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1. 发明授权

US08788047B2 Systems and methods for the treatment of pain through neural fiber stimulation 有权
标题翻译：通过神经纤维刺激治疗疼痛的系统和方法
公开(公告)号：US08788047B2
公开(公告)日：2014-07-22
申请号：US13309107
申请日：2011-12-01
申请人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
发明人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
IPC分类号： A61N1/34 , A61N1/36
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/36017 , A61N1/36021 , A61N1/36057
摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
摘要翻译：本发明的实施方案提供了通过激活选择性神经纤维来治疗疼痛的系统和方法。神经纤维可以包含一个或多个传入神经纤维和/或一个或多个传出神经纤维。如果传入纤维被单独或与传出纤维组合刺激，则施用治疗有效量的电刺激以以接近自然传入活性的方式激活传入途径。传入纤维可能与肌肉锭，高尔基体腱器官，肌肉锭子的次要受体，关节受体，触觉受体和其他类型的机械感受器和/或本体感受器的主要受体相关联。如果传出纤维被单独或与传入纤维组合刺激，则施加治疗有效量的电刺激以激活内部和/或外部肌肉纤维，这导致与其相关联的传入纤维的间接活化。

2. 发明申请

US20120310301A1 SYSTEMS AND METHODS FOR THE TREATMENT OF PAIN THROUGH NEURAL FIBER STIMULATION 有权
公开(公告)号：US20120310301A1
公开(公告)日：2012-12-06
申请号：US13309107
申请日：2011-12-01
申请人： MARIA E. BENNETT , JOSEPH W. BOGGS, II , WARREN M. GRILL , JOHN CHAE
发明人： MARIA E. BENNETT , JOSEPH W. BOGGS, II , WARREN M. GRILL , JOHN CHAE
IPC分类号： A61N1/36 , A61N1/04
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/36017 , A61N1/36021 , A61N1/36057
摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

3. 发明申请

US20050054260A1 Doll head construction 审中-公开
标题翻译：娃娃头施工
公开(公告)号：US20050054260A1
公开(公告)日：2005-03-10
申请号：US10653970
申请日：2003-09-04
申请人： John Chae
发明人： John Chae
IPC分类号： A63H3/02 , A63H9/00 , A63H3/06
CPC分类号： A63H3/02 , A63H9/00
摘要： A doll is disclosed having a doll head with an integral foam insert, and a doll body. A mesh is coupled to an inner surface of the doll head on the foam insert. The doll body is coupled to the doll head by sewing the doll body to the doll head with stitches that extend through the mesh and the foam insert.
摘要翻译：公开了一种具有整体泡沫插入物的玩偶头部和玩偶主体的娃娃。网状物连接到泡沫插入件上的玩偶头部的内表面。娃娃身体通过将娃娃身体缝合到玩偶头部，并通过网状物和泡沫插入物延伸的针迹与娃娃头部相连。

4. 发明申请

US20120310314A1 SYSTEMS AND METHODS FOR THE TREATMENT OF PAIN THROUGH NEURAL FIBER STIMULATION 有权
标题翻译：通过神经纤维刺激治疗疼痛的系统和方法
公开(公告)号：US20120310314A1
公开(公告)日：2012-12-06
申请号：US13309024
申请日：2011-12-01
申请人： Maria E. BENNETT , Joseph W. BOGGS, II , Warren M. GRILL , John CHAE
发明人： Maria E. BENNETT , Joseph W. BOGGS, II , Warren M. GRILL , John CHAE
IPC分类号： A61N1/04
CPC分类号： A61N1/36071 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36057
摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
摘要翻译：本发明的实施方案提供了通过激活选择性神经纤维来治疗疼痛的系统和方法。神经纤维可以包含一个或多个传入神经纤维和/或一个或多个传出神经纤维。如果传入纤维被单独或与传出纤维组合刺激，则施用治疗有效量的电刺激以以接近自然传入活性的方式激活传入途径。传入纤维可能与肌肉锭，高尔基体腱器官，肌肉锭子的次要受体，关节受体，触觉受体和其他类型的机械感受器和/或本体感受器的主要受体相关联。如果传出纤维被单独或与传入纤维组合刺激，则施加治疗有效量的电刺激以激活内部和/或外部肌肉纤维，这导致与其相关联的传入纤维的间接活化。

5. 发明授权

US08886337B2 System and method for treating shoulder pain related to subacromial impingement syndrome 有权
标题翻译：治疗肩峰疼痛与肩峰下冲击综合征相关的系统和方法
公开(公告)号：US08886337B2
公开(公告)日：2014-11-11
申请号：US13991033
申请日：2011-12-05
申请人： Maria E. Bennett , Joseph W. Boggs, II , John Chae
发明人： Maria E. Bennett , Joseph W. Boggs, II , John Chae
IPC分类号： A61N1/00 , A61B18/04 , A61B18/18 , A61N1/36 , A61N1/04 , A61N1/05
CPC分类号： A61N1/0504 , A61N1/025 , A61N1/0456 , A61N1/0502 , A61N1/0551 , A61N1/08 , A61N1/36071
摘要： Systems and methods are provided for treating chronic pain occurring secondarily to subacromial impingement syndrome in a human body. A system is provided to deliver percutaneous electrical stimulation through at least one electrode to neurological motor points of the posterior and middle deltoid muscles to mediate such pain. One-time, continued and/or periodic dosing of treatment methods according to the present invention may result in a change to central nervous system maladaptive neuroplasticity.
摘要翻译：提供的系统和方法用于治疗二次发生在人体内的肩峰下冲击综合征的慢性疼痛。提供一种系统，用于通过至少一个电极将经皮电刺激递送到后三和三分之一肌肉的神经运动点，以调解这种疼痛。根据本发明的治疗方法的一次性，持续和/或定期给药可能导致中枢神经系统适应不良的神经可塑性的变化。

