专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08847154B2 Ion transfer tube for a mass spectrometer system 有权
标题翻译：用于质谱仪系统的离子转移管
公开(公告)号：US08847154B2
公开(公告)日：2014-09-30
申请号：US13333948
申请日：2011-12-21
申请人： Eloy R. Wouters , Alexander A. Makarov , R. Paul Atherton , Jean Jacques Dunyach
发明人： Eloy R. Wouters , Alexander A. Makarov , R. Paul Atherton , Jean Jacques Dunyach
IPC分类号： H01J49/26 , H01J49/42 , H01J49/04
CPC分类号： H01J49/0404 , B23H7/02 , B23H9/14
摘要： An ion transfer tube for a mass spectrometer comprises a core member and a first jacket tube member at least partially enclosing the core member and providing one or more channels therethrough. A method of forming an ion transfer tube, comprises: providing a first jacket tube member having a length and an internal bore, the internal bore passing along the length and defining an interior surface of circular cross section; removing at least one portion of the first jacket tube member adjacent to the interior surface so as to form at least one groove, channel, slot, recess or embayment of or in the interior surface; and providing a core member within the bore of the jacket tube member such that remnant portions of the interior surface of circular cross section mate against portions of an exterior surface of the core member.
摘要翻译：用于质谱仪的离子传递管包括芯构件和至少部分地包围芯构件并且提供穿过其中的一个或多个通道的第一护套管构件。一种形成离子转移管的方法，包括：提供具有长度和内孔的第一套管构件，所述内孔沿着所述长度通过并限定圆形横截面的内表面; 移除与所述内表面相邻的所述第一套管构件的至少一部分，以便形成所述内表面中或所述内表面中的至少一个凹槽，通道，槽，凹槽或沉积物; 并且在所述护套管构件的所述孔内提供芯构件，使得所述圆形横截面的内表面的残留部分与所述芯构件的外表面的部分配合。

2. 发明授权

US08058611B2 System for preventing backflow in an ion source 有权
标题翻译：用于防止离子源回流的系统
公开(公告)号：US08058611B2
公开(公告)日：2011-11-15
申请号：US12565598
申请日：2009-09-23
申请人： Eloy R. Wouters , Christopher Mullen , Maurizio A. Splendore , R. Paul Atherton
发明人： Eloy R. Wouters , Christopher Mullen , Maurizio A. Splendore , R. Paul Atherton
IPC分类号： H01J49/26
CPC分类号： H01J49/0445
摘要： A system for preventing backflow as part of an ion source arrangement is introduced. Such a system incorporates a novel continuous flow guide within a source, such as an API ion source. In the spray direction, the cross-sectional area that defines the first portion of the internal volume initially decreases in a convergent-like manner and thereafter increases in a divergent-like manner towards the exit opening of the source housing. Such a flow guide has been designed as an integral part of an ion source housing to provide for an optimal unidirectional flow past a sampling orifice of a mass spectrometer inlet. Accordingly, the novel design of the present invention prevents recirculation and thus minimizes carryover, chemical noise, and source turbulence and as an added benefit, enables a user to easily clean such a system during maintenance.
摘要翻译：引入了用于防止作为离子源装置的一部分的回流的系统。这样的系统在源内包含新颖的连续流动引导件，例如API离子源。在喷射方向上，限定内部容积的第一部分的横截面面积首先以收敛方式减小，然后以发散方式朝向源壳体的出口开口增加。这种流动引导件已被设计为离子源壳体的组成部分，以提供通过质谱仪入口的采样孔的最佳单向流动。因此，本发明的新颖设计防止再循环，从而使携带，化学噪声和源湍流最小化，并且作为附加的益处，使得用户能够在维护期间容易地清洁这样的系统。

