专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09029517B2 Chromatography media and method 有权
标题翻译：色谱介质和方法
公开(公告)号：US09029517B2
公开(公告)日：2015-05-12
申请号：US13191992
申请日：2011-07-27
申请人： David Yavorsky , John Amara , Joaquin Umana , William Cataldo , Mikhail Kozlov , Matthew Stone
发明人： David Yavorsky , John Amara , Joaquin Umana , William Cataldo , Mikhail Kozlov , Matthew Stone
IPC分类号： B01J20/28 , B01J47/12 , C07K1/18 , C07K1/20 , C07K1/22 , B01D15/32 , B01D15/36 , B01D15/38 , B01J20/285 , B01J20/287 , B01J20/32 , B01J39/26 , B01J41/20 , B01J47/00
CPC分类号： B01J39/26 , B01D15/327 , B01D15/361 , B01D15/362 , B01D15/363 , B01D15/3804 , B01J20/28023 , B01J20/28059 , B01J20/285 , B01J20/287 , B01J20/3244 , B01J41/20 , B01J47/014 , B01J47/127 , C07K1/18 , C07K16/00 , C12N7/00 , C12N7/02 , G01N2030/521 , Y10S502/52724 , Y10T428/2938 , Y10T428/2973
摘要： Adsorptive media for chromatography, particularly ion-exchange chromatography, derived from a shaped fiber. In certain embodiments, the functionalized shaped fiber presents a fibrillated or ridged structure which greatly increases the surface area of the fibers when compared to ordinary fibers. Also disclosed herein is a method to add surface pendant functional groups that provides cation-exchange or anion-exchange functionality to the high surface area fibers. This pendant functionality is useful for the ion-exchange chromatographic purification of biomolecules, such as monoclonal antibodies (mAbs).
摘要翻译：来自成形纤维的用于色谱的吸附介质，特别是离子交换层析。在某些实施方案中，与普通纤维相比，官能化成形纤维呈现原纤化或脊状结构，其大大增加了纤维的表面积。本文还公开了向高表面积纤维添加提供阳离子交换或阴离子交换官能团的表面侧基官能团的方法。这种侧链官能团可用于生物分子的离子交换色谱纯化，如单克隆抗体（mAb）。

2. 发明申请

US20120029176A1 Chromatography Media And Method 有权
标题翻译：色谱介质和方法
公开(公告)号：US20120029176A1
公开(公告)日：2012-02-02
申请号：US13191992
申请日：2011-07-27
申请人： David Yavorsky , John Amara , Joaquin Umana , William Cataldo , Mikhail Kozlov , Matthew Stone
发明人： David Yavorsky , John Amara , Joaquin Umana , William Cataldo , Mikhail Kozlov , Matthew Stone
IPC分类号： B01D15/08 , B01D15/10 , B01D15/36 , C07K1/20 , B01D15/32 , C07K1/22 , C07K1/18 , B01D15/04 , B01D15/38
CPC分类号： B01J39/26 , B01D15/327 , B01D15/361 , B01D15/362 , B01D15/363 , B01D15/3804 , B01J20/28023 , B01J20/28059 , B01J20/285 , B01J20/287 , B01J20/3244 , B01J41/20 , B01J47/014 , B01J47/127 , C07K1/18 , C07K16/00 , C12N7/00 , C12N7/02 , G01N2030/521 , Y10S502/52724 , Y10T428/2938 , Y10T428/2973
摘要： Adsorptive media for chromatography, particularly ion-exchange chromatography, derived from a shaped fiber. In certain embodiments, the functionalized shaped fiber presents a fibrillated or ridged structure which greatly increases the surface area of the fibers when compared to ordinary fibers. Also disclosed herein is a method to add surface pendant functional groups that provides cation-exchange or anion-exchange functionality to the high surface area fibers. This pendant functionality is useful for the ion-exchange chromatographic purification of biomolecules, such as monoclonal antibodies (mAbs).
摘要翻译：来自成形纤维的用于色谱的吸附介质，特别是离子交换层析。在某些实施方案中，与普通纤维相比，功能化成形纤维呈现原纤化或脊状结构，其大大增加了纤维的表面积。本文还公开了一种向高表面积纤维添加提供阳离子交换或阴离子交换官能团的表面侧基官能团的方法。这种侧链官能团可用于生物分子的离子交换色谱纯化，如单克隆抗体（mAb）。

3. 发明申请

US20070081921A1 Emissive polymers and devices incorporating these polymers 有权
标题翻译：发射聚合物和掺入这些聚合物的装置
公开(公告)号：US20070081921A1
公开(公告)日：2007-04-12
申请号：US11541028
申请日：2006-09-29
申请人： Timothy Swager , John Amara
发明人： Timothy Swager , John Amara
IPC分类号： G01N21/00
CPC分类号： C09K11/06 , C08G61/02 , C09K9/02 , C09K2211/1425 , Y10T436/14 , Y10T436/145555
摘要： The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics such as heterocycles, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer.
摘要翻译：本发明涉及一类具有发色团的发光和导电聚合物组合物，特别是这些组合物的固体膜显示增加的发光寿命，量子产率和放大的发射。这些期望的性质可以通过具有刚性基团的聚合物来提供，所述刚性基团被设计成在凝固时防止聚合物重组，聚集或π层叠。这些聚合物在溶剂和热暴露方面也能表现出非常高的稳定性。本发明还涉及通过这些聚合物的发光和导电性质来感测分析物的传感器和方法。可以通过在聚合物表面活化发色团来感测分析物。分析物包括芳族化合物如杂环，磷酸酯基团，特别是气体中的爆炸物和化学战剂。本发明还涉及通过引入具有能量迁移途径的聚合物和/或提供聚合物作为嵌段共聚物或作为多层来扩增发射的装置和方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式