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1. 发明授权

US08765739B2 Azetidine compound and pharmaceutical use thereof 有权
标题翻译：氮杂环丁烷化合物及其药物用途
公开(公告)号：US08765739B2
公开(公告)日：2014-07-01
申请号：US12780146
申请日：2010-05-14
申请人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
发明人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
IPC分类号： A61K31/496 , A61K31/4427 , A61K31/4439 , A61K31/5377 , A61K31/551 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
CPC分类号： C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： Compounds of formula [I]: wherein each symbol is as defined in the description, or a pharmaceutically acceptable salts or solvates thereof.
摘要翻译：式[I]化合物：其中每个符号如说明书中所定义，或其药学上可接受的盐或溶剂化物。

2. 发明申请

US20100331301A1 AZETIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF 有权
标题翻译： AZETIDINE化合物及其药物用途
公开(公告)号：US20100331301A1
公开(公告)日：2010-12-30
申请号：US12780146
申请日：2010-05-14
申请人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
发明人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
IPC分类号： A61K31/4427 , C07D401/06 , C07D401/14 , C07D413/14 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61K31/4545 , A61K31/553 , A61K31/551 , A61P37/00 , A61P29/00 , A61P19/10 , A61P35/00 , A61P19/08 , A61P19/02 , A61P17/06 , A61P1/00
CPC分类号： C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： Compounds of formula [I]: wherein each symbol is as defined in the description, or a pharmaceutically acceptable salts or solvates thereof.
摘要翻译：式[I]化合物：其中每个符号如说明书中所定义，或其药学上可接受的盐或溶剂化物。

3. 发明申请

US20060135572A1 CaSR antagonist 失效
标题翻译： CaSR拮抗剂
公开(公告)号：US20060135572A1
公开(公告)日：2006-06-22
申请号：US11286378
申请日：2005-11-25
申请人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
发明人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
IPC分类号： A61K31/426 , A61K31/381 , A61K31/138 , C07D333/22 , C07D277/22
CPC分类号： C07D257/04 , C07C217/28 , C07C311/51 , C07D277/56 , C07D285/08 , C07D333/38 , C07F9/3834 , C07F9/4021
摘要： The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis. A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the description.
摘要翻译：本发明提供具有钙敏感受体拮抗作用的化合物，含有该化合物，特别是钙受体拮抗剂的药物组合物和用于骨质疏松症的治疗药物。由下式（1）表示的化合物，其药学上可接受的盐或其光学活性形式：其中每个符号如说明书中所定义。

4. 发明授权

US07285572B2 CaSR antagonist 失效
标题翻译： CaSR拮抗剂
公开(公告)号：US07285572B2
公开(公告)日：2007-10-23
申请号：US11286378
申请日：2005-11-25
申请人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
发明人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
IPC分类号： A61K31/19 , A61K31/195 , A61K31/185 , C07C61/00 , C07C211/00
CPC分类号： C07D257/04 , C07C217/28 , C07C311/51 , C07D277/56 , C07D285/08 , C07D333/38 , C07F9/3834 , C07F9/4021
摘要： The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis. A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the description.
摘要翻译：本发明提供具有钙敏感受体拮抗作用的化合物，含有该化合物，特别是钙受体拮抗剂的药物组合物和用于骨质疏松症的治疗药物。由下式（1）表示的化合物，其药学上可接受的盐或其光学活性形式：其中每个符号如说明书中所定义。

