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1. 发明申请

US20090182133A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS 审中-公开
标题翻译：苯并噻吩衍生物及其用作反病毒剂
公开(公告)号：US20090182133A1
公开(公告)日：2009-07-16
申请号：US12159570
申请日：2006-12-15
申请人： Chum Mok Puah , Weiliang Zhu , Jian Li , Lili Chen , Cheng Luo , Gang Chen , Zhili Zuo , Xiaomin Luo , Xu Shen , Kaixian Chen , Hualiang Jiang
发明人： Chum Mok Puah , Weiliang Zhu , Jian Li , Lili Chen , Cheng Luo , Gang Chen , Zhili Zuo , Xiaomin Luo , Xu Shen , Kaixian Chen , Hualiang Jiang
IPC分类号： C07H17/06 , C07D319/08
CPC分类号： A61K31/35 , C07D311/30 , C07D407/04 , C07H17/06
摘要： The invention relates to pharmaceutical compositions comprising benzopyranone derivatives for the treatment of Severe Acute Respiratory Syndrome (SARS).
摘要翻译：本发明涉及包含用于治疗严重急性呼吸综合征（SARS）的苯并吡喃酮衍生物的药物组合物。

2. 发明申请

US20060142383A1 3D-Structure model of SARS coronavirus 3CL protease and anti-SARS drugs 失效
标题翻译： SARS冠状病毒3CL蛋白酶和抗SARS药物的3D结构模型
公开(公告)号：US20060142383A1
公开(公告)日：2006-06-29
申请号：US11293847
申请日：2005-12-02
申请人： Jianhua Shen , Hualiang Jiang , Xu Shen , Jianping Zuo , Xiaomin Luo , Donglu Bai , Jingkang Shen , Kaixian Chen , Chunshan Gui , Lili Chen , Jing Chen , Yifu Yang , Xianhan Zhuang , Yiming Yang , Xuchang He , Hong Liu , Bing Xiong , Haibin Luo , Tao Sun , Fei Ye
发明人： Jianhua Shen , Hualiang Jiang , Xu Shen , Jianping Zuo , Xiaomin Luo , Donglu Bai , Jingkang Shen , Kaixian Chen , Chunshan Gui , Lili Chen , Jing Chen , Yifu Yang , Xianhan Zhuang , Yiming Yang , Xuchang He , Hong Liu , Bing Xiong , Haibin Luo , Tao Sun , Fei Ye
IPC分类号： C12Q1/70 , G06F19/00 , C12N9/48 , A61K31/21 , A61K31/235 , A61K31/165
CPC分类号： C12N9/506 , A61K31/167
摘要： The present invention discloses 3D-structure of SARS-CoV Viral 3CL Protease obtained through molecular simulation. The 3D-structure is used as a drug target for screening the existing medical database CMC (Comprehensive Medicinal Chemistry, MDL Information System, Inc.), and a group of compounds which have the activity of inhibiting SARS-CoV virus 3CL Protease are found. Cinanserin was tested at molecular and viral levels, and it was found to be able to inhibit the SARS-CoV viral 3CL protease and SARS-CoV viruses. Cinanserin analogs were synthesized and tested at molecular and viral levels, they were found to be able to inhibit the SARS-CoV virus 3CL Protease and SARS-CoV viruses, and may be used for treating and/or preventing SARS-CoV virus infection.
摘要翻译：本发明公开了通过分子模拟获得的SARS-CoV病毒3CL蛋白酶的三维结构。使用3D结构作为筛选现有医学数据库CMC（Comprehensive Medicinal Chemistry，MDL Information System，Inc。）的药物靶点，并发现一组具有抑制SARS-CoV病毒3CL蛋白酶活性的化合物。在分子和病毒水平测试了Cinanserin，发现能够抑制SARS-CoV病毒3CL蛋白酶和SARS-CoV病毒。合成Cinanserin类似物并在分子和病毒水平进行测试，发现它们能够抑制SARS-CoV病毒3CL蛋白酶和SARS-CoV病毒，可用于治疗和/或预防SARS-CoV病毒感染。

