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1. 发明授权

US08158061B2 Automated slide staining apparatus 有权
标题翻译：自动幻灯片染色装置
公开(公告)号：US08158061B2
公开(公告)日：2012-04-17
申请号：US12331838
申请日：2008-12-10
申请人： Preyas Shah , Leonard C. Wagner
发明人： Preyas Shah , Leonard C. Wagner
IPC分类号： G01N21/00
CPC分类号： G01N1/312 , Y10T436/11 , Y10T436/112499 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831
摘要： A slide stainer assembly is disclosed. The slide stainer includes a slide carrier that is configured to carry one or more laboratory slides and a plurality of slide processing stations for processing the slides. A transport member including a plurality of engagement portions is configured for releasably engaging the slide carrier. A drive mechanism is coupled to the transport member. The drive mechanism is configured to move the transport member in a cyclical path such that, in the course of one cycle, the transport member engages a slide carrier docked in a first station, removes the slide carrier from the first station, docks the slide carrier in a second station and returns to the first station to engage another slide carrier.
摘要翻译：公开了一种滑动染色机组件。滑动染色机包括滑动载体，其构造成承载一个或多个实验室滑块和用于处理载玻片的多个滑动处理站。包括多个接合部分的传送构件构造成用于可释放地接合滑动载体。驱动机构联接到传送构件。所述驱动机构构造成沿循环路径移动所述输送构件，使得在一个循环的过程中，所述输送构件接合对接在第一站中的滑动载架，从所述第一站移除所述滑动载架，将所述滑动载体在第二站中并返回到第一站以接合另一个滑架。

2. 发明申请

US20060083623A1 Compression pump system 审中-公开
标题翻译：压缩泵系统
公开(公告)号：US20060083623A1
公开(公告)日：2006-04-20
申请号：US11247363
申请日：2005-10-11
申请人： Mark Higgins , Preyas Shah
发明人： Mark Higgins , Preyas Shah
IPC分类号： F04B49/06
CPC分类号： F04B49/022 , A61H9/0078 , F04B49/065 , F04B2207/043
摘要： According to one embodiment, an apparatus is disclosed that includes a compressor pump and a duty cycle controller. The duty cycle controller controls amount of time that the compressor pump is on each duty cycle. The amount of time is selected so that the compressor pump will operate at a pressure above a desired fill pressure. The operational pressure will generate a restrictive pressure having limited effect on accuracy of pressure reading. Other embodiments are disclosed herein.
摘要翻译：根据一个实施例，公开了一种包括压缩机泵和占空比控制器的装置。占空比控制器控制压缩机泵在每个占空比上的时间量。选择时间量使得压缩机泵将在高于期望的填充压力的压力下操作。操作压力将产生对压力读数精度影响有限的限制压力。本文公开了其它实施例。

3. 发明授权

US08945662B2 Rotary slide stainer 有权
标题翻译：旋转式染色机
公开(公告)号：US08945662B2
公开(公告)日：2015-02-03
申请号：US13605081
申请日：2012-09-06
申请人： Preyas Shah
发明人： Preyas Shah
IPC分类号： B05C3/02 , B05D5/00 , G01N1/30 , B01L9/00
CPC分类号： G01N1/30 , B01L9/52 , G01N1/312 , Y10T436/112499 , Y10T436/113332
摘要： A slide stainer and a method for operating the slide carrier is disclosed. The slide stainer includes a slide carrier that carries one or more laboratory slides; a vessel that is capable of carrying fluid for staining the laboratory slides and that is sized to accommodate the laboratory slides; a slide transporter that moves the slide carrier into and out of the vessel; and a spring loaded pin that engages with a surface of the slide stainer to limit free-fall translation of the slide carrier in an event of a power loss. Additionally, during an agitation phase of a slide staining process, the slide transporter is configured to translate the slide carrier in an upward direction to a pre-determined height that is set by a user of the slide stainer, and the slide transporter translates the slide carrier in a downward direction back into the vessel.
摘要翻译：公开了一种滑动染色机及其操作方法。载玻片染色机包括载有一个或多个实验室载玻片的载玻片; 能容纳染色实验室载片的流体并容纳实验室载玻片的容器; 将滑动载体移入和移出容器的载玻片运送器; 以及弹簧加载的销，其与滑动染色器的表面接合以限制在电力损失的情况下滑动载体的自由落体平移。另外，在滑动染色过程的搅动阶段期间，滑动运送器构造成将滑动载体向上移动到由滑动染色器的使用者设置的预定高度，并且滑块传送器将滑块载体向下返回到容器中。

