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1. 发明授权

US08765739B2 Azetidine compound and pharmaceutical use thereof 有权
标题翻译：氮杂环丁烷化合物及其药物用途
公开(公告)号：US08765739B2
公开(公告)日：2014-07-01
申请号：US12780146
申请日：2010-05-14
申请人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
发明人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
IPC分类号： A61K31/496 , A61K31/4427 , A61K31/4439 , A61K31/5377 , A61K31/551 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
CPC分类号： C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： Compounds of formula [I]: wherein each symbol is as defined in the description, or a pharmaceutically acceptable salts or solvates thereof.
摘要翻译：式[I]化合物：其中每个符号如说明书中所定义，或其药学上可接受的盐或溶剂化物。

2. 发明申请

US20100331301A1 AZETIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF 有权
标题翻译： AZETIDINE化合物及其药物用途
公开(公告)号：US20100331301A1
公开(公告)日：2010-12-30
申请号：US12780146
申请日：2010-05-14
申请人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
发明人： Kazutaka Ikegashira , Taku Ikenogami , Naoki Ogawa , Tatsuya Matsumoto , Takahiro Oka , Takuya Matsuo , Takayuki Yamasaki
IPC分类号： A61K31/4427 , C07D401/06 , C07D401/14 , C07D413/14 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61K31/4545 , A61K31/553 , A61K31/551 , A61P37/00 , A61P29/00 , A61P19/10 , A61P35/00 , A61P19/08 , A61P19/02 , A61P17/06 , A61P1/00
CPC分类号： C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： Compounds of formula [I]: wherein each symbol is as defined in the description, or a pharmaceutically acceptable salts or solvates thereof.
摘要翻译：式[I]化合物：其中每个符号如说明书中所定义，或其药学上可接受的盐或溶剂化物。

3. 发明授权

US08008292B2 Condensed benzamide compounds and inhibitors of vanilloid receptor subtype 1 (VR1) activity 有权
标题翻译：浓缩的苯甲酰胺化合物和香草素受体亚型1（VR1）活性的抑制剂
公开(公告)号：US08008292B2
公开(公告)日：2011-08-30
申请号：US11183265
申请日：2005-07-15
申请人： Yoshihisa Koga , Shinji Yata , Takashi Watanabe , Takuya Matsuo , Takayuki Yamasaki , Masahiro Sakata , Wataru Kondo , Hidekazu Ozeki , Yoshikazu Hori
发明人： Yoshihisa Koga , Shinji Yata , Takashi Watanabe , Takuya Matsuo , Takayuki Yamasaki , Masahiro Sakata , Wataru Kondo , Hidekazu Ozeki , Yoshikazu Hori
IPC分类号： A61K31/535 , C07D265/36 , C07D498/02
CPC分类号： A61K45/06 , C07D401/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： To provide a compound having an excellent inhibitory effect on vanilloid receptor subtype 1 (VR1) activity which is effective in treating diseases to which the vanilloid receptor subtype 1 (VR1) activity is involved, such as pain, acute pain, chronic pain, neuropathic pain, rheumatoid arthritis pain, neuralgia, etc. and a pharmaceutical composition containing the compound. The object has been attained by a condensed benzamide compound represented by the following formula (the symbols in the formula have the same meanings defined in the specification) or its salt:
摘要翻译：为了提供对于涉及涉及香草素受体亚型1（VR1）活性的疾病（例如疼痛，急性疼痛，慢性疼痛，神经性疼痛）有效治疗对香草素受体亚型1（VR1）活性具有优异抑制作用的化合物，类风湿性关节炎疼痛，神经痛等，以及含有该化合物的药物组合物。本发明的目的是通过下述式（式中的符号与说明书中所定义的相同含义）或其盐进行缩合的苯甲酰胺化合物来实现：

