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1. 发明申请

US20230133142A1 PATIENT STRATIFICATION AND CLINICAL DECISION SUPPORT ON MECHANICAL VENTILATION SETTINGS FROM SONAR RESPONSES THROUGH AN ENDOTRACHEAL TUBE (ETT) 有权
公开(公告)号：US20230133142A1
公开(公告)日：2023-05-04
申请号：US17960167
申请日：2022-10-05
申请人： Rafael Wiemker , Joerg Sabczynski , Thomas Koehler , Cornelis Petrus Hendriks , Roberto Buizza , Jaap Roger Haartsen , Stefan Winter , Michael Polkey , Rita Priori , Nataly Wieberneit , Kiran Hamilton J. Dellimore
发明人： Rafael Wiemker , Joerg Sabczynski , Thomas Koehler , Cornelis Petrus Hendriks , Roberto Buizza , Jaap Roger Haartsen , Stefan Winter , Michael Polkey , Rita Priori , Nataly Wieberneit , Kiran Hamilton J. Dellimore
IPC分类号： A61M16/00 , A61M16/04
摘要： A respiration monitoring device comprises an electronic controller configured to: receive an audio signal that is acoustically coupled with an airway of a patient receiving mechanical ventilation therapy from a mechanical ventilator; map the audio signal to one or more lung disease or injury condition categories; and at least one of: display the mapped one or more lung disease or injury condition categories on a display device; and determine a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient based at least on the mapped lung disease or injury condition categories and displaying the recommended adjustment on the display device.

2. 发明授权

US09483844B2 Interactive image analysis 有权
标题翻译：交互式图像分析
公开(公告)号：US09483844B2
公开(公告)日：2016-11-01
申请号：US13806301
申请日：2011-06-28
申请人： Rafael Wiemker , Thomas Buelow , Sebastian Peter Michael Dries
发明人： Rafael Wiemker , Thomas Buelow , Sebastian Peter Michael Dries
IPC分类号： G06T7/60 , G06F19/00
CPC分类号： G06T7/60 , G06F19/00 , G06F19/321
摘要： An interactive image analysis system includes an image visualization subsystem (1) for visualizing an image (8). An indicated position determiner (2) is arranged for determining an indicated position of a pointing device with respect to the image(8). A result determiner (3) is arranged for determining a result of a local image processing of the image (8) at the indicated position. A display subsystem (4) displays either at least part of the result of the local image processing (406) or a visible mark (407), based on the image processing result. The result of the local image processing is indicative of the presence or absence of an object (403) at or near the indicated position (404, 405), and the display subsystem (4) is arranged for displaying the visible mark (407) in the absence of such an object (403) at or near the indicated position (405).
摘要翻译：交互式图像分析系统包括用于可视化图像（8）的图像可视化子系统（1）。指示位置确定器（2）被布置用于确定指示设备相对于图像（8）的指示位置。结果确定器（3）被布置用于确定在所指示的位置处的图像（8）的局部图像处理的结果。显示子系统（4）基于图像处理结果显示局部图像处理（406）的结果的至少一部分或可见标记（407）。本地图像处理的结果表示在指示位置（404,405）处或附近存在或不存在对象（403），并且显示子系统（4）被布置用于将显示标记（407）显示在在指示位置（405）处或附近没有这样的物体（403）。

