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1. 发明申请

US20180120299A1 TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER 审中-公开
公开(公告)号：US20180120299A1
公开(公告)日：2018-05-03
申请号：US15529936
申请日：2015-11-27
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD. , OSAKA UNIVERSITY
发明人： Takahiro NISHIBU , Naoko IMAWAKA , Ken NARUSE , Rikinari HANAYAMA
IPC分类号： G01N33/50 , C07K1/14 , C07K17/02 , G01N33/543 , G01N33/68
摘要： The invention provides a carrier and a method for obtaining, removing, or detecting extracellular membrane vesicle or virus present in a sample. In particular, the invention provides (a) a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; (b) a method for obtaining the extracellular membrane vesicle or the virus in the sample; (c) a method for removing the extracellular membrane vesicle or the virus in the sample; (d) a method for detecting the extracellular membrane vesicle or the virus in the sample; (e) a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and f) a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier.

2. 发明授权

US09952235B2 Standard solution for use in analysis of amino acids in plasma 有权
公开(公告)号：US09952235B2
公开(公告)日：2018-04-24
申请号：US15450135
申请日：2017-03-06
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD. , AJINOMOTO CO., INC.
发明人： Masako Hayakawa , Kazutaka Shimbo , Hiroo Yoshida
IPC分类号： G01N33/96 , G01N33/68 , G01N30/04
CPC分类号： G01N33/96 , G01N33/6806 , G01N33/6848 , G01N2030/042 , G01N2496/80 , Y10T436/105831 , Y10T436/106664
摘要： An external standard solution for use in the analysis of amino acid in plasma, containing, (1) at least one amino acid selected from the following components A, at a concentration of 0.0007 M to 0.49 M, and (2) (i) at least one amino acid selected from the following components B, at a concentration of 0.2 to 0.9 times of the lowest-concentration amino acid among the amino acids selected from components A, (ii) at least one amino acid selected from the following components C, at a concentration of 0.1 to 0.4 times of the lowest-concentration amino acid among amino acids selected from the components A, or (iii) at least one amino acid selected from the following components D, at a concentration of 0.05 to 0.2 times of the lowest-concentration amino acid among amino acids selected from the components A; [Components A] valine, glycine, alanine and glutamine [Components B] serine, proline, threonine, taurine, leucine, isoleucine, lysine, histidine, phenylalanine and tyrosine [Components C] asparagine, ornithine, arginine and tryptophan [Components D] glutamic acid, methionine, citrulline and cystine.

3. 发明申请

US20170331154A1 MAGNESIUM-CONTAINING ELECTROLYTIC SOLUTION 审中-公开
公开(公告)号：US20170331154A1
公开(公告)日：2017-11-16
申请号：US15529902
申请日：2015-11-27
申请人： Wako Pure Chemical Industries, Ltd.
发明人： Kazuhiko SATO , Takahiro KIYOSU , Hironori MIZUTA , Goro MORI , Kuniaki OKAMOTO
IPC分类号： H01M10/0568 , H01M4/38 , H01M10/054
CPC分类号： H01M10/0568 , C07F3/02 , C07F5/064 , C07F7/0836 , C07F19/005 , H01M4/381 , H01M10/054 , H01M10/056 , H01M10/0567 , H01M10/0569 , H01M10/365 , H01M2300/0025 , Y02E60/13
摘要： It is an object of the present invention to provide an electrolytic solution having high oxidation decomposition potential, where dissolution and deposition of magnesium proceed repeatedly and stably, using a non-nucleophilic alkoxide-type magnesium salt.The present invention relates to (1) an electrolytic solution for a magnesium battery comprising a mixture of a compound represented by the following general formula (I), a Lewis acid and a solvent: (2) an electrochemical device comprising the electrolytic solution, a positive electrode and a negative electrode, and (3) a compound represented by the following general formula (I′):