4. 发明申请

US20060035882A1 CONDENSED BENZAMIDE COMPOUNDS AND INHIBITORS OF VANILLOID RECEPTOR SUBTYPE 1 (VR1) ACTIVITY 有权
标题翻译：甘氨酸受体亚型1（VR1）活性的简并的苄基化合物和抑制剂
公开(公告)号：US20060035882A1
公开(公告)日：2006-02-16
申请号：US11183265
申请日：2005-07-15
申请人： Yoshihisa Koga , Shinji Yata , Takashi Watanabe , Takuya Matsuo , Takayuki Yamasaki , Masahiro Sakata , Wataru Kondo , Hidekazu Ozeki , Yoshikazu Hori
发明人： Yoshihisa Koga , Shinji Yata , Takashi Watanabe , Takuya Matsuo , Takayuki Yamasaki , Masahiro Sakata , Wataru Kondo , Hidekazu Ozeki , Yoshikazu Hori
IPC分类号： A61K31/5513 , A61K31/553 , A61K31/554
CPC分类号： A61K45/06 , C07D401/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： To provide a compound having an excellent inhibitory effect on vanilloid receptor subtype 1 (VR1) activity which is effective in treating diseases to which the vanilloid receptor subtype 1 (VR1) activity is involved, such as pain, acute pain, chronic pain, neuropathic pain, rheumatoid arthritis pain, neuralgia, etc. and a pharmaceutical composition containing the compound. The object has been attained by a condensed benzamide compound represented by the following formula (the symbols in the formula have the same meanings defined in the specification) or its salt:
摘要翻译：为了提供对于涉及涉及香草素受体亚型1（VR1）活性的疾病（例如疼痛，急性疼痛，慢性疼痛，神经性疼痛）有效治疗对香草素受体亚型1（VR1）活性具有优异抑制作用的化合物，类风湿性关节炎疼痛，神经痛等，以及含有该化合物的药物组合物。本发明的目的是通过下述式（式中的符号与说明书中所定义的相同含义）或其盐进行缩合的苯甲酰胺化合物来实现：

5. 发明授权

US09209469B2 Solid oxide fuel cell device 有权
标题翻译：固体氧化物燃料电池装置
公开(公告)号：US09209469B2
公开(公告)日：2015-12-08
申请号：US13823902
申请日：2011-09-28
申请人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
发明人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
IPC分类号： H01M8/06 , H01M8/04 , C01B3/02 , H01M8/24 , H01M8/12
CPC分类号： H01M8/0618 , C01B3/02 , H01M8/0271 , H01M8/04022 , H01M8/04052 , H01M8/04223 , H01M8/04225 , H01M8/04268 , H01M8/0432 , H01M8/04373 , H01M8/04776 , H01M8/0662 , H01M8/0668 , H01M8/2428 , H01M8/243 , H01M8/2475 , H01M8/2484 , H01M2008/1293 , Y02E60/50 , Y02E60/525
摘要： To provide a solid oxide fuel cell device for preventing excess temperature rises inside a fuel cell module during the startup process. During a startup process, a control unit controls the supplied amounts of fuel gas, oxidant gas, and steam supplied to a reformer based on cell stack temperature and reformer temperature and causes transition to a generating process after transitioning to a POX process, an ATR process, and a SR process, and controls to cause a transition to the next process if in each process the cell stack temperature and reformer temperature meet transition conditions set for each; when control unit determines a temperature rise assist state, it controls to cause a transition to the generating process in a state of reduced fuel gas supply amounts compared to when it does not determine a temperature rise assist state.
摘要翻译：提供一种用于在启动过程中防止燃料电池模块内的过度温度升高的固体氧化物燃料电池装置。在启动过程中，控制单元基于电池堆温度和重整器温度来控制提供给重整器的燃料气体，氧化剂气体和蒸汽的供应量，并且在转换到POX过程之后引起向生成过程的转变，ATR过程和SR过程，并且如果在每个过程中，电池堆温度和重整器温度满足为每个过程设定的转变条件，则控制引起向下一个过程的转变; 当控制单元确定升温辅助状态时，与在不确定升温辅助状态的情况相比，在控制单元确定升温辅助状态的情况下，控制使燃料气体供给量减少的状态转变为发生过程。

6. 发明申请

US20140242488A1 SOLID OXIDE FUEL CELL SYSTEM 审中-公开
标题翻译：固体氧化物燃料电池系统
公开(公告)号：US20140242488A1
公开(公告)日：2014-08-28
申请号：US14347977
申请日：2011-09-29
申请人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
发明人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
IPC分类号： H01M8/04
CPC分类号： H01M8/04574 , H01M8/0432 , H01M8/04544 , H01M8/04604 , H01M8/04753 , H01M8/04895 , H01M8/0491 , H01M2008/1293
摘要： The present invention is a solid oxide fuel cell system for generating variable power in response to power demand, having: a fuel cell module; a fuel supply device; a power demand detection device; a controller for controlling the amount of fuel supplied by the fuel supply device based on the power demand, and for setting an extractable current value, being the maximum extractable current value; an inverter for extracting current from the fuel cell module within a range not exceeding the extractable current value; and an extractable current detection device for detecting actual extracted current extracted from the fuel cell module; whereby if certain increase-limiting condition is matched, then even when power demand is rising, the controller maintains the extractable current value at a certain value, or lowers the extractable current value, and does not increase that extractable current value.
摘要翻译：本发明是一种固体氧化物燃料电池系统，用于响应功率需求产生可变功率，具有：燃料电池模块; 燃料供应装置; 电力需求检测装置; 控制器，用于基于功率需求来控制由燃料供应装置供应的燃料量，并且设置作为最大可提取电流值的可提取电流值; 用于在不超过所述可提取电流值的范围内从所述燃料电池模块提取电流的逆变器; 以及可提取电流检测装置，用于检测从燃料电池模块提取的实际提取电流; 由此，如果某个限制条件匹配，则即使在功率需求上升的情况下，控制器将可提取电流值保持在一定值，或者降低可提取电流值，也不增加可提取电流值。

