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1. 发明授权

US08008617B1 Ion transfer device 有权
标题翻译：离子转移装置
公开(公告)号：US08008617B1
公开(公告)日：2011-08-30
申请号：US12344872
申请日：2008-12-29
申请人： John C. Berends, Jr. , Timothy P. Karpetsky , Ross C. Willoughby , Edward W. Sheehan
发明人： John C. Berends, Jr. , Timothy P. Karpetsky , Ross C. Willoughby , Edward W. Sheehan
IPC分类号： B01D59/44
CPC分类号： H01J49/0422
摘要： Ions carried in a flowing gas stream are transferred to another gas stream of different composition or purity through an ion selective aperture communicating between the gas streams. The ion selective aperture is formed of a central layer which has an electrically conductive layer on each of its surfaces. One or more open channels extend through the central layer and surface layers allowing physical movement of ions therethrough under the urging and influence of an electric field created by imposing a voltage differential between the conductive surface layers of the ion selective aperture. The gas flow rates of the different gas streams may be independently varied to allow adjustment of ion concentration and flow rate to meet the needs of the ion destination. This device can control sample ion introduction into gas-phase ion detectors, such as ion mobility analyzers, differential mobility analyzers, mass spectrometers, and combinations thereof.
摘要翻译：携带在流动气流中的离子通过在气流之间连通的离子选择孔转移到不同组成或纯度的另一种气流中。离子选择孔由中心层形成，在其每个表面上具有导电层。在通过在离子选择孔的导电表面层之间施加电压差而产生的电场的推动和影响下，一个或多个开放通道延伸穿过中心层和表面层，允许离子物理移动。可以独立地改变不同气流的气体流速，以允许调节离子浓度和流速以满足离子目的地的需要。该装置可以将样品离子引入气相离子检测器，例如离子迁移率分析仪，差速移动分析仪，质谱仪及其组合。

2. 发明授权

US07569812B1 Remote reagent ion generator 有权
标题翻译：远程试剂离子发生器
公开(公告)号：US07569812B1
公开(公告)日：2009-08-04
申请号：US11544252
申请日：2006-10-07
申请人： Timothy P. Karpetsky , John C. Berends, Jr. , Edward W. Sheehan , Ross C. Willoughby
发明人： Timothy P. Karpetsky , John C. Berends, Jr. , Edward W. Sheehan , Ross C. Willoughby
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J49/145 , H01J49/0468 , H01J49/067
摘要： An improved ion source and means for collecting and focusing dispersed gas-phase ions from a remote reagent chemical ionization source (R2CIS) at atmospheric or intermediate pressure is described. The R2CIS is under electronic control and can produce positive, negative, or positive and negative reagent ions simultaneously. This remote source of reagent ions is separated from a low-field sample ionization region by a stratified array of elements, each element populated with a plurality of openings, wherein DC potentials are applied to each element necessary for transferring reagent ions from the R2CIS into the low-field sample ionization region where the reagent ions react with neutral and/or ionic sample forming sample ionic species. The resulting sample ionic species are then introduced into a mass spectrometer, ion mobility spectrometer or other sensor capable of detecting the sample ions. Embodiments of this invention are methods and devices for improving sensitivity of mass spectrometry when gas and liquid chromatographic separation techniques are coupled to atmospheric and intermediate pressure photo-ionization, chemical ionization, and thermospray ionization sources; and improving the sensitivity of chemical detectors or probes.
摘要翻译：描述了改进的离子源和用于在大气压或中压下从远程试剂化学电离源（R2CIS）收集和聚焦分散的气相离子的装置。 R2CIS处于电子控制下，可以同时产生正，负或正，负反应离子。这种远程的试剂离子源通过分层阵列的元件与低场样品电离区域分开，每个元件填充有多个开口，其中DC电位被施加到将试剂离子从R2CIS转移到低场样品电离区域，其中试剂离子与形成样品离子物质的中性和/或离子样品反应。然后将所得样品离子物质引入质谱仪，离子迁移谱仪或能够检测样品离子的其他传感器。本发明的实施例是当气体和液相色谱分离技术耦合到大气和中压光电离，化学电离和热喷射电离源时提高质谱的灵敏度的方法和装置; 并提高化学检测器或探针的灵敏度。

