专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08871777B2 Phenylpyrimidone compounds, the pharmaceutical compositions, preparation methods and uses thereof 有权
标题翻译：苯基嘧啶酮化合物，药物组合物，制备方法和用途
公开(公告)号：US08871777B2
公开(公告)日：2014-10-28
申请号：US13139156
申请日：2009-12-10
申请人： Zheng Liu , Jianfeng Li , Xiaojun Yang , Zhen Wang , Jinfeng Zhang , Yi Zhu , Guanghui Tian , Qing Jin , Jingkang Shen , Weiliang Zhu , Hualiang Jiang , Jingshan Shen
发明人： Zheng Liu , Jianfeng Li , Xiaojun Yang , Zhen Wang , Jinfeng Zhang , Yi Zhu , Guanghui Tian , Qing Jin , Jingkang Shen , Weiliang Zhu , Hualiang Jiang , Jingshan Shen
IPC分类号： A01N43/54 , A61K31/505 , C07D239/02 , C07D401/12 , C07D417/12 , C07D409/12 , C07D239/36 , C07D405/12 , C07D403/12 , C07H15/26
CPC分类号： A61K31/505 , C07D239/36 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07H15/26
摘要： The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the pharmaceutically acceptable salts or solvates thereof and to the pharmaceutical composition as well as the preparation method of the compounds. The compounds of formula I according to the present invention can effectively inhibit type V phosphodiesterase (PDE5), and thus can be used for the treatment of various vascular disorders, such as male erectile dysfunction, pulmonary hypertension and the like.
摘要翻译：本发明涉及一类苯基嘧啶酮化合物，药物组合物，其制备方法及用途。更具体地，本发明涉及一种下式I的苯基嘧啶酮化合物，其药学上可接受的盐或溶剂化物以及该药物组合物以及该化合物的制备方法。根据本发明的式I化合物可以有效抑制V型磷酸二酯酶（PDE5），从而可用于治疗各种血管疾病，如男性勃起功能障碍，肺动脉高压等。

2. 发明申请

US20130163873A1 Detecting Separator Lines in a Web Page 有权
标题翻译：检测网页中的分隔线
公开(公告)号：US20130163873A1
公开(公告)日：2013-06-27
申请号：US13812421
申请日：2010-07-30
申请人： Zhao Qingjie , Jianfeng Li , Ruisheng Xiong , Jingshan Shen , Weiliang Zhu , Hualiang Jiang , Jingkang Shen , Kyoung Tai No , Han Jo Kim , Ky-Youb Nam , Baik Lin Seong , Woo Jin Shin
发明人： Zhao Qingjie , Jianfeng Li , Ruisheng Xiong , Jingshan Shen , Weiliang Zhu , Hualiang Jiang , Jingkang Shen , Kyoung Tai No , Han Jo Kim , Ky-Youb Nam , Baik Lin Seong , Woo Jin Shin
IPC分类号： G06K9/00
CPC分类号： G06K9/00463 , C07D309/28
摘要： A system and method of detecting separator lines in a web page may include determining coordinates of visible web elements on a web page, generating an edge image of the web page based on the coordinates of the web elements, filtering edges belonging to non-separator line elements within the edge image, detecting horizontal lines within the edge image, detecting vertical lines within the edge image, and filtering short lines within the edge image. A system for detecting separator lines in a web page may include a memory device, and a processor communicatively coupled to the memory, in which the processor determines coordinates of visible web elements on a web page, generates an edge image of the web page based on the coordinates of the web elements, filters edges belonging to non-separator line elements within the edge image, detects horizontal lines within the edge image, detects vertical lines within the edge image, and filters short lines within the edge image.
摘要翻译：检测网页中的分隔线的系统和方法可以包括确定网页上的可视网页元素的坐标，基于网页元素的坐标生成网页的边缘图像，过滤属于非分隔线的边边缘图像内的元素，检测边缘图像内的水平线，检测边缘图像内的垂直线，以及过滤边缘图像内的短线。用于检测网页中的分隔线的系统可以包括存储器设备和通信地耦合到存储器的处理器，其中处理器确定网页上的可视网页元素的坐标，基于网页生成网页的边缘图像网页元素的坐标，属于边缘图像内的非分隔线元素的滤镜边缘，检测边缘图像内的水平线，检测边缘图像内的垂直线，并对边缘图像内的短线进行滤波。