4. 发明授权

US09803161B2 Cleaning agent for semiconductor substrates and method for processing semiconductor substrate surface 有权
公开(公告)号：US09803161B2
公开(公告)日：2017-10-31
申请号：US14397364
申请日：2013-04-26
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD.
发明人： Hiromi Kawada , Hironori Mizuta , Tsuneaki Maesawa
IPC分类号： C11D7/50 , C11D11/00 , C11D7/36 , H01L21/02 , C11D7/32 , H01L21/768 , H01L21/3105 , H01L21/321
CPC分类号： C11D11/0047 , C11D7/3218 , C11D7/36 , H01L21/0206 , H01L21/02068 , H01L21/02074 , H01L21/31055 , H01L21/3212 , H01L21/7684
摘要： A cleaning agent is provided for a semiconductor substrate superior in corrosion resistance of a tungsten wiring or a tungsten alloy wiring, and superior in removal property of polishing fines (particle) such as silica or alumina, remaining at surface of the semiconductor substrate, in particular, at surface of a silicon oxide film such as a TEOS film, after a chemical mechanical polishing process; and a method for processing a semiconductor substrate surface. A cleaning agent for a semiconductor substrate is to be used in a post process of a chemical mechanical polishing process of the semiconductor substrate having a tungsten wiring or a tungsten alloy wiring, and a silicon oxide film, comprising (A) a phosphonic acid-based chelating agent, (B) a primary or secondary monoamine having at least one alkyl group or hydroxyalkyl group in a molecule and (C) water, wherein a pH is over 6 and below 7.

5. 发明申请

US20170261524A1 STANDARD SOLUTION FOR USE IN ANALYSIS OF AMINO ACIDS IN PLASMA 审中-公开
公开(公告)号：US20170261524A1
公开(公告)日：2017-09-14
申请号：US15450135
申请日：2017-03-06
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD. , AJINOMOTO CO., INC.
发明人： Masako HAYAKAWA , Kazutaka SHIMBO , Hiroo YOSHIDA
IPC分类号： G01N33/96 , G01N33/68
CPC分类号： G01N33/96 , G01N33/6806 , G01N33/6848 , G01N2030/042 , G01N2496/80 , Y10T436/105831 , Y10T436/106664
摘要： An external standard solution for use in the analysis of amino acid in plasma, containing, (1) at least one amino acid selected from the following components A, at a concentration of 0.0007 M to 0.49 M, and (2) (i) at least one amino acid selected from the following components B, at a concentration of 0.2 to 0.9 times of the lowest-concentration amino acid among the amino acids selected from components A, (ii) at least one amino acid selected from the following components C, at a concentration of 0.1 to 0.4 times of the lowest-concentration amino acid among amino acids selected from the components A, or (iii) at least one amino acid selected from the following components D, at a concentration of 0.05 to 0.2 times of the lowest-concentration amino acid among amino acids selected from the components A; [Components A] valine, glycine, alanine and glutamine [Components B] serine, proline, threonine, taurine, leucine, isoleucine, lysine, histidine, phenylalanine and tyrosine [Components C] asparagine, ornithine, arginine and tryptophan [Components D] glutamic acid, methionine, citrulline and cystine.

6. 发明授权

US09624535B2 Method for detecting methylated cytosine by using bisulfite reaction 有权
公开(公告)号：US09624535B2
公开(公告)日：2017-04-18
申请号：US14364545
申请日：2012-12-10
申请人： Wako Pure Chemical Industries, Ltd.
发明人： Yukinobu Hayashida , Naoyuki Yamamoto
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6858 , C12Q1/6806 , C12Q1/6827 , C12Q2523/125 , C12Q2527/125
摘要： The invention provides a method for converting non-methylated cytosine in a single-stranded DNA into uracil by a bisulfite reaction with a high conversion efficiency from non-methylated cytosine into uracil. The invention also provides a method for amplifying the single-stranded DNA in which non-methylated cytosine has been converted into uracil, as well as a method for detecting methylated cytosine in the single-stranded DNA.