6. 发明授权

US08788046B2 Systems and methods for the treatment of pain through neural fiber stimulation 有权
公开(公告)号：US08788046B2
公开(公告)日：2014-07-22
申请号：US13309024
申请日：2011-12-01
申请人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
发明人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
IPC分类号： A61N1/34 , A61N1/36
CPC分类号： A61N1/36071 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36057
摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

7. 发明授权

US08626302B2 Systems and methods to place one or more leads in muscle for providing electrical stimulation to treat pain 有权
标题翻译：将一个或多个引线放置在肌肉中以提供电刺激以治疗疼痛的系统和方法
公开(公告)号：US08626302B2
公开(公告)日：2014-01-07
申请号：US12462371
申请日：2009-08-03
申请人： Maria E. Bennett , Geoffrey B. Thrope , Joseph W. Boggs, II , Andreas Inmann , John Chae
发明人： Maria E. Bennett , Geoffrey B. Thrope , Joseph W. Boggs, II , Andreas Inmann , John Chae
IPC分类号： A61N1/04
CPC分类号： A61N1/05 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： Systems and methods are adapted to provide the relief of pain. The systems and methods make possible the percutaneous placement of one or more intramuscular leads, without the need for fluoroscopy, for providing electrical stimulation to activate a motor point innervating the muscle, to provide the therapeutic relief of pain. The one or more intramuscular leads may be placed in muscle(s) to resist migration. The target nerves and their motor points innervate the muscles in which the one or more leads are placed. The systems and methods can include a two-stage solution. The first stage may include temporary systems and methods, including the use of an external pulse generator. The second stage may include more permanent systems and methods, including the use of an implanted pulse generator.
摘要翻译：系统和方法适应于缓解疼痛。系统和方法使得一个或多个肌内引线的经皮放置成为可能，而不需要荧光透视，用于提供电刺激以激活支配肌肉的运动点，以提供疼痛的治疗缓解。一个或多个肌内引线可以放置在肌肉中以抵抗迁移。目标神经及其运动点支配放置一根或多根引线的肌肉。系统和方法可以包括两阶段解决方案。第一阶段可以包括临时系统和方法，包括使用外部脉冲发生器。第二阶段可以包括更永久的系统和方法，包括使用植入式脉冲发生器。

8. 发明授权

US08165685B1 System and method for therapeutic neuromuscular electrical stimulation 有权
标题翻译：治疗神经肌肉电刺激的系统和方法
公开(公告)号：US08165685B1
公开(公告)日：2012-04-24
申请号：US11536495
申请日：2006-09-28
申请人： Jayme S. Knutson , John Chae
发明人： Jayme S. Knutson , John Chae
IPC分类号： A61N1/00
CPC分类号： A61N1/36003 , A61N1/0452 , A61N1/0456 , A61N1/0484 , A61N1/36014
摘要： A system for neuromuscular electrical stimulation therapy includes one or more sensors for sensing the position or the muscle contractions of a body part, such as an arm, hand, finger, leg, etc.; a stimulator in communication with the sensor or sensors; and two or more electrodes that can be positioned to activate the paralyzed body part. Based on signals from the one or more sensors, the stimulator can regulate the stimulation provided through the electrodes, including the intensity and duration of the electrical stimulation signal. The sensors can be assembled in a wearable article, such as a glove, sock, or sleeve, to monitor the position or muscle contractions of the healthy body part. The electrodes also may be assembled in a wearable device that allows customized placement of those electrodes.
摘要翻译：用于神经肌肉电刺激治疗的系统包括用于感测身体部位（例如手臂，手，手指，腿等）的位置或肌肉收缩的一个或多个传感器; 与传感器或传感器通信的刺激器; 以及两个或更多个可以被定位以激活瘫痪的身体部分的电极。基于来自一个或多个传感器的信号，刺激器可以调节通过电极提供的刺激，包括电刺激信号的强度和持续时间。传感器可以组装在诸如手套，袜子或袖子的可穿戴物品中，以监测健康身体部位的位置或肌肉收缩。电极也可以组装在允许定制放置那些电极的可穿戴装置中。

9. 发明授权

US08788048B2 Systems and methods for the treatment of pain through neural fiber stimulation 有权
公开(公告)号：US08788048B2
公开(公告)日：2014-07-22
申请号：US13309152
申请日：2011-12-01
申请人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
发明人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
IPC分类号： A61N1/34 , A61N1/36
CPC分类号： A61N1/36071 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36057 , A61N1/36139
摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

10. 发明申请

US20120310302A1 SYSTEMS AND METHODS FOR THE TREATMENT OF PAIN THROUGH NEURAL FIBER STIMULATION 有权
公开(公告)号：US20120310302A1
公开(公告)日：2012-12-06
申请号：US13309152
申请日：2011-12-01
申请人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
发明人： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Grill , John Chae
IPC分类号： A61N1/36 , A61N1/04
CPC分类号： A61N1/36071 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36057 , A61N1/36139
摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

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