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1. 发明申请

US20110010910A1 BRONCHIAL FLOW CONTROL DEVICES AND METHODS OF USE 有权
公开(公告)号：US20110010910A1
公开(公告)日：2011-01-20
申请号：US12820393
申请日：2010-06-22
申请人： Michael J. Hendricksen , Michael Barrett
发明人： Michael J. Hendricksen , Michael Barrett
IPC分类号： B23P11/00
CPC分类号： A61F2/04 , A61B17/12104 , A61B17/12172 , A61B17/12177 , A61F2002/043 , Y10T29/49826
摘要： Disclosed is an assembly for loading a bronchial flow control device into a container, such as into a delivery catheter. The assembly includes a funnel housing and a puller housing that mate with one another. The funnel housing defines a funnel-shaped loading cavity that receives a flow control device and that gradually reduces in size moving in a first direction. The puller housing is removably attached to the funnel housing and is also removably attachable to a bronchial flow control device that can be positioned in the loading cavity. The puller housing pulls the bronchial flow control device in the first direction through the funnel housing to gradually contract the bronchial flow control device into a compressed state of reduced size relative to the expanded size.
摘要翻译：公开了一种用于将支气管流量控制装置装载到诸如输送导管之类的容器中的组件。该组件包括一个漏斗壳体和一个相互配合的拔出器壳体。漏斗壳体限定漏斗形加载腔，其接纳流量控制装置，并逐渐减小尺寸沿第一方向移动。牵引器壳体可移除地附接到漏斗壳体，并且还可移除地附接到能够定位在加载腔中的支气管流量控制装置。牵引器壳体通过漏斗壳体沿着第一方向拉动支气管流量控制装置，以逐渐将支气管流量控制装置收缩成相对于膨胀尺寸减小尺寸的压缩状态。

2. 发明授权

US07036509B2 Multiple seal port anesthesia adapter 有权
标题翻译：多重密封口麻醉适配器
公开(公告)号：US07036509B2
公开(公告)日：2006-05-02
申请号：US11004560
申请日：2004-12-03
申请人： Alan R. Rapacki , Michael Barrett , Michael J. Hendricksen , Ronald R. Hundertmark
发明人： Alan R. Rapacki , Michael Barrett , Michael J. Hendricksen , Ronald R. Hundertmark
IPC分类号： A61M16/00 , A62B9/04
CPC分类号： A61M16/0463 , A61B2017/3466 , A61M16/01
摘要： Disclosed is an anesthesia adapter that is suitable for the simultaneous insertion of multiple devices or instruments into the lungs during ventilation of the patient, while minimizing or eliminating gas leaks. The anesthesia adapter comprises in one embodiment a first port sized to receive a first elongate instrument; a second port sized to receive a second elongate instrument; an endotrachial tube fitting configured to be coupled to an endotrachial tube, the endotrachial tube fitting fluidly coupled to the first and second ports; and a hose fitting configured to be coupled to a ventilator hose, the hose fitting fluidly coupled to the first and second ports. The first port seals around the first elongated instrument and the second port seals around the second elongate instrument.
摘要翻译：公开了一种麻醉适配器，其适合于在患者通气期间同时将多个装置或器械插入肺中，同时最小化或消除气体泄漏。麻醉适配器在一个实施例中包括尺寸适于接收第一细长器械的第一端口; 尺寸适于接纳第二细长仪器的第二端口; 构造成联接到血管内管的内窥镜管接头，所述内窥镜管配合流体耦合到所述第一和第二端口; 以及软管接头，其配置成联接到通气机软管，所述软管接头流体地联接到所述第一和第二端口。第一端口围绕第一细长器械密封，第二端口围绕第二细长器械密封。