7. 发明申请

US20140234738A1 SOLID OXIDE FUEL CELL SYSTEM 有权
标题翻译：固体氧化物燃料电池系统
公开(公告)号：US20140234738A1
公开(公告)日：2014-08-21
申请号：US14347990
申请日：2011-09-29
申请人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
发明人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
IPC分类号： H01M8/04
CPC分类号： H01M8/04992 , H01M8/04626 , H01M8/04753 , H01M8/0491 , H01M8/243 , H01M8/2465 , Y02E60/50
摘要： The invention is a solid oxide fuel cell system including: a fuel cell module, a fuel flow regulator unit, a first power demand detection device, a control section for controlling a fuel supply amount and setting the current value extractable from the fuel cell module, an inverter for extracting current in a range not exceeding the extractable current value, and a power state detecting sensor for detecting actual extracted current value; whereby if actual extracted current value declines, then under circumstances where power demand begins to rise in a state of extra margin in the fuel supply amount after the controller suddenly decreases the extractable current value and suddenly reduces the electrical collector, the controller increases the extractable current value at a high current rise rate of change.
摘要翻译：本发明是一种固体氧化物燃料电池系统，包括：燃料电池模块，燃料流量调节单元，第一电力需求检测装置，用于控制燃料供应量并设定从燃料电池模块可提取的电流值的控制部分，用于在不超过所述可提取电流值的范围内提取电流的逆变器，以及用于检测实际提取的电流值的电力状态检测传感器; 如果实际提取的电流值下降，则在控制器突然降低可提取电流值并突然减少集电器之后，在燃料供给量的额外余量状态下电力需求开始上升的情况下，控制器增加可提取电流价值在高电流上升率变化。

8. 发明申请

US20110217603A1 SOLID OXIDE FUEL CELL 有权
标题翻译：固体氧化物燃料电池
公开(公告)号：US20110217603A1
公开(公告)日：2011-09-08
申请号：US13040884
申请日：2011-03-04
申请人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
发明人： Toshiharu Otsuka , Katsuhisa Tsuchiya , Tsukasa Shigezumi , Toshiharu Ooe , Kiyotaka Nakano , Takuya Matsuo
IPC分类号： H01M8/06
CPC分类号： H01M8/04776 , H01M8/04425 , H01M8/0612 , H01M8/0618 , H01M8/2428 , H01M8/243 , H01M2008/1293
摘要： To provide a solid oxide fuel cell in which the reformer is compact but is capable of supplying an appropriate quantity of fuel. The present invention is a solid oxide fuel cell (1) for generating electricity using fuel reformed by a reformer (20) and air, including a fuel supply means (38), a reformed air supply means (44), a water supply means (28) for supplying water to the reformer, a fuel supply quantity detection sensor (132) for detecting the quantity of fuel actually supplied, a fuel cell module (2), and a control means (110) for controlling each supply means so that the target quantities of fuel, reforming air, and water are fed into the reformer; the control means controls the fuel supply means to match the target fuel supply quantity, and controls the fuel supply means so that tracking performance of fuel supply quantity relative to target fuel supply quantity is higher when reforming air is being supplied to the reformer than when it is not being supplied.
摘要翻译：提供固体氧化物燃料电池，其中重整器紧凑但能够供应适量的燃料。本发明是一种使用由重整器（20）重整的燃料和空气发电的固体氧化物型燃料电池（1），包括燃料供给装置（38），改质空气供给装置（44），供水装置 28），用于向重整器供水的燃料供给量检测传感器（132），用于检测实际供给的燃料量的燃料供给量检测传感器（132），燃料电池模块（2）和控制装置（110），用于控制每个供给装置，将目标量的燃料，重整空气和水进料到重整器中; 控制装置控制燃料供给装置以匹配目标燃料供应量，并且控制燃料供应装置，使得当向重整器供应重整空气时，相对于目标燃料供应量的燃料供应量的跟踪性能比在没有提供。

