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1. 发明授权

US6032076A Transintegumental power transformers with high permeability cores 失效
标题翻译：具有高磁导率核心的电力变压器
公开(公告)号：US6032076A
公开(公告)日：2000-02-29
申请号：US045432
申请日：1998-03-20
申请人： David Melvin , H. Thurman Henderson , Arthur J. Helmicki
发明人： David Melvin , H. Thurman Henderson , Arthur J. Helmicki
IPC分类号： A61F2/02 , A61N1/08 , A61N1/378 , A61N2/04 , A61N1/00
CPC分类号： A61N1/08 , A61F2250/0001 , A61N1/3787
摘要： Extra- to intra-corporeal power is provided by a transformer implanted at least partially within a defunctionalized intestinal pouch (or sack), such as an ileal pouch. The transformer includes a continuous loop magnetic core which is implanted within the pouch. The pouch itself includes a passageway permitting the secondary wiring to extend around the and through the magnetic core and through its central opening without entering the pouch providing intracorporeal current. Wire providing the primary windings extend from outside the body in through a stoma into the pouch and surround portions of the magnetic core within the pouch. Because of the use of a generally continuous loop magnetic core of high permeability, there is little or virtually no magnetic flux leakage. A solid circular core of a high permeability material may be used. In an alternate embodiment of the present invention the magnetic core can be divided into two separate portions, one implanted within the pouch and one implanted within the peritoneum adjacent the pouch so that the two core portions combine to form a generally continuous loop magnetic path, separated only by the intestinal wall of the pouch.
摘要翻译：通过植入至少部分在功能化的肠袋（或袋）（例如回肠袋）内的变压器来提供额外的体内功率。变压器包括植入袋内的连续环形磁芯。袋本身包括通道，允许二次布线围绕并通过磁芯延伸并穿过其中心开口而不进入提供体内电流的袋。提供初级绕组的线从身体外部通过造口延伸到袋中并且围绕袋内的磁芯的部分。由于使用高磁导率的通常连续的环形磁芯，因此几乎没有或几乎没有磁通泄漏。可以使用高磁导率材料的实心圆芯。在本发明的替代实施例中，磁芯可以分为两个分开的部分，一个植入在囊内，一个植入在邻近袋的腹膜内，使得两个核心部分组合形成大致连续的环路径，分离只能通过肠壁的肠壁。

2. 发明申请

US20060155159A1 Power system for a heart actuation device 有权
标题翻译：用于心脏驱动装置的电力系统
公开(公告)号：US20060155159A1
公开(公告)日：2006-07-13
申请号：US11298423
申请日：2005-12-08
申请人： David Melvin
发明人： David Melvin
IPC分类号： A61M1/12
CPC分类号： A61M1/122 , A61M1/1003 , A61M1/1008 , A61M1/1049 , A61M1/1055 , A61M1/1068 , A61M1/1086 , A61M1/12 , A61M1/127 , A61M2205/33 , A61M2205/3303
摘要： Actuator mechanisms on the heart are of several types. In preferred embodiments, they are generally simple, durable, mechanical assemblies and are driven by power delivered from a remote location, generally outside the chest, by a variety of mechanisms. The invention teaches physical mechanisms (1) for transfer of cyclic power from outside the chest to the region of the heart for that purpose, either as translational or rotary motion. Also taught are electromechanical converting mechanisms suitable for delivering power to those transfer devices. The embodiments described herein for either transmission of energy from a site of generation to a conduit (2, 10, 22), and of conduits that then deliver energy to heart actuators, have contours and interfaces designed to promote a favorable biologic response similar to the pseudosynovial capsules that surround artificial joints. Further, design features are chosen to avoid both non-vented gas-filled chambers and static collections of tissue fluid.
摘要翻译：心脏上的致动器机制有几种类型。在优选实施例中，它们通常是简单，耐用的机械组件，并且通过各种机构从通常在胸部外部的远程位置递送的动力驱动。本发明教导了用于为了目的将循环功率从胸部外部转移到心脏区域的物理机制（1），作为平移或旋转运动。还教导了适于将功率传递给那些传送装置的机电转换机构。本文描述的用于将能量从发生位点传输到导管（2,10,22）的导管和然后将能量传递给心脏致动器的导管具有设计成促进类似于围绕人造关节的假性动脉胶囊。此外，选择设计特征以避免非排气的充气室和组织液的静态收集。