3. 发明申请

US20110068263A1 System for Preventing Backflow in an Ion Source 有权
标题翻译：防止离子源回流的系统
公开(公告)号：US20110068263A1
公开(公告)日：2011-03-24
申请号：US12565598
申请日：2009-09-23
申请人： Eloy R. WOUTERS , Christopher MULLEN , Maurizio A. SPLENDORE , R. Paul ATHERTON
发明人： Eloy R. WOUTERS , Christopher MULLEN , Maurizio A. SPLENDORE , R. Paul ATHERTON
IPC分类号： H01J49/26
CPC分类号： H01J49/0445
摘要： A system for preventing backflow as part of an ion source arrangement is introduced. Such a system incorporates a novel continuous flow guide within a source, such as an API ion source. In the spray direction, the cross-sectional area that defines the first portion of the internal volume initially decreases in a convergent-like manner and thereafter increases in a divergent-like manner towards the exit opening of the source housing. Such a flow guide has been designed as an integral part of an ion source housing to provide for an optimal unidirectional flow past a sampling orifice of a mass spectrometer inlet. Accordingly, the novel design of the present invention prevents recirculation and thus minimizes carryover, chemical noise, and source turbulence and as an added benefit, enables a user to easily clean such a system during maintenance.
摘要翻译：引入了用于防止作为离子源装置的一部分的回流的系统。这样的系统在源内包含新颖的连续流动引导件，例如API离子源。在喷射方向上，限定内部容积的第一部分的横截面面积首先以收敛方式减小，然后以发散方式朝向源壳体的出口开口增加。这种流动引导件已被设计为离子源壳体的组成部分，以提供通过质谱仪入口的采样孔的最佳单向流动。因此，本发明的新颖设计防止再循环，从而使携带，化学噪声和源湍流最小化，并且作为附加的益处，使得用户能够在维护期间容易地清洁这样的系统。

4. 发明授权

US08759757B2 Interchangeable ion source for electrospray and atmospheric pressure chemical ionization 有权
标题翻译：用于电喷雾和大气压化学电离的可互换离子源
公开(公告)号：US08759757B2
公开(公告)日：2014-06-24
申请号：US13280069
申请日：2011-10-24
申请人： Mark Hardman , Jean-Jacques Dunyach , R. Paul Atherton , Michael W. Belford
发明人： Mark Hardman , Jean-Jacques Dunyach , R. Paul Atherton , Michael W. Belford
IPC分类号： H01J49/04 , H01J49/10 , H01J49/16 , H01J49/14
CPC分类号： H01J49/167 , H01J49/107 , H01J49/145 , H01J49/165
摘要： A ion source for a mass spectrometer comprises: a capillary having a nozzle for emitting a nebulized fluid sample; an electrode of the capillary; a high voltage power supply; a second electrode disposed within or configurable to be disposed within a path of the nebulized fluid sample; and at least one switch for selecting application of an electrical potential provided by the high voltage power supply to either or both of the capillary electrode or the second electrode, wherein the capillary and capillary electrode are configurable so as to ionize the nebulized fluid sample by electrospray ionization and the second electrode is configurable so as to ionize the nebulized sample by atmospheric pressure chemical ionization.
摘要翻译：用于质谱仪的离子源包括：具有用于发射雾化流体样品的喷嘴的毛细管; 毛细管的电极; 高压电源; 设置在所述喷雾流体样本的路径内或可配置为设置在所述雾化流体样本的路径内的第二电极; 以及至少一个开关，用于选择将所述高电压电源提供给所述毛细管电极或所述第二电极中的任一个或两者的电位施加，其中所述毛细管和毛细管电极可配置为通过电喷雾使雾化的流体样品电离电离和第二电极是可配置的，以便通过大气压化学电离使雾化的样品离子化。

5. 发明授权

US08461524B2 Ion guide with improved gas dynamics and combined noise reduction device 有权
标题翻译：离子导向器具有改进的气体动力学和组合降噪装置
公开(公告)号：US08461524B2
公开(公告)日：2013-06-11
申请号：US13073880
申请日：2011-03-28
申请人： Jean Jacques Dunyach , August A. Specht , R. Paul Atherton
发明人： Jean Jacques Dunyach , August A. Specht , R. Paul Atherton
IPC分类号： H01J49/44 , H01J49/26
CPC分类号： H01J49/063 , H01J49/044 , H01J49/24
摘要： A mass spectrometry system arrangement includes a curved ion guide, where the curve of the ion guide is positioned such that a portion of the ion optics are visible from at the ion guide entrance, e.g. line of sight or z-axis. There are four electrodes parallel with each other and the central curved axis. Each electrode is equally radially spaced from the curved central axis. For each cross section of the ion guide, the central curved axis being positioned at the origin, the curved electrodes being radially positioned at 45°, 135°, 225°, and 315°. Depending upon the system, a blocking device is positioned external to the ion guide but within the “line of sight” or positioned tangential to the rising section of the bent ion guide.
摘要翻译：质谱系统布置包括弯曲离子导向器，其中离子导向器的曲线被定位成使得离子光学器件的一部分可以在离子导向入口处可见，例如离子导向器。视线或z轴。有四个电极彼此平行和中心弯曲的轴线。每个电极与弯曲的中心轴线径向间隔开。对于离子导向件的每个横截面，中心弯曲轴线位于原点，弯曲电极径向定位在45°，135°，225°和315°处。取决于系统，阻挡装置位于离子导向器的外部，但位于“视线”内或定位成与弯曲离子导向件的上升部分相切。