9. 发明申请

US20070045730A1 Semiconductor device, method of manufacturing the same, and electronic device having the same 有权
标题翻译：半导体装置及其制造方法以及具有该半导体装置的电子装置
公开(公告)号：US20070045730A1
公开(公告)日：2007-03-01
申请号：US11542217
申请日：2006-10-04
申请人： Takeshi Noda , Hidehito Kitakado , Takuya Matsuo
发明人： Takeshi Noda , Hidehito Kitakado , Takuya Matsuo
IPC分类号： H01L29/76
CPC分类号： H01L29/66757 , H01L29/42384 , H01L29/78603 , H01L29/78621 , H01L29/78675
摘要： A semiconductor device, which can improve the effect of a hydrogenation treatment in case of using a GOLD structure, and a method of manufacturing thereof is provided. A gate insulating film is formed on a semiconductor layer, and a source region, a drain region, and LDD regions are formed in the semiconductor layer. A main gate is formed on the gate insulating film. A sub-gate is formed on the main gate and the gate insulating film so as to cover a part of the main gate and either the LDD regions adjacent to the source region or the drain region. An interlayer insulating film containing hydrogen is formed on the sub-gate, main gate, and gate insulating film. Subsequently, a heat treatment for hydrogenation is performed to terminate a crystal defect of the semiconductor layer with hydrogen.
摘要翻译：提供了可以提高在使用GOLD结构的情况下氢化处理的效果的半导体器件及其制造方法。在半导体层上形成栅极绝缘膜，在半导体层中形成源极区，漏极区，LDD区。在栅极绝缘膜上形成主栅极。在主栅极和栅极绝缘膜上形成子栅极，以覆盖主栅极的一部分和与源极区域或漏极区域相邻的LDD区域。在子栅极，主栅极和栅极绝缘膜上形成含有氢的层间绝缘膜。随后，进行用于氢化的热处理，以氢终止半导体层的晶体缺陷。

10. 发明申请

US20060035939A1 3-Aminobenzamide compounds and inhibitors of vanilloid receptor subtype 1 (VR1) activity 审中-公开
标题翻译： 3-氨基苯甲酰胺化合物和香草素受体亚型1（VR1）活性抑制剂
公开(公告)号：US20060035939A1
公开(公告)日：2006-02-16
申请号：US11181235
申请日：2005-07-14
申请人： Yoshihisa Koga , Shinji Yata , Takashi Watanabe , Takuya Matsuo , Masahiro Sakata , Wataru Kondo
发明人： Yoshihisa Koga , Shinji Yata , Takashi Watanabe , Takuya Matsuo , Masahiro Sakata , Wataru Kondo
IPC分类号： A61K31/455 , A61K31/165
CPC分类号： C07C237/40 , C07D213/74 , C07D213/82 , C07D401/12 , C07D413/04
摘要： The present invention relates to a novel 3-aminobenzamide compound represented by the following formula which effectively inhibits vanilloid receptor subtype 1 (VR1) activity (wherein, for example, R1 is a C1-6 alkyl group which may be substituted, R2 is a hydrogen atom, a C1-6 alkyl group or a C1-6 alkoxy group which may be substituted, R3 is a hydrogen atom or a C1-6 alkyl group, R4 is a C1-6 alkyl group, a C1-6 alkoxy group, or a halo C1-6 alkyl group, m is an integer of 1 to 5 and P is a carbon or hetero ring) or a pharmaceutically acceptable salt thereof. The pharmaceutical composition comprising as active ingredients the 3-aminobenzamide compound or a pharmaceutically acceptable salt thereof is useful for treating diseases involved in VR1 activity such as pain, acute pain, chronic pain, neuropathic pain, rheumatoid arthritis pain, and neuralgia.
摘要翻译：本发明涉及有效抑制香草素受体亚型1（VR1）活性的下式所示的新型3-氨基苯甲酰胺化合物（其中，例如R 1是C 1-6烷基，可以被取代，R 2是氢原子，可以被取代的C 1-6烷基或C 1-6烷氧基，R 3是氢原子或 C 1-6烷基，R 4是C 1-6烷基，C 1-6烷氧基或卤代C 1-6烷基，m是1〜5的整数，P 是碳或杂环）或其药学上可接受的盐。包含3-氨基苯甲酰胺化合物或其可药用盐作为活性成分的药物组合物可用于治疗涉及VR1活性的疾病，例如疼痛，急性疼痛，慢性疼痛，神经性疼痛，类风湿性关节炎疼痛和神经痛。

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