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1. 发明公开

US20240047187A1 NEBULISER OUTLET 审中-公开
公开(公告)号：US20240047187A1
公开(公告)日：2024-02-08
申请号：US18489510
申请日：2023-10-18
申请人： Micromass UK Limited
发明人： Ian Trivett , Anthony Hesse , Mark Walford , Daniel J. Kenny , David Gordon , Stanislaw Koziol , Steve D. Trudeau , Alastair M. Booth , Stephen Ayrton
IPC分类号： H01J49/04 , H01J49/16
CPC分类号： H01J49/045 , H01J49/167 , B33Y80/00
摘要： A nebuliser outlet comprises an inlet end and an outlet end, a first channel and one or more second channels arranged between the inlet end and the outlet end. The first channel is configured to receive a capillary, and the one or more second channels are configured to pass gas to the outlet end. The nebuliser outlet is a single integrated component.

2. 发明授权

US11049708B2 Collision surface for improved ionisation 有权
公开(公告)号：US11049708B2
公开(公告)日：2021-06-29
申请号：US16862039
申请日：2020-04-29
申请人： Micromass UK Limited
发明人： Tamas Karancsi , Daniel Simon , Lajos Godorhazy , Daniel Szalay , Steven Derek Pringle , Emrys Jones , Ian Trivett , Stephen O'Brien , Anthony Hesse , Matt Henderson , Alvin Chua , Zoltan Takáts
IPC分类号： H01J49/00 , H01J49/04 , A61B10/02 , A61B17/32 , G01N3/00 , G01N9/00 , G01N33/68 , H01J49/06 , H01J49/16 , A61B5/00 , G01N27/626 , G16H20/00 , G16H10/40 , G16H50/20 , A61B1/273 , A61B5/0507 , A61B10/00 , A61B18/04 , A61B18/18 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N27/622 , G01N27/624 , G01N30/72 , A61B5/145 , A61B18/00
摘要： An apparatus for performing ambient ionisation mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil-shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapour onto said collision assembly.

3. 发明授权

US10438786B2 Probe assembly connector 有权
公开(公告)号：US10438786B2
公开(公告)日：2019-10-08
申请号：US15465070
申请日：2017-03-21
申请人： Micromass UK Limited
发明人： Ian Trivett , Stephen O'Brien , David Gordon
IPC分类号： F16L15/08 , G01N30/72 , H01J49/04 , G01N27/62
摘要： An attachment device for releasably attaching a fluid line to a fluid inlet or outlet is disclosed. The device comprises an attachment member for releasably engaging a fluid inlet or outlet, and an elastic member coupled to the attachment member. The attachment device is attachable to a fluid line such that the attachment member is moveable relative to the fluid line and such that movement of the attachment member relative to the fluid line causes elastic deformation of the elastic member.

4. 发明申请

US20160230889A1 Chamber Seal for Mass Spectrometer 审中-公开
标题翻译：质谱仪舱密封
公开(公告)号：US20160230889A1
公开(公告)日：2016-08-11
申请号：US15023053
申请日：2014-09-17
申请人： MICROMASS UK LIMITED
发明人： Stephen O'Brien , Ian Trivett
IPC分类号： F16J15/02 , H01J49/24 , H01J49/26
CPC分类号： F16J15/025 , H01J49/24 , H01J49/26
摘要： A mass spectrometer is disclosed comprising a first component, an annular vacuum chamber seal and a second component. The first component has a groove. The annular vacuum chamber seal comprises a main body portion and one or more blade or rib portions which protrude from the main body portion. The main body portion is located in the groove and the one or more blade or rib portions protrude above or beyond a surface of the first component. The second component is slid, in use, along the surface of the first component thereby deforming the one or more blade or rib portions so that the one or more blade or rib portions form a radial, diametric or piston seal between the first and second components.
摘要翻译：公开了一种质谱仪，其包括第一部件，环形真空室密封件和第二部件。第一个组件有一个凹槽。环形真空室密封件包括主体部分和从主体部分突出的一个或多个刀片或肋部分。主体部分位于槽中，并且一个或多个刀片或肋部突出在第一部件的表面之上或之上。第二部件在使用中沿着第一部件的表面滑动，从而使一个或多个刀片或肋部分变形，使得一个或多个刀片或肋部分在第一和第二部件之间形成径向，直径或活塞密封。

5. 发明公开

US20240136169A1 ION SOURCE NEBULISER 审中-公开
公开(公告)号：US20240136169A1
公开(公告)日：2024-04-25
申请号：US18546528
申请日：2022-02-15
申请人： Micromass UK Limited
发明人： Alastair Booth , Ian Trivett , Anthony Hesse , Mark Walford , David Gordon , Haydn Murray , Stephen Aryton
IPC分类号： H01J49/04 , H01J49/16
CPC分类号： H01J49/045 , H01J49/0404 , H01J49/167
摘要： A nebuliser comprises an outlet aperture and a liquid capillary. A method of operating the nebuliser comprises supplying a gas to the outlet aperture, measuring a flow rate of the gas supplied to the outlet aperture, and determining a position of the liquid capillary relative to the outlet aperture based on the measured flow rate.