3. 发明授权

US09261441B2 Generating a slicing scheme for slicing a specimen 有权
标题翻译：生成用于切片的切片方案
公开(公告)号：US09261441B2
公开(公告)日：2016-02-16
申请号：US14116430
申请日：2012-05-08
申请人： Kirsten Meetz , Martin Bergtholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
发明人： Kirsten Meetz , Martin Bergtholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
IPC分类号： G06K9/00 , C12M1/00 , G01N1/31 , G01N1/06 , G06T7/00 , A61B10/00 , G01N1/28
CPC分类号： G01N1/31 , A61B10/0041 , G01N1/06 , G01N2001/2873 , G06T7/0012
摘要： A system for generating a slicing scheme for slicing a specimen is disclosed. A parameter unit (1) is arranged for determining at least one parameter of a lesion in a specimen, based on an image dataset (14) representing at least part of the specimen. A slicing scheme unit (2) is arranged for determining a slicing scheme (15) for pathologic examination of the specimen, based on the at least one parameter. A specimen preparation unit (3) is arranged for determining a slicing preparation protocol, based on the image dataset, wherein the slicing preparation protocol comprises a representation of preparation steps relating to the specimen. A segmentation unit (5) is arranged for segmenting the lesion in the image dataset (14), wherein the parameter unit (1) is arranged for determining the at least one parameter, based on the segmented lesion.
摘要翻译：公开了一种用于产生用于切片试样的切片方案的系统。基于表示至少部分样本的图像数据集（14），配置参数单元（1），用于确定样本中病变的至少一个参数。基于所述至少一个参数，设置切片方案单元（2），用于确定用于所述样本的病理检查的切片方案（15）。一种样本制备单元（3），用于基于图像数据集来确定切片制备方案，其中切片制备方案包括与试样有关的准备步骤的表示。分割单元（5）被布置用于分割图像数据集（14）中的病变，其中参数单元（1）被布置用于基于分割的病变确定至少一个参数。

4. 发明授权

US09129360B2 Visualization apparatus for visualizing an image data set 有权
标题翻译：用于可视化图像数据集的可视化装置
公开(公告)号：US09129360B2
公开(公告)日：2015-09-08
申请号：US13376213
申请日：2010-06-02
申请人： Rafael Wiemker , Thomas Buelow , Cristian Lorenz , Torbjorn Vik , Sven Kabus
发明人： Rafael Wiemker , Thomas Buelow , Cristian Lorenz , Torbjorn Vik , Sven Kabus
IPC分类号： G09G5/02 , G06T7/00 , G06T11/00 , G06T19/00
CPC分类号： G06T7/0012 , G06T11/001 , G06T19/00 , G06T2200/24 , G06T2207/10081 , G06T2207/10088 , G06T2207/10132 , G06T2207/20021 , G06T2207/20092 , G06T2207/30064 , G06T2210/41 , G06T2219/028 , G06T2219/2012
摘要： The invention relates to a visualization apparatus (1) for visualizing an image data set. The visualization apparatus (1) comprises an image data set providing unit (2) for providing the image data set, a differential property determination unit (5) for determining local differential properties for different regions of the image data set, an assigning unit (6) for assigning visualization properties to the different regions of the image data set depending on the determined local differential properties, wherein a visualization property defines the visualization of a region, to which the visualization property is assigned, and a display unit (7) for displaying the visualization properties assigned to the different regions of the image data set. By displaying the visualization properties assigned to the different regions of the image data set different objects can visually be separated from each other without requiring large computational costs.
摘要翻译：本发明涉及一种用于可视化图像数据集的可视化装置（1）。可视化装置（1）包括用于提供图像数据组的图像数据集提供单元（2），用于确定图像数据组的不同区域的局部差分属性的差分特性确定单元（5），分配单元），用于根据所确定的本地差分属性将可视化属性分配给图像数据集的不同区域，其中可视化属性定义可分配可视化属性的区域的可视化，以及用于显示的显示单元（7）分配给图像数据集的不同区域的可视化属性。通过显示分配给图像数据集的不同区域的可视化属性，不同的对象可以在视觉上彼此分离，而不需要大的计算成本。

5. 发明授权

US08787634B2 Apparatus and method for indicating likely computer-detected false positives in medical imaging data 有权
标题翻译：用于在医学成像数据中指示可能的计算机检测到的假阳性的装置和方法
公开(公告)号：US08787634B2
公开(公告)日：2014-07-22
申请号：US12519799
申请日：2007-12-14
申请人： Rafael Wiemker , Roland Opfer , Thomas Buelow
发明人： Rafael Wiemker , Roland Opfer , Thomas Buelow
IPC分类号： G06K9/00 , G06K9/36 , G06K9/46
CPC分类号： G06T7/0012 , G06T2207/30061
摘要： A data structure for use by a computer system for processing medical image data and representing at least one first region of a patient includes at least one computer-detected feature of interest. The data structure includes a first computer code that is executable to detect first data representing at least one second region included within a respective first region. At least one said feature of interest in said second region has a significant likelihood of representing a computer-detected false positive. The second computer code is executable to provide second data for enabling at least one said first region to be displayed on a display device, such that at least one said second region is displayed on the display apparatus differently from part of said first region not containing features of interest having a significant likelihood of representing computer-detected false positives.
摘要翻译：由计算机系统用于处理医学图像数据并且表示患者的至少一个第一区域的数据结构包括至少一个计算机检测到的感兴趣特征。数据结构包括第一计算机代码，其可执行以检测表示包括在相应的第一区域内的至少一个第二区域的第一数据。所述第二区域中至少一个所述感兴趣的特征具有表示计算机检测到的假阳性的显着可能性。第二计算机代码可执行以提供第二数据，用于使至少一个所述第一区域能够显示在显示设备上，使得至少一个所述第二区域不显示在所述显示设备上，不同于所述第一区域的不包含特征具有代表计算机检测到的误报的显着可能性。