4. 发明授权

US09200990B2 Tissue processor 有权
公开(公告)号：US09200990B2
公开(公告)日：2015-12-01
申请号：US13323134
申请日：2011-12-12
申请人： Preyas Shah
发明人： Preyas Shah
IPC分类号： A61B10/00 , G01N1/30 , G01N1/31 , A01N1/02 , G01N35/00 , G01N35/02
CPC分类号： G01N1/30 , A01N1/0242 , G01N1/312 , G01N35/00732 , G01N35/0092 , G01N35/025
摘要： A tissue processing system includes a plurality of processing stations. Each processing station includes a plurality of tissue receiving areas that are each configured to accommodate a tissue sample as well as physically isolate that tissue sample from other tissue samples at other receiving areas of the same processing station. Each processing station is configured to separately and individually process the tissue sample at each receiving area to either reduce or eliminate any potential for cross-contamination between the tissue samples undergoing processing at the same processing station. For each receiving area of each processing station, the system is configured to immerse a tissue sample at a particular receiving area in processing fluid for a pre-determined time according to a pre-defined protocol that is based upon parameters of that tissue sample.

5. 发明申请

US20140065291A1 ROTARY SLIDE STAINER 有权
标题翻译：旋转滑块
公开(公告)号：US20140065291A1
公开(公告)日：2014-03-06
申请号：US13605081
申请日：2012-09-06
申请人： Preyas Shah
发明人： Preyas Shah
IPC分类号： B05C3/02 , B05D5/00
CPC分类号： G01N1/30 , B01L9/52 , G01N1/312 , Y10T436/112499 , Y10T436/113332
摘要： A slide stainer and a method for operating the slide carrier is disclosed. The slide stainer includes a slide carrier that carries one or more laboratory slides; a vessel that is capable of carrying fluid for staining the laboratory slides and that is sized to accommodate the laboratory slides; a slide transporter that moves the slide carrier into and out of the vessel; and a spring loaded pin that engages with a surface of the slide stainer to limit free-fall translation of the slide carrier in an event of a power loss. Additionally, during an agitation phase of a slide staining process, the slide transporter is configured to translate the slide carrier in an upward direction to a pre-determined height that is set by a user of the slide stainer, and the slide transporter translates the slide carrier in a downward direction back into the vessel.
摘要翻译：公开了一种滑动染色机及其操作方法。载玻片染色机包括载有一个或多个实验室载玻片的载玻片; 能容纳染色实验室载片的流体并容纳实验室载玻片的容器; 将滑动载体移入和移出容器的载玻片运送器; 以及弹簧加载的销，其与滑动染色器的表面接合以限制在电力损失的情况下滑动载体的自由落体平移。另外，在滑动染色过程的搅动阶段期间，滑动运送器构造成将滑动载体向上移动到由滑动染色器的使用者设置的预定高度，并且滑块传送器将滑块载体向下返回到容器中。

