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1. 发明申请

US20230050863A1 DICATIONIC FLUORESCENT DYES 有权
公开(公告)号：US20230050863A1
公开(公告)日：2023-02-16
申请号：US17756810
申请日：2020-12-07
申请人： Roche Molecular Systems, Inc.
发明人： Alexander Nierth
IPC分类号： C09K11/06 , C09B11/28 , C12Q1/6851 , G01N33/533
摘要： The present invention provides for water-soluble mono- and dicationic fluorescent dyes with the latter exhibiting stable fluorescence at elevated temperatures. The present invention also provides for methods for the production of the fluorescent dyes and for using these dyes in biological assays such as multiplexing qPCR and tissue staining.

2. 发明授权

US11415493B2 Detection of cells in a liquid sample 有权
公开(公告)号：US11415493B2
公开(公告)日：2022-08-16
申请号：US16085194
申请日：2017-03-17
申请人： DELTA INSTRUMENTS B.V.
发明人： Pierre Laurent Emond , Nancy Gail Perlmutter , James Willis Kreider
IPC分类号： G01N1/30 , C12Q1/04 , A01B5/02 , C12M1/34 , B01L3/00 , C09B11/28 , C09B23/04 , C12Q1/68 , G01N21/64
摘要： The invention relates to a method for counting cells, such as bacteria and/or somatic cells in liquid samples, such as in dairy products, preferably raw milk. Disclosed is a method comprising a combination of steps that apply dimeric nucleic acid dyes that normally do not penetrate cells (=cell-impermeant dyes), which are rendered cell-permeant by using the right combination of pH, buffer and temperature.

3. 发明授权

US11091644B2 Method for producing colorant composition, and colorant composition, colorant dispersion, photosensitive resin composition, color filter, liquid crystal display device produced using same 有权
公开(公告)号：US11091644B2
公开(公告)日：2021-08-17
申请号：US16485093
申请日：2018-06-05
申请人： LG CHEM, LTD.
发明人： Jongho Park , Dami Lee , Sanga Choi , Seung Jin Yang , Sang Gyun Park , Jae Joon Kim
IPC分类号： C09B11/28 , G03F7/033 , G02B5/20 , G02F1/1335 , G03F7/00
摘要： The present specification relates to a method for preparing a colorant composition comprising dissolving a first xanthene-based dye having the same number of positive charges and negative charges and a second xanthene-based dye having more negative charges than positive charges by one or more in a first solvent; and precipitating the dissolved first xanthene-based dye and the dissolved second xanthene-based dye in a second solvent, and a colorant composition, a colorant dispersion, a photosensitive resin composition, a color filter and a liquid crystal display device.

4. 发明申请

US20210101915A1 NEAR-IR GLUCOSE SENSORS 有权
公开(公告)号：US20210101915A1
公开(公告)日：2021-04-08
申请号：US16883355
申请日：2020-05-26
申请人： Profusa, Inc.
发明人： Soya GAMSEY , Viachaslau BERNAT , Alex KUTYAVIN , Jacob William CLARY , Sulolit PRADHAN
IPC分类号： C07F5/02 , C09B57/00 , C09B1/00 , A61B5/1459 , C09K11/06 , C09B23/01 , C09B23/08 , C09B69/00 , C09B11/28 , A61B5/145 , C09B23/04 , C09B57/02 , C09B11/24
摘要： Glucose-sensing luminescent dyes, polymers, and sensors are provided. Additionally, systems including the sensors and methods of using these sensors and systems are provided.

5. 发明授权

US10739330B2 Carbopyronone compounds useful as diagnostic adjuvants 有权
公开(公告)号：US10739330B2
公开(公告)日：2020-08-11
申请号：US16002991
申请日：2018-06-07
申请人： LIFE TECHNOLOGIES CORPORATION
发明人： Kyle Gee , Hee Chol Kang , Wenjun Zhou , Bradley Dubbels , Michael Olszowy , Michael O'Grady
IPC分类号： G01N33/50 , C09B11/28 , C07K16/28 , C07C309/61 , C07D471/04
摘要： Described herein are fluorescent compounds and methods and comprising these compounds. The compounds disclosed herein are carbopyronine reagents that fluoresce in the red portion of the UV/VIS spectrum and provide bright fluorescence intensity, uniform cell staining, and good retention within live cells as well as low toxicity toward cells.

6. 发明授权

US10261090B2 Glutathione-detecting fluorescent probe 有权
公开(公告)号：US10261090B2
公开(公告)日：2019-04-16
申请号：US15116661
申请日：2015-02-24
申请人： THE UNIVERSITY OF TOKYO
发明人： Yasuteru Urano , Mako Kamiya , Keitaro Umezawa , Masafumi Yoshida
IPC分类号： G01N33/68 , C09B11/08 , C09B11/24 , C09B11/28 , C09B19/00 , C09K11/07 , G01N21/64 , C07F7/08 , G01N33/58 , C09K11/06
摘要： [Problem] To provide the following: a novel fluorescent probe for detecting a compound, such as glutathione, that contains a —SH group; a detection method using said fluorescent probe; and a detection kit containing said probe.[Solution] A fluorescent probe for detecting a compound containing an —SH group, wherein the fluorescent probe comprises a compound represented by formula (I) or a salt thereof (In the formula, X represents Si(Ra)(Rb), Ge(Ra)(Rb), Sn(Ra)(Rb), C(Ra)(Rb), or O (wherein Ra and Rb each independently represent a hydrogen atom or alkyl group); R1 represents a hydrogen atom, or 1-4 identical or different substituents independently selected from the group consisting of a cyano group, alkyl group, carboxyl group, ester group, alkoxy group, amide group, and azide group, each of which may be optionally substituted; R2 represents a hydrogen atom, halogen atom, hydroxyl group, cyano group, or an alkyl group, alkynyl group, alkoxy group, aryl, or heteroaryl, each of which may be optionally substituted; R3 and R4 each independently represent a hydrogen atom or 1-3 identical or different substituents independently selected from the group consisting of a hydroxyl group, halogen atom, or an alkyl group, sulfo group, carboxyl group, ester group, amide group and azide group, each of which may be optionally substituted; R5, R6, R7 and R8 each independently represent a hydrogen atom or alkyl group, wherein, R5 or R6, respectively together with R3, may form a ring structure including the nitrogen atoms bonded thereto, or R7 or R8, respectively together with R4, may form a ring structure including the nitrogen atoms bonded thereto).