6. 发明授权

US08699768B2 Scan plan field of view adjustor, determiner, and/or quality assessor 有权
公开(公告)号：US08699768B2
公开(公告)日：2014-04-15
申请号：US13508370
申请日：2010-10-14
申请人： Torbjorn Vik , Jorg Bredno , Rafael Wiemker , Mark E. Olszewski
发明人： Torbjorn Vik , Jorg Bredno , Rafael Wiemker , Mark E. Olszewski
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T7/0012 , A61B5/0037 , A61B5/055 , A61B5/7207 , A61B6/032 , A61B6/12 , A61B6/488 , A61B6/5264 , G06T7/32 , G06T7/344 , G06T2207/10081 , G06T2207/30004
摘要： A method includes using a pre-scan image to define a scan field of view for a region of interest of a patient to be scanned for at least one image acquisition of a series of image acquisitions of a scan plan, performing an image acquisition of the series based on a corresponding scan field of view for the image acquisition, and determining, via a processor (120), a next field of view for a next image acquisition of the series based on available image related data.

7. 发明申请

US20120143623A1 RULE BASED DECISION SUPPORT AND PATIENT-SPECIFIC VISUALIZATION SYSTEM FOR OPTIMAL CANCER STAGING 审中-公开
标题翻译：基于规则的决策支持和患者特异性可视化系统，用于最佳癌症分期
公开(公告)号：US20120143623A1
公开(公告)日：2012-06-07
申请号：US13382013
申请日：2010-06-15
申请人： Roland Johannes Opfer , Cristian Lorenz , Rafael Wiemker , Lothar Spies , Guy Shechter
发明人： Roland Johannes Opfer , Cristian Lorenz , Rafael Wiemker , Lothar Spies , Guy Shechter
IPC分类号： G06Q50/22
CPC分类号： G06T7/0012 , G06Q50/22 , G06T2200/24 , G06T2207/30061
摘要： A system including a display and a processor and a corresponding method for identifying a tumor in a patient image, classifying the tumor based on a predetermined classification system and determining a recommendation regarding a lymph node biopsy based on the tumor identified in the patient image, the classification of the tumor and a predetermined rule.
摘要翻译：一种包括显示器和处理器的系统以及用于识别患者图像中的肿瘤的相应方法，基于预定分类系统对肿瘤进行分类，并基于在患者图像中识别的肿瘤确定关于淋巴结活检的建议，肿瘤分类和预定规则。

8. 发明授权

US08107707B2 Visualizing a vascular structure 有权
标题翻译：可视化血管结构
公开(公告)号：US08107707B2
公开(公告)日：2012-01-31
申请号：US12516670
申请日：2007-11-27
申请人： Rafael Wiemker , Roland Opfer , Thomas Buelow
发明人： Rafael Wiemker , Roland Opfer , Thomas Buelow
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/032 , A61B6/12 , A61B6/481 , A61B6/503 , G06T7/0012 , G06T2207/10081 , G06T2207/30104
摘要： A system (500) for visualizing a vascular structure represented by a three-dimensional angiography dataset is disclosed. Respective voxel values are associated with respective voxels. The dataset represents a vascular structure. The system comprises means (502) for establishing respective filling values; means (504) for identifying respective minimum filling values; means (506) for computing respective deficiency values; and an output (514) for providing a visualization in dependence on the deficiency values. A respective filling value is indicative of an amount of blood flow at the respective position in the vascular structure. A respective minimum filling value is a minimum of the filling values associated with the positions upstream of the respective position. A respective deficiency value is indicative of a difference between the filling value associated with the respective position and the minimum filling value associated with the respective position.
摘要翻译：公开了一种用于可视化由三维血管造影数据集表示的血管结构的系统（500）。各个体素值与相应的体素相关联。数据集表示血管结构。该系统包括用于建立相应填充值的装置（502）用于识别相应的最小填充值的装置（504）; 用于计算各个不足值的装置（506）; 以及用于根据不足值提供可视化的输出（514）。相应的填充值表示血管结构中各个位置处的血流量。相应的最小填充值是与相应位置的上游位置相关联的填充值的最小值。相应的缺陷值表示与各个位置相关联的填充值与与各个位置相关联的最小填充值之间的差异。