3. 发明授权

US07576322B2 Non-contact detector system with plasma ion source 有权
标题翻译：具有等离子体离子源的非接触检测器系统
公开(公告)号：US07576322B2
公开(公告)日：2009-08-18
申请号：US11594401
申请日：2006-11-08
申请人： Timothy P. Karpetsky , John C. Berends, Jr.
发明人： Timothy P. Karpetsky , John C. Berends, Jr.
IPC分类号： H01J49/00 , H01J49/10 , B01D59/44
CPC分类号： H01J49/142 , H05H1/46 , H05H2001/466
摘要： A system for the non-contact detection of analyte chemicals, including explosives, chemical warfare agents and the like, employs a non-equilibrium plasma that is maintained at a temperature sufficiently low so as to avoid thermal damage to a surface, such as clothing or skin, that is being examined to thereby produce analyte ions and other charged particles. The ions are collected and passed into a sensor for detection and identification.
摘要翻译：用于非接触检测分析物的物质（包括爆炸物，化学战剂等）的系统采用保持在足够低的温度的非平衡等离子体，以避免对表面的热损伤，例如衣服或皮肤，正在被检查，从而产生分析离子和其他带电粒子。离子被收集并传递到传感器中进行检测和鉴定。

4. 发明授权

US08308339B2 Method and means for precision mixing 有权
公开(公告)号：US08308339B2
公开(公告)日：2012-11-13
申请号：US13363327
申请日：2012-01-31
申请人： Timothy P. Karpetsky , John C. Berends, Jr.
发明人： Timothy P. Karpetsky , John C. Berends, Jr.
IPC分类号： B01F5/04
CPC分类号： B01F3/022 , B01F3/0865 , B01F5/0473 , B01F15/0241 , B01F15/0246 , B01F2215/0037
摘要： An extremely dilute mixture of a liquid in a flowing fluid stream is prepared by forming tiny droplets of the liquid and injecting the droplets individually into the flowing stream. The rate at which liquid is added to the flowing stream is determined by the number of droplet forming units that are provided and upon the frequency with which the units are activated, allowing a precise digital control of the concentration of the liquid in the flowing fluid stream.

5. 发明授权

US08123396B1 Method and means for precision mixing 有权
标题翻译：精密混合的方法和方法
公开(公告)号：US08123396B1
公开(公告)日：2012-02-28
申请号：US12153358
申请日：2008-05-16
申请人： Timothy P. Karpetsky , John C. Berends, Jr.
发明人： Timothy P. Karpetsky , John C. Berends, Jr.
IPC分类号： B01F5/04
CPC分类号： B01F3/022 , B01F3/0865 , B01F5/0473 , B01F15/0241 , B01F15/0246 , B01F2215/0037
摘要： An extremely dilute mixture of a liquid in a flowing fluid stream is prepared by forming tiny droplets of the liquid and injecting the droplets individually into the flowing stream. The rate at which liquid is added to the flowing stream is determined by the number of droplet forming units that are provided and upon the frequency with which the units are activated, allowing a precise digital control of the concentration of the liquid in the flowing fluid stream.
摘要翻译：通过形成液体的微小液滴并将液滴分别注入流动流中来制备流动流体流中液体的极稀混合物。液体添加到流动流中的速率由提供的液滴形成单元的数量和单元被激活的频率确定，允许对流动流体流中的液体的浓度进行精确的数字控制。