6. 发明申请

US20120310401A1 ROTARY TISSUE PROCESSOR WITH CONFIGURABLE STATIONS 有权
标题翻译：带配置台的旋转组织处理器
公开(公告)号：US20120310401A1
公开(公告)日：2012-12-06
申请号：US13152387
申请日：2011-06-03
申请人： Preyas Shah
发明人： Preyas Shah
IPC分类号： G06F19/00
CPC分类号： G01N1/312 , G01N35/04 , G01N2035/0441
摘要： A configurable tissue processing system is disclosed that includes a plurality of configurable tissue processing stations, each station configured to receive tissue samples and selectively configurable to heat, agitate and apply either a positive pressure or a vacuum pressure to the received tissue samples; a transport mechanism that is configured to transport the tissue samples between the plurality of configurable tissue processing stations; and a control unit coupled to the plurality of configurable tissue processing stations and to the transport mechanism, the control unit controlling the transport mechanism to selectively position the tissue samples in the plurality of configurable tissue processing stations, and the control unit configuring each of the plurality of configurable tissue processing stations to heat, agitate and apply either a positive pressure or a vacuum pressure to the received samples. Also disclosed is a method of configuring the plurality of tissue processing stations.
摘要翻译：公开了一种可配置的组织处理系统，其包括多个可配置的组织处理站，每个站被配置为接收组织样本并且选择性地配置为对所接收的组织样本进行加热，搅动和施加正压力或真空压力; 运送机构，其构造成在所述多个可配置组织处理站之间传送所述组织样本; 以及控制单元，其耦合到所述多个可配置组织处理站和所述传送机构，所述控制单元控制所述传送机构以选择性地将所述组织样本定位在所述多个可配置组织处理站中，并且所述控制单元配置所述多个的可配置组织处理站来加热，搅拌并向接收到的样品施加正压或真空压力。还公开了一种配置多个组织处理站的方法。

7. 发明申请

US20120149059A1 TISSUE PROCESSOR 有权
标题翻译：组织加工商
公开(公告)号：US20120149059A1
公开(公告)日：2012-06-14
申请号：US13323134
申请日：2011-12-12
申请人： Preyas Shah
发明人： Preyas Shah
IPC分类号： G01N1/28 , B01L99/00
CPC分类号： G01N1/30 , A01N1/0242 , G01N1/312 , G01N35/00732 , G01N35/0092 , G01N35/025
摘要： A tissue processing system includes a plurality of processing stations. Each processing station includes a plurality of tissue receiving areas that are each configured to accommodate a tissue sample as well as physically isolate that tissue sample from other tissue samples at other receiving areas of the same processing station. Each processing station is configured to separately and individually process the tissue sample at each receiving area to either reduce or eliminate any potential for cross-contamination between the tissue samples undergoing processing at the same processing station. For each receiving area of each processing station, the system is configured to immerse a tissue sample at a particular receiving area in processing fluid for a pre-determined time according to a pre-defined protocol that is based upon parameters of that tissue sample.
摘要翻译：纸巾处理系统包括多个处理站。每个处理站包括多个组织接收区域，每个组织接收区域被配置为容纳组织样本，并且将该组织样本与来自同一处理站的其他接收区域处的其他组织样本物理隔离。每个处理站被配置为在每个接收区域处单独处理组织样本，以减少或消除在同一处理站进行处理的组织样本之间的交叉污染的任何可能性。对于每个处理站的每个接收区域，系统被配置为根据基于该组织样本的参数的预定义协议将组织样本浸入处理流体中的预定时间的处理流体中。

8. 发明申请

US20060188405A1 Methods and apparatus for efficiently using fluids in a slide stainer 有权
标题翻译：用于在滑动染色机中有效利用流体的方法和装置
公开(公告)号：US20060188405A1
公开(公告)日：2006-08-24
申请号：US11062045
申请日：2005-02-18
申请人： Preyas Shah
发明人： Preyas Shah
IPC分类号： B01L3/00
CPC分类号： G01N1/312 , Y10T436/2575
摘要： Apparatus and methods for applying fluid to slides are disclosed. The apparatus includes a partitioned vessel having a cavity and a sub-cavity that receives fluid, a slide carrier that receives at least one slide in an area corresponding to the sub-cavity, and a transport that positions the slide carrier to position the at least one slide at least partially within the sub-cavity of the partitioned vessel. Fluid is applied to the slides by partitioning the vessel to include a sub-cavity, filling the sub-cavity with fluid, and positioning the at least one slide into fluid filled sub-cavity.
摘要翻译：公开了将流体施加到载玻片的装置和方法。该装置包括分隔容器，其具有腔体和接收流体的子腔体，滑动载体，其在与子腔体相对应的区域中容纳至少一个滑块;以及传送装置，其将滑动载体定位至少至少部分地在分隔的容器的子腔内滑动。流体通过分隔容器而被施加到载玻片，以包括子腔，用流体填充子腔，并将至少一个载玻片定位在充满流体的子腔中。