3. 发明授权

US07662860B2 3D-structure model of SARS coronavirus 3CL protease and anti-SARS drugs 失效
标题翻译： SARS冠状病毒3CL蛋白酶和抗SARS药物的3D结构模型
公开(公告)号：US07662860B2
公开(公告)日：2010-02-16
申请号：US11293847
申请日：2005-12-02
申请人： Jianhua Shen , Hualiang Jiang , Xu Shen , Jianping Zuo , Xiaomin Luo , Donglu Bai , Jingkang Shen , Kaixian Chen , Chunshan Gui , Lili Chen , Jing Chen , Yifu Yang , Xianhan Zhuang , Yiming Yang , Xuchang He , Hong Liu , Bing Xiong , Haibin Luo , Tao Sun , Fei Ye
发明人： Jianhua Shen , Hualiang Jiang , Xu Shen , Jianping Zuo , Xiaomin Luo , Donglu Bai , Jingkang Shen , Kaixian Chen , Chunshan Gui , Lili Chen , Jing Chen , Yifu Yang , Xianhan Zhuang , Yiming Yang , Xuchang He , Hong Liu , Bing Xiong , Haibin Luo , Tao Sun , Fei Ye
IPC分类号： A61K31/165
CPC分类号： C12N9/506 , A61K31/167
摘要： The present invention discloses 3D-structure of SARS-CoV Viral 3CL Protease obtained through molecular simulation. The 3D-structure is used as a drug target for screening the existing medical database CMC (Comprehensive Medicinal Chemistry, MDL Information System, Inc.), and a group of compounds which have the activity of inhibiting SARS-CoV virus 3CL Protease are found. Cinanserin was tested at molecular and viral levels, and it was found to be able to inhibit the SARS-CoV viral 3CL protease and SARS-CoV viruses. Cinanserin analogs were synthesized and tested at molecular and viral levels, they were found to be able to inhibit the SARS-CoV virus 3CL Protease and SARS-CoV viruses, and may be used for treating and/or preventing SARS-CoV virus infection.
摘要翻译：本发明公开了通过分子模拟获得的SARS-CoV病毒3CL蛋白酶的三维结构。使用3D结构作为筛选现有医学数据库CMC（Comprehensive Medicinal Chemistry，MDL Information System，Inc。）的药物靶点，并发现一组具有抑制SARS-CoV病毒3CL蛋白酶活性的化合物。在分子和病毒水平测试了Cinanserin，发现能够抑制SARS-CoV病毒3CL蛋白酶和SARS-CoV病毒。合成Cinanserin类似物并在分子和病毒水平进行测试，发现它们能够抑制SARS-CoV病毒3CL蛋白酶和SARS-CoV病毒，可用于治疗和/或预防SARS-CoV病毒感染。

4. 发明授权

US08843917B1 Techniques for parallel drive upgrade while maintaining host accessibility 有权
标题翻译：并行驱动升级技术，同时保持主机可访问性
公开(公告)号：US08843917B1
公开(公告)日：2014-09-23
申请号：US13737295
申请日：2013-01-09
申请人： Shay Harel , Peter Puhov , Wayne Garrett , Lili Chen , Zhiqi Liu
发明人： Shay Harel , Peter Puhov , Wayne Garrett , Lili Chen , Zhiqi Liu
IPC分类号： G06F9/44 , G06F9/445
CPC分类号： G06F8/65 , G06F8/654
摘要： Described are techniques for performing a firmware update. A drive management object determines one or more physical drives matching criteria of a first received request. The drive management object sends to provision drive objects a second request to update firmware on physical drives. Firmware update processing is performed independently for each physical drive. Each provision drive object is associated with one of the physical drives. Firmware update processing for said one physical drive includes determining whether to perform the firmware update at a current point in time; in response to determining to perform the firmware update at the current point in time, performing preparation processing; notifying, upon completion of said preparation processing, a physical drive object associated with said one physical drive to download the firmware update to the one physical drive; and resuming I/O operations to the one physical drive upon successfully completing the firmware update.
摘要翻译：描述了用于执行固件更新的技术。驱动器管理对象确定符合第一接收请求的标准的一个或多个物理驱动器。驱动器管理对象向物理驱动器发送第二个更新固件的请求。每个物理驱动器独立执行固件更新处理。每个配置驱动对象与其中一个物理驱动器相关联。所述一个物理驱动器的固件更新处理包括确定是否在当前时间点执行固件更新; 响应于确定在当前时间点执行固件更新，执行准备处理; 在完成所述准备处理时通知与所述一个物理驱动器相关联的物理驱动对象，以将所述固件更新下载到所述一个物理驱动器; 并在成功完成固件更新后将I / O操作恢复到一个物理驱动器。