3. 发明授权

US07529303B1 Methods and apparatus for determining transmission power levels 有权
标题翻译：用于确定发射功率电平的方法和装置
公开(公告)号：US07529303B1
公开(公告)日：2009-05-05
申请号：US11733672
申请日：2007-04-10
申请人： Alejandro Schwartzman , Paul Lafferty , Weiliang Zhu , Timothy Finan
发明人： Alejandro Schwartzman , Paul Lafferty , Weiliang Zhu , Timothy Finan
IPC分类号： H04B3/00 , H04N7/173
CPC分类号： H04N7/17309 , H04N17/004 , H04N21/42676 , H04N21/6118 , H04N21/6168
摘要： Methods and apparatus are provided for determining transmission power levels. The power characteristics of a cable modem family are determined by testing cable modems in a cable modem family with various downstream frequencies and transmission power levels to determine internal gain levels. The power characteristics of the cable modem family can then be stored in an efficient manner in each cable modem by using interpolation. The individual cable modem can then be characterized by testing the cable modem with a limited set of downstream frequencies and transmission power levels to determine an internal gain level offset for that particular cable modem. With the power characteristics table, internal gain level offset, and interpolation, transmission power levels can be determined during network operation when downstream frequencies and internal gain levels are known.
摘要翻译：提供了用于确定传输功率电平的方法和装置。电缆调制解调器系列的功率特性通过测试具有各种下行频率和发射功率电平的电缆调制解调器系列中的电缆调制解调器来确定内部增益水平来确定。然后可以通过使用插值以有效的方式将电缆调制解调器系列的功率特性存储在每个电缆调制解调器中。然后可以通过以有限的一组下行频率和发射功率电平测试电缆调制解调器来确定单个电缆调制解调器，以确定该特定电缆调制解调器的内部增益电平偏移。利用功率特性表，内部增益电平偏移和内插，当下游频率和内部增益电平已知时，可以在网络运行期间确定发射功率电平。

4. 发明授权

US09527849B2 Salt and polymorph of pyrazolopyrimidinone compound, and pharmaceutical composition containing the same, preparation method and use thereof 有权
标题翻译：吡唑并嘧啶酮化合物的盐和多晶型物，以及含有它们的药物组合物，其制备方法和用途
公开(公告)号：US09527849B2
公开(公告)日：2016-12-27
申请号：US14238790
申请日：2012-08-14
申请人： Jianfeng Li , Guanghui Tian , Zhen Wang , Jin Suo , Xiangrui Jiang , Zheng Liu , Xiaojun Yang , Zhu Xie , Xianguo Zhao , Weiliang Zhu , Hualiang Jiang , Jingshan Shen
发明人： Jianfeng Li , Guanghui Tian , Zhen Wang , Jin Suo , Xiangrui Jiang , Zheng Liu , Xiaojun Yang , Zhu Xie , Xianguo Zhao , Weiliang Zhu , Hualiang Jiang , Jingshan Shen
IPC分类号： C07D487/04 , A61K31/519 , A61P15/10 , A61P13/10 , A61P9/10 , A61P9/04 , A61P13/12 , A61P11/06 , A61P29/00 , A61P27/06 , A61P9/12
CPC分类号： C07D487/04 , C07B2200/13
摘要： The present invention relates to new salts of pyrazolopyrimidinone represented by formula (I), and pharmaceutically acceptable polymorph, solvate, hydrate, dehydrate, co-crystallization, anhydrous, or amorphous form thereof, the pharmaceutical compositions, and a pharmaceutical unit dosage form containing the same, wherein x represents organic or inorganic acids, preferable maleic acid, succinic acid, methanesulfonic acid, hydrochloric acid, etc. The invention further relates to co-crystals or complexes of compounds of pyrazolopyrimidinone and pharmaceutical compositions containing the same. The present invention also relates to a process for the preparation, use thereof and pharmaceutical preparation containing the salts or crystalline forms.
摘要翻译：本发明涉及由式（I）表示的吡唑并嘧啶酮的新盐及其药学上可接受的多晶型物，溶剂化物，水合物，脱水，共结晶，无水或无定形形式，药物组合物和含有相同的，其中x表示有机或无机酸，优选的马来酸，琥珀酸，甲磺酸，盐酸等。本发明还涉及吡唑并嘧啶酮化合物的共晶或络合物和含有它们的药物组合物。本发明还涉及其制备方法，使用方法和含有盐或结晶形式的药物制剂。

