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1. 发明申请

US20100274241A1 SURFACE ELECTRODE MULTIPLE MODE OPERATION 有权
标题翻译：表面电极多模式操作
公开(公告)号：US20100274241A1
公开(公告)日：2010-10-28
申请号：US12833843
申请日：2010-07-09
申请人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
发明人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/1477 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00196 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A surface electrode for ablating tissue is provided. The surface electrode comprises a base, a plurality of tissue penetrating needle electrodes extending from the surface of the base an adjustable distance, and an electrical interface coupled to the plurality of needle electrodes. The adjustability of the needle electrodes allows the depth that the needle electrodes penetrate through tissue to be adjusted.
摘要翻译：提供用于烧伤组织的表面电极。所述表面电极包括基底，从所述基底的表面延伸可调节距离的多个组织穿透针电极以及耦合到所述多个针电极的电接口。针电极的可调性允许针电极穿透组织的深度被调整。

2. 发明授权

US06979330B2 System for indirectly ablating tissue using implanted electrode devices 失效
标题翻译：使用植入电极器件间接消融组织的系统
公开(公告)号：US06979330B2
公开(公告)日：2005-12-27
申请号：US10387892
申请日：2003-03-13
申请人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
发明人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
IPC分类号： A61B18/14 , A61B19/00 , A61N1/06 , A61B18/18
CPC分类号： A61B18/1477 , A61B90/39 , A61B2018/143 , A61B2018/1432 , A61B2018/1495 , A61B2090/3987 , A61N1/06
摘要： Systems and methods are provided for ablating tissue by implanting a plurality of electrode devices within the tissue to be treated and exposing the implanted electrode devices with RF energy conveyed from a separate electrode device. In this manner, a greater region of tissue is ablated than what would normally be ablated with the separate electrode device. In addition, the implanted electrode devices can create a roadmap that allows the progress of the treatment to be managed during follow-ups. The implanted electrode devices can be variously delivered to the tissue, for example, by detaching the electrode devices from one or more delivery devices. For example, a core wire with an electrolytically detachable junction can be used to separate the electrode device from the core wire. Pusher rods with mechanically detachable junctions are also contemplated.
摘要翻译：提供了系统和方法，用于通过将待治疗的组织内的多个电极装置植入而烧蚀组织，并且用从单独的电极装置输送的RF能量暴露所述植入的电极装置。以这种方式，组织的较大区域比通常用单独的电极装置消融更多的区域被消融。此外，植入的电极装置可以创建允许在随访期间对治疗进展进行管理的路线图。植入的电极装置可以被不同地递送到组织，例如通过将电极装置从一个或多个递送装置分离。例如，可以使用具有电解可分离结的芯线来将电极装置与芯线分离。具有机械可拆卸接头的推杆也可以考虑。

3. 发明申请

US20100256633A1 METHOD FOR INDIRECTLY ABLATING TISSUE USING IMPLANTED ELECTRODE DEVICES 失效
标题翻译：用于使用植入式电极装置进行组织清除的方法
公开(公告)号：US20100256633A1
公开(公告)日：2010-10-07
申请号：US12818091
申请日：2010-06-17
申请人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
发明人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B90/39 , A61B2018/143 , A61B2018/1432 , A61B2018/1495 , A61B2090/3987 , A61N1/06
摘要： Methods are provided for ablating tissue by implanting a plurality of electrode devices within the tissue to be treated and exposing the implanted electrode devices with RF energy conveyed from a separate electrode device. In this manner, a greater region of tissue is ablated than what would normally be ablated with the separate electrode device. In addition, the implanted electrode devices can create a roadmap that allows the progress of the treatment to be managed during follow-ups. The implanted electrode devices can be variously delivered to the tissue, for example, by detaching the electrode devices from one or more delivery devices. For example, a core wire with an electrolytically detachable junction can be used to separate the electrode device from the core wire. Pusher rods with mechanically detachable junctions are also contemplated.
摘要翻译：提供了用于通过在待治疗的组织内植入多个电极装置并且用从单独的电极装置输送的RF能量暴露所述植入的电极装置来烧蚀组织的方法。以这种方式，组织的较大区域比通常用单独的电极装置消融更多的区域被消融。此外，植入的电极装置可以创建允许在随访期间对治疗进展进行管理的路线图。植入的电极装置可以被不同地递送到组织，例如通过将电极装置从一个或多个递送装置分离。例如，可以使用具有电解可分离结的芯线来将电极装置与芯线分离。具有机械可拆卸接头的推杆也可以考虑。