6. 发明授权

US06272937B1 Gas sampling system 有权
标题翻译：气体采样系统
公开(公告)号：US06272937B1
公开(公告)日：2001-08-14
申请号：US09711522
申请日：2000-11-14
申请人： R. William Mengel , Thomas G. Albro , John C. Berends, Jr. , Robert S. Marshall , Christopher D. Sloop
发明人： R. William Mengel , Thomas G. Albro , John C. Berends, Jr. , Robert S. Marshall , Christopher D. Sloop
IPC分类号： G01N122
CPC分类号： G01N33/0011 , G01N1/2214 , G01N1/2273 , G01N1/24 , G01N1/405 , G01N2030/025 , G01N2030/128 , G01N2033/0019
摘要： A gas sampling system includes a sample trapping module having a gas pump and a power supply, and a removable magazine that fits within a port of the trapping module. The magazine contains a non-volatile electronic memory, which controls operation of the trapping module, and has a rotating carousel for holding sample tubes. Individual sample tubes are sealed at each end by a cap that has a needle-pierceable septum, and contain a solid collector material to trap chemical and biological contaminants in a gas sample drawn through the sample tube. Individual sample tubes are moved into and out of a sampling location by incremental rotation of the carousel and, while at the sampling location, a pair of hollow bore needles are inserted through the sample tube end caps to allow the drawing of a gas sample through the tube.
摘要翻译：气体采样系统包括具有气体泵和电源的样品捕集模块，以及装配在捕集模块的端口内的可移除的盒。该杂志包含一个非易失性电子存储器，用于控制捕获模块的操作，并具有用于保持样品管的旋转转盘。每个样品管在每一端通过具有可针刺的隔膜的盖密封，并且包含固体收集器材料以将化学和生物污染物捕获在通过样品管中抽取的气体样品中。通过圆盘传送带的增量旋转将单个样品管移入和取出采样位置，而在采样位置，一对中空孔针插入样品管端盖，以允许气体样品通过管。

7. 发明授权

US06244117B1 Means for trapping contaminants contained in a gas 有权
标题翻译：用于捕获包含在气体中的污染物的装置
公开(公告)号：US06244117B1
公开(公告)日：2001-06-12
申请号：US09711310
申请日：2000-11-14
申请人： R. William Mengel , Thomas G. Albro , John C. Berends, Jr. , Robert S. Marshall , Christopher D. Sloop
发明人： R. William Mengel , Thomas G. Albro , John C. Berends, Jr. , Robert S. Marshall , Christopher D. Sloop
IPC分类号： G01N122
CPC分类号： G01N33/0011 , G01N1/2214 , G01N1/2273 , G01N1/24 , G01N1/405 , G01N2030/025 , G01N2030/128 , G01N2033/0019
摘要： A gas sampling system includes a sample trapping module having a gas pump and a power supply, and a removable magazine that fits within a port of the trapping module. The magazine contains a non-volatile electronic memory, which controls operation of the trapping module, and has a rotating carousel for holding sample tubes. Individual sample tubes are sealed at each end by a cap that has a needle-pierceable septum, and contain a solid collector material to trap chemical and biological contaminants in a gas sample drawn through the sample tube. Individual sample tubes are moved into and out of a sampling location by incremental rotation of the carousel and, while at the sampling location, a pair of hollow bore needles are inserted through the sample tube end caps to allow the drawing of a gas sample through the tube.
摘要翻译：气体采样系统包括具有气体泵和电源的样品捕集模块，以及装配在捕集模块的端口内的可移除的盒。该杂志包含一个非易失性电子存储器，用于控制捕获模块的操作，并具有用于保持样品管的旋转转盘。每个样品管在每一端通过具有可针刺的隔膜的盖密封，并且包含固体收集器材料以将化学和生物污染物捕获在通过样品管中抽取的气体样品中。通过圆盘传送带的增量旋转将单个样品管移入和取出采样位置，而在采样位置，一对中空孔针插入样品管端盖，以允许气体样品通过管。