5. 发明申请

US20110301109A1 Phenylpyrimidone Compounds, the Pharmaceutical Compositions, Preparation Methods and Uses Thereof 有权
标题翻译：苯基嘧啶酮化合物，药物组合物，制备方法和用途
公开(公告)号：US20110301109A1
公开(公告)日：2011-12-08
申请号：US13139156
申请日：2009-12-10
申请人： Zheng Liu , Jianfeng Li , Xiaojun Yang , Zhen Wang , Jinfeng Zhang , Yi Zhu , Guanghui Tian , Qing Jin , Jingkang Shen , Weiliang Zhu , Hualiang Jiang , Jingshan Shen
发明人： Zheng Liu , Jianfeng Li , Xiaojun Yang , Zhen Wang , Jinfeng Zhang , Yi Zhu , Guanghui Tian , Qing Jin , Jingkang Shen , Weiliang Zhu , Hualiang Jiang , Jingshan Shen
IPC分类号： A61K31/7068 , C07H7/06 , C07D239/36 , A61K31/513 , C07H15/26 , C07D401/12 , C07D413/12 , A61K31/5377 , C07D401/14 , C07D405/12 , C07D409/12 , C07D417/12 , A61K31/55 , C07D413/10 , C07C257/18 , A61P11/06 , A61P15/00 , A61P13/08 , A61P15/10 , A61P9/12 , A61P9/00 , A61P29/00 , C07D403/12
CPC分类号： A61K31/505 , C07D239/36 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07H15/26
摘要： The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the pharmaceutically acceptable salts or solvates thereof and to the pharmaceutical composition as well as the preparation method of the compounds. The compounds of formula I according to the present invention can effectively inhibit type V phosphodiesterase (PDE5), and thus can be used for the treatment of various vascular disorders, such as male erectile dysfunction, pulmonary hypertension and the like.
摘要翻译：本发明涉及一类苯基嘧啶酮化合物，药物组合物，其制备方法及用途。更具体地，本发明涉及一种下式I的苯基嘧啶酮化合物，其药学上可接受的盐或溶剂化物以及该药物组合物以及该化合物的制备方法。根据本发明的式I化合物可以有效抑制V型磷酸二酯酶（PDE5），从而可用于治疗各种血管疾病，如男性勃起功能障碍，肺动脉高压等。

6. 发明申请

US20090182133A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS 审中-公开
标题翻译：苯并噻吩衍生物及其用作反病毒剂
公开(公告)号：US20090182133A1
公开(公告)日：2009-07-16
申请号：US12159570
申请日：2006-12-15
申请人： Chum Mok Puah , Weiliang Zhu , Jian Li , Lili Chen , Cheng Luo , Gang Chen , Zhili Zuo , Xiaomin Luo , Xu Shen , Kaixian Chen , Hualiang Jiang
发明人： Chum Mok Puah , Weiliang Zhu , Jian Li , Lili Chen , Cheng Luo , Gang Chen , Zhili Zuo , Xiaomin Luo , Xu Shen , Kaixian Chen , Hualiang Jiang
IPC分类号： C07H17/06 , C07D319/08
CPC分类号： A61K31/35 , C07D311/30 , C07D407/04 , C07H17/06
摘要： The invention relates to pharmaceutical compositions comprising benzopyranone derivatives for the treatment of Severe Acute Respiratory Syndrome (SARS).
摘要翻译：本发明涉及包含用于治疗严重急性呼吸综合征（SARS）的苯并吡喃酮衍生物的药物组合物。

7. 发明授权

US07221712B1 Methods and apparatus for determining transmission power levels 有权
标题翻译：用于确定发射功率电平的方法和装置
公开(公告)号：US07221712B1
公开(公告)日：2007-05-22
申请号：US10016032
申请日：2001-12-12
申请人： Alejandro Schwartzman , Paul Lafferty , Weiliang Zhu , Timothy Finan
发明人： Alejandro Schwartzman , Paul Lafferty , Weiliang Zhu , Timothy Finan
IPC分类号： H04B3/00 , H04N7/173
CPC分类号： H04N7/17309 , H04N17/004 , H04N21/42676 , H04N21/6118 , H04N21/6168
摘要： Methods and apparatus are provided for determining transmission power levels. The power characteristics of a cable modem family are determined by testing cable modems in a cable modem family with various downstream frequencies and transmission power levels to determine internal gain levels. The power characteristics of the cable modem family can then be stored in an efficient manner in each cable modem by using interpolation. The individual cable modem can then be characterized by testing the cable modem with a limited set of downstream frequencies and transmission power levels to determine an internal gain level offset for that particular cable modem. With the power characteristics table, internal gain level offset, and interpolation, transmission power levels can be determined during network operation when downstream frequencies and internal gain levels are known.
摘要翻译：提供了用于确定传输功率电平的方法和装置。电缆调制解调器系列的功率特性通过测试具有各种下行频率和发射功率电平的电缆调制解调器系列中的电缆调制解调器来确定内部增益水平来确定。然后可以通过使用插值以有效的方式将电缆调制解调器系列的功率特性存储在每个电缆调制解调器中。然后可以通过以有限的一组下行频率和发射功率电平测试电缆调制解调器来确定单个电缆调制解调器，以确定该特定电缆调制解调器的内部增益电平偏移。利用功率特性表，内部增益电平偏移和内插，当下游频率和内部增益电平已知时，可以在网络运行期间确定发射功率电平。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式