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    • 1. 发明授权
    • Automated fiber tracking of human brain white matter using diffusion tensor imaging
    • 使用扩散张量成像自动光纤跟踪人脑白质
    • US08593142B2
    • 2013-11-26
    • US12743169
    • 2009-01-05
    • Susumu MoriJiangyang ZhangKegang Hua
    • Susumu MoriJiangyang ZhangKegang Hua
    • G01V3/00
    • G01R33/56341A61B5/055G06T7/11G06T7/344G06T2207/10092G06T2207/30016
    • A magnetic resonance imaging (MRI) system, comprising: a MRI scanner; a signal processing system in communication with the magnetic resonance imaging scanner to receive magnetic resonance (MR) signals for forming magnetic resonance images of a subject under observations; a data storage unit in communication with the signal processing system, wherein the data storage unit contains database data corresponding to a soft tissue region of the subject under observation. The database data includes information identifying at least one soft tissue substructure encompassed by the soft tissue region of the subject under observation. The signal processing system is adapted to process MR signals received from the MRI scanner to automatically identify at least one soft tissue substructure encompassed by the soft tissue region of the subject under observation.
    • 一种磁共振成像(MRI)系统,包括:MRI扫描仪; 信号处理系统,其与所述磁共振成像扫描仪通信以接收用于形成观察对象的磁共振图像的磁共振(MR)信号; 与所述信号处理系统通信的数据存储单元,其中所述数据存储单元包含对应于所观察对象的软组织区域的数据库数据。 数据库数据包括识别被观察对象的软组织区域包围的至少一个软组织亚结构的信息。 所述信号处理系统适于处理从所述MRI扫描器接收的MR信号,以自动识别所观察的受试者的软组织区域所包围的至少一个软组织亚结构。
    • 2. 发明授权
    • MRI methods using diffusion tensor imaging techniques and MRI systems embodying same
    • 使用扩散张量成像技术和体现其的MRI系统的MRI方法
    • US08577112B2
    • 2013-11-05
    • US12489682
    • 2009-06-23
    • Susumu MoriHangyi JiangMing-Chung ChouYue Li
    • Susumu MoriHangyi JiangMing-Chung ChouYue Li
    • G06K9/00
    • G01R33/56341A61B5/055
    • Featured is a method for automatically evaluating acquired MRI data, determining the quality of the acquired images and removing the image data when it is determined that an image is corrupted so the imaged data for the corrupted image is removed from the subsequent tensor fitting. In further embodiments, such determining includes judging the quality of the image data to determine if the image data satisfies a quality threshold criteria and if determined not to be satisfied adjudging the image to be corrupted. Such methods include performing said evaluating, determining and removing in real time and in the case where an image is determined to be corrupted, such methods further includes re-acquiring additional image data corresponding to each of the one or more images removed as being corrupted. Also featured are MRI systems embodying such methods.
    • 特色是一种自动评估获取的MRI数据,确定所获取的图像的质量并确定图像已损坏时删除图像数据的方法,以便从后续的张量拟合中删除损坏的图像的成像数据。 在另外的实施例中,这种确定包括判断图像数据的质量,以确定图像数据是否满足质量阈值标准,并且如果确定不满足判断被破坏的图像。 这样的方法包括实时地执行所述评估,确定和移除,并且在确定图像被破坏的情况下,这种方法还包括重新获取对应于被删除的一个或多个图像中的每一个被损坏的附加图像数据。 还有体现这种方法的MRI系统。
    • 4. 发明授权
    • Method of fiber reconstruction employing data acquired by magnetic resonance imaging
    • 采用磁共振成像获取的数据进行纤维重建的方法
    • US06526305B1
    • 2003-02-25
    • US09444346
    • 1999-11-19
    • Susumu Mori
    • Susumu Mori
    • A61B5055
    • G01R33/56341Y10S128/92
    • A method of creating an image of brain fibers includes exposing the brain fibers to a magnetic resonance imaging process. The data acquisition from the magnetic resonance imaging includes the acquisition of diffusion-weighted, images that are later employed to calculate an apparent diffusion constant at each pixel along more than six axes. The data is introduced into a microprocessor which calculates six variable in a diffusion tensor and obtains a plurality of eigen values and eigen vectors. This may be accomplished by employing a diffusion sensor which is diagonalized to obtain three eigen values and three eigen vectors with the six values being subjected to further microprocessing to generate imaging information representing the properties of the fibers. The process in a preferred embodiment includes the initiation of fiber tracking by selecting a pixel for initiation of the same, connecting of pixels and effecting a judgement regarding termination of the pixel tracking in each direction based upon the randomness of the fiber orientation of the adjacent pixels.