3. 发明申请

US20060178551A1 Securement system for a heart actuation device 审中-公开
标题翻译：心脏致动装置的采购系统
公开(公告)号：US20060178551A1
公开(公告)日：2006-08-10
申请号：US11299197
申请日：2005-12-08
申请人： David Melvin
发明人： David Melvin
IPC分类号： A61N1/362
CPC分类号： A61M1/1068 , A61M1/1008 , A61M1/12
摘要： The invention consists of means (1, 64, 81) of securing a powered active cyclically deforming jacket (13) that surrounds the outer or epicardial surface (12) of at least one chamber of the natural heart, as well as auxiliary components. Internal components suspended from the jacket (13) by heart wall-penetrating cords complete a restraining harness over the entire 3-dimensional boundary of the chamber or chambers. The embodiments of the invention also teach means (1, 64, 81) that are suitable to achieve secure fixation with limited operative exposure such as would be available in minimally invasive approaches, and means (89, 90, 91) by which later cardiac operation such as coronary bypass can be facilitated despite presence of the heart actuation device.
摘要翻译：本发明包括固定围绕天然心脏的至少一个室的外部或外膜表面（12）的动力活动的循环变形护套（13）以及辅助部件的装置（1，64,81）。通过心壁穿透绳索从护套（13）悬挂的内部部件在腔室的整个三维边界上完成约束束带。本发明的实施例还教导了适合于以有限的手术暴露（例如在微创方法中可获得的）的安全固定的装置（1，64,81），以及随后的心脏手术（89,90,91）即使存在心脏致动装置，也可以促进冠状动脉旁路。

4. 发明申请

US20060187550A1 Deforming jacket for a heart actuation device 失效
标题翻译：用于心脏致动装置的变形夹克
公开(公告)号：US20060187550A1
公开(公告)日：2006-08-24
申请号：US11298428
申请日：2005-12-08
申请人： David Melvin
发明人： David Melvin
IPC分类号： G02B5/18
CPC分类号： A61F2/2481 , A61B17/0469 , A61B2017/00243 , A61F2/2445 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/12
摘要： The invention consists of a cushioned active cyclically deforming cushion or jacket (39) that surrounds the outer or epicardial surface of at least one chamber (2, 3, 4, 5) of the natural heart, including its base, configured so that internal components may be suspended from the jacket (39) by heart wall-penetrating cords to complete a restraining harness over the entire 3-dimensional boundary of the chamber or chambers. The cushion or jacket (39) provides protective and stabilizing openings (8, 9, 10) for atria and their inflow valves as well as for great vessels and their outflow valves. It is equipped with one or more actuator mechanisms (37, 38) that cyclically change shape at one or more sites, thus altering heart wall shape and chamber volume.
摘要翻译：本发明包括围绕自然心脏的至少一个腔室（2,3,4,5）的外表面或外膜表面的缓冲活动的周期性变形的衬垫或护套（39），其包括其底部，构造成使内部组件可以通过心壁穿透线从护套（39）悬挂以在腔室的整个三维边界上完成约束束带。垫子或护套（39）为心房及其流入阀以及大容器及其流出阀提供保护和稳定开口（8,9,10）。它配备有一个或多个致动器机构（37,38），其在一个或多个位置周期性地改变形状，从而改变心壁形状和腔体积。

5. 发明申请

US20060155160A1 Actuation mechanisms for a heart actuation device 失效
标题翻译：用于心脏致动装置的致动机构
公开(公告)号：US20060155160A1
公开(公告)日：2006-07-13
申请号：US11298430
申请日：2005-12-08
申请人： David Melvin , Geoffrey Nay
发明人： David Melvin , Geoffrey Nay
IPC分类号： A61M1/12
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/0401 , A61B2017/00243 , A61B2017/0443 , A61B2017/048 , A61M1/1008 , A61M1/1049 , A61M1/1055 , A61M1/1068 , A61M1/12 , A61M1/122
摘要： An actuation mechanism for assisting the operation of the natural heart has a varying shape for deforming the heart. In one embodiment, a plurality of links (6) articulates with respect to each other for varying the shape of the actuation mechanism. The plurality of links (6) is configured for being positioned proximate to an outer surface of the heart for deforming the heart by varying the shape of the actuation mechanism. In another embodiment, a jacket (51) for coupling with an outer surface of the heart has a tether (50) coupled to successive sections of the jacket. The tether (50) is operable to be translated with respect to the jacket sections to vary the shape of the jacket (51) for deforming the heart. In another embodiment, a plurality of concentric ring structures (81-84) are coupled together to move with respect to each other in a concentric fashion. A movement mechanism coupled to the rings (81-84) is operable to vary their positions with respect to each other to vary the overall shape for deforming the heart.
摘要翻译：用于辅助自然心脏的操作的致动机构具有变形以使心脏变形的形状。在一个实施例中，多个连杆（6）相对于彼此铰接以改变致动机构的形状。多个连杆（6）构造成用于靠近心脏的外表面定位，以通过改变致动机构的形状使心脏变形。在另一个实施例中，用于与心脏的外表面联接的护套（51）具有联接到护套的连续部分的系绳（50）。系绳（50）可操作以相对于护套部分平移以改变护套（51）的形状以使心脏变形。在另一个实施例中，多个同心环结构（81-84）联接在一起以同心的方式相对于彼此移动。耦合到环（81-84）的移动机构可操作以相对于彼此改变其位置，以改变用于使心脏变形的整体形状。

