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1. 发明授权

US11106726B2 Systems and methods for an image repository for pathology 有权
公开(公告)号：US11106726B2
公开(公告)日：2021-08-31
申请号：US16902086
申请日：2020-06-15
申请人： LEICA BIOSYSTEMS IMAGING, INC.
发明人： Ole Eichhorn , Dirk Soenksen
IPC分类号： G06F16/58 , G06F16/54 , G06Q10/10 , G06Q30/06 , G16H30/20 , G16H30/40 , G16H70/00 , G06Q20/14 , G16Z99/00
摘要： Systems and methods for managing an image repository for pathology. In an embodiment, a search request is received. One or more digital slide images are identified from an image repository based on the search request. A user is provided access to the identified digital slide images. In addition, each of a plurality of collections of digital slide images are associated with a search rating, and a value for each of the plurality of collections is computed based on the associated search rating and a size of the collection.

2. 发明授权

US10685056B2 Systems and methods for an image repository for pathology 有权
公开(公告)号：US10685056B2
公开(公告)日：2020-06-16
申请号：US14437821
申请日：2013-03-15
申请人： LEICA BIOSYSTEMS IMAGING, INC.
发明人： Ole Eichhorn , Dirk Soenksen
IPC分类号： G06F16/58 , G06F16/54 , G06F19/00 , G06Q10/10 , G06Q30/06 , G06Q50/22
摘要： Systems and methods for managing an image repository for pathology. In an embodiment, a search request is received. One or more digital slide images are identified from an image repository based on the search request. A user is provided access to the identified digital slide images. In addition, each of a plurality of collections of digital slide images are associated with a search rating, and a value for each of the plurality of collections is computed based on the associated search rating and a size of the collection.

3. 发明授权

US09910961B2 Second opinion network 有权
公开(公告)号：US09910961B2
公开(公告)日：2018-03-06
申请号：US14060522
申请日：2013-10-22
申请人： Leica Biosystems Imaging, Inc.
发明人： Dirk G. Soenksen , Kathy Zirker-Smith , Ole Eichhorn
IPC分类号： G06Q10/00 , G06Q50/00 , G06F19/00
CPC分类号： G16H80/00 , G06F19/00 , G06F19/321 , G16H50/50
摘要： Systems and methods are provided to facilitate consultations between a referral source (e.g., labs, pathologists and patients) and a consultant (e.g., pathologist, radiologist, or other digital image analyst). Links between the various referral sources and consultants are established through a scanning center via a data communication network such as the Internet. The referral source sends a slide to the scanning center where the corresponding digital slide is posted for review and analysis by the consultant. Upon completion of the analysis and report, a digital slide conference is conducted through the scanning center that provides a venue for direct communication regarding the consultation. The scanning center may also facilitate payment from the referral source to the consultant.

4. 发明授权

US09723036B2 Viewing digital slides 有权
公开(公告)号：US09723036B2
公开(公告)日：2017-08-01
申请号：US14077979
申请日：2013-11-12
申请人： Leica Biosystems Imaging, Inc.
发明人： Ole Eichhorn , Anne Brumme
IPC分类号： H04L29/06 , G06F17/24 , G06F3/14 , G02B21/26 , G02B21/32 , G06F17/30 , G06F19/00 , G06Q50/24
CPC分类号： H04L65/403 , G02B21/26 , G02B21/32 , G06F3/1454 , G06F17/241 , G06F17/30905 , G06F19/00 , G06F19/321 , G06Q50/24
摘要： A system for collaborative viewing of a digital slide image. In an embodiment, a session is established for viewing a digital slide image by a plurality of client viewers. A leader client viewer and non-leader client viewers are identified for the session. When a command is received from the leader client viewer, the command is sent to each of the non-leader client viewers to synchronize a view of the digital slide image at the non-leader client viewers with the view of the digital slide image at the leader client viewer.