6. 发明授权

US08237115B2 Method and apparatus for multiple electrospray emitters in mass spectrometry 有权
标题翻译：质谱法中多重电喷发射体的方法和装置
公开(公告)号：US08237115B2
公开(公告)日：2012-08-07
申请号：US12642617
申请日：2009-12-18
申请人： Viatcheslav V. Kovtoun , Eloy R. Wouters , R. Paul Atherton
发明人： Viatcheslav V. Kovtoun , Eloy R. Wouters , R. Paul Atherton
IPC分类号： H01J49/00
CPC分类号： H01J49/167 , H01J49/068
摘要： An electrospray ion source apparatus comprises: a plurality of emitter capillaries, each comprising an internal bore for transporting a portion of a liquid sample from a source, an electrode portion for providing a first applied electric potential and an emitter tip for emitting charged particles generated from the liquid sample portion; a counter electrode for providing a second applied electric potential different from the first applied electric potential; and at least one shield electrode disposed at least partially between the counter electrode and the emitter tip of at least one of the emitter capillaries for providing a third applied electric potential intermediate to the first and second applied electric potentials, wherein the at least one shield electrode is configured such that provision of the third applied electric potential to the at least one shield electrode provides a uniformity of emission of charged particles from the plurality of emitter tips.
摘要翻译：电喷雾离子源装置包括：多个发射器毛细管，每个发射器毛细管包括用于从源极输送液体样品的一部分的内孔，用于提供第一施加电位的电极部分和用于发射由液体样品部分; 用于提供不同于第一施加电位的第二施加电位的对电极; 以及至少一个屏蔽电极，至少部分地设置在所述发射极毛细管中的至少一个的所述对电极和所述发射极尖之间，用于向所述第一和第二施加电位提供中间的第三施加电位，其中所述至少一个屏蔽电极配置成使得向至少一个屏蔽电极提供第三施加电位提供了从多个发射极尖端发射带电粒子的均匀性。

7. 发明授权

US08546753B2 Method and apparatus for multiple electrospray emitters in mass spectrometry 有权
标题翻译：质谱法中多重电喷发射体的方法和装置
公开(公告)号：US08546753B2
公开(公告)日：2013-10-01
申请号：US13550369
申请日：2012-07-16
申请人： Viatcheslav V. Kovtoun , Eloy R. Wouters , R. Paul Atherton
发明人： Viatcheslav V. Kovtoun , Eloy R. Wouters , R. Paul Atherton
IPC分类号： H01J49/00
CPC分类号： H01J49/167 , H01J49/068
摘要： An electrospray ion source apparatus comprises: a plurality of emitter capillaries, each comprising an internal bore for transporting a portion of a liquid sample from a source, an electrode portion for providing a first applied electric potential and an emitter tip for emitting a cloud of charged particles generated from the liquid sample portion; a counter electrode for providing a second applied electric potential different from the first applied electric potential; and at least one shield electrode disposed at least partially between the counter electrode and the emitter tip of at least one of the emitter capillaries for providing a third applied electric potential intermediate to the first and second applied electric potentials, wherein the at least one shield electrode is configured such that provision of the third applied electric potential to the at least one shield electrode minimizes electric field interference effects between the plurality of emitter capillaries.
摘要翻译：电喷雾离子源设备包括：多个发射器毛细管，每个发射器毛细管包括用于从源极输送液体样品的一部分的内孔，用于提供第一施加电位的电极部分和用于发射带电的云的发射器尖端从液体样品部分产生的颗粒; 用于提供不同于第一施加电位的第二施加电位的对电极; 以及至少一个屏蔽电极，至少部分地设置在所述发射极毛细管中的至少一个的所述对电极和所述发射极尖之间，用于向所述第一和第二施加电位提供中间的第三施加电位，其中所述至少一个屏蔽电极被配置为使得向至少一个屏蔽电极提供第三施加电位使得多个发射器毛细管之间的电场干扰效应最小化。