6. 发明申请

US20060009676A1 Protective sheath apparatus and method for use with a heart wall actuation system for the natural heart 失效
标题翻译：用于自然心脏的心壁致动系统的保护鞘装置和方法
公开(公告)号：US20060009676A1
公开(公告)日：2006-01-12
申请号：US11194281
申请日：2005-08-01
申请人： David Melvin
发明人： David Melvin
IPC分类号： A61F13/00
CPC分类号： A61M1/1068 , A61M1/1046 , A61M1/1056 , A61M1/12
摘要： An actuation system for assisting the operation of the natural heart includes a framework for interfacing with a natural heart and which is coupled with tissue of the heart. An actuator element is adapted to be coupled to the framework and is configured for extending along a portion of a heart wall exterior surface. The actuator element is operable for deforming the portion of the heart wall to effect a reduction in the volume of the heart. A protective sheath is configured to extend along the heart wall between the actuator element and the heart wall portion for protecting the heart wall portion from damage by the actuator element. The protective sheath is flexible and operable to transmit, to the heart wall portion, a force thereon by the actuator element for indenting the heart wall portion.
摘要翻译：用于辅助自然心脏的操作的致动系统包括用于与自然心脏接合并与心脏的组织结合的框架。致动器元件适于联接到框架并且构造成用于沿着心脏壁外表面的一部分延伸。致动器元件可操作用于使心脏壁的部分变形以实现心脏体积的减小。保护套构造成沿致动器元件和心壁部分之间的心壁延伸，用于保护心壁部分免受致动器元件的损伤。保护套是柔性的并且可操作地通过致动器元件向心壁部分传递其上的力以压缩心壁部分。

7. 发明申请

US20050250976A1 Heart wall actuation system for the natural heart with shape limiting elements 审中-公开
标题翻译：心墙致动系统为自然心脏与形状限制元素
公开(公告)号：US20050250976A1
公开(公告)日：2005-11-10
申请号：US11185452
申请日：2005-07-20
申请人： David Melvin , Brad Klosterman , Alan Melvin
发明人： David Melvin , Brad Klosterman , Alan Melvin
IPC分类号： A61F2/00 , A61M1/10 , A61N1/362
CPC分类号： A61F2/2481 , A61M1/1001 , A61M1/106 , A61M1/1068 , A61M1/12
摘要： An actuation system for assisting the operation of the natural heart includes an actuator element adapted to be positioned proximate a portion of a heart wall. The actuator element is operable for acting on the heart wall portion to effect a change in the shape of the heart. A shape-limiting element is configured for being positioned proximate a heart wall. The shape-limiting element is operable for flexing to assume a curvature no greater than a predetermined curvature when the heart wall is acted upon and maintaining that predetermined curvature to control the shape of the actuated heart.
摘要翻译：用于辅助自然心脏的操作的致动系统包括适于定位成靠近心壁的一部分的致动器元件。致动器元件可操作以作用在心脏壁部分上以实现心脏形状的改变。形状限制元件构造成用于定位在心壁附近。形状限制元件可操作用于当心壁作用并保持该预定曲率以控制致动心脏的形状时，弯曲成不大于预定曲率的曲率。

8. 发明申请

US20050049702A1 Article and method for coupling muscle 审中-公开
标题翻译：文章和方法联合肌肉
公开(公告)号：US20050049702A1
公开(公告)日：2005-03-03
申请号：US10832014
申请日：2004-04-26
申请人： David Melvin
发明人： David Melvin
IPC分类号： A61F2/08 , A61M1/10 , A61F2/02
CPC分类号： A61F2/08 , A61B17/0401 , A61B17/0482 , A61B17/06 , A61B17/0643 , A61B17/11 , A61B17/1146 , A61B17/122 , A61B17/1285 , A61B2017/0472 , A61M1/1003 , A61M1/1008 , A61M1/1037 , A61M1/1068 , A61M1/12 , A61M1/122 , A61M1/127
摘要： An insertion kit for positioning a plurality of filaments into muscle includes at least one holder that is configured for being attached to an end portion of the muscle. The holder is coupled with a guide, such as on a frame. The guide conforms the muscle to a desired shape. An inserter, used in conjunction with a plurality of needles, inserts a plurality of filaments into the muscle.
摘要翻译：用于将多根细丝定位到肌肉中的插入套件包括至少一个被配置为附接到肌肉的端部的保持器。保持器与引导件（例如框架）连接。指南使肌肉符合所需的形状。与多个针结合使用的插入器将多根细丝插入到肌肉中。

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