    • 创建脑纤维图像的方法包括将脑纤维暴露于磁共振成像过程。 来自磁共振成像的数据采集包括获取扩散加权的图像,其随后用于计算沿着六个以上轴的每个像素处的表观扩散常数。 数据被引入微处理器中,该微处理器在扩散张量中计算六个变量并获得多个本征值和特征向量。 这可以通过使用扩散传感器来实现,扩散传感器被对角化以获得三个本征值和三个特征向量,其中六个值经受进一步的微处理以产生表示纤维的性质的成像信息。 优选实施例中的过程包括通过选择用于启动相同像素的像素并且基于相邻像素的光纤取向的随机性来实现关于每个方向上的像素跟踪的终止的判断来启动光纤跟踪 。
    • 6. 发明授权
    • Exposure apparatus and method
    • 曝光装置和方法
    • US5657130A
    • 1997-08-12
    • US408714
    • 1995-03-22
    • Hiroshi ShirasuKazuaki SaikiSeiji MiyazakiSusumu Mori
    • Hiroshi ShirasuKazuaki SaikiSeiji MiyazakiSusumu Mori
    • G03F7/20G03F7/207G03F9/00H01L21/027G01B11/00
    • G03F7/70216G03F7/70275G03F7/70358G03F7/70791G03F9/70
    • In an exposure apparatus and method, a mask and a substrate are scanned in synchronism with each other so that the pattern of the mask may be transferred onto the substrate through a projection optical system. First beams of light are irradiated to least two locations on the mask spaced apart in a direction intersecting the scanning direction of the mask. The reflected light thereof is received, and the positions of the points on the mask to which the beam of light has been irradiated are detected in the direction of the optical axis of the projection optical system. In addition, second beams of light are irradiated to at least two locations on the substrate spaced apart in the scanning direction, and the reflected light thereof is received. The positions of the points on the substrate to which the second beam of light has been irradiated are also detected in the direction of the optical axis of the projection optical system are detected. The posture of at least one of the mask and the substrate is adjusted on the basis of the positions detected with the first and second beams.
    • 在曝光装置和方法中,掩模和基板彼此同步地扫描,使得掩模的图案可以通过投影光学系统被转印到基板上。 第一光束照射在与掩模的扫描方向相交的方向间隔开的掩模上的至少两个位置。 在投影光学系统的光轴的方向上检测其反射光,并且在光束照射的掩模上的点的位置被检测。 此外,第二光束照射到沿扫描方向间隔开的基板上的至少两个位置,并且其反射光被接收。 检测到在投影光学系统的光轴的方向上检测到已经照射第二光束的基板上的点的位置。 基于由第一和第二光束检测到的位置来调整掩模和基板中的至少一个的姿势。
    • 7. 发明申请
    • AUTOMATED IMAGE ANALYSIS FOR MAGNETIC RESONANCE IMAGING
    • 自动图像分析用于磁共振成像
    • US20150015253A1
    • 2015-01-15
    • US14248998
    • 2014-04-09
    • Susumu MoriMichael I. MillerJiangyang ZhangKenichi Oishi
    • Susumu MoriMichael I. MillerJiangyang ZhangKenichi Oishi
    • G01R33/56
    • G01R33/56G01R33/5608G01R33/56341G06T7/0012G06T7/11G06T7/30G06T2207/10088G06T2207/30016
    • A magnetic resonance imaging (MRI) system, comprising: a magnetic resonance imaging scanner configured to generate a plurality of signals for forming at least one magnetic resonance image of a soft tissue region from a subject under observation, wherein the at least one magnetic resonance image provides at least one integrating feature to facilitate automatic segmentation; a signal processing system in communication with the magnetic resonance imaging scanner to receive the plurality of signals; and a data storage unit in communication with the signal processing system, wherein the data storage unit contains at least one template corresponding to the soft tissue region, wherein the signal processing system is adapted to process the plurality of signals received from the magnetic resonance imaging scanner to automatically perform segmentation for the soft tissue region of the subject under observation by utilizing the at least one template and the at least one integrating feature.
