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1. 发明授权

US07434312B2 Method for manufacturing an implantable drug delivery device with peristaltic pump having a retractable roller 失效
标题翻译：用于具有可伸缩辊的蠕动泵的可植入药物输送装置的制造方法
公开(公告)号：US07434312B2
公开(公告)日：2008-10-14
申请号：US10826088
申请日：2004-04-16
申请人： Steven R. Christenson , Reginald D. Robinson , Kenneth T. Heruth , James M. Haase , Mandred K. Luedi
发明人： Steven R. Christenson , Reginald D. Robinson , Kenneth T. Heruth , James M. Haase , Mandred K. Luedi
IPC分类号： B23P15/00 , A61M1/00
CPC分类号： F04B43/1253 , A61M5/14232 , A61M5/14276 , A61M2205/0266 , F04B43/1276 , Y10T29/4924
摘要： An implantable drug infusion device includes a pump tube for holding a liquid to be pumped. A race is configured to support the pump tube. A roller assembly is configured to compress the tube against the race at one or more points along the path, and the roller assembly includes at least one roller and a hub. A drive assembly drives the roller assembly relative to the tube along the path so as to move the liquid through the tube. A retracting roller is operably connected to the hub and/or one or more adjacent rollers to permit retraction of the roller during installation of the pump tube between the roller and the race.
摘要翻译：可植入药物输注装置包括用于保持要泵送的液体的泵管。一个比赛被配置为支持泵管。辊组件构造成在沿着路径的一个或多个点处压缩套管抵抗座圈，并且辊组件包括至少一个辊和轮毂。驱动组件沿着路径相对于管驱动辊组件，以便使液体移动通过管。回缩辊可操作地连接到轮毂和/或一个或多个相邻的辊子上，以允许在将泵管安装在辊子和座圈之间时缩回辊子。

2. 发明授权

US07264611B2 Implantable infusion device with motor connection and seal system 有权
标题翻译：具有电机连接和密封系统的植入式输液装置
公开(公告)号：US07264611B2
公开(公告)日：2007-09-04
申请号：US10159561
申请日：2002-05-31
申请人： Steven R. Christenson , Mark S. Lent , Christian Peclat
发明人： Steven R. Christenson , Mark S. Lent , Christian Peclat
IPC分类号： A61M1/00 , A61K9/22
CPC分类号： A61M5/14276 , A61M5/1413
摘要： A medical device known as an implantable infusion device is configured for implanting in humans to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spasticity, cancer, and many other conditions. The infusion device incorporates a motor coil connector and mechanical sealing system between the clean motor compartment and the potentially corrosive pump compartment that provides a reliable electrical connection between the motor coil and the motor drive electronics. The motor coil connector provides for bonding of a very small diameter coil wire to one end of the connector and a highly corrosion resistant connection at the other end of the connector. Additionally, the motor coil connector and mechanical sealing system provides a seal against harmful corrosion materials that could emanate from the pump compartment and reach the motor compartment and cause malfunction of the motor. The infusion device has a housing, a power source, a therapeutic substance reservoir, a therapeutic substance pump, and electronics.
摘要翻译：被称为植入式输注装置的医疗装置被配置用于在人体中植入以输送治疗物质，例如药物组合物，遗传物质和生物制剂，以治疗各种医学病症如疼痛，痉挛状态，癌症等许多病症。输液装置包括电机线圈连接器和机械密封系统，位于清洁的电动机室和潜在的腐蚀性泵室之间，其在电动机线圈和电动机驱动电子装置之间提供可靠的电连接。马达线圈连接器用于将非常小直径的线圈线接合到连接器的一端，并且在连接器的另一端处具有高度耐腐蚀的连接。另外，电动机线圈连接器和机械密封系统提供了可以从泵室发出的有害腐蚀材料的密封，并到达电动机室并引起电动机故障。输液装置具有壳体，动力源，治疗物质储存器，治疗物质泵和电子装置。

3. 发明授权

US06626867B1 Implantable drug infusion device with peristaltic pump using tube guides 有权
标题翻译：具有蠕动泵的植入式药物输注装置，使用导管
公开(公告)号：US06626867B1
公开(公告)日：2003-09-30
申请号：US09561154
申请日：2000-04-28
申请人： Steven R. Christenson , Reginald D. Robinson , James M. Haase , Manfred K. Lüedi
发明人： Steven R. Christenson , Reginald D. Robinson , James M. Haase , Manfred K. Lüedi
IPC分类号： A61M100
CPC分类号： A61M5/14276 , A61M5/14232 , A61M2205/0266 , F04B43/1253
摘要： An implantable drug infusion device includes a pump tube for holding a liquid to be pumped. A race is configured to support the tube. A roller assembly is configured to compress the tube against the race at one or more points along the path, and the roller assembly includes at least one roller. A tube guide is operably connected to the roller assembly to align the pump tube with respect to a corresponding roller.
摘要翻译：可植入药物输注装置包括用于保持要泵送的液体的泵管。比赛被配置为支撑管。辊组件构造成在沿着路径的一个或多个点上压缩管抵抗座圈，并且辊组件包括至少一个辊。管引导件可操作地连接到辊组件以使泵管相对于相应的辊对准。

