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1. 发明申请

US20100030355A1 METHODS OF CREATING CUSTOMIZED BEVERAGE PRODUCTS 有权
标题翻译：创造定制饮料产品的方法
公开(公告)号：US20100030355A1
公开(公告)日：2010-02-04
申请号：US12365666
申请日：2009-02-04
申请人： Gerard E. Insolia , Hubertus Ulrich Schubert , James E. Goldman , Fred F. Sadeghi , Nilang Patel , Brock Kolls
发明人： Gerard E. Insolia , Hubertus Ulrich Schubert , James E. Goldman , Fred F. Sadeghi , Nilang Patel , Brock Kolls
IPC分类号： G05D11/02 , G06Q30/00 , G06Q50/00 , G06Q20/00 , G06F17/00 , G05D7/06
CPC分类号： G06Q50/04 , G06Q30/0601 , G06Q30/0603 , Y02P90/30
摘要： A method of creating customized beverage products includes providing a multiple stream filing system suited for producing an array of beverage products. The method also includes receiving an order for a customized beverage product from the array of beverage products. The order indicates at least one characteristic of the customized beverage product. The at least one characteristic comprises one or more of the following: a beverage formulation, a beverage additive, a package size, a package shape, or label content. The method further includes instructing the multiple stream filling system to produce the customized beverage product. The multiple stream filing system produces the customized beverage product without performing an operation to reduce contamination of the customized beverage product with ingredients from a previously produced beverage product.
摘要翻译：创建定制饮料产品的方法包括提供适合于生产饮料产品阵列的多流文件系统。该方法还包括从饮料产品阵列接收定制的饮料产品的订单。该订单指示定制饮料产品的至少一个特征。所述至少一个特征包括以下中的一种或多种：饮料配方，饮料添加剂，包装尺寸，包装形状或标签含量。该方法还包括指示多流灌装系统产生定制的饮料产品。多流文件系统产生定制的饮料产品，而不进行操作，以减少来自先前生产的饮料产品的成分的定制饮料产品的污染。

2. 发明申请

US20090320617A1 Device and Method for the Adjustment of a Temperature of a Liquid 审中-公开
标题翻译：用于调节液体温度的装置和方法
公开(公告)号：US20090320617A1
公开(公告)日：2009-12-31
申请号：US12553827
申请日：2009-09-03
申请人： Roger Sandoz , Frank Ulrich Schubert , Hans-Rudolf Bachmann , Renato Baumann
发明人： Roger Sandoz , Frank Ulrich Schubert , Hans-Rudolf Bachmann , Renato Baumann
IPC分类号： G01N1/10
CPC分类号： B01L7/00 , B01L3/50851 , B01L2300/1872
摘要： A device and a method for the adjustment of a temperature of a liquid which is contained in one or more sample vessels are specified, a control unit and a temperature adjustment unit being provided, which acts on the liquid contained in the sample vessels. Furthermore, the control unit is operatively connected to the temperature adjustment unit. The liquid to be analyzed contains absorption elements in order to accelerate the temperature adjustment in the liquid to be analyzed.
摘要翻译：指定用于调节一个或多个样品容器中包含的液体的温度的装置和方法，提供对作用于样品容器中的液体的控制单元和温度调节单元。此外，控制单元可操作地连接到温度调节单元。待分析的液体含有吸收元件，以加速待分析液体中的温度调节。