    • 一种磁共振成像(MRI)系统,包括:磁共振成像扫描器,被配置为产生用于从观察对象形成软组织区域的至少一个磁共振图像的多个信号,其中所述至少一个磁共振图像 提供至少一个积分特征以促进自动分割; 信号处理系统,与所述磁共振成像扫描器通信以接收所述多个信号; 以及与所述信号处理系统通信的数据存储单元,其中所述数据存储单元包含与所述软组织区域对应的至少一个模板,其中所述信号处理系统适于处理从所述磁共振成像扫描器接收的所述多个信号 通过利用所述至少一个模板和所述至少一个积分特征来自动执行观察对象的软组织区域的分割。
    • 8. 发明授权
    • Atlas-based analysis for image-based anatomic and functional data of organism
    • 基于图像的生物体解剖学和功能数据分析
    • US08838201B2
    • 2014-09-16
    • US13703859
    • 2011-06-22
    • Susumu MoriAndreia V. FariaMichael I. MillerKenichi Oishi
    • Susumu MoriAndreia V. FariaMichael I. MillerKenichi Oishi
    • A61B5/05G06T7/00A61B6/00A61B5/055G06K9/20G01R33/56A61B6/03
    • G06K9/2054A61B5/055A61B6/03A61B6/5217G01R33/5608G06T7/11G06T7/149G06T2207/10072G06T2207/20128G06T2207/30016
    • A non-invasive imaging system, including an imaging scanner suitable to generate an imaging signal from a tissue region of a subject under observation, the tissue region having at least one anatomical substructure and more than one constituent tissue type; a signal processing system in communication with the imaging scanner to receive the imaging signal from the imaging scanner; and a data storage unit in communication with the signal processing system, wherein the data storage unit is configured to store a parcellation atlas comprising spatial information of the at least one substructure in the tissue region, wherein the signal processing system is adapted to: reconstruct an image of the tissue region based on the imaging signal; parcellate, based on the parcellation atlas, the at least one anatomical substructure in the image; segment the more than one constituent tissue types in the image; and automatically identify, in the image, a portion of the at least one anatomical substructure that correspond to one of the more than one constituent tissue type.
    • 一种非侵入性成像系统,包括适于从观察对象的组织区域产生成像信号的成像扫描器,所述组织区域具有至少一个解剖学亚结构和多于一种构成组织类型; 与成像扫描仪通信的信号处理系统,以从成像扫描仪接收成像信号; 以及与所述信号处理系统通信的数据存储单元,其中所述数据存储单元被配置为存储包括所述组织区域中的所述至少一个子结构的空间信息的分割图集,其中所述信号处理系统适于:重构 基于成像信号的组织区域的图像; 基于分割图谱分析图像中的至少一个解剖学亚结构; 在图像中分割多个组成组织类型; 并且在所述图像中自动识别所述至少一个解剖学亚结构的对应于多于一种构成组织类型之一的部分。
    • 9. 发明申请
    • SYSTEM FOR A THREE-DIMENSIONAL INTERFACE AND DATABASE
    • 三维接口和数据库系统
    • US20140181754A1
    • 2014-06-26
    • US14129552
    • 2012-06-28
    • Susumu MoriMichael I. Miller
    • Susumu MoriMichael I. Miller
    • G06F3/0484G06F3/0481
    • G06F3/04842G06F3/04815G06F16/444G06F16/48G06T19/00G06T2210/41G16H50/50
    • An embodiment in accordance with the present invention provides a system and method for a three-dimensional interface for interacting with a database. The three-dimensional interface can include an interactive three-dimensional atlas depicting an element of anatomy, machine, device, or other object. Given the three-dimensional nature of the atlas, a user can zoom in on particular areas to view them with more specificity. Different structural points of the anatomy are labeled with names or coordinates, such that the user can select one of the structural points and search a database for information related to that specific structural point. The user can also use specific keywords to search with respect to the specific structural point selected. The three-dimensional interface and atlas are displayed to the user on a computing device that can either house the database within its memory or alternately communicate with the database over a network.
