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1. 发明申请

US20130236124A1 IMAGE PROCESSING APPARATUS 有权
标题翻译：图像处理设备
公开(公告)号：US20130236124A1
公开(公告)日：2013-09-12
申请号：US13988770
申请日：2011-11-22
申请人： Rafael Wiemker , Thomas Buelow , Martin Bergtholdt , Kirsten Meetz , Ingwer-Curt Carlsen
发明人： Rafael Wiemker , Thomas Buelow , Martin Bergtholdt , Kirsten Meetz , Ingwer-Curt Carlsen
IPC分类号： G06T11/60
CPC分类号： G06T11/60 , G06T11/00
摘要： Image processing apparatus (100) for creating an overlaid presentation of a first input image (101) and a second input image (102) in an output image (108), the first input image comprising input values, the output image comprising vectors of output values, the vectors of output values representing colors of the output image, and the apparatus comprising an input (110) for obtaining the first input put image and the second input image, a rendering unit (140) configured for rendering the first input image in the output image by using a first mapping function for representing the input values in the vectors of output values, a predictor (120) configured for predicting the second input image from the first input image for obtaining a predicted second input image (104), a residual calculator (130) configured for calculating a residual image (106) from the second input image and the predicted second input image, the residual image comprising residual values representing prediction errors of the predicted second input image, and the rendering unit being further configured for rendering the residual image in the output image by using a second mapping function for representing the residual values in the vectors of output values, the second mapping function being different from the first mapping function for distinguishing the residual image from the first input image.
摘要翻译：用于在输出图像（108）中创建第一输入图像（101）和第二输入图像（102）的叠加呈现的图像处理装置（100），所述第一输入图像包括输入值，所述输出图像包括输出矢量值，表示输出图像的颜色的输出值的矢量，以及包括用于获得第一输入放映图像和第二输入图像的输入（110）的装置，被配置为将第一输入图像呈现在通过使用用于表示输出值的向量中的输入值的第一映射函数的输出图像，配置用于从第一输入图像预测第二输入图像以获得预测的第二输入图像的预测器（120），剩余计算器（130），被配置为从所述第二输入图像和所述预测的第二输入图像计算残差图像（106），所述残差图像包括表示预测误差的残差值所述预测的第二输入图像和所述绘制单元还被配置为通过使用用于表示所述输出值的向量中的残差的第二映射函数来呈现所述输出图像中的残差图像，所述第二映射函数不同于所述第一映射用于区分残差图像与第一输入图像的功能。

2. 发明授权

US09261441B2 Generating a slicing scheme for slicing a specimen 有权
标题翻译：生成用于切片的切片方案
公开(公告)号：US09261441B2
公开(公告)日：2016-02-16
申请号：US14116430
申请日：2012-05-08
申请人： Kirsten Meetz , Martin Bergtholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
发明人： Kirsten Meetz , Martin Bergtholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
IPC分类号： G06K9/00 , C12M1/00 , G01N1/31 , G01N1/06 , G06T7/00 , A61B10/00 , G01N1/28
CPC分类号： G01N1/31 , A61B10/0041 , G01N1/06 , G01N2001/2873 , G06T7/0012
摘要： A system for generating a slicing scheme for slicing a specimen is disclosed. A parameter unit (1) is arranged for determining at least one parameter of a lesion in a specimen, based on an image dataset (14) representing at least part of the specimen. A slicing scheme unit (2) is arranged for determining a slicing scheme (15) for pathologic examination of the specimen, based on the at least one parameter. A specimen preparation unit (3) is arranged for determining a slicing preparation protocol, based on the image dataset, wherein the slicing preparation protocol comprises a representation of preparation steps relating to the specimen. A segmentation unit (5) is arranged for segmenting the lesion in the image dataset (14), wherein the parameter unit (1) is arranged for determining the at least one parameter, based on the segmented lesion.
摘要翻译：公开了一种用于产生用于切片试样的切片方案的系统。基于表示至少部分样本的图像数据集（14），配置参数单元（1），用于确定样本中病变的至少一个参数。基于所述至少一个参数，设置切片方案单元（2），用于确定用于所述样本的病理检查的切片方案（15）。一种样本制备单元（3），用于基于图像数据集来确定切片制备方案，其中切片制备方案包括与试样有关的准备步骤的表示。分割单元（5）被布置用于分割图像数据集（14）中的病变，其中参数单元（1）被布置用于基于分割的病变确定至少一个参数。