7. 发明申请

US20190094688A1 XANTHENE DYE 审中-公开
公开(公告)号：US20190094688A1
公开(公告)日：2019-03-28
申请号：US16204782
申请日：2018-11-29
申请人： FUJIFILM Corporation
发明人： Junichi ITOU , Akihiro HARA , Kazuya OOTA , Yushi KANEKO , Daisuke SASAKI
IPC分类号： G03F7/00 , G03F7/105 , G03F7/028 , G02B1/12 , C09B69/10 , C09B69/00 , C09B57/10 , C09B57/00 , C09B21/00 , G02B5/22 , C09B69/06 , C09B67/22 , C09B23/08 , C09B23/06 , C09B23/04 , C09B23/01 , C09B11/24 , C09B11/28 , C08F12/14 , G03F7/32 , G03F7/20 , G03F7/027
摘要： A colored composition of the present invention includes a dye compound having an anionic moiety including at least one of a structure represented by the following General Formula (A1), a structure represented by the following General Formula (A2), and a structure containing a boron atom, and a dye structure having a cationic moiety, in which the anionic moiety and the cationic moiety are bonded to each other via a covalent bond and present in the same molecule; a curable compound; and a solvent. (in General Formula (A1), R1 and R2 each independently represent —SO2— or —CO—) (in General Formula (A2), R3 represents —SO2— or —CO—; and R4 and R5 each independently represent —SO2—, —CO—, or —CN)

8. 发明授权

US10065959B2 Electronic device 有权
公开(公告)号：US10065959B2
公开(公告)日：2018-09-04
申请号：US14648409
申请日：2013-11-04
申请人： Merck Patent GmbH
发明人： Junyou Pan , Amir Hossain Parham , Rene Peter Scheurich , Thomas Rudolph
IPC分类号： H01L51/00 , C07D487/04 , C07D471/04 , C09B11/28 , C09B15/00 , C09B17/00 , C09B19/00 , C09B21/00 , C09B57/00 , C07D235/02 , C07D403/04 , C07D403/14 , C07D409/14 , C07D413/04 , C07D413/10 , C07D491/048 , C07D491/052 , C07D495/04 , C07D498/04 , C07D513/04 , C07D519/00 , H01L51/52 , H01L51/50
CPC分类号： C07D487/04 , C07D235/02 , C07D403/04 , C07D403/14 , C07D409/14 , C07D413/04 , C07D413/10 , C07D471/04 , C07D491/048 , C07D491/052 , C07D495/04 , C07D498/04 , C07D513/04 , C07D519/00 , C09B11/28 , C09B15/00 , C09B17/00 , C09B17/005 , C09B19/00 , C09B21/00 , C09B57/00 , H01L51/0067 , H01L51/0071 , H01L51/0072 , H01L51/5024 , H01L51/5076 , H01L51/5206 , H01L51/5221 , Y02E10/549
摘要： The present application relates to an electronic device comprising a heteroaromatic compound of a formula (I) as functional material, in particular as electron-transport material and as matrix material for emitter compounds.

9. 发明申请

US20180052105A1 SULFANE SULFUR-SELECTIVE FLUORESCENT PROBE 审中-公开
公开(公告)号：US20180052105A1
公开(公告)日：2018-02-22
申请号：US15552175
申请日：2016-01-21
申请人： The University of Tokyo
发明人： Kenjiro HANAOKA , Kazuhito SHIMAMOTO , Yasuteru URANO , Yoko TAKANO
IPC分类号： G01N21/64 , C09B11/28 , C12Q1/02 , G01N33/58 , G01N33/84
CPC分类号： G01N21/64 , C09B11/08 , C09B11/24 , C09B11/28 , C09B57/02 , C12Q1/02 , G01N21/3151 , G01N33/58 , G01N33/84 , G01N2021/3155 , G01N2021/6495
摘要： Fluorescent probes and their salts show sufficient solubility in water and detect sulfane sulfur in vivo. The fluorescent probes can have the following structure:

10. 发明授权

US09708244B2 Coloring material and method for producing the same 有权
公开(公告)号：US09708244B2
公开(公告)日：2017-07-18
申请号：US14436308
申请日：2012-10-18
申请人： DAI NIPPON PRINTING CO., LTD. , YAMAMOTO CHEMICALS, INC.
发明人： Masato Okada , Satoshi Kinoshita
IPC分类号： C07C211/58 , C09B11/28 , D06P1/42
CPC分类号： C07C211/58 , C09B11/28 , D06P1/42
摘要： The present invention is to provide a color material with excellent dyeing property and excellent heat resistance, and a method for producing the color material, which is able to obtain the color material with high purity and at high yield. Disclosed is a color material represented by the following general formula (I): (symbols in the general formula (I) are as described in the Description.)

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