7. 发明申请

US20170040612A1 BINDER FOR LITHIUM CELL 审中-公开
标题翻译：锂电池的粘合剂
公开(公告)号：US20170040612A1
公开(公告)日：2017-02-09
申请号：US15305521
申请日：2015-04-21
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD. , TOKYO UNIVERSITY OF SCIENCE FOUNDATION
发明人： Shinichi Komaba , Kiyofumi Yamagiwa , Shoko Aoki , Kuniaki Okamoto , Takahiro Kiyosu , Yasuyoshi Mori , Takatoshi Matsuura , Michihiko Sato
IPC分类号： H01M4/62 , H01M10/0525 , H01M4/38 , H01M4/134 , H01M4/587
CPC分类号： H01M4/622 , C08F220/06 , C08F220/18 , C08F220/56 , H01M4/134 , H01M4/36 , H01M4/38 , H01M4/386 , H01M4/587 , H01M4/62 , H01M10/0525 , C08F220/20 , C08F216/125 , C08F220/54 , C08F2220/286 , C08F2220/1841 , C08F220/24
摘要： It is an object of the present invention to provide an electrode having superior charge-discharge capacity, even in the case of using an active material containing silicon.The present invention relates to “a binder for a lithium cell comprises a polymer having a monomer unit derived from acrylic acid, and 1 to 2 kinds of monomer units derived from the compound shown by the general formula (I), the general formula (II), or the general formula (III), as constituents, and cross-linked by a cross-linking agent selected from the compounds described by the following general formulae [1] to [13], and the polymer described by the following general formula [14]”, “a composition for producing an electrode of a lithium cell comprising 1) an active material containing silicon, 2) a conductive assistant, and 3) the above-described binder for a cell”, and “an electrode for a lithium cell having 1) an active material containing silicon, 2) a conductive assistant, 3) the above-described binder for a cell, and (4) a current collector”.
摘要翻译：本发明涉及“锂电池用粘合剂”，其具有来自丙烯酸的单体单元的聚合物和由通式（I），通式（II）表示的化合物衍生的1〜2种单体单元，）或通式（III）作为组分，并且通过选自以下通式[1]至[13]所述的化合物的交联剂交联，并且由以下通式 [14]“，”锂电池电极的制造用组合物，其包含1）含有硅的活性物质，2）导电助剂，以及3）上述电池用粘合剂“，” 锂电池，其具有1）含硅的活性物质，2）导电助剂，3）上述电池用粘结剂，（4）集电体。

8. 发明授权

US09448244B2 Compound, and method for measuring iron concentration by using novel compound as chelate color former 有权
标题翻译：化合物和通过使用新型化合物作为螯合色素测量铁浓度的方法
公开(公告)号：US09448244B2
公开(公告)日：2016-09-20
申请号：US14433311
申请日：2013-10-15
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD.
发明人： Yoshikazu Fujita , Toshinari Ohashi , Naoyuki Yamamoto , Takashi Takagaki , Satoshi Hasaba
IPC分类号： C09B11/28 , G01N33/20 , G01N33/84 , C09B11/24 , G01N31/00 , C09B49/12 , G01N33/90 , G01N31/22
CPC分类号： G01N33/84 , C09B11/24 , C09B11/28 , C09B49/12 , G01N31/00 , G01N31/22 , G01N33/20 , G01N33/90
摘要： The present invention addresses the problem of providing a chelate color former which can measure the concentration of iron with high sensitivity and with low blank values when measuring the concentration of iron, and an iron concentration measurement method and kit that use this chelate color former. The present invention relates to: a compound represented by following formula [1] or a salt thereof wherein, R1 and R2 each independently represent —SO3H or —CO2H; an iron concentration measurement method in which the compound is used as a chelate color former, the compound is brought into contact with iron in a sample, and the concentration of iron in the sample is measured on the basis of the degree of resulting color development; and a kit to be used therein.
摘要翻译：本发明解决了提供一种螯合成色剂的问题，其可以测量铁的浓度时可以高灵敏度和低空白值测量铁的浓度，以及使用该螯合色素的铁浓度测量方法和试剂盒。本发明涉及：由下式[1]表示的化合物或其盐，其中R 1和R 2各自独立地表示-SO 3 H或-CO 2 H; 使用化合物作为螯合色素的铁浓度测定方法，使化合物与样品中的铁接触，并且根据得到的显色程度测量样品中的铁浓度; 和其中使用的试剂盒。