3. 发明授权

US08934697B2 Image processing apparatus 有权
标题翻译：图像处理装置
公开(公告)号：US08934697B2
公开(公告)日：2015-01-13
申请号：US13988770
申请日：2011-11-22
申请人： Rafael Wiemker , Thomas Buelow , Martin Bergtholdt , Kirsten Meetz , Ingwer-Curt Carlsen
发明人： Rafael Wiemker , Thomas Buelow , Martin Bergtholdt , Kirsten Meetz , Ingwer-Curt Carlsen
IPC分类号： G06K9/00 , G06K9/32 , G06T11/60 , G06T11/00
CPC分类号： G06T11/60 , G06T11/00
摘要： Image processing apparatus (100) for creating an overlaid presentation of a first input image (101) and a second input image (102) in an output image (108), the first input image comprising input values, the output image comprising vectors of output values, the vectors of output values representing colors of the output image, and the apparatus comprising an input (110) for obtaining the first input put image and the second input image, a rendering unit (140) configured for rendering the first input image in the output image by using a first mapping function for representing the input values in the vectors of output values, a predictor (120) configured for predicting the second input image from the first input image for obtaining a predicted second input image (104), a residual calculator (130) configured for calculating a residual image (106) from the second input image and the predicted second input image, the residual image comprising residual values representing prediction errors of the predicted second input image, and the rendering unit being further configured for rendering the residual image in the output image by using a second mapping function for representing the residual values in the vectors of output values, the second mapping function being different from the first mapping function for distinguishing the residual image from the first input image.
摘要翻译：用于在输出图像（108）中创建第一输入图像（101）和第二输入图像（102）的叠加呈现的图像处理装置（100），所述第一输入图像包括输入值，所述输出图像包括输出矢量值，表示输出图像的颜色的输出值的矢量，以及包括用于获得第一输入放映图像和第二输入图像的输入（110）的装置，被配置为将第一输入图像呈现在通过使用用于表示输出值的向量中的输入值的第一映射函数的输出图像，配置用于从第一输入图像预测第二输入图像以获得预测的第二输入图像的预测器（120），剩余计算器（130），被配置为从所述第二输入图像和所述预测的第二输入图像计算残差图像（106），所述残差图像包括表示预测误差的残差值所述预测的第二输入图像和所述绘制单元还被配置为通过使用用于表示所述输出值的向量中的残差的第二映射函数来呈现所述输出图像中的残差图像，所述第二映射函数不同于所述第一映射用于区分残差图像与第一输入图像的功能。

4. 发明申请

US20140086463A1 GENERATING A SLICING SCHEME FOR SLICING A SPECIMEN 有权
标题翻译：生成一个样本的SLI方案
公开(公告)号：US20140086463A1
公开(公告)日：2014-03-27
申请号：US14116430
申请日：2012-05-08
申请人： Kirsten Meetz , Martin Bergholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
发明人： Kirsten Meetz , Martin Bergholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
IPC分类号： G01N1/31 , G06T7/00
CPC分类号： G01N1/31 , A61B10/0041 , G01N1/06 , G01N2001/2873 , G06T7/0012
摘要： A system for generating a slicing scheme for slicing a specimen is disclosed. A parameter unit (1) is arranged for determining at least one parameter of a lesion in a specimen, based on an image dataset (14) representing at least part of the specimen. A slicing scheme unit (2) is arranged for determining a slicing scheme (15) for pathologic examination of the specimen, based on the at least one parameter. A specimen preparation unit (3) is arranged for determining a slicing preparation protocol, based on the image dataset, wherein the slicing preparation protocol comprises a representation of preparation steps relating to the specimen. A segmentation unit (5) is arranged for segmenting the lesion in the image dataset (14), wherein the parameter unit (1) is arranged for determining the at least one parameter, based on the segmented lesion.
摘要翻译：公开了一种用于产生用于切片试样的切片方案的系统。基于表示至少部分样本的图像数据集（14），配置参数单元（1），用于确定样本中病变的至少一个参数。基于所述至少一个参数，设置切片方案单元（2），用于确定用于所述样本的病理检查的切片方案（15）。一种样本制备单元（3），用于基于图像数据集来确定切片制备方案，其中切片制备方案包括与试样有关的准备步骤的表示。分割单元（5）被布置用于分割图像数据集（14）中的病变，其中参数单元（1）被布置用于基于分割的病变确定至少一个参数。