5. 发明授权

US09152654B2 System and method for managing images over a network 有权
标题翻译：通过网络管理图像的系统和方法
公开(公告)号：US09152654B2
公开(公告)日：2015-10-06
申请号：US14273821
申请日：2014-05-09
申请人： Leica Biosystems Imaging, Inc.
发明人： Ole Eichhorn
IPC分类号： G06F17/30
CPC分类号： G06F17/30277 , G06F17/30106 , G06F17/3028 , Y10S707/915 , Y10S707/966
摘要： Systems, methods, and computer-readable media for managing image files over a network. In an embodiment, a notification is received from a remote server. The notification may comprise an identifier of an image file that comprises scanned slide data and is stored at the remote server. In response to the notification, the identifier of the image file may be added in association with an indication that the image file is stored at the remote server to a stored catalog of image files, and a file-transfer operation may be initiated to transfer a copy of the image file from the remote server to a central database. Following completion of the file-transfer operation, the stored catalog may be updated to indicate that the image file is stored in the central database, and a request may be sent to the remote server to delete the image file at the remote server.
摘要翻译：用于通过网络管理图像文件的系统，方法和计算机可读介质。在一个实施例中，从远程服务器接收到通知。该通知可以包括包括扫描的幻灯片数据并存储在远程服务器的图像文件的标识符。响应于通知，可以将图像文件的标识符与图像文件存储在远程服务器上的指示相关联地添加到存储的图像文件目录中，并且可以启动文件传送操作以传送图像文件从远程服务器复制到中央数据库。在完成文件传输操作之后，可以更新存储的目录以指示图像文件存储在中央数据库中，并且可以向远程服务器发送请求以在远程服务器上删除图像文件。

6. 发明申请

US20140333613A1 VIEWING THREE DIMENSIONAL DIGITAL SLIDES 有权
标题翻译：查看三维数字滑块
公开(公告)号：US20140333613A1
公开(公告)日：2014-11-13
申请号：US14341577
申请日：2014-07-25
申请人： Leica Biosystems Imaging, Inc.
发明人： Ole Eichhorn
IPC分类号： G06T15/08 , G06T5/50
CPC分类号： G06T15/00 , G02B21/34 , G02B21/367 , G06T5/50 , G06T15/08 , G06T15/10 , G06T2207/20212 , G06T2207/20224 , G06T2207/30024 , G06T2207/30056
摘要： Systems, methods, and media for providing a view of a digital slide image. In an embodiment, a digital slide image file is accessed. The digital slide image file may comprise a plurality of first image planes representing an image of at least a portion of a slide specimen at varying focal depths. Then, a three-dimensional object is constructed from the digital slide image file. The three-dimensional image object is constructed by determining a surface that crosses two or more of the plurality of first image planes, and determining image data that are interior to the determined surface, based on one or more of the plurality of first image planes. A view is generated from the three-dimensional image object.
摘要翻译：用于提供数字幻灯片图像视图的系统，方法和媒体。在一个实施例中，访问数字幻灯片图像文件。数字幻灯片图像文件可以包括表示在变化的焦点深度处的幻灯片样本的至少一部分的图像的多个第一图像平面。然后，从数字幻灯片图像文件构建三维物体。通过基于所述多个第一图像平面中的一个或多个，确定穿过所述多个第一图像平面中的两个或更多个的表面，以及确定位于所确定的表面内部的图像数据来构造所述三维图像对象。从三维图像对象生成视图。

7. 发明申请

US20140294266A1 System and Method To Determine Slide Quality of a Digitized Microscope Slide 有权
标题翻译：确定数字化显微镜幻灯片的幻灯片质量的系统和方法
公开(公告)号：US20140294266A1
公开(公告)日：2014-10-02
申请号：US14305124
申请日：2014-06-16
申请人： Leica Biosystems Imaging, Inc.
发明人： Ole Eichhorn , Cindy Perz
IPC分类号： G06K9/00
CPC分类号： G06K9/00127 , G06T7/0004 , G06T2207/10056 , G06T2207/20021 , G06T2207/30024 , G06T2207/30168 , H04N19/60 , H04N19/86
摘要： Methods, media, and systems for assessing the quality of a digital image. In an embodiment, both a micro-analysis and macro-analysis are performed. The micro-analysis comprises dividing the digital image into a plurality of blocks, for two or more of the plurality of blocks, determining a score based on a spatial frequency of the block, and generating a score map for the digital image based on the score for each of the two or more blocks. The macro-analysis comprises detecting artifacts in the digital image, computing a degradation score based on detected artifacts, and computing a whole-slide-quality score based on the score map and the degradation score.
摘要翻译：用于评估数字图像质量的方法，媒体和系统。在一个实施例中，执行微分析和宏观分析。微分析包括将数字图像划分为多个块中的两个或多个块的多个块，基于块的空间频率确定分数，以及基于分数生成数字图像的分数图对于两个或更多个块中的每一个。宏观分析包括检测数字图像中的伪像，基于检测到的伪像计算劣化得分，以及基于得分图和劣化得分计算全幻灯片质量得分。