3. 发明申请

US20060048570A1 Rod-shaped element for liquid level detection and corresponding device for liquid level detection 失效
标题翻译：用于液位检测的棒状元件和用于液位检测的相应装置
公开(公告)号：US20060048570A1
公开(公告)日：2006-03-09
申请号：US11178571
申请日：2005-07-11
申请人： Heribert Eglauer , Gerhard Schlager , Uwe Kolb , Ulrich Schubert
发明人： Heribert Eglauer , Gerhard Schlager , Uwe Kolb , Ulrich Schubert
IPC分类号： G01F23/24 , H01R11/01 , H01R4/60
CPC分类号： G01F23/242 , G01F23/24 , G01N2035/1025
摘要： A metal rod-shaped element for a liquid detecting device is essentially cylindrical and has first and second ends. In at least one length, starting from the second end, the element has an isolating coating and an electrode strip is provided which extends along a longitudinal axis of the element. The electrode strip is not electrically connected to the element and the strip comprises a high impedance material. Two flattened sections are provided where the metal of the element lies openly. In a cross sectional view the electrode strip is situated between the two flattened sections. A first contact mechanism is provided in order to establish, in the range of the first end, an electrical contact to the rod-shaped element, and a second contact mechanism is provided in order to establish, within the range of the first end, an electrical contact to the electrode strip.
摘要翻译：用于液体检测装置的金属棒状元件基本上是圆柱形的并且具有第一和第二端。在至少一个长度上，从第二端开始，元件具有隔离涂层，并且提供沿着元件的纵向轴线延伸的电极条。电极条不与元件电连接，并且条带包括高阻抗材料。提供两个扁平部分，其中元件的金属公开地放置。在横截面图中，电极条位于两个平坦部分之间。提供第一接触机构，以在第一端的范围内建立与杆状元件的电接触，并且提供第二接触机构，以便在第一端的范围内建立一个电接触到电极条。

4. 发明申请

US20050203029A1 Agents for treating flaviviridaeinfections 审中-公开
标题翻译：用于治疗黄病毒感染的药剂
公开(公告)号：US20050203029A1
公开(公告)日：2005-09-15
申请号：US10510355
申请日：2003-04-04
申请人： Ulrich Schubert , Hans Will , Huseyin Sirma
发明人： Ulrich Schubert , Hans Will , Huseyin Sirma
IPC分类号： A61K31/11 , A61K31/16 , A61K31/69 , A61K38/06 , A61P31/12 , A61K31/366 , A61K38/04
CPC分类号： A61K31/69 , A61K31/11 , A61K31/16 , A61K38/06
摘要： The invention relates to agents for the treatment, therapy and inhibition of Flaviviridae virus infections, which agents comprise proteasome inhibitors as the active component. The agents which are used for inhibiting the release, maturation and replication of Flaviviridae comprise, as the active component in pharmaceutical preparations, substance classes which share the common property of inhibiting the 26S proteasome in cells. These substance classes include, in particular, proteasome inhibitors which affect the activities of the ubiquitin/proteasome pathway, in particular the enzymic activities of the 26S and the 20S proteasome complex. The application of the invention lies in the antiviral therapy of Flaviviridae infections, especially in preventing the establishment and maintenance of a chronic hepatitis C virus infection and a hepatopathogenesis which is associated therewith.
摘要翻译：本发明涉及用于治疗，治疗和抑制黄病毒科病毒感染的药剂，该药物包含作为活性成分的蛋白酶体抑制剂。用于抑制黄病毒科的释放，成熟和复制的药物包含作为药物制剂中的活性成分的具有抑制细胞中26S蛋白酶体的共同性质的物质类别。这些物质类别特别包括影响泛素/蛋白酶体途径的活性的蛋白酶体抑制剂，特别是26S和20S蛋白酶体复合物的酶活性。本发明的应用在于黄病毒科感染的抗病毒治疗，特别是在预防慢性丙型肝炎病毒感染的建立和维持以及与之相关的肝癌发病。

5. 发明授权

US06921513B2 System for processing samples in a multichamber arrangement 失效
标题翻译：用于在多室安排中处理样品的系统
公开(公告)号：US06921513B2
公开(公告)日：2005-07-26
申请号：US09738385
申请日：2000-12-16
申请人： Frank Ulrich Schubert , Udo Eichenlaub , Armin Tgetgel
发明人： Frank Ulrich Schubert , Udo Eichenlaub , Armin Tgetgel
IPC分类号： G01N35/10 , B01J3/02 , B01J4/00 , B01L3/00 , G01N35/00 , B01L3/02 , B32B27/04 , G01N1/10 , G01N21/00
CPC分类号： B01L3/5085 , G01N35/1065 , G01N2035/00277 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： System for processing samples, in particular samples containing nucleic acids comprising a multichamber arrangement the chambers of which are used to receive liquids and it also concerns a pipetting device for removing liquids from the chambers and/or dispensing liquid into the chambers, wherein the system has a contamination protection which can move relative to the multichamber arrangement and which prevents contamination of an adjacent second chamber with liquid from the first chamber during a pipetting operation in the first chamber, by preventing discharge of fluid droplets from the first chamber into the second chamber by at least partially covering the first chamber.
摘要翻译：用于处理样品的系统，特别是含有核酸的样品，所述核酸包括其室用于接收液体的多室布置，并且还涉及用于从室中去除液体和/或将液体分配到室中的移液装置，其中系统具有可以相对于多室配置移动的污染保护，并且通过防止流体液滴从第一室排入第二室中，在第一室中的移液操作期间防止邻近的第二室与来自第一室的液体的污染至少部分地覆盖第一室。