9. 发明申请

US20020042531A1 Novel monomer and a polymer obtained therefrom 失效
标题翻译：新型单体和由其获得的聚合物
公开(公告)号：US20020042531A1
公开(公告)日：2002-04-11
申请号：US09977364
申请日：2001-10-16
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD.
发明人： Motoshige Sumino
IPC分类号： C07F007/04 , C07C057/26 , C07C059/46
CPC分类号： C07C69/708 , C07C69/734 , C07D317/30 , C07D319/06 , C07D319/08 , C08F32/08 , C08G61/04 , G03F7/039
摘要： This invention relates to a monomer shown by the general formula null1null 1 (wherein Xnull is a cyclic hydrocarbon residue containing polymerizable double bond(s), which may have a substituent, Z is a spacer or a direct bond and R is a substituted alkyl or alkenyl group having one or two protected hydroxyl groups as substituent) and a polymer containing a segment derived from the above monomer. The said polymer is useful for a resist composition, etc. utilized in the production of semiconductor elements, etc. and the said monomer is useful as a starting material for the polymer, and a resist composition using the said polymer can remarkably advantageously be used as a resist material for ArF excimer laser beams which has been considered to be a valuable technology for exposure belonging to the coming generation.
摘要翻译：本发明涉及由通式[1]表示的单体（其中X'为含有可聚合双键的环状烃残基，可以具有取代基，Z为间隔基或直接键，R为取代基具有一个或两个保护的羟基作为取代基的烷基或烯基）和含有源自上述单体的链段的聚合物。所述聚合物可用于制备半导体元件等中使用的抗蚀剂组合物等，并且所述单体可用作聚合物的起始材料，并且使用所述聚合物的抗蚀剂组合物可显着有利地用作用于ArF准分子激光束的抗蚀材料，被认为是属于下一代的有意义的曝光技术。

10. 发明申请

US20010048916A1 Anti-protista preparation 失效
标题翻译：反主编准备
公开(公告)号：US20010048916A1
公开(公告)日：2001-12-06
申请号：US09839357
申请日：2001-04-23
申请人： WAKO PURE CHEMICAL INDUSTRIES, LTD
发明人： Hiroyuki Kato , Tadayoshi Yazaki , Tokihiko Maruyama
IPC分类号： A61L002/23 , A61K031/74 , A61K031/715 , A61K038/16
CPC分类号： C02F1/50 , A01N25/10 , A01N25/34 , A01N33/12 , A01N43/40 , A01N2300/00
摘要： The present invention provides a sustained-releasing anti-protista preparation, comprising using a water-insoluble or difficulty water soluble and water-wettable polymer compound which is solid at room temperature as a sustained-releasing substrate material, a method for a preparation of the sustained-releasing anti-protista preparation, comprising kneading a water-insoluble or difficulty water soluble and water-wettable polymer compound which is solid at room temperature with an anti-protista substance, and a sustained-releasing anti-protista preparation for a waterway, comprising using a water-insoluble or difficulty water soluble and water-wettable polymer compound which is solid at room temperature as a sustained-releasing substrate material.
摘要翻译：本发明提供一种持续释放抗原生物质制剂，其包括在室温下使用作为缓释底物的固体的水不溶性或难溶性水溶性和水可湿性聚合物化合物，制备持续释放抗原生物素制剂，其包括在室温下用抗原生物质混合水溶性或难溶性水溶性和水可湿性聚合物化合物，以及用于水路的持续释放抗原调节剂制剂，包括使用在室温下为固体的水不溶性或困难的水溶性和水可湿性聚合物化合物作为缓释基材。

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