8. 发明授权

US07568401B1 Sample tube holder 有权
标题翻译：样品管架
公开(公告)号：US07568401B1
公开(公告)日：2009-08-04
申请号：US11455334
申请日：2006-06-19
申请人： John C. Berends, Jr.
发明人： John C. Berends, Jr.
IPC分类号： G01N1/00
CPC分类号： G01N1/2214 , G01N1/405 , G01N2030/128
摘要： A sorbent-filled sample tube is mounted to an aspirating source using a sample tube holder that includes a compression fitting having a fitting body, a cap, and a ferrule. The fitting cap is extended as a torque tube that surrounds the sample tube and has a length approximately equal to that of the sample tube to thereby protect the sample tube from damage. The free end of the torque tube is formed as a thumb wheel for ease in inserting and removing the sample tube without the use of a wrench or other tool.
摘要翻译：吸附剂填充的样品管使用样品管保持器安装到抽吸源，样品管保持器包括具有配合体，帽和套圈的压缩配件。装配帽作为扭矩管延伸，其围绕样品管并且具有与样品管的长度大致相等的长度，从而保护样品管免受损坏。扭矩管的自由端形成为拇指轮，以便于不使用扳手或其他工具插入和移除样品管。

9. 发明授权

US06321609B1 Magazine for use with a gas sampling system 有权
标题翻译：用于气体采样系统的杂志
公开(公告)号：US06321609B1
公开(公告)日：2001-11-27
申请号：US09711523
申请日：2000-11-14
申请人： R. William Mengel , Thomas G. Albro , John C. Berends, Jr. , Robert S. Marshall , Christopher D. Sloop
发明人： R. William Mengel , Thomas G. Albro , John C. Berends, Jr. , Robert S. Marshall , Christopher D. Sloop
IPC分类号： G01N122
CPC分类号： G01N33/0011 , G01N1/2214 , G01N1/2273 , G01N1/24 , G01N1/405 , G01N2030/025 , G01N2030/128 , G01N2033/0019
摘要： A gas sampling system includes a sample trapping module having a gas pump and a power supply, and a removable magazine that fits within a port of the trapping module. The magazine contains a non-volatile electronic memory, which controls operation of the trapping module, and has a rotating carousel for holding sample tubes. Individual sample tubes are sealed at each end by a cap that has a needle-pierceable septum, and contain a solid collector material to trap chemical and biological contaminants in a gas sample drawn through the sample tube. Individual sample tubes are moved into and out of a sampling location by incremental rotation of the carousel and, while at the sampling location, a pair of hollow bore needles are inserted through the sample tube end caps to allow the drawing of a gas sample through the tube.
摘要翻译：气体采样系统包括具有气体泵和电源的样品捕集模块，以及装配在捕集模块的端口内的可移除的盒。该杂志包含一个非易失性电子存储器，用于控制捕获模块的操作，并具有用于保持样品管的旋转转盘。每个样品管在每一端通过具有可针刺的隔膜的盖密封，并且包含固体收集器材料以将化学和生物污染物捕获在通过样品管中抽取的气体样品中。通过圆盘传送带的增量旋转将单个样品管移入和取出采样位置，而在采样位置，一对中空孔针插入样品管端盖，以允许气体样品通过管。

10. 发明授权

US07073403B2 Method and apparatus for the collection of samples 有权
标题翻译：收集样品的方法和装置
公开(公告)号：US07073403B2
公开(公告)日：2006-07-11
申请号：US10988915
申请日：2004-11-15
申请人： Thomas G. Albro , John C. Berends, Jr.
发明人： Thomas G. Albro , John C. Berends, Jr.
IPC分类号： G01N1/14
CPC分类号： G08B21/14
摘要： A system for the collection of near real time confirmation samples is provided to quickly eliminate false positive alarms by confirming the presence or absence of a chemical agent when a monitor operating in near real time to detect the presence of that chemical agent generates an alarm. The confirmation sampling system is synchronized with the near real time monitor and the confirmation sampler and monitor draw common samples of the atmosphere of concern. In the event that the monitor generates an alarm, the confirmation sampler preserves the sample taken contemporaneously with the alarm event for separate analysis, and also takes and preserves one or more follow-on samples.
摘要翻译：提供用于收集近实时确认样品的系统，以便在近乎实时操作的监视器检测到该化学试剂的存在产生报警时，通过确认化学试剂的存在或不存在来快速消除假阳性报警。确认采样系统与近实时监控器同步，确认采样器和监视器绘制所关注的气氛的常见样品。如果监视器产生警报，则确认采样器会保留与报警事件同时采集的样本以进行单独分析，并且还将保留一个或多个后续样本。

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