3. 发明申请

US20140058433A1 BRONCHIAL ISOLATION DEVICES FOR PLACEMENT IN SHORT LUMENS 审中-公开
标题翻译：用于短裤放置的BRONCHIAL隔离装置
公开(公告)号：US20140058433A1
公开(公告)日：2014-02-27
申请号：US13767793
申请日：2013-02-14
申请人： Michael Barrett , Antony J. Fields , Michael J. Hendricksen , Ronald R. Hundertmark , John G. McCutcheon , Alan R. Rapacki , Michael Regan , Steve Wallace
发明人： Michael Barrett , Antony J. Fields , Michael J. Hendricksen , Ronald R. Hundertmark , John G. McCutcheon , Alan R. Rapacki , Michael Regan , Steve Wallace
IPC分类号： A61B17/12 , A61F2/04
CPC分类号： A61B17/12168 , A61B17/12022 , A61B17/12036 , A61B17/12104 , A61B17/12172 , A61B2017/1205 , A61F2/04 , A61F2/24 , A61F2002/043
摘要： Methods and devices are adapted for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.
摘要翻译：方法和装置适于调节流入和流出患者肺部区域的流体流动，例如在呼吸过程中实现期望的流体流动到肺部区域，和/或诱导一个或多个肺部区域的塌陷。根据示例性程序，确定的肺部区域被靶向用于治疗。然后将目标肺区域支气管分离，以通过一个或多个将空气送入目标肺部区域的支气管通路来调节进入和/或离开目标肺区域的气流。

4. 发明授权

US08388682B2 Bronchial flow control devices and methods of use 有权
标题翻译：支气管流量控制装置及使用方法
公开(公告)号：US08388682B2
公开(公告)日：2013-03-05
申请号：US12820393
申请日：2010-06-22
申请人： Michael J. Hendricksen , Michael Barrett
发明人： Michael J. Hendricksen , Michael Barrett
IPC分类号： A61F2/20 , A62B9/00
CPC分类号： A61F2/04 , A61B17/12104 , A61B17/12172 , A61B17/12177 , A61F2002/043 , Y10T29/49826
摘要： Disclosed is an assembly for loading a bronchial flow control device into a container, such as into a delivery catheter. The assembly includes a funnel housing and a puller housing that mate with one another. The funnel housing defines a funnel-shaped loading cavity that receives a flow control device and that gradually reduces in size moving in a first direction. The puller housing is removably attached to the funnel housing and is also removably attachable to a bronchial flow control device that can be positioned in the loading cavity. The puller housing pulls the bronchial flow control device in the first direction through the funnel housing to gradually contract the bronchial flow control device into a compressed state of reduced size relative to the expanded size.
摘要翻译：公开了一种用于将支气管流量控制装置装载到诸如输送导管之类的容器中的组件。该组件包括一个漏斗壳体和一个相互配合的拔出器壳体。漏斗壳体限定漏斗形加载腔，其接纳流量控制装置，并逐渐减小尺寸沿第一方向移动。牵引器壳体可移除地附接到漏斗壳体，并且还可移除地附接到能够定位在加载腔中的支气管流量控制装置。牵引器壳体通过漏斗壳体沿着第一方向拉动支气管流量控制装置，以逐渐将支气管流量控制装置收缩成相对于膨胀尺寸减小尺寸的压缩状态。

5. 发明授权

US07771472B2 Bronchial flow control devices and methods of use 有权
标题翻译：支气管流量控制装置及使用方法
公开(公告)号：US07771472B2
公开(公告)日：2010-08-10
申请号：US11282940
申请日：2005-11-18
申请人： Michael J. Hendricksen , Michael Barrett
发明人： Michael J. Hendricksen , Michael Barrett
IPC分类号： A61F2/20
CPC分类号： A61F2/04 , A61B17/12104 , A61B17/12172 , A61B17/12177 , A61F2002/043 , Y10T29/49826
摘要： Disclosed is an assembly for loading a bronchial flow control device into a container, such as into a delivery catheter. The assembly includes a funnel housing and a puller housing that mate with one another. The funnel housing defines a funnel-shaped loading cavity that receives a flow control device and that gradually reduces in size moving in a first direction. The puller housing is removably attached to the funnel housing and is also removably attachable to a bronchial flow control device that can be positioned in the loading cavity. The puller housing pulls the bronchial flow control device in the first direction through the funnel housing to gradually contract the bronchial flow control device into a compressed state of reduced size relative to the expanded state.
摘要翻译：公开了一种用于将支气管流量控制装置装载到诸如输送导管之类的容器中的组件。该组件包括一个漏斗壳体和一个相互配合的拔出器壳体。漏斗壳体限定漏斗形加载腔，其接纳流量控制装置，并逐渐减小尺寸沿第一方向移动。牵引器壳体可移除地附接到漏斗壳体，并且还可移除地附接到能够定位在加载腔中的支气管流量控制装置。牵引器壳体通过漏斗壳体沿第一方向拉动支气管流量控制装置，以逐渐将支气管流量控制装置收缩成相对于膨胀状态减小尺寸的压缩状态。