5. 发明申请

US20130064437A1 HANDLING A SPECIMEN IMAGE 审中-公开
标题翻译：处理样本图像
公开(公告)号：US20130064437A1
公开(公告)日：2013-03-14
申请号：US13698905
申请日：2011-05-16
申请人： Kirsten Meetz , Thomas Buelow , Ingwer Curt Carlsen , Martin Bergtholdt
发明人： Kirsten Meetz , Thomas Buelow , Ingwer Curt Carlsen , Martin Bergtholdt
IPC分类号： G06K9/46
CPC分类号： G06T7/33 , G06T2207/10081 , G06T2207/10088 , G06T2207/10116 , G06T2207/10132 , G06T2207/10136 , G06T2207/30004 , G06T2207/30068 , G06T2207/30096
摘要： A system for handling a specimen image is disclosed. An image input (1) is configured to receive a body image representing at least a portion of a living body and a specimen image representing a dissected portion of the living body. An alignment unit (2) is configured to compute an alignment of the specimen image with the body image, based on image content of the specimen image and/or the body image. A border detector (3) is operatively connected to the alignment unit (2) and configured to detect at least part of an outer border of the dissected portion in the specimen image.
摘要翻译：公开了一种处理标本图像的系统。图像输入（1）被配置为接收表示生物体的至少一部分的身体图像和表示生物体的解剖部分的标本图像。对准单元（2）被配置为基于标本图像和/或身体图像的图像内容来计算样本图像与身体图像的对准。边界检测器（3）可操作地连接到对准单元（2）并且被配置为检测样本图像中的解剖部分的外部边界的至少一部分。

6. 发明申请

US20140143716A1 SYSTEM AND METHOD FOR PROCESSING A MEDICAL IMAGE 审中-公开
标题翻译：用于处理医学图像的系统和方法
公开(公告)号：US20140143716A1
公开(公告)日：2014-05-22
申请号：US14125635
申请日：2012-06-14
申请人： Thomas Buelow , Martin Bergtholdt , Kirsten Meetz , Ingwer-Curt Carlson , Rafael Wiemker
发明人： Thomas Buelow , Martin Bergtholdt , Kirsten Meetz , Ingwer-Curt Carlson , Rafael Wiemker
IPC分类号： G06F3/0484 , G06F3/0485
CPC分类号： G06F3/04845 , G06F3/0485 , G06T7/10 , G06T2207/20092 , G06T2207/20112
摘要： A system (100) for processing a medical image (102), the system being arranged for establishing a region of interest in the medical image, and the system comprising segmentation means (120) for applying a plurality of different segmentation methods (124) to the region of interest for obtaining an associated plurality of segmentation results (122), visualization means (140) for simultaneously displaying the plurality of segmentation results to a user, and a user input (160) for receiving from the user a selection command (162) indicative of a selection of one of the plurality of segmentation results for establishing an associated one of the plurality of different segmentation methods as a selected segmentation method (164).
摘要翻译：一种用于处理医学图像（102）的系统（100），所述系统被布置成用于在医学图像中建立感兴趣区域，并且所述系统包括分割装置（120），用于将多个不同的分割方法（124）应用于用于获得相关联的多个分割结果（122）的兴趣区域，用于将多个分割结果同时显示给用户的可视化装置（140）和用于从用户接收选择命令（162）的用户输入）指示所述多个分割结果之一的选择，用于建立所述多个不同分割方法中的相关联的分割方法作为所选择的分割方法（164）。

7. 发明申请

US20100246910A1 METHOD OF AUTOMATICALLY CORRECTING MIS-ORIENTATION OF MEDICAL IMAGES 审中-公开
标题翻译：自动校正医学影像的方法
公开(公告)号：US20100246910A1
公开(公告)日：2010-09-30
申请号：US12741838
申请日：2008-11-10
申请人： Rafael Wiemker , Thomas Buelow , Hans Barschdorf , Kirsten Meetz , Heinrich Schulz
发明人： Rafael Wiemker , Thomas Buelow , Hans Barschdorf , Kirsten Meetz , Heinrich Schulz
IPC分类号： G06K9/00
CPC分类号： G06T3/0068
摘要： This invention relates to a method and image processing apparatus for automatically correcting mis-orientation of medical images. One or more image processing software modules are used to extract (101) anatomical areas from the medical images. It is determined (103) whether the extracted anatomical areas correspond to reference anatomical areas, but the reference anatomical areas have associated thereto data indicating the orientation of the reference anatomical areas. If the extracted anatomical areas correspond with the reference anatomical areas, the true orientation of the extracted anatomical areas is determined (105) by realigning the medical image until the orientation of the extracted anatomical areas corresponds to the orientation of the reference anatomical areas.
摘要翻译：本发明涉及一种用于自动校正医学图像的错误取向的方法和图像处理装置。使用一个或多个图像处理软件模块从医学图像中提取（101）解剖区域。确定（103）所提取的解剖区域是否对应于参考解剖区域，但是参考解剖区域与其相关联地指示参考解剖区域的取向的数据。如果提取的解剖区域与参考解剖区域相对应，则通过重新对准医学图像来确定提取的解剖区域的真实取向（105），直到提取的解剖区域的取向对应于参考解剖区域的取向。