4. 发明授权

US07749219B2 Method for indirectly ablating tissue using implanted electrode device 有权
标题翻译：使用植入电极装置间接消融组织的方法
公开(公告)号：US07749219B2
公开(公告)日：2010-07-06
申请号：US11258417
申请日：2005-10-24
申请人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
发明人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B90/39 , A61B2018/143 , A61B2018/1432 , A61B2018/1495 , A61B2090/3987 , A61N1/06
摘要： Methods are provided for ablating tissue by implanting a plurality of electrode devices within the tissue to be treated and exposing the implanted electrode devices with RF energy conveyed from a separate electrode device. In this manner, a greater region of tissue is ablated than what would normally be ablated with the separate electrode device. In addition, the implanted electrode devices can create a roadmap that allows the progress of the treatment to be managed during follow-ups. The implanted electrode devices can be variously delivered to the tissue, for example, by detaching the electrode devices from one or more delivery devices. For example, a core wire with an electrolytically detachable junction can be used to separate the electrode device from the core wire. Pusher rods with mechanically detachable junctions are also contemplated.
摘要翻译：提供了用于通过在待治疗的组织内植入多个电极装置并且用从单独的电极装置输送的RF能量暴露所述植入的电极装置来烧蚀组织的方法。以这种方式，组织的较大区域比通常用单独的电极装置消融更多的区域被消融。此外，植入的电极装置可以创建允许在随访期间对治疗进展进行管理的路线图。植入的电极装置可以被不同地递送到组织，例如通过将电极装置从一个或多个递送装置分离。例如，可以使用具有电解可分离结的芯线来将电极装置与芯线分离。具有机械可拆卸接头的推杆也可以考虑。

5. 发明授权

US07455671B2 Surface electrode multiple mode operation 失效
标题翻译：表面电极多模式操作
公开(公告)号：US07455671B2
公开(公告)日：2008-11-25
申请号：US11867668
申请日：2007-10-04
申请人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
发明人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00196 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A surface electrode for ablating tissue is provided. The surface electrode comprises a base, a plurality of tissue penetrating needle electrodes extending from the surface of the base an adjustable distance, and an electrical interface coupled to the plurality of needle electrodes. The adjustability of the needle electrodes allows the depth that the needle electrodes penetrate through tissue to be adjusted.
摘要翻译：提供用于烧伤组织的表面电极。所述表面电极包括基底，从所述基底的表面延伸可调节距离的多个组织穿透针电极以及耦合到所述多个针电极的电接口。针电极的可调性允许针电极穿透组织的深度被调整。

6. 发明授权

US08753336B2 Method for indirectly ablating tissue using implanted electrode devices 失效
标题翻译：使用植入电极器件间接消融组织的方法
公开(公告)号：US08753336B2
公开(公告)日：2014-06-17
申请号：US12818091
申请日：2010-06-17
申请人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
发明人： Amy C. Kelly , Robert J. Garabedian , Steven K. Landreville
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B90/39 , A61B2018/143 , A61B2018/1432 , A61B2018/1495 , A61B2090/3987 , A61N1/06
摘要： Methods are provided for ablating tissue by implanting a plurality of electrode devices within the tissue to be treated and exposing the implanted electrode devices with RF energy conveyed from a separate electrode device. In this manner, a greater region of tissue is ablated than what would normally be ablated with the separate electrode device. In addition, the implanted electrode devices can create a roadmap that allows the progress of the treatment to be managed during follow-ups. The implanted electrode devices can be variously delivered to the tissue, for example, by detaching the electrode devices from one or more delivery devices. For example, a core wire with an electrolytically detachable junction can be used to separate the electrode device from the core wire. Pusher rods with mechanically detachable junctions are also contemplated.
摘要翻译：提供了用于通过在待治疗的组织内植入多个电极装置并且用从单独的电极装置输送的RF能量暴露所述植入的电极装置来烧蚀组织的方法。以这种方式，组织的较大区域比通常用单独的电极装置消融更多的区域被消融。此外，植入的电极装置可以创建允许在随访期间对治疗进展进行管理的路线图。植入的电极装置可以被不同地递送到组织，例如通过将电极装置从一个或多个递送装置分离。例如，可以使用具有电解可分离结的芯线来将电极装置与芯线分离。具有机械可拆卸接头的推杆也可以考虑。

7. 发明授权

US08109927B2 Surface electrode multiple mode operation 有权
标题翻译：表面电极多模式操作
公开(公告)号：US08109927B2
公开(公告)日：2012-02-07
申请号：US12833843
申请日：2010-07-09
申请人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
发明人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00196 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A surface electrode for ablating tissue is provided. The surface electrode comprises a base, a plurality of tissue penetrating needle electrodes extending from the surface of the base an adjustable distance, and an electrical interface coupled to the plurality of needle electrodes. The adjustability of the needle electrodes allows the depth that the needle electrodes penetrate through tissue to be adjusted.
摘要翻译：提供用于烧伤组织的表面电极。所述表面电极包括基底，从所述基底的表面延伸可调节距离的多个组织穿透针电极以及耦合到所述多个针电极的电接口。针电极的可调性允许针电极穿透组织的深度被调整。