8. 发明授权

US11211170B2 Second opinion network 有权
公开(公告)号：US11211170B2
公开(公告)日：2021-12-28
申请号：US15912428
申请日：2018-03-05
申请人： Leica Biosystems Imaging, Inc.
发明人： Dirk G. Soenksen , Kathy Zirker-Smith , Ole Eichhorn
IPC分类号： G16H80/00 , G16H30/20 , G16H50/50
摘要： Systems and methods are provided to facilitate consultations between a referral source (e.g., labs, pathologists and patients) and a consultant (e.g., pathologist, radiologist, or other digital image analyst). Links between the various referral sources and consultants are established through a scanning center via a data communication network such as the Internet. The referral source sends a slide to the scanning center where the corresponding digital slide is posted for review and analysis by the consultant. Upon completion of the analysis and report, a digital slide conference is conducted through the scanning center that provides a venue for direct communication regarding the consultation. The scanning center may also facilitate payment from the referral source to the consultant.

9. 发明授权

US09521309B2 Data management in a linear-array-based microscope slide scanner 有权
标题翻译：基于线性阵列的显微镜幻灯片扫描仪中的数据管理
公开(公告)号：US09521309B2
公开(公告)日：2016-12-13
申请号：US14275084
申请日：2014-05-12
申请人： Leica Biosystems Imaging, Inc.
发明人： Greg J. Crandall , Ole Eichhorn , Allen H. Olson , Dirk G. Soenksen
IPC分类号： G06K9/00 , H04N5/232 , H04N7/18 , G02B21/00 , G02B21/26 , G02B21/32 , G02B21/34 , G02B21/36 , G02B21/24
CPC分类号： G02B21/367 , G02B21/002 , G02B21/0036 , G02B21/008 , G02B21/14 , G02B21/245 , G02B21/26 , G02B21/32 , G02B21/34 , G02B21/365 , G06F19/00 , H04N1/053 , H04N1/1903 , H04N1/193 , H04N1/19573 , H04N5/2256 , H04N5/23206 , H04N7/18 , H04N7/183 , H04N2201/04727 , H04N2201/04755
摘要： Systems and methods for capturing image data using a line scan camera. In an embodiment, a line scan camera captures image data of a sample as a plurality of image stripes. A processor may coarsely align two or more of the plurality of image stripes according to a synchronization process while the line scan camera is capturing at least one of the plurality of image stripes. Subsequently, the processor may also finely align the two or more image stripes using pattern matching.
摘要翻译：使用线扫描相机拍摄图像数据的系统和方法。在一个实施例中，行扫描照相机将样本的图像数据捕获为多个图像条纹。当行扫描相机正在捕获多个图像条纹中的至少一个时，处理器可以根据同步处理粗略对准多个图像条纹中的两个或更多个。随后，处理器还可以使用模式匹配来精细对准两个或更多图像条纹。

10. 发明授权

US09349208B2 Viewing three dimensional digital slides 有权
标题翻译：查看三维数字幻灯片
公开(公告)号：US09349208B2
公开(公告)日：2016-05-24
申请号：US14341577
申请日：2014-07-25
申请人： Leica Biosystems Imaging, Inc.
发明人： Ole Eichhorn
IPC分类号： G06K9/00 , G06T15/00 , G02B21/34 , G02B21/36 , G06T15/08 , G06T15/10 , G06T5/50
CPC分类号： G06T15/00 , G02B21/34 , G02B21/367 , G06T5/50 , G06T15/08 , G06T15/10 , G06T2207/20212 , G06T2207/20224 , G06T2207/30024 , G06T2207/30056
摘要： Systems, methods, and media for providing a view of a digital slide image. In an embodiment, a digital slide image file is accessed. The digital slide image file may comprise a plurality of first image planes representing an image of at least a portion of a slide specimen at varying focal depths. Then, a three-dimensional object is constructed from the digital slide image file. The three-dimensional image object is constructed by determining a surface that crosses two or more of the plurality of first image planes, and determining image data that are interior to the determined surface, based on one or more of the plurality of first image planes. A view is generated from the three-dimensional image object.
摘要翻译：用于提供数字幻灯片图像视图的系统，方法和媒体。在一个实施例中，访问数字幻灯片图像文件。数字幻灯片图像文件可以包括表示在变化的焦点深度处的幻灯片样本的至少一部分的图像的多个第一图像平面。然后，从数字幻灯片图像文件构建三维物体。通过基于所述多个第一图像平面中的一个或多个，确定穿过所述多个第一图像平面中的两个或更多个的表面，以及确定位于所确定的表面内部的图像数据来构造所述三维图像对象。从三维图像对象生成视图。

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