6. 发明授权

US06919175B1 System for releasing and isolating nucleic acids 失效
标题翻译：释放和分离核酸的系统
公开(公告)号：US06919175B1
公开(公告)日：2005-07-19
申请号：US09558038
申请日：2000-04-26
申请人： Gerhard Bienhaus , Ulrich Schubert , Uwe Kolb , Burkhard Stolz , Manfred Pasch
发明人： Gerhard Bienhaus , Ulrich Schubert , Uwe Kolb , Burkhard Stolz , Manfred Pasch
IPC分类号： C07H21/04 , C12N1/20 , C12N15/00 , C12N15/10 , C12N15/63 , C12Q1/68
CPC分类号： C12N15/1013
摘要： A procedure for the release and isolation of nucleic acids from biological compartments of a sample always uses an instrument that can hold one or more sample processsing vessels, maintain the sample processing vessels at a constant temperature, shake the sample processing vessels and separate magnetic particles by means of magnetic force. This system greatly simplifies the isolation of nucleic acids.
摘要翻译：用于从样品的生物室释放和分离核酸的程序总是使用可以容纳一个或多个样品处理容器的仪器，将样品处理容器保持在恒定温度，摇动样品处理容器并将磁性颗粒分开磁力手段该系统大大简化了核酸的分离。

7. 发明授权

US6127306A Organofunctionalized aerogels 失效
标题翻译：有机官能化气凝胶
公开(公告)号：US6127306A
公开(公告)日：2000-10-03
申请号：US43054
申请日：1998-07-06
申请人： Nicola Husing , Ulrich Schubert
发明人： Nicola Husing , Ulrich Schubert
IPC分类号： B01J21/08 , B01J31/02 , B01J31/16 , B01J31/20 , B01J31/24 , B01J37/03 , C01B33/158 , C09K5/06 , B01J31/00 , C01B33/12
CPC分类号： C09K5/063 , B01J21/08 , B01J31/1633 , B01J31/20 , B01J31/2404 , B01J37/033 , C01B33/1585 , B01J2531/822
摘要： The invention relates to aerogels containing functional residues of the formula (I)--Y--Z, wherein Y is a straight-chained or branched alkylene group with 1 to 22 carbon atoms; Z is halogen, pseudohalogen, SR.sup.1, PR.sup.2 R.sup.3, colorant residue or metal complex residue; R.sup.1 is H, a straight-chained or branched alkyl group with 1 to 22 carbon atoms or an aryl group with 4 to 10 carbon atoms; and R.sup.2 and R.sup.3 are identical or different, a straight-chained or branched alkyl group with 1 to 22 carbon atoms, or an aryl group with 4 to 10 carbon atoms. The aerogels are suitable, for example, as catalyst stayes and/or sensors. They can be obtained by metal alcoholates and metal alcoholates in which at least one alcoholate residue is replaced by the --Y--Z group being converted into a lyogel by hydrolysis and condensation, and subsequently being dried.
摘要翻译： PCT No.PCT / EP96 / 03999 Sec。 371日期：1998年7月6日 102（e）1998年7月6日PCT PCT 1996年9月12日PCT公布。公开号WO97 / 10178 日期：1997年3月20日本发明涉及含有式（I）-Y-Z的功能性残基的气凝胶，其中Y是具有1至22个碳原子的直链或支链亚烷基; Z是卤素，假卤素，SR1，PR2R3，着色剂残基或金属络合物残基; R1是H，具有1至22个碳原子的直链或支链烷基或具有4至10个碳原子的芳基; R2和R3相同或不同，具有1至22个碳原子的直链或支链烷基或具有4至10个碳原子的芳基。气凝胶例如作为催化剂残留物和/或传感器是合适的。它们可以通过金属醇化物和金属醇化物获得，其中至少一个醇化物残基被-Y-Z基团替代，通过水解和缩合转化成lyogel，随后被干燥。