4. 发明授权

US09737660B2 Drug infusion device with controllable valve 有权
公开(公告)号：US09737660B2
公开(公告)日：2017-08-22
申请号：US13217981
申请日：2011-08-25
申请人： Reginald D. Robinson , Mary E. Robischon , Bernard Q. Li , Irfan Z. Ali , Steven R. Christenson , Keith A. Miesel
发明人： Reginald D. Robinson , Mary E. Robischon , Bernard Q. Li , Irfan Z. Ali , Steven R. Christenson , Keith A. Miesel
IPC分类号： A61M5/168 , A61M39/22 , A61M5/142
CPC分类号： A61M5/16827 , A61M5/14276 , A61M5/1684 , A61M39/223 , A61M2205/3523 , A61M2205/3569 , A61M2210/1003
摘要： A therapeutic fluid delivery device that includes at least one controllable valve is generally described. In one example, an implantable therapeutic fluid delivery system includes a first fluid pathway configured to convey a first therapeutic fluid and a second fluid pathway configured to convey a second therapeutic fluid, the second fluid pathway being separate from the first fluid pathway. The therapeutic fluid delivery system includes a valve connected to the first fluid pathway and the second fluid pathway, and a processor configured to control actuation of the valve to open and close the first fluid pathway and to open and close the second fluid pathway.

5. 发明授权

US09259530B2 Implantable infusion device 有权
标题翻译：植入式输液装置
公开(公告)号：US09259530B2
公开(公告)日：2016-02-16
申请号：US12625694
申请日：2009-11-25
申请人： Steven R. Christenson
发明人： Steven R. Christenson
IPC分类号： A61M5/142 , A61M5/14 , A61M5/168 , A61M39/24 , A61M39/02
CPC分类号： A61M5/14276 , A61M5/141 , A61M5/16813 , A61M2039/0244 , A61M2039/242
摘要： An implantable infusion device includes a positive pressure reservoir, a pump, a flow restrictor, and an outlet. The device includes a first fluid flow path from the reservoir to the outlet, where the pump is downstream of the reservoir, and the outlet is downstream of the pump. The device further includes a second fluid flow path from the reservoir to the outlet, where the flow restrictor is downstream of the reservoir, and the outlet is downstream of the restrictor. The device may also include one or more controllable, MRI-safe valves to select whether fluid is delivered via the first or second flow path.
摘要翻译：可植入式输液装置包括正压储存器，泵，限流器和出口。该装置包括从储存器到出口的第一流体流动路径，其中泵在储存器的下游，并且出口在泵的下游。该装置还包括从储存器到出口的第二流体流动路径，其中流量限制器位于储存器的下游，并且出口在限流器的下游。该装置还可以包括一个或多个可控的MRI安全阀，以选择是否经由第一或第二流动路径输送流体。

6. 发明授权

US08608729B2 Implantable infusion device having filter 有权
标题翻译：具有过滤器的植入式输液装置
公开(公告)号：US08608729B2
公开(公告)日：2013-12-17
申请号：US12105441
申请日：2008-04-18
申请人： Steven R. Christenson
发明人： Steven R. Christenson
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61M5/14212 , A61M5/165 , A61M5/38 , A61M2205/7518
摘要： An implantable infusion device for delivering a fluid medication to a patient. The infusion device has an internal bacterial filter positioned between the reservoir and the pump, configured to provide a pathway for fluid to be pulled from the reservoir to the pump, regardless of the orientation of the infusion device. The configuration of the filter provides a fluid pathway from the reservoir to the pump, even in the presence of a gas bubble.
摘要翻译：一种用于将流体药物递送到患者的可植入输注装置。输液装置具有位于储存器和泵之间的内部细菌过滤器，其被配置为提供用于将流体从储存器拉到泵的通道，而与输注装置的取向无关。过滤器的结构提供了从储存器到泵的流体通道，甚至在存在气泡的情况下也是如此。

7. 发明授权

US06485464B1 Reduced height implantable drug infusion device 有权
标题翻译：减少高度可植入药物输注装置
公开(公告)号：US06485464B1
公开(公告)日：2002-11-26
申请号：US09560173
申请日：2000-04-28
申请人： Steven R. Christenson , Reginald D. Robinson , Kenneth T. Heruth , James Randall , Manfred K. L{overscore (u)}edi , Christian Pèclat
发明人： Steven R. Christenson , Reginald D. Robinson , Kenneth T. Heruth , James Randall , Manfred K. L{overscore (u)}edi , Christian Pèclat
IPC分类号： F04B4312
CPC分类号： A61M5/14276 , A61M5/14232
摘要： An implantable drug infusion device includes a pumphead assembly and a motor assembly operably connected to the pumphead assembly. The motor assembly is adjacent to and laterally offset from the pumphead assembly, advantageously reducing the overall height of the implantable drug infusion device.
摘要翻译：可植入药物输注装置包括可操作地连接到泵头组件的泵头组件和马达组件。马达组件与泵头组件相邻并且横向偏移，有利地减小了可植入药物输注装置的整体高度。