9. 发明授权

US07883667B2 Methods and apparatus for efficiently using fluids in a slide stainer 有权
标题翻译：用于在滑动染色机中有效利用流体的方法和装置
公开(公告)号：US07883667B2
公开(公告)日：2011-02-08
申请号：US11062045
申请日：2005-02-18
申请人： Preyas Shah
发明人： Preyas Shah
IPC分类号： G01N21/00
CPC分类号： G01N1/312 , Y10T436/2575
摘要： Apparatus and methods for applying fluid to slides are disclosed. The apparatus includes a partitioned vessel having a cavity and a sub-cavity that receives fluid, a slide carrier that receives at least one slide in an area corresponding to the sub-cavity, and a transport that positions the slide carrier to position the at least one slide at least partially within the sub-cavity of the partitioned vessel. Fluid is applied to the slides by partitioning the vessel to include a sub-cavity, filling the sub-cavity with fluid, and positioning the at least one slide into fluid filled sub-cavity.
摘要翻译：公开了将流体施加到载玻片的装置和方法。该装置包括分隔容器，其具有腔体和接收流体的子腔体，滑动载体，其在与子腔体相对应的区域中容纳至少一个滑块;以及传送装置，其将滑动载体定位至少至少部分地在分隔的容器的子腔内滑动。流体通过分隔容器而被施加到载玻片，以包括子腔，用流体填充子腔，并将至少一个载玻片定位在充满流体的子腔中。

10. 发明申请

US20050207470A1 Focusing thermometer 审中-公开
标题翻译：聚焦温度计
公开(公告)号：US20050207470A1
公开(公告)日：2005-09-22
申请号：US11043360
申请日：2005-01-26
申请人： Timothy Bennett , Preyas Shah , William Lourie , Marvin Hutt , Richard Harris
发明人： Timothy Bennett , Preyas Shah , William Lourie , Marvin Hutt , Richard Harris
IPC分类号： G01J5/00 , G01J5/04 , G01J5/08
CPC分类号： G01J5/0003 , G01J5/0011 , G01J5/02 , G01J5/021 , G01J5/025 , G01J5/028 , G01J5/04 , G01J5/049 , G01J5/08 , G01J5/0806
摘要： A sensor assembly for measuring temperature at a target location includes a sensor adapted to detect infrared radiation and produce an electrical output. A focusing lens focuses infrared radiation from the target location onto the sensor while substantially preventing infrared radiation from points outside the target location from being detected by the sensor. In a first embodiment, a sensor assembly for a focusing thermometer includes a sensor and a focusing lens. In a second embodiment, a focusing thermometer for measuring temperature at a target location includes a sensor assembly and electronic circuitry that receives electrical output from the sensor assembly and processes the output into a temperature reading. The sensor assembly includes a focusing lens for focusing infrared radiation from the target location onto the sensor while substantially preventing infrared radiation from points outside the target location from being detected by the sensor.
摘要翻译：用于测量目标位置处的温度的传感器组件包括适于检测红外辐射并产生电输出的传感器。聚焦透镜将来自目标位置的红外辐射聚焦到传感器上，同时基本上防止来自目标位置之外的点的红外辐射被传感器检测到。在第一实施例中，用于聚焦温度计的传感器组件包括传感器和聚焦透镜。在第二实施例中，用于测量目标位置处的温度的聚焦温度计包括传感器组件和接收来自传感器组件的电输出并将输出处理为温度读数的电子电路。传感器组件包括用于将来自目标位置的红外辐射聚焦到传感器上的聚焦透镜，同时基本上防止来自目标位置之外的点的红外辐射被传感器检测到。

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