6. 发明授权

US08277830B2 Posterior segment drug delivery 有权
公开(公告)号：US08277830B2
公开(公告)日：2012-10-02
申请号：US13252998
申请日：2011-10-04
申请人： Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
发明人： Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
IPC分类号： A61M37/00 , A61M31/00
CPC分类号： G01N33/558 , A61F9/0017 , A61K9/0048 , A61K9/0051 , A61K31/57 , A61K31/573 , A61K31/58 , A61K38/385 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2039/505 , C07K16/22 , C07K2317/24 , C07K2317/55 , Y10T29/49826
摘要： A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.

7. 发明授权

US07837696B2 Articulating suturing device and method 有权
标题翻译：铰接缝合装置及方法
公开(公告)号：US07837696B2
公开(公告)日：2010-11-23
申请号：US10729541
申请日：2003-12-05
申请人： D. Bruce Modesitt , Michael Zung , Michael Barrett , Bernard H. Andreas , Lewis Isbell
发明人： D. Bruce Modesitt , Michael Zung , Michael Barrett , Bernard H. Andreas , Lewis Isbell
IPC分类号： A61B17/04
CPC分类号： A61B17/0625 , A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00672 , A61B2017/047 , A61B2017/0472 , A61B2017/0477 , A61B2017/0496 , A61B2017/06057 , A61B2017/2927
摘要： Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture. The articulating foot may be realigned with the shaft and withdrawn proximally through the tissue tract without dilating the tissue tract.
摘要翻译：用于缝合体腔的装置，系统和方法允许缝合位于经皮组织道远端的血管穿刺部位。在轴的远端附近的细长的铰接脚插入穿过并被致动，使得脚沿着内腔轴线延伸。脚承载缝合附着袖口，并且针从轴穿过穿透外部的血管壁前进，并且在足部被近端拉到血管的内皮表面之后与针箍接合。当针在离开轴时横向偏转针，组织道内的轴的横截面可以被最小化，而脚内的锥形凹陷可以引导前进的针与袖口接合。袖口锁定地接合针，并且可以沿着针路径并通过组织管向近端撤回，以便在穿刺部分上形成缝合线。关节脚可以与轴重新对准并且在组织管道的近侧退回，而不会扩张组织管道。

8. 发明授权

US07445626B2 Device and method for suturing tissue 失效
标题翻译：用于缝合组织的装置和方法
公开(公告)号：US07445626B2
公开(公告)日：2008-11-04
申请号：US10737668
申请日：2003-12-16
申请人： Ronald W. Songer , James W. Vetter , Enrique J. Klein , Bernard A. Andreas , Michael Barrett , Mark J. Foley , Brian Gore , Lewis Isbell , T. Daniel Gross , Tomoaki Hinohara
发明人： Ronald W. Songer , James W. Vetter , Enrique J. Klein , Bernard A. Andreas , Michael Barrett , Mark J. Foley , Brian Gore , Lewis Isbell , T. Daniel Gross , Tomoaki Hinohara
IPC分类号： A61B17/06
CPC分类号： A61B17/11 , A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/06066 , A61B17/3417 , A61B17/3421 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0496 , A61B2017/06057 , A61F2002/30093 , A61F2210/0019
摘要： Systems for suturing a tissue layer having two sides with a suture be releasably retaining at least a portion of the suture in a stationary position on one side of the tissue layer. The portion of the suture is retrieved through the tissue layer from the opposite side whereby the suture is drawn from one side to the opposite side. Systems for suturing the wall of a tubular graft having two sides is also provided using a suture by releasably retaining at least a portion of the suture on one side of the wall. the portion of the length of suture is retrieved through the wall of the graft to the opposite side of the wall.
摘要翻译：通过可靠地将至少一部分缝合线保持在组织层的一侧上的静止位置来提供用于用缝合线缝合具有两侧的组织层的系统。缝线的部分从相对侧通过组织层回收，由此将缝合线从一侧拉到相对侧。也可以使用缝合线通过可释放地将缝合线的至少一部分保持在壁的一侧上来缝合具有两侧的管状移植物的壁的系统。缝合长度的一部分通过移植物的壁回收到壁的相对侧。