8. 发明授权

US08309916B2 Ion transfer tube having single or multiple elongate bore segments and mass spectrometer system 有权
标题翻译：离子转移管具有单个或多个细长孔段和质谱仪系统
公开(公告)号：US08309916B2
公开(公告)日：2012-11-13
申请号：US12858726
申请日：2010-08-18
申请人： Eloy R. Wouters , Alexander A. Makarov , R. Paul Atherton , Jean Jacques Dunyach
发明人： Eloy R. Wouters , Alexander A. Makarov , R. Paul Atherton , Jean Jacques Dunyach
IPC分类号： H01J49/26
CPC分类号： H01J49/0404
摘要： An ion transfer tube for a mass spectrometer comprises a tube member having an inlet end and an outlet end; and at least one bore extending through the tube member from the inlet end to the outlet end, the at least one bore having a non-circular cross section. A method of forming an ion transfer tube comprises the steps of providing a tube member having a length and an internal bore, the internal bore having a wall of circular cross section; and etching or eroding portions of the tube member adjacent to the wall so as to form an enlarged bore having a non-circular cross section.
摘要翻译：用于质谱仪的离子转移管包括具有入口端和出口端的管构件; 以及至少一个孔，其从所述入口端延伸到所述管构件到所述出口端，所述至少一个孔具有非圆形横截面。形成离子转移管的方法包括以下步骤：提供具有长度和内孔的管构件，所述内孔具有圆形横截面的壁; 并且蚀刻或侵蚀与壁相邻的管构件的部分，以便形成具有非圆形横截面的扩大孔。

9. 发明授权

US08162090B2 Powered foldable scooter 失效
标题翻译：动力折叠滑板车
公开(公告)号：US08162090B2
公开(公告)日：2012-04-24
申请号：US12299991
申请日：2007-05-08
申请人： Paul Atherton , Andrew Graham , Kurt Walas
发明人： Paul Atherton , Andrew Graham , Kurt Walas
IPC分类号： B62D61/00
CPC分类号： B62K3/002 , B60L11/1805 , B62K2204/00 , Y02T10/7005
摘要： A scooter has a platform on which a rider can stand, a front wheel attached to a steering system including an upstanding handle bar and rear wheel which is driven. The scooter can be folded at a hinge line across the platform so to allow it to collapse. A case for the scooter includes a front part and a rear part covering the front and rear wheels with the parts brought together by the collapsing of the platform. This folding action also uses a pivot link to move the front and rear wheels pivoted within the respective case parts to a folded position. The steering includes a headstock with the steering bar connected to the front fork by a drive coupling which converts the rotation of the steering bar about the generally vertical axis to the rotation of the fork about an inclined axis.
摘要翻译：踏板车具有骑车人可以站立的平台，附接到转向系统的前轮，该转向系统包括直立的手柄和被驱动的后轮。踏板车可以在铰链线上折叠穿过平台，以使其能够折叠。用于踏板车的壳体包括前部和后部，该前部和后部覆盖前轮和后轮，并且通过平台的折叠将部件收起在一起。该折叠动作还使用枢轴连杆将在相应的壳体部分内枢转的前后轮移动到折叠位置。转向架包括一个主轴箱，转向杆通过一个驱动联轴器连接到前叉上，该驱动联轴器将转向杆围绕大体上垂直的轴线旋转，使其相对于倾斜轴线的转动转动。

10. 发明申请

US20110147577A1 Method and Apparatus for Multiple Electrospray Emitters in Mass Spectrometry 有权
标题翻译：质谱法中多重电喷发射体的方法与装置
公开(公告)号：US20110147577A1
公开(公告)日：2011-06-23
申请号：US12642617
申请日：2009-12-18
申请人： Viatcheslav V. KOVTOUN , Eloy R. Wouters , R. Paul Atherton
发明人： Viatcheslav V. KOVTOUN , Eloy R. Wouters , R. Paul Atherton
IPC分类号： H01J49/00 , B01D59/44
CPC分类号： H01J49/167 , H01J49/068
摘要： An electrospray ion source apparatus comprises: a plurality of emitter capillaries, each comprising an internal bore for transporting a portion of a liquid sample from a source, an electrode portion for providing a first applied electric potential and an emitter tip for emitting charged particles generated from the liquid sample portion; a counter electrode for providing a second applied electric potential different from the first applied electric potential; and at least one shield electrode disposed at least partially between the counter electrode and the emitter tip of at least one of the emitter capillaries for providing a third applied electric potential intermediate to the first and second applied electric potentials, wherein the at least one shield electrode is configured such that provision of the third applied electric potential to the at least one shield electrode provides a uniformity of emission of charged particles from the plurality of emitter tips.
摘要翻译：电喷雾离子源装置包括：多个发射器毛细管，每个发射器毛细管包括用于从源极输送液体样品的一部分的内孔，用于提供第一施加电位的电极部分和用于发射由液体样品部分; 用于提供不同于第一施加电位的第二施加电位的对电极; 以及至少一个屏蔽电极，至少部分地设置在所述发射极毛细管中的至少一个的所述对电极和所述发射极尖之间，用于向所述第一和第二施加电位提供中间的第三施加电位，其中所述至少一个屏蔽电极配置成使得向至少一个屏蔽电极提供第三施加电位提供了从多个发射极尖端发射带电粒子的均匀性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式