8. 发明授权

US09014448B2 Associating acquired images with objects 有权
标题翻译：将获取的图像与对象相关联
公开(公告)号：US09014448B2
公开(公告)日：2015-04-21
申请号：US13516576
申请日：2010-11-24
申请人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
发明人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
IPC分类号： G06K9/00 , G06F19/00
CPC分类号： G06F19/321 , G06F19/00 , G16H30/20
摘要： A system for associating acquired images with objects is disclosed. It comprises an image selector (1) for selecting a stored image from a database (5) comprising a plurality of stored images, the database (5) comprising an association (21) between the stored image (6) and an object of interest; an image scanner (2) for acquiring a new image (9) comprising a representation (10) of at least part of the object of interest, during an imaging session; a user interface (3) for enabling a user, during the imaging session, to indicate that the new image (9) is to be associated with the object of interest; and an associating subsystem (4) for creating an association (23) between the new image (9) and the object of interest in the database. The user interface (3) is arranged for enabling a user to select the object of interest from a plurality of objects of interest associated with the stored image (6).
摘要翻译：公开了一种用于将获取的图像与对象相关联的系统。它包括用于从包括多个存储的图像的数据库（5）中选择存储的图像的图像选择器（1），所述数据库（5）包括存储的图像（6）和感兴趣对象之间的关联（21）用于在成像会话期间获取包括所述感兴趣对象的至少一部分的表示（10）的新图像（9）的图像扫描仪（2）用于在成像会话期间使用户能够指示新图像（9）与感兴趣对象相关联的用户界面（3）以及用于在新图像（9）和数据库中的感兴趣对象之间创建关联（23）的关联子系统（4）。用户界面（3）被布置为使得用户能够从与所存储的图像（6）相关联的多个感兴趣对象中选择感兴趣的对象。

9. 发明申请

US20120243765A1 ASSOCIATING ACQUIRED IMAGES WITH OBJECTS 有权
标题翻译：与对象相关的获取图像
公开(公告)号：US20120243765A1
公开(公告)日：2012-09-27
申请号：US13516576
申请日：2010-11-24
申请人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
发明人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
IPC分类号： G06K9/00
CPC分类号： G06F19/321 , G06F19/00 , G16H30/20
摘要： A system for associating acquired images with objects is disclosed. It comprises an image selector (1) for selecting a stored image from a database (5) comprising a plurality of stored images, the database (5) comprising an association (21) between the stored image (6) and an object of interest; an image scanner (2) for acquiring a new image (9) comprising a representation (10) of at least part of the object of interest, during an imaging session; a user interface (3) for enabling a user, during the imaging session, to indicate that the new image (9) is to be associated with the object of interest; and an associating subsystem (4) for creating an association (23) between the new image (9) and the object of interest in the database. The user interface (3) is arranged for enabling a user to select the object of interest from a plurality of objects of interest associated with the stored image (6).
摘要翻译：公开了一种用于将获取的图像与对象相关联的系统。它包括用于从包括多个存储的图像的数据库（5）中选择存储的图像的图像选择器（1），所述数据库（5）包括存储的图像（6）和感兴趣对象之间的关联（21）用于在成像会话期间获取包括所述感兴趣对象的至少一部分的表示（10）的新图像（9）的图像扫描器（2）用于在成像会话期间使用户能够指示新图像（9）与感兴趣对象相关联的用户界面（3）以及用于在新图像（9）和数据库中的感兴趣对象之间创建关联（23）的关联子系统（4）。用户界面（3）被布置为使得用户能够从与所存储的图像（6）相关联的多个感兴趣对象中选择感兴趣的对象。

10. 发明授权

US09757083B2 Scanning method and system 有权
公开(公告)号：US09757083B2
公开(公告)日：2017-09-12
申请号：US12809080
申请日：2008-12-26
申请人： Kirsten Meetz , Ingwer Curt Carlsen
发明人： Kirsten Meetz , Ingwer Curt Carlsen
IPC分类号： A61B6/00
CPC分类号： A61B6/504 , A61B6/501
摘要： To improve the scanning effect, a scanning method is provided, which comprises the steps of performing at least one of an nCT scan and a CTA scan on an object so as to obtain a set of images; detecting characteristics of a region of interest based on the set of images; and performing a CTP scan on the region of interest by adopting the characteristics to obtain a CTP image. By deriving the characteristics of the region of interest, e.g. a lesion or an area covering the lesion, before performing the CTP scan, and by adapting the subsequent CTP scan based on the characteristics of the region of interest, the drawback introduced by a limited scan area of the CTP scanner is mitigated, or even overcome.

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