by a mounting device. Both the support and mounting device are fixed on the table top. The mounting device provides a sliding surface that enables rotation of the support relative to the mounting device. The support can be curved towards the table top thus providing a concave surface so as to lower the supporting surface for a stereotactic frame and hence to minimize the total volume of the construction. When a radius of between 10 cm and 18 cm is chosen for the sliding surface, the patient will not suffer from stress to the cervical vertebrae during rotation of the supporting means. The reproducibility of the patient positioning with respect to the head support is thus improved, since it is not necessary to reposition the patient after each rotation so as to reduce the induced stress.
摘要翻译：在介入MRI中，例如，在神经外科应用中，患者的头部必须位于头部支撑件上，同时允许头部的可重复操纵。头部支撑必须由与MR兼容的材料制成。此外，必须处理由磁共振装置的孔施加的空间限制。根据本发明的头部支撑件包括其上可以搁置患者头部或立体定向框架的支撑件。头部支撑件由安装装置支撑。支撑和安装装置都固定在桌面上。安装装置提供滑动表面，其使得支撑件能够相对于安装装置旋转。支撑件可以朝向台面弯曲，从而提供凹形表面，以便降低立体定向框架的支撑表面，从而使结构的总体积最小化。当滑动表面选择10厘米至18厘米的半径时，患者在支撑装置旋转期间不会受到颈椎的压力。因此，改善了相对于头部支撑件的患者定位的再现性，因为不需要在每次旋转之后重新定位患者以减少感应压力。

7. 发明授权

US06574493B2 Method of localizing objects in interventional radiology 有权
标题翻译：介入放射学中对象局部化的方法
公开(公告)号：US06574493B2
公开(公告)日：2003-06-03
申请号：US09792097
申请日：2001-02-23
申请人： Volker Rasche , Georg Schmitz , Jörg Sabczynski , Waldemar Zylka , Johannes Jacobus Van Vaals
发明人： Volker Rasche , Georg Schmitz , Jörg Sabczynski , Waldemar Zylka , Johannes Jacobus Van Vaals
IPC分类号： A61B505
CPC分类号： A61B6/12 , A61B34/20 , A61B90/36 , A61B90/39 , A61B2034/2065 , A61B2090/376 , A61B2090/3983
摘要： The invention relates to a method enabling the localization of objects, for example surgical instruments, in interventional radiology. The method utilizes the known geometrical shape of the object to be localized in order to simulate projections therefrom for comparison with real projection images. Optimum correspondence between simulation and real image yields the desired object position and object orientation. The invention is based on digital image processing and can be used in conjunction with customary radiological diagnostic apparatus such as C-arm fluoroscopy apparatus, computed tomography apparatus or magnetic resonance tomography apparatus. Objects to be localized can be provided with markers whose spatial position yields an unambiguous projection image.
摘要翻译：本发明涉及一种使介入放射学中的物体（例如手术器械）能够定位的方法。该方法利用被定位的已知几何形状的物体来模拟其中的投影，以与实际投影图像进行比较。模拟和实际图像之间的最佳对应可以产生所需的对象位置和对象方向。本发明基于数字图像处理，并且可以与诸如C臂荧光透视装置，计算机断层摄影装置或磁共振断层摄影装置的常规放射诊断装置结合使用。可以提供要定位的对象，其标记的空间位置产生明确的投影图像。