5. 发明授权

US08375385B1 Techniques for parallel drive upgrade while maintaining host accessibility 有权
标题翻译：并行驱动升级技术，同时保持主机可访问性
公开(公告)号：US08375385B1
公开(公告)日：2013-02-12
申请号：US13329685
申请日：2011-12-19
申请人： Shay Harel , Peter Puhov , Wayne Garrett , Lili Chen , Zhiqi Liu
发明人： Shay Harel , Peter Puhov , Wayne Garrett , Lili Chen , Zhiqi Liu
IPC分类号： G06F9/44 , G06F9/445
CPC分类号： G06F8/65 , G06F8/654
摘要： Described are techniques for performing a firmware update. A drive management object determines one or more physical drives matching criteria of a first received request. The drive management object sends to provision drive objects a second request to update firmware on physical drives. Firmware update processing is performed independently for each physical drive. Each provision drive object is associated with one of the physical drives. Firmware update processing for said one physical drive includes determining whether to perform the firmware update at a current point in time; in response to determining to perform the firmware update at the current point in time, performing preparation processing; notifying, upon completion of said preparation processing, a physical drive object associated with said one physical drive to download the firmware update to the one physical drive; and resuming I/O operations to the one physical drive upon successfully completing the firmware update.
摘要翻译：描述了用于执行固件更新的技术。驱动器管理对象确定符合第一接收请求的标准的一个或多个物理驱动器。驱动器管理对象向物理驱动器发送第二个更新固件的请求。每个物理驱动器独立执行固件更新处理。每个配置驱动对象与其中一个物理驱动器相关联。所述一个物理驱动器的固件更新处理包括确定是否在当前时间点执行固件更新; 响应于确定在当前时间点执行固件更新，执行准备处理; 在完成所述准备处理时通知与所述一个物理驱动器相关联的物理驱动对象，以将所述固件更新下载到所述一个物理驱动器; 并在成功完成固件更新后将I / O操作恢复到一个物理驱动器。

6. 发明授权

US07711136B2 Microphone array in housing receiving sound via guide tube 有权
标题翻译：外壳中的麦克风阵列通过导管接收声音
公开(公告)号：US07711136B2
公开(公告)日：2010-05-04
申请号：US11564869
申请日：2006-11-30
申请人： Ming Zhang , Bo Zhang , Lili Chen
发明人： Ming Zhang , Bo Zhang , Lili Chen
IPC分类号： H04R9/08
CPC分类号： H04R1/342 , H04R1/406 , H04R2499/11
摘要： An electronic device includes a housing, a plurality of microphones, and a plurality of guide tubes. The plurality of microphones are disposed in the housing. The plurality of guide tubes extend from the housing toward the plurality of microphones, whereby the plurality of microphones in the housing receives external sound via the guide tubes.
摘要翻译：电子设备包括壳体，多个麦克风和多个导管。多个麦克风设置在壳体中。多个引导管从壳体朝向多个麦克风延伸，由此壳体中的多个麦克风经由引导管接收外部声音。