8. 发明申请

US20110125137A1 IMPLANTABLE INFUSION DEVICE 有权
标题翻译：可植入式输液装置
公开(公告)号：US20110125137A1
公开(公告)日：2011-05-26
申请号：US12625694
申请日：2009-11-25
申请人： Steven R. Christenson
发明人： Steven R. Christenson
IPC分类号： A61M31/00
CPC分类号： A61M5/14276 , A61M5/141 , A61M5/16813 , A61M2039/0244 , A61M2039/242
摘要： An implantable infusion device includes a positive pressure reservoir, a pump, a flow restrictor, and an outlet. The device includes a first fluid flow path from the reservoir to the outlet, where the pump is downstream of the reservoir, and the outlet is downstream of the pump. The device further includes a second fluid flow path from the reservoir to the outlet, where the flow restrictor is downstream of the reservoir, and the outlet is downstream of the restrictor. The device may also include one or more controllable, MRI-safe valves to select whether fluid is delivered via the first or second flow path.
摘要翻译：可植入式输液装置包括正压储存器，泵，限流器和出口。该装置包括从储存器到出口的第一流体流动路径，其中泵在储存器的下游，并且出口在泵的下游。该装置还包括从储存器到出口的第二流体流动路径，其中流量限制器位于储存器的下游，并且出口在限流器的下游。该装置还可以包括一个或多个可控的MRI安全阀，以选择是否经由第一或第二流动路径输送流体。

9. 发明授权

US06733476B2 Implantable drug delivery device with peristaltic pump having a bobbin roller assembly 失效
标题翻译：具有蠕动泵的可植入药物输送装置具有筒管辊组件
公开(公告)号：US06733476B2
公开(公告)日：2004-05-11
申请号：US09835208
申请日：2001-04-13
申请人： Steven R. Christenson , James Randall , Micheal Thomas Hegland , James M. Haase , Mark S. Lent , William H. Monsen
发明人： Steven R. Christenson , James Randall , Micheal Thomas Hegland , James M. Haase , Mark S. Lent , William H. Monsen
IPC分类号： A61M100
CPC分类号： A61M5/14232 , A61M5/14276 , A61M2205/0266 , F04B43/1253 , F04B43/1276
摘要： An implantable drug infusion device includes a pump tube for holding a liquid to be pumped. A race is configured to support the pump tube. A roller assembly is configured to compress the tube against the race at one or more points along the path, and the roller assembly includes at least one roller. A drive assembly drives the roller assembly relative to the tube along the path so as to move the liquid through the tube. At least two biasing members are operably connected to the roller to bias the roller against the tube, the two biasing members forming an angle.
摘要翻译：可植入药物输注装置包括用于保持要泵送的液体的泵管。一个比赛被配置为支持泵管。辊组件构造成在沿着路径的一个或多个点上压缩管抵抗座圈，并且辊组件包括至少一个辊。驱动组件沿着路径相对于管驱动辊组件，以便使液体移动通过管。至少两个偏置构件可操作地连接到辊子上，以将辊抵靠管子偏压，两个偏置构件形成一个角度。

10. 发明授权

US06645176B1 Spring loaded implantable drug infusion device 失效
标题翻译：弹簧加载植入式药物输液装置
公开(公告)号：US06645176B1
公开(公告)日：2003-11-11
申请号：US09561583
申请日：2000-04-28
申请人： Steven R. Christenson , Reginald D. Robinson , Kenneth T. Heruth , James M. Haase , James Randall , Christian Pèclat , Manfred K. Lüedi
发明人： Steven R. Christenson , Reginald D. Robinson , Kenneth T. Heruth , James M. Haase , James Randall , Christian Pèclat , Manfred K. Lüedi
IPC分类号： A61M100
CPC分类号： A61M5/14276 , A61M5/14232
摘要： An implantable drug infusion device includes a pump tube for holding a liquid to be pumped. A race is configured to support the tube. A roller assembly is configured to compress the tube against the race at one or more points along the path, and the roller assembly includes at least one roller. A drive assembly drives the roller assembly relative to the tube along the path so as to move the liquid through the tube. A biasing member is operably connected to the at least one roller to bias the at least one roller against the tube.
摘要翻译：可植入药物输注装置包括用于保持要泵送的液体的泵管。比赛被配置为支撑管。辊组件构造成在沿着路径的一个或多个点上压缩管抵抗座圈，并且辊组件包括至少一个辊。驱动组件沿着路径相对于管驱动辊组件，以便使液体移动通过管。偏置构件可操作地连接到所述至少一个辊以将所述至少一个辊偏压抵靠所述管。

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