9. 发明申请

US20100246910A1 METHOD OF AUTOMATICALLY CORRECTING MIS-ORIENTATION OF MEDICAL IMAGES 审中-公开
标题翻译：自动校正医学影像的方法
公开(公告)号：US20100246910A1
公开(公告)日：2010-09-30
申请号：US12741838
申请日：2008-11-10
申请人： Rafael Wiemker , Thomas Buelow , Hans Barschdorf , Kirsten Meetz , Heinrich Schulz
发明人： Rafael Wiemker , Thomas Buelow , Hans Barschdorf , Kirsten Meetz , Heinrich Schulz
IPC分类号： G06K9/00
CPC分类号： G06T3/0068
摘要： This invention relates to a method and image processing apparatus for automatically correcting mis-orientation of medical images. One or more image processing software modules are used to extract (101) anatomical areas from the medical images. It is determined (103) whether the extracted anatomical areas correspond to reference anatomical areas, but the reference anatomical areas have associated thereto data indicating the orientation of the reference anatomical areas. If the extracted anatomical areas correspond with the reference anatomical areas, the true orientation of the extracted anatomical areas is determined (105) by realigning the medical image until the orientation of the extracted anatomical areas corresponds to the orientation of the reference anatomical areas.
摘要翻译：本发明涉及一种用于自动校正医学图像的错误取向的方法和图像处理装置。使用一个或多个图像处理软件模块从医学图像中提取（101）解剖区域。确定（103）所提取的解剖区域是否对应于参考解剖区域，但是参考解剖区域与其相关联地指示参考解剖区域的取向的数据。如果提取的解剖区域与参考解剖区域相对应，则通过重新对准医学图像来确定提取的解剖区域的真实取向（105），直到提取的解剖区域的取向对应于参考解剖区域的取向。

10. 发明申请

US20100128940A1 METHOD OF AUTOMATIC EXTRACTION OF THE PULMONARY ARTERY TREE FROM 3D MEDICAL IMAGES 有权
标题翻译：从三维医学图像中自动提取脉络膜的方法
公开(公告)号：US20100128940A1
公开(公告)日：2010-05-27
申请号：US11815662
申请日：2006-02-06
申请人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
发明人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
IPC分类号： G06K9/62
CPC分类号： G06T7/155 , G06T7/11 , G06T7/149 , G06T2200/04 , G06T2207/10081 , G06T2207/20044 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： An automated method (1) for the automatic extraction of a pulmonary vessel tree from a 3D medical image, such as multi-slice CT data, is disclosed. A segmented pulmonary vessel is identified as either an artery or a vein by determining a measure for arterialness for the vessel. The measure is based on a relation of the orientation of a local bronchus to the orientation of the segmented pulmonary vessel of the local bronchus. When a vessel is identified as a pulmonary artery, it is added to the pulmonary artery tree. Radii of the pulmonary artery and bronchus are measured automatically and positions where a ratio of these radii exhibits unusual values are presented in a display, preferably for suggesting further assessment by a radiologist, which for instance is useful for pulmonary embolism detection.
摘要翻译：公开了一种用于从诸如多层CT数据的3D医学图像自动提取肺血管树的自动化方法（1）。通过确定血管动脉的测量，将分段的肺血管识别为动脉或静脉。该措施基于局部支气管的取向与局部支气管的分段肺血管的取向的关系。当血管被识别为肺动脉时，将其加入肺动脉树。自动测量肺动脉和支气管的半径，并且在显示中呈现这些半径的比率显示出异常值的位置，优选用于暗示例如用于肺栓塞检测的放射科医师的进一步评估。

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