8. 发明授权

US07182761B2 Ablation probe with temperature sensitive electrode array 失效
标题翻译：消融探头带温度敏感电极阵列
公开(公告)号：US07182761B2
公开(公告)日：2007-02-27
申请号：US10734648
申请日：2003-12-11
申请人： Robert J. Garabedian , Amy C. Kelly , Steven K. Landreville
发明人： Robert J. Garabedian , Amy C. Kelly , Steven K. Landreville
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B18/148 , A61B2017/00867 , A61B2018/00577 , A61B2018/143 , A61B2018/1432 , C08L2201/12
摘要： A medical probe assembly and method are provided for ablating tissue. The probe assembly comprises an elongated shaft and an electrode array mechanically coupled to the distal end of the shaft. The electrode array is configured to assume an outwardly curved shape, when exposed to a first temperature, and assume a pointed tip when exposed to a second temperature less than the first temperature. The first temperature is preferably greater than body temperature, e.g., equal to the tissue ablation temperature, and the second temperature is preferably less than a tissue ablation temperature, e.g., body temperature. In this manner, the pointed tip assumed by the electrode array facilitates introduction of the probe assembly through the tissue prior to the ablation process, while the outwardly curved shape assumed by the electrode array facilitates deployment of the electrode array within the tissue during the ablation process. The exposed needle electrodes also facilitate the visualization of the probe assembly under fluoroscopy. The probe assembly comprises an optional deployment member, which is configured to linearly expand when exposed to a third temperature, thereby displacing the electrode array.
摘要翻译：提供了用于烧蚀组织的医疗探针组件和方法。探针组件包括细长轴和机械耦合到轴的远端的电极阵列。当暴露于第一温度时，电极阵列构造成呈现向外弯曲的形状，并且当暴露于小于第一温度的第二温度时呈现尖端尖端。第一温度优选地大于体温，例如等于组织消融温度，并且第二温度优选小于组织消融温度，例如体温。以这种方式，由电极阵列假设的尖端有助于在消融过程之前通过组织引入探针组件，而由电极阵列假设的向外弯曲的形状有助于在消融过程期间电极阵列在组织内的展开。暴露的针电极还有助于荧光检查下探针组件的可视化。探针组件包括可选的展开构件，其构造成当暴露于第三温度时线性膨胀，从而移位电极阵列。

9. 发明授权

US06918907B2 Surface electrode multiple mode operation 失效
标题翻译：表面电极多模式操作
公开(公告)号：US06918907B2
公开(公告)日：2005-07-19
申请号：US10388143
申请日：2003-03-13
申请人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
发明人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
IPC分类号： A61B18/00 , A61B18/14 , A61B18/18
CPC分类号： A61B18/1477 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00196 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A surface electrode for ablating tissue is provided. The surface electrode comprises a base, a plurality of tissue penetrating needle electrodes extending from the surface of the base an adjustable distance, and an electrical interface coupled to the plurality of needle electrodes. The adjustability of the needle electrodes allows the depth that the needle electrodes penetrate through tissue to be adjusted.
摘要翻译：提供用于烧伤组织的表面电极。所述表面电极包括基底，从所述基底的表面延伸可调节距离的多个组织穿透针电极以及耦合到所述多个针电极的电接口。针电极的可调性允许针电极穿透组织的深度被调整。

10. 发明授权

US07771423B2 Surface electrode multiple mode operation 失效
标题翻译：表面电极多模式操作
公开(公告)号：US07771423B2
公开(公告)日：2010-08-10
申请号：US12271738
申请日：2008-11-14
申请人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
发明人： Amy C. Kelly , Steven K. Landreville , Robert J. Garabedian
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00196 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A surface electrode for ablating tissue is provided. The surface electrode comprises a base, a plurality of tissue penetrating needle electrodes extending from the surface of the base an adjustable distance, and an electrical interface coupled to the plurality of needle electrodes. The adjustability of the needle electrodes allows the depth that the needle electrodes penetrate through tissue to be adjusted.
摘要翻译：提供用于烧伤组织的表面电极。所述表面电极包括基底，从所述基底的表面延伸可调节距离的多个组织穿透针电极以及耦合到所述多个针电极的电接口。针电极的可调性允许针电极穿透组织的深度被调整。

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