    • 根据本发明的实施例提供了一种用于与数据库进行交互的三维界面的系统和方法。 三维界面可以包括描绘解剖结构,机器,装置或其他对象的元件的交互式三维图集。 鉴于地图集的三维性质,用户可以放大特定区域以更具体地查看它们。 解剖结构的不同结构点用名称或坐标标记,使得用户可以选择结构点之一并搜索数据库以获得与该特定结构点相关的信息。 用户还可以使用特定关键词来搜索所选择的特定结构点。 三维界面和图集在计算设备上显示给用户,该计算设备可以将数据库存储在其存储器内,或者通过网络交替地与数据库通信。
    • 10. 发明申请
    • IMAGE SEARCH ENGINE
    • 图像搜索引擎
    • US20130223716A1
    • 2013-08-29
    • US13824853
    • 2011-10-25
    • Susumu MoriMichael I. MillerKenichi OishiAndreia V. Faria
    • Susumu MoriMichael I. MillerKenichi OishiAndreia V. Faria
    • G06T7/00
    • G06T7/0014A61B5/0013A61B5/055A61B6/032A61B6/501A61B6/56A61B8/56A61B8/565G06F17/30247G06F19/00G06F19/321G16H50/70
    • An embodiment of the current invention includes a non-invasive imaging system, comprising: an imaging scanner suitable to generate an image representing a tissue region of a subject under observation, the tissue region having at least one substructure and the image comprising a plurality of image voxels; a signal processing system in communication with the imaging scanner to receive the imaging signal from the imaging scanner; and a data storage unit in communication with the signal processing system, wherein the data storage unit is configured to store: an atlas comprising spatial information of the at least one substructure in the tissue region, and a database comprising a plurality of pre-stored medical images representing the tissue region, and wherein the signal processing system is adapted to: identify, based on the atlas and for each of the at least one substructure, a corresponding portion of image voxels in the image; provide a computed quantification of the corresponding portion of image voxels for each of the at least one substructure of the tissue region by performing spatial filtering on the image; and search the database to provide at least one selected medical image from the plurality of pre-stored medical images, the at least one selected medical image having a corresponding quantification that is substantially similar to the computed quantification.
    • 本发明的一个实施例包括一种非侵入性成像系统,包括:成像扫描仪,其适于产生表示观察对象的组织区域的图像,所述组织区域具有至少一个子结构,并且所述图像包括多个图像 体素 与成像扫描仪通信的信号处理系统,以从成像扫描仪接收成像信号; 以及与所述信号处理系统通信的数据存储单元,其中所述数据存储单元被配置为存储:包括所述组织区域中的所述至少一个子结构的空间信息的图集,以及包括多个预先存储的医疗 表示组织区域的图像,并且其中所述信号处理系统适于:基于所述图集并且针对所述至少一个子结构中的每一个识别所述图像中的图像体素的相应部分; 通过对图像执行空间滤波来提供组织区域的至少一个子结构中的每一个的图像体素的相应部分的计算定量; 并且搜索所述数据库以从所述多个预先存储的医学图像中提供至少一个所选择的医学图像,所述至少一个所选择的医学图像具有与所计算的定量基本相似的相应量化。