5. 发明申请

US20050032796A1 CaSR antagonist 有权
标题翻译： CaSR拮抗剂
公开(公告)号：US20050032796A1
公开(公告)日：2005-02-10
申请号：US10830480
申请日：2004-04-23
申请人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
发明人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
IPC分类号： A61P3/14 , A61P19/02 , A61P19/08 , A61P19/10 , A61P29/00 , A61P43/00 , C07C217/28 , C07C317/44 , C07C323/62 , C07D215/12 , C07D295/155 , C07D307/79 , A61K31/5377 , A61K31/4025 , A61K31/4439 , A61K31/454 , A61K31/4545 , C07D413/14 , C07D43/14
CPC分类号： C07D213/80 , C07C217/28 , C07C317/44 , C07C323/62 , C07C2601/02 , C07D215/12 , C07D295/155 , C07D307/79
摘要： A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the specification. A compound having a calcium-sensing receptor antagonistic action, a pharmaceutical composition comprising the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis are provided.
摘要翻译：由下式（1）表示的化合物，其药学上可接受的盐或其光学活性形式：其中每个符号如说明书中所定义。提供了具有钙敏感受体拮抗作用的化合物，包含该化合物，特别是钙受体拮抗剂和用于骨质疏松症的治疗药物的药物组合物。

6. 发明申请

US20120301552A1 CaSR Antagonist 审中-公开
标题翻译： CaSR拮抗剂
公开(公告)号：US20120301552A1
公开(公告)日：2012-11-29
申请号：US13336205
申请日：2011-12-23
申请人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
发明人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
IPC分类号： A61K31/195 , A61K31/24 , C07D213/80 , A61K31/4418 , C07D307/79 , A61K31/353 , C07D295/155 , A61K31/5377 , A61P19/10 , A61K38/29 , A61K38/23 , A61K33/42 , C07C229/38 , A61K31/343
CPC分类号： C07D213/80 , C07C217/28 , C07C317/44 , C07C323/62 , C07C2601/02 , C07D215/12 , C07D295/155 , C07D307/79
摘要： A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the specification. A compound having a calcium-sensing receptor antagonistic action, a pharmaceutical composition comprising the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis are provided.
摘要翻译：由下式（1）表示的化合物，其药学上可接受的盐或其光学活性形式：其中每个符号如说明书中所定义。提供了具有钙敏感受体拮抗作用的化合物，包含该化合物，特别是钙受体拮抗剂和用于骨质疏松症的治疗药物的药物组合物。

7. 发明申请

US20080255042A1 CaSR Antagonist 审中-公开
标题翻译： CaSR拮抗剂
公开(公告)号：US20080255042A1
公开(公告)日：2008-10-16
申请号：US11840739
申请日：2007-08-17
申请人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
发明人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
IPC分类号： A61K38/16 , C07C63/06 , A61K31/195 , A61K31/662 , A61P19/10 , A61K31/352 , A61K31/56 , A61K31/592
CPC分类号： C07D213/80 , C07C217/28 , C07C317/44 , C07C323/62 , C07C2601/02 , C07D215/12 , C07D295/155 , C07D307/79
摘要： A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the specification. A compound having a calcium-sensing receptor antagonistic action, a pharmaceutical composition comprising the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis are provided.
摘要翻译：由下式（1）表示的化合物，其药学上可接受的盐或其光学活性形式：其中每个符号如说明书中所定义。提供了具有钙敏感受体拮抗作用的化合物，包含该化合物，特别是钙受体拮抗剂和用于骨质疏松症的治疗药物的药物组合物。

8. 发明授权

US07304174B2 CaSR antagonist 有权
标题翻译： CaSR拮抗剂
公开(公告)号：US07304174B2
公开(公告)日：2007-12-04
申请号：US10830480
申请日：2004-04-23
申请人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
发明人： Yuko Shinagawa , Teruhiko Inoue , Toshihiro Kiguchi , Taku Ikenogami , Naoki Ogawa , Kenji Fukuda , Takashi Nakagawa , Masanori Shindo , Yuki Soejima
IPC分类号： C07C560/102 , C07C562/469
CPC分类号： C07D213/80 , C07C217/28 , C07C317/44 , C07C323/62 , C07C2601/02 , C07D215/12 , C07D295/155 , C07D307/79
摘要： A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the specification. A compound having a calcium-sensing receptor antagonistic action, a pharmaceutical composition comprising the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis are provided.
摘要翻译：由下式（1）表示的化合物，其药学上可接受的盐或其光学活性形式：