8. 发明授权

US09085449B2 Aseptic dosing system 有权
标题翻译：无菌配药系统
公开(公告)号：US09085449B2
公开(公告)日：2015-07-21
申请号：US12719028
申请日：2010-03-08
申请人： James E. Goldman , Hubertus Ulrich Schubert , Peter Simpson , Marcelo Silvado
发明人： James E. Goldman , Hubertus Ulrich Schubert , Peter Simpson , Marcelo Silvado
IPC分类号： B67C3/20 , B65B3/04 , B65B55/12
CPC分类号： B67C3/208 , B65B3/04 , B65B55/12 , B65B2220/14
摘要： The present application provides an aseptic dosing system for dispensing a micro-ingredient. The aseptic dosing system may include a micro-ingredient source adapted to dispense the micro-ingredient, a sterilizer downstream of the micro-ingredient source configured to sterilize the micro-ingredient, and a nozzle downstream of the sterilizer configured to reconstitute the micro-ingredient in or downstream thereof.
摘要翻译：本申请提供了用于分配微量成分的无菌计量系统。无菌剂量系统可以包括适于分配微量成分的微量成分源，微量成分源下游的消毒剂，其构造成对微量成分灭菌;以及灭菌器下游的喷嘴，其配置成重构微量成分在其中或下游。

9. 发明申请

US20120269797A1 METHOD FOR INHIBITING THE MATURATION OF DENDRITIC CELLS 审中-公开
标题翻译：抑制细胞成熟的方法
公开(公告)号：US20120269797A1
公开(公告)日：2012-10-25
申请号：US13384024
申请日：2010-07-15
申请人： Ulrich Schubert , Elisabeth Zinser , Alexander Steinkasserer
发明人： Ulrich Schubert , Elisabeth Zinser , Alexander Steinkasserer
IPC分类号： A61K38/55 , C07H15/24 , A61K31/704 , C07D207/28 , A61K31/4015 , C07K5/083 , C07F5/04 , A61K31/436 , A61K31/5377 , A61K39/395 , A61P37/08 , A61P11/06 , A61P37/06 , A61P37/00 , A61P21/04 , A61P25/00 , A61P1/00 , A61P19/04 , A61P17/00 , A61P29/00 , A61P3/10 , A61P1/04 , A61P17/06 , C07K5/103
CPC分类号： A61K31/69 , A61K31/00
摘要： Proteasome inhibitors (PI) are used for inhibiting the maturation of dendritic cells (DZ) and thus in the treatment or the prophylaxis of allergies, asthma, tissue or transplant rejection or autoimmune diseases. The concentration of the proteasome inhibitors lies preferably in the range of 10 nM to 10 μM, based on the peripheral blood or the cytoplasm.
摘要翻译：蛋白酶体抑制剂（PI）用于抑制树突状细胞（DZ）的成熟，从而用于治疗或预防过敏，哮喘，组织或移植排斥或自身免疫性疾病。基于外周血或细胞质，蛋白酶体抑制剂的浓度优选在10nM至10μM的范围内。

10. 发明申请

US20080293036A1 Monoclonal Antibodies to Hiv-1 and Methods of Using Same 有权
标题翻译： Hiv-1的单克隆抗体及其使用方法
公开(公告)号：US20080293036A1
公开(公告)日：2008-11-27
申请号：US11630880
申请日：2005-06-22
申请人： Jeffrey B. Kopp , Terence M. Phillips , Ulrich Schubert , John Yewell
发明人： Jeffrey B. Kopp , Terence M. Phillips , Ulrich Schubert , John Yewell
IPC分类号： C12Q1/70 , C07K16/18 , C12N5/06
CPC分类号： C07K16/1072 , G01N33/56988 , G01N2333/163
摘要： The present invention provides monoclonal antibodies to HIV-1 Vpr and hybridoma cell lines that produce the monoclonal antibodies to HIV-1 Vpr. Methods for use of such antibodies in the detection of HIV-1 infection are also provided.
摘要翻译：本发明提供了针对HIV-1Vpr的单克隆抗体和产生HIV-1Vpr单克隆抗体的杂交瘤细胞系。还提供了在检测HIV-1感染中使用这种抗体的方法。

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