8. 发明授权

US08112143B2 Using magnetic resonance images for locating anatomical targets 有权
标题翻译：使用磁共振图像定位解剖目标
公开(公告)号：US08112143B2
公开(公告)日：2012-02-07
申请号：US10567200
申请日：2004-08-02
申请人： Johannes Jacobus Van Vaals
发明人： Johannes Jacobus Van Vaals
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61N5/103
摘要： A novel MR method and system is described for using MR images for planning radiotherapy treatment. The images are obtained by a scanner which generates a magnetic field with a magnetic center (isocenter). First at least one fiducial marker (4; 5) is applied to the body (1) of the patient at a predetermined distance from the isocenter. The patient is repositioned within said scanner such that an anatomical target (2) is located in close vicinity of said isocenter. A first image of said target (2) is obtained and then the patient (1) is shifted such that the fiducial marker (4; 5) is close to the isocenter. A second image is obtained at the shifted position, in which the fiducial marker has an accurate geometrical position, that is merged into said first image.
摘要翻译：描述了使用MR图像来规划放射治疗的新型MR方法和系统。这些图像通过用磁性中心（等角中心）产生磁场的扫描器获得。首先，至少一个基准标记（4; 5）以距离等角点预定距离施加到患者的身体（1）。患者在所述扫描器内重新定位，使得解剖目标（2）位于所述等角点附近。获得所述目标（2）的第一图像，然后使患者（1）移位，使得基准标记（4; 5）接近等角点。在移位位置处获得第二图像，其中基准标记具有精确的几何位置，其被合并到所述第一图像中。

9. 发明授权

US07142700B2 Geometry matching for imaging medical apparatus 失效
标题翻译：成像医疗器械的几何匹配
公开(公告)号：US07142700B2
公开(公告)日：2006-11-28
申请号：US09897364
申请日：2001-07-02
申请人： Johannes Jacobus Van Vaals
发明人： Johannes Jacobus Van Vaals
IPC分类号： G06K9/00
CPC分类号： A61B6/5235 , A61B5/0035 , A61B5/055 , A61B6/00 , A61B6/4417 , A61B6/5247
摘要： Anatomical matching of images acquired by different imaging modalities plays an important role in diagnostic medical imaging. In common medical practice such matching takes place after the acquisition of the data sets containing the information to be matched and while utilizing standard post-processing algorithms. The invention provides a method for the acquisition of anatomically matched images while using the information concerning the position and orientation of the first imaging modality relative to the object. Upon selection of a relevant image from the primary data set acquired by means of the first imaging modality, the co-ordinates which unambiguously define the position of the first imaging apparatus relative to this image are defined. These co-ordinates are made available to the second imaging modality which is adjusted in conformity therewith. The image acquired by the second imaging modality will thus be anatomatically matched with the primary image.
摘要翻译：由不同成像模式获取的图像的解剖匹配在诊断医学成像中起重要作用。在通常的医疗实践中，这种匹配在采集包含要匹配的信息的数据集之后并且在利用标准后处理算法的同时进行。本发明提供一种用于在使用关于第一成像模态相对于对象的位置和取向的信息的同时获取解剖学上匹配的图像的方法。在从通过第一成像模式获取的主要数据集中选择相关图像之后，定义了明确地定义第一成像装置相对于该图像的位置的坐标。这些坐标可用于根据其调整的第二成像模式。因此，通过第二成像模式获取的图像将与主要图像解剖学匹配。

10. 发明授权

US07027854B2 Magnetic resonance imaging utilizing a microcoil 失效
标题翻译：使用微线圈的磁共振成像
公开(公告)号：US07027854B2
公开(公告)日：2006-04-11
申请号：US09980176
申请日：2001-03-28
申请人： Miha Fuderer , Johannes Jacobus Van Vaals
发明人： Miha Fuderer , Johannes Jacobus Van Vaals
IPC分类号： A61B5/055
CPC分类号： G01R33/34084 , G01R33/287
摘要： An interventional magnetic resonance method and apparatus utilizing a microcoil which enable localization of an interventional instrument by detecting magnetic resonance signals from the surroundings of the microcoil under the influence of magnetic field gradients. The outstanding reliability and the high speed of the method are due to the application of spatially non-selective RF pulses in conjunction with a sequence of gradient pulses in non-colinear directions. The localization method can be used inter alia for angiography wherein the signal intensity is used to determine the amount of blood present in the blood vessel.
摘要翻译：一种介入磁共振方法和利用微线圈的装置，其通过在磁场梯度的影响下检测来自微线圈周围的磁共振信号来实现介入仪器的定位。该方法的突出的可靠性和高速度是由于空间非选择性RF脉冲与非共线方向上的梯度脉冲序列的应用。定位方法可以用于血管造影术，其中信号强度用于确定存在于血管中的血液量。

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