7. 发明申请

US20080069389A1 MICROPHONE ARRAY IN HOUSING 有权
标题翻译：麦克风阵列住房
公开(公告)号：US20080069389A1
公开(公告)日：2008-03-20
申请号：US11771006
申请日：2007-06-29
申请人： Ming Zhang , Lili Chen , Bo Zhang
发明人： Ming Zhang , Lili Chen , Bo Zhang
IPC分类号： H04R17/02
CPC分类号： H04R1/406
摘要： An electronic device includes a circuit board, a first microphone module, and a second microphone module. The first microphone module includes a first omnidirectional microphone connected to the circuit board, a first boot also connected to the circuit board, and a first tube extending from the first boot. The second microphone module includes a second omnidirectional microphone connected to the circuit board, a second boot also connected to the circuit board, and a second tube extending from the second boot. The first and second omnidirectional microphones are identical, and the first and second boots are identical.
摘要翻译：电子设备包括电路板，第一麦克风模块和第二麦克风模块。第一麦克风模块包括连接到电路板的第一全向麦克风，还连接到电路板的第一引导器和从第一引导件延伸的第一管。第二麦克风模块包括连接到电路板的第二全向麦克风，还连接到电路板的第二引导器以及从第二引导件延伸的第二管。第一和第二全向麦克风是相同的，并且第一和第二靴子是相同的。

8. 发明申请

US20070127759A1 MICROPHONE ARRAY IN HOUSING RECEIVING SOUND VIA GUIDE TUBE 有权
标题翻译：麦克风阵列通过导管接收声音
公开(公告)号：US20070127759A1
公开(公告)日：2007-06-07
申请号：US11564869
申请日：2006-11-30
申请人： Ming Zhang , Bo Zhang , Lili Chen
发明人： Ming Zhang , Bo Zhang , Lili Chen
IPC分类号： H04R1/02
CPC分类号： H04R1/342 , H04R1/406 , H04R2499/11
摘要： An electronic device includes a housing, a plurality of microphones, and a plurality of guide tubes. The plurality of microphones are disposed in the housing. The plurality of guide tubes extend from the housing toward the plurality of microphones, whereby the plurality of microphones in the housing receives external sound via the guide tubes.
摘要翻译：电子设备包括壳体，多个麦克风和多个导管。多个麦克风设置在壳体中。多个引导管从壳体朝向多个麦克风延伸，由此壳体中的多个麦克风经由引导管接收外部声音。

9. 发明申请

US20070237345A1 METHOD FOR REDUCING PHASE VARIATION OF SIGNALS GENERATED BY ELECTRET CONDENSER MICROPHONES 审中-公开
标题翻译：减少由电子冷凝器微波产生的信号的相位变化的方法
公开(公告)号：US20070237345A1
公开(公告)日：2007-10-11
申请号：US11696308
申请日：2007-04-04
申请人： Bo Zhang , Ming Zhang , Lili Chen
发明人： Bo Zhang , Ming Zhang , Lili Chen
IPC分类号： H04R3/00 , H04R25/00
CPC分类号： H04R19/016 , H04R3/00
摘要： The invention provides a method for reducing phase variation of a signal generated by an electret condenser microphone. An error of a capacitance of the electret condenser microphone is reduced. An impedance of the electret condenser microphone is increased. A shunt resistance is added to the electret condenser microphone. A −3 dB cut-off frequency of the electret condenser microphone is lowered.
摘要翻译：本发明提供一种减少由驻极体电容麦克风产生的信号的相位变化的方法。驻极体电容麦克风的电容误差降低。驻极体电容麦克风的阻抗增加。对驻极体电容式麦克风加入并联电阻。驻极体电容麦克风的-3 dB截止频率降低。

10. 发明申请

US20070215298A1 Dual umbrella structure sunshade for vehicles 审中-公开
标题翻译：双伞结构遮阳篷车
公开(公告)号：US20070215298A1
公开(公告)日：2007-09-20
申请号：US11376852
申请日：2006-03-16
申请人： Lili Chen
发明人： Lili Chen
IPC分类号： B60J1/20
CPC分类号： B60J11/00
摘要： A sunshade for a motor vehicle supported by two umbrella structures, which are mounted by suction cups on the front windshield and rear window of the vehicle. Locking levers control the suction cups. The telescoping umbrella support structures elevate the sunshade spread out above the vehicle to shade the vehicle interior.
摘要翻译：用于由两个伞形结构支撑的机动车辆的遮阳罩，其由吸盘安装在车辆的前挡风玻璃和后窗上。锁定杆控制吸盘。伸缩式伞形支撑结构提升了在车辆上方展开的遮阳篷以遮蔽车辆内部。

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