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    • 2. 发明授权
    • Leadless tissue stimulation systems and methods
    • 无铅组织刺激系统和方法
    • US07996087B2
    • 2011-08-09
    • US12554234
    • 2009-09-04
    • Mark W. CowanDebra S. EchtRichard E. RileyAxel F. Brisken
    • Mark W. CowanDebra S. EchtRichard E. RileyAxel F. Brisken
    • A61N1/372
    • A61N1/3621A61N1/368A61N1/37205A61N1/37217A61N1/3756A61N1/3787
    • Systems including an implantable receiver-stimulator and an implantable controller-transmitter are used for leadless electrical stimulation of body tissues. Cardiac pacing and arrhythmia control is accomplished with one or more implantable receiver-stimulators and an external or implantable controller-transmitter. Systems are implanted by testing external or implantable devices at different tissue sites, observing physiologic and device responses, and selecting sites with preferred performance for implanting the systems. In these systems, a controller-transmitter is activated at a remote tissue location to transmit/deliver acoustic energy through the body to a receiver-stimulator at a target tissue location. The receiver-stimulator converts the acoustic energy to electrical energy for electrical stimulation of the body tissue. The tissue locations(s) can be optimized by moving either or both of the controller-transmitter and the receiver-stimulator to determine the best patient and device responses.
    • 包括可植入接收器刺激器和可植入控制器 - 发射器的系统用于身体组织的无引线电刺激。 心脏起搏和心律失常控制由一个或多个可植入接收器刺激器和外部或可植入控制器发射器来实现。 通过在不同组织部位测试外部或可植入装置,观察生理和装置反应以及选择具有植入系统的优选性能的部位植入系统。 在这些系统中,控制器 - 发射器在远程组织位置处被激活,以将声能通过身体发射/传递到目标组织位置处的接收器 - 刺激器。 接收器 - 刺激器将声能转换为电能以对身体组织进行电刺激。 可以通过移动控制器 - 发射器和接收器 - 刺激器中的任一者或两者来确定最佳患者和设备响应来优化组织位置。
    • 3. 发明申请
    • SYSTEMS AND METHODS FOR IMPLANTABLE LEADLESS GASTROINTESTINAL TISSUE STIMULATION
    • 无侵袭性胃肠道组织刺激的系统和方法
    • US20110112600A1
    • 2011-05-12
    • US13008521
    • 2011-01-18
    • Mark W. CowanRichard E. RileyAxel F. BriskenDebra S. Echt
    • Mark W. CowanRichard E. RileyAxel F. BriskenDebra S. Echt
    • A61N1/36
    • A61N1/05A61N1/36007A61N1/37217
    • Systems and methods are disclosed to stimulate gastrointestinal tissue to treat medical conditions such as eating disorders, gastroparesis, and gastric reflux. The invention uses electrical stimulation of the nerve, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined gastrointestinal tissue site. The vibrational energy is generated by a controller-transmitter, which could be implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located in the various regions on or around the gastrointestinal tissue that needs to be stimulated. The implantable receiver-stimulator stimulates different gastrointestinal tissue to provide the desired therapeutic benefit.
    • 公开了系统和方法以刺激胃肠组织来治疗诸如进食障碍,胃轻瘫,胃反流等医学病症。 本发明使用对神经的电刺激,其中来自源的振动能量被植入装置接收并转换成电能,并且所转换的电能被植入电极用于刺激预定的胃肠道组织部位。 振动能量由控制器 - 发射器产生,其可被植入或位于外部。 接收器刺激器接收振动能,其可以位于需要刺激的胃肠道组织上或周围的各个区域中。 可植入接收器刺激器刺激不同的胃肠道组织以提供所需的治疗益处。
    • 9. 发明授权
    • Thick film on metal encoder element
    • 金属编码器元件上的厚膜
    • US06248964B1
    • 2001-06-19
    • US09287771
    • 1999-04-07
    • Craig R. BaileyRichard E. RileyGeary GreenStephen J. Waszak
    • Craig R. BaileyRichard E. RileyGeary GreenStephen J. Waszak
    • H01H100
    • H05K3/244H01H1/403H01H19/585H05K3/28Y10T29/49105
    • A switching element, specifically an encoder element, is fabricated by forming a conductive track on an insulative substrate, and then screen printing an insulative layer on the track in a predetermined pattern that forms a contact array that comprises a plurality of conductive contacts separated by nonconductive areas. The substrate may be a polymeric resin, and the track comprises (a) a copper base layer formed on a surface of the substrate in the configuration of the track, (b) a first metal-plated layer, preferably of nickel, on the base layer, and (c) a second metal-plated layer, preferably of gold, on the first metal-plated layer. The insulative layer is formed of a thick film dielectric material comprising a difunctional monomer (e.g., diallyl isophthalate), a glycol ether ester (e.g., ethylene glycol monobutyl ether acetate), an inorganic filler (e.g., BaSO4), and an acetate surface modifier (e.g., an ethyl acrylate/ethylhexylacrylate copolymer). The screen-printed dielectric material on the conductive track results in an array of contacts separated by nonconductive areas that extend no more than about 30 microns above the surface of the contacts. An encoder element so fabricated includes first and second concentric annular contact arrays formed that concentrically surround a central collector contact.
    • 开关元件,特别是编码器元件,通过在绝缘基板上形成导电轨迹,然后以规定的图案丝网印刷绝缘层,所述绝缘层形成接触阵列,所述接触阵列包括由非导电性隔开的多个导电触点 地区 衬底可以是聚合物树脂,并且轨道包括(a)在轨道的构造中形成在基底的表面上的铜基底层,(b)基底上的第一金属镀层,优选镍, 层,以及(c)在第一金属镀层上的第二金属镀层,优选为金。 绝缘层由包括双官能单体(例如间苯二甲酸二烯丙酯),二醇醚酯(例如乙二醇单丁醚乙酸酯),无机填料(例如BaSO 4))和乙酸酯表面改性剂 (例如,丙烯酸乙酯/丙烯酸乙基己酯共聚物)。 在导电轨道上的丝网印刷电介质材料导致由非导电区域分开的触点阵列,其在触点表面上方延伸不超过约30微米。 如此制造的编码器元件包括形成为同心地围绕中心收集器触点的第一和第二同心环形接触阵列。