9. 发明授权

US07431207B1 System and method for two-step payment transaction authorizations 有权
标题翻译：用于两步付款交易授权的系统和方法
公开(公告)号：US07431207B1
公开(公告)日：2008-10-07
申请号：US11031111
申请日：2005-01-05
申请人： Trey Neemann , Fred Bishop , Michael Barrett , David Armes
发明人： Trey Neemann , Fred Bishop , Michael Barrett , David Armes
IPC分类号： G06K5/00
CPC分类号： G06Q20/40 , G06Q20/10 , G06Q20/385 , G06Q30/0603
摘要： To process a commercial transaction, a merchant receives a card payment request from a customer. The merchant redirects the customer to the card issuer. The authorization computer of the card issuer communicates with the customer and authenticates the identity of the customer as the true cardholder of the card presented for payment. In a first embodiment, the merchant submits an authorization request in response to a card payment request to the authorization computer. The merchant receives an authorization confirmation from the authorization computer upon authentication of the identity of the cardholder. In a second embodiment, the customer receives an authorization confirmation from the authorization computer upon the authentication of the identity of the cardholder. The customer then submits the authorization confirmation to the merchant. The merchant, in turn, confirms the authorization confirmation with the authorization computer.
摘要翻译：为了处理商业交易，商家从客户接收卡付款请求。商家将客户重定向到发卡机构。发卡机构的授权计算机与客户进行通信，并将客户的身份认证为提供付款卡的真实持卡人。在第一实施例中，商家向授权计算机提交响应于卡支付请求的授权请求。验证持卡人的身份后，商家将从授权计算机收到授权确认。在第二实施例中，客户在认证持卡人的身份时从授权计算机接收授权确认。客户然后向商家提交授权确认。反过来，商家确认授权计算机的授权确认。

10. 发明申请

US20070238105A1 High resolution chromosomal mapping 有权
标题翻译：高分辨率染色体定位
公开(公告)号：US20070238105A1
公开(公告)日：2007-10-11
申请号：US11400481
申请日：2006-04-07
申请人： Michael Barrett , Michael Caren
发明人： Michael Barrett , Michael Caren
IPC分类号： C12Q1/68 , C12P19/34 , C12M3/00
CPC分类号： C12Q1/6841
摘要： The present invention generally relates to spatial and structural genomic analysis compositions, which can be used for the mapping of chromosomes and structural analyses of chromosomal rearrangements, including the entire chromosome, as well as specific portions or regions of interest of the chromosomes. In some embodiments, multiple portions of the genome can be distinguished, for instance, using a first detection entity and a second detection entity different from the first detection entity. The detection entities may be immobilized relative to oligonucleotides, which may be selected to bind to different locations within the chromosome. For instance, the oligonucleotides may be at least substantially complementary to the chromosome, e.g., substantially complementary to a specific location of the chromosome.
摘要翻译：本发明一般涉及空间和结构基因组分析组合物，其可以用于染色体的定位和染色体重排的结构分析，包括整个染色体以及染色体感兴趣的具体部分或区域。在一些实施例中，可以区分基因组的多个部分，例如使用不同于第一检测实体的第一检测实体和第二检测实体。检测实体可以相对于寡核苷酸被固定，寡核苷酸可被选择以结合染色体内的不同位置。例如，寡核苷酸可以至少基本上与染色体互补，例如与染色体的特定位置基本互补。

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