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    • 3. 发明授权
    • Intraocular lens and haptics made of a copolymer
    • 由共聚物制成的人工晶状体和触觉
    • US06267784B1
    • 2001-07-31
    • US09070771
    • 1998-05-01
    • Patrick H. BenzJose A. Ors
    • Patrick H. BenzJose A. Ors
    • A61F216
    • A61F2/16A61L27/16A61L2430/16C08L33/12G02B1/043Y10S623/901Y10S623/926A61L27/52C08L33/14
    • A one piece intraocular lens and an intraocular lens include an optic portion and a haptic portion formed from a copolymer that includes an incorporated hydrophilic monomer and an incorporated alkoxyalkyl methacrylate monomer. The optic and haptic portions of the one-piece intraocular lens and intraocular lens are formed from the same copolymer. The copolymer of intraocular lenses and preferred one-piece intraocular lenses includes about 40 to about 95 percent by weight of the hydrophilic monomer based on the total weight of the dry copolymer and about 5 to about 60 percent by weight of the alkoxyalkyl methacrylate based on the total weight of the dry copolymer. A blank for use in constructing an intraocular lens includes a hydrogel in a shape suitable for finishing into an intraocular lens. The hydrogel of the blank comprises a first portion suitable for finishing into a haptic portion and a second portion suitable for finishing into an optic portion. The first and second portions of the blank are formed of the same or a different copolymer of a hydrophilic monomer and an alkoxyalkyl methacrylate monomer, and the amount of the hydrophilic monomer present in the copolymer of the first portion of the blank ranges from about 60 to about 80 percent by weight based on the total weight of the dry copolymer in the first portion. Copolymers of the blank and one-piece intraocular lenses have an equilibrium water content of from about 10 to about 38 percent by weight based on the total weight of the hydrated copolymer.
    • 单片眼内透镜和人工晶状体包括视觉部分和由共聚物形成的触觉部分,所述共聚物包括引入的亲水性单体和引入的烷氧基烷基甲基丙烯酸酯单体。 单片眼内透镜和眼内透镜的视觉和触觉部分由相同的共聚物形成。 基于干共聚物的总重量,眼内透镜和优选的单件眼内透镜的共聚物包含约40至约95重量%的亲水性单体,约5-约60重量%的甲氧基烷基烷基酯基于 干共聚物的总重量。 用于构建眼内透镜的坯料包括适于整理成人工晶状体的形状的水凝胶。 坯料的水凝胶包括适于整理成触觉部分的第一部分和适于整理成光学部分的第二部分。 坯料的第一部分和第二部分由亲水单体和甲基丙烯酸烷氧基烷基酯单体的相同或不同的共聚物形成,并且存在于坯料的第一部分的共聚物中的亲水性单体的量为约60至 约80重量%,基于第一部分中的干共聚物的总重量。 基于水合共聚物的总重量,坯料和单件眼内透镜的共聚物的平衡水含量为约10至约38重量%。