9. 发明授权

US08899584B2 Sheet reversing device 有权
标题翻译：换页装置
公开(公告)号：US08899584B2
公开(公告)日：2014-12-02
申请号：US13869907
申请日：2013-04-24
申请人： Hayato Kondo , Naoki Ogawa
发明人： Hayato Kondo , Naoki Ogawa
IPC分类号： B65H29/54 , B41F21/10 , B41J3/60 , B65H85/00 , B41J13/22
CPC分类号： B65H85/00 , B41F21/102 , B41F21/104 , B41F21/108 , B41J3/60 , B41J13/223
摘要： A sheet reversing device including a first conveyance unit, second conveyance unit, third conveyance unit, and sheet pressing member. The first conveyance unit includes a first holder, and a support surface that supports the sheet, and conveys the sheet with an edge held by the first holder, and its entire surface supported by the support surface. The second conveyance unit includes second holders, which convey the sheet. The third conveyance unit is supported to be swingable between a reception position at which the third conveyance unit receives the sheet, and a transfer position at which the third conveyance unit transfers the sheet to the second conveyance unit. The third conveyance unit includes a third holder, and conveys the sheet held by the third holder. The sheet pressing member presses the sheet, transferred from the third conveyance unit to the first conveyance unit, against the first conveyance unit support surface.
摘要翻译：一种纸张倒转装置，包括第一输送单元，第二输送单元，第三输送单元和纸张按压构件。第一传送单元包括第一保持器和支撑该片材的支撑表面，并且传送具有由第一保持器保持的边缘的片材以及由支撑表面支撑的整个表面。第二传送单元包括传送片材的第二保持器。第三输送单元被支撑在第三输送单元接收纸张的接收位置与第三输送单元将纸张转印到第二输送单元的转印位置之间摆动。第三传送单元包括第三保持器，并且传送由第三保持器保持的片。片材按压部件将从第三输送单元传送到第一输送单元的片材压靠在第一输送单元支撑面上。

10. 发明申请

US20130276652A1 SHEET PROCESSING APPARATUS 有权
标题翻译：板材加工设备
公开(公告)号：US20130276652A1
公开(公告)日：2013-10-24
申请号：US13868996
申请日：2013-04-23
申请人： Satoshi Murakami , Takanobu Aoki , Shinya Matsuyama , Hayato Kondo , Naoki Ogawa , Mikio Kamata , Soju Watanabe , Yasuhiro Suzuki
发明人： Satoshi Murakami , Takanobu Aoki , Shinya Matsuyama , Hayato Kondo , Naoki Ogawa , Mikio Kamata , Soju Watanabe , Yasuhiro Suzuki
IPC分类号： B41F21/10
CPC分类号： B41F21/104 , B41F21/102 , B41F21/108 , B41J3/60 , B41J13/223
摘要： This invention discloses a sheet processing apparatus including a sheet supply device, a first cylinder which includes at least one gripper device, a processing device, a sheet discharge device, and conveyance devices. The conveyance devices include a plurality of gripper devices including at least one reversing gripper device. The conveyance devices also include a second cylinder and reversing swing arm shaft pregripper. The second cylinder grips and conveys one edge of the sheet by one gripper device of the plurality of gripper devices. The reversing swing arm shaft pregripper is supported to be swingable between the first cylinder and the second cylinder, receives by the reversing gripper device the other edge of the sheet conveyed by the second cylinder, and transfers the received other edge of the sheet to the gripper device of the first cylinder by a gripping change.
摘要翻译：本发明公开了一种片材处理装置，其包括片材供应装置，包括至少一个夹持装置的第一筒体，处理装置，片材排出装置和输送装置。输送装置包括多个夹持装置，其包括至少一个反向夹持装置。输送装置还包括第二气缸和反向摆臂预握器。第二气缸通过多个夹持装置的一个夹持装置夹持并输送片材的一个边缘。反转摆臂轴预抓爪被支撑在第一气缸和第二气缸之间可摆动，由反向夹持装置接收由第二气缸传送的薄片的另一边缘，并将所接收的片材的另一边缘传送到夹具第一个气缸的装置通过夹紧变化。

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