6. 发明授权

US11621154B2 Bench-top time of flight mass spectrometer 有权
公开(公告)号：US11621154B2
公开(公告)日：2023-04-04
申请号：US17057004
申请日：2019-05-31
申请人： Micromass UK Limited
发明人： Ruth Wamsley , Michael Wilson , Ian Trivett , Peter Carney , Haydn Murray , Paul McIver
IPC分类号： H01J49/04 , H01J49/00 , H01J49/06 , H01J49/24 , H01J49/40
摘要： A mass spectrometer comprising: a vacuum chamber; and an ion inlet assembly for transmitting analyte ions into the vacuum chamber; wherein the spectrometer is configured to operate in a cooling mode in which it selectively controls one or more gas flow to the ion inlet assembly for actively cooling the ion inlet assembly.

7. 发明申请

US20180226239A1 PROBE ADAPTOR ASSEMBLY 审中-公开
公开(公告)号：US20180226239A1
公开(公告)日：2018-08-09
申请号：US15947609
申请日：2018-04-06
申请人： Micromass UK Limited
发明人： Ian Trivett , Stephen O'Brien , Graeme Dutton
IPC分类号： H01J49/04 , G01N30/72
CPC分类号： H01J49/0404 , F16L15/08 , G01N27/622 , G01N30/7233 , G01N30/7266 , H01J49/0422
摘要： An apparatus for connecting an ionisation probe assembly to a mass and/or ion mobility spectrometer is disclosed. The apparatus comprises: an attachment member for releasably attaching a probe assembly to the apparatus; a cap for enclosing the attachment member; wherein the apparatus is operable to deliver a voltage to a probe assembly only when the cap is arranged to enclose the attachment member; and wherein the cap is configurable to enclose the attachment member when a probe assembly is attached to the apparatus.

8. 发明授权

US09947522B2 Probe adaptor assembly 有权
公开(公告)号：US09947522B2
公开(公告)日：2018-04-17
申请号：US15464924
申请日：2017-03-21
申请人： Micromass UK Limited
发明人： Ian Trivett , Stephen O'Brien , Graeme Dutton
IPC分类号： H01J49/00 , H01J49/04 , G01N30/72
CPC分类号： H01J49/0404 , F16L15/08 , G01N27/622 , G01N30/7233 , G01N30/7266 , H01J49/0422
摘要： An apparatus for connecting an ionisation probe assembly to a mass and/or ion mobility spectrometer is disclosed. The apparatus comprises: an attachment member for releasably attaching a probe assembly to the apparatus; a cap for enclosing the attachment member; wherein the apparatus is operable to deliver a voltage to a probe assembly only when the cap is arranged to enclose the attachment member; and wherein the cap is configurable to enclose the attachment member when a probe assembly is attached to the apparatus.

9. 发明授权

US09734999B2 Gasket seal for a mass spectrometer 有权
公开(公告)号：US09734999B2
公开(公告)日：2017-08-15
申请号：US15022691
申请日：2014-09-17
申请人： Micromass UK Limited
发明人： Stephen O'Brien , Ian Trivett
IPC分类号： H01J49/26 , H01J49/24 , F16J15/06 , H01J49/00
CPC分类号： H01J49/24 , F16J15/061 , H01J49/0027
摘要： A gasket seal for a mass spectrometer is disclosed. The gasket seal comprises a membrane having an outer profile and an inner profile and one or more protrusions. One or more ports are provided in the body of the membrane. In use a gas or fluid is supplied through at least one of the one or more ports via at least one of the one or more protrusions.

10. 发明公开

US20240194471A1 NEBULISER OUTLET 审中-公开
公开(公告)号：US20240194471A1
公开(公告)日：2024-06-13
申请号：US18556409
申请日：2022-04-21
申请人： Micromass UK Limited
发明人： Ian Trivett , Mark Walford , Daniel James Kenny , Stevan Bajic , Suloke Mathai
IPC分类号： H01J49/16 , H01J49/04
CPC分类号： H01J49/167 , H01J49/045
摘要： A nebuliser outlet (20) comprises one or more first channels (24), wherein the nebuliser outlet (20) is configured such that liquid received by the nebuliser outlet (20) can pass to one or more nebulisation regions via the one or more first channels (24), and one or more second channels (25), wherein the nebuliser outlet (20) is configured such that gas received by the nebuliser outlet (20) can pass to the one or more nebulisation regions via the one or more second channels (25). The one or more first channels (24) comprise a first portion (24a) and a second portion (24b), wherein the first portion (24a) comprises a tubular channel, and wherein the second portion (24b) comprises multiple channels, an annular channel, or a segmented annular channel. The one or more second channels (25) converge with the second portion (24b) at the one or more nebulisation regions.

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