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1. 发明授权

US08315963B2 Automated hierarchical splitting of anatomical trees 有权
标题翻译：解剖树自动分层分裂
公开(公告)号：US08315963B2
公开(公告)日：2012-11-20
申请号：US12304784
申请日：2007-06-11
申请人： Rafael Wiemker , Thomas Buelow , Roland Opfer
发明人： Rafael Wiemker , Thomas Buelow , Roland Opfer
IPC分类号： G06F17/00 , G06N5/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2207/10072 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： A method for splitting a dataset relating to an anatomical tree structure (12) comprises establishing a plurality of seed points (24) within the tree structure; establishing a length of a path (20) along the tree structure from each of the plurality of seed points (24) to each of a plurality of other points (14); establishing a Euclidean distance (26) from each of the plurality of seed points (24) to each of the plurality of other points (14); associating with the seed point (24) a measure representing a likelihood that the seed point is the root point in dependence on the established lengths (20) and distances (26); identifying the root point of the tree structure (12) as the seed point (24) associated with a maximum measure representing the likelihood that the respective seed point is the root point; and establishing the principal bifurcation point (64) in dependence on the root point.
摘要翻译：一种用于分割与解剖树结构（12）相关的数据集的方法包括在所述树结构内建立多个种子点（24）; 沿着所述树结构建立从所述多个种子点（24）中的每一个到多个其它点（14）中的每一个的路径（20）的长度; 将所述多个种子点（24）中的每一个的欧几里德距离（26）建立到所述多个其他点（14）中的每个; 与种子点（24）相关联，该度量表示根据建立的长度（20）和距离（26）种子点是根点的可能性; 将所述树结构（12）的根点识别为与表示各个种子点是根点的可能性的最大量度相关联的种子点（24）; 并根据根点建立主要分岔点（64）。

2. 发明申请

US20100278408A1 VISUALIZATION OF VASCULARIZATION 有权
标题翻译：血液透析可视化
公开(公告)号：US20100278408A1
公开(公告)日：2010-11-04
申请号：US12742157
申请日：2008-11-04
申请人： Rafael Wiemker , Sven Kabus , Thomas Buelow , Roland Opfer
发明人： Rafael Wiemker , Sven Kabus , Thomas Buelow , Roland Opfer
IPC分类号： G06T7/00
CPC分类号： G06T15/08 , A61B5/489 , A61B6/032 , A61B6/12 , A61B6/504 , G06T7/62 , G06T19/00 , G06T2207/10081 , G06T2207/30101 , G06T2210/41
摘要： An apparatus produces image space data (35) indicative of the spatially varying strength of the vascular connections between locations in the image space and a lesion or other feature of interest. The data may be presented by way of a maximum intensity projection (MIP) display in which the brightness of the image represents the strength of the vascular connection.
摘要翻译：装置产生图像空间数据（35），其指示在图像空间中的位置和感兴趣的病变或其他特征之间的血管连接的空间变化的强度。数据可以通过最大强度投影（MIP）显示来呈现，其中图像的亮度表示血管连接的强度。

3. 发明申请

US20100002922A1 APPARATUS AND METHOD FOR INDICATING LIKELY COMPUTER-DETECTED FALSE POSITIVES IN MEDICAL IMAGING DATA 有权
标题翻译：在医学成像数据中显示计算机检测到的假阳性的装置和方法
公开(公告)号：US20100002922A1
公开(公告)日：2010-01-07
申请号：US12519799
申请日：2007-12-14
申请人： Rafael Wiemker , Roland Opfer , Thomas Buelow
发明人： Rafael Wiemker , Roland Opfer , Thomas Buelow
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T2207/30061
摘要： A data structure for use by a computer system (5) for processing medical image data and representing at least one first region of a patient (8) including at least one computer-detected feature of interest is disclosed. The data structure comprises a first computer code that is executable to detect first data representing at least one second region included within a respective first region. At least one said feature of interest in said second region has a significant likelihood of representing a computer-detected false positive. The second computer code is executable to provide second data for enabling at least one said first region to be displayed on a display device, such that at least one said second region is displayed on the display apparatus differently from part of said first region not containing features of interest having a significant likelihood of representing computer-detected false positives.
摘要翻译：公开了一种由计算机系统（5）用于处理医学图像数据并且代表包括至少一个计算机检测到的感兴趣特征的患者（8）的至少一个第一区域的数据结构。数据结构包括第一计算机代码，其可执行以检测表示包括在相应的第一区域内的至少一个第二区域的第一数据。所述第二区域中至少一个所述感兴趣的特征具有表示计算机检测到的假阳性的显着可能性。第二计算机代码可执行以提供第二数据，用于使至少一个所述第一区域能够显示在显示设备上，使得至少一个所述第二区域不显示在所述显示设备上，不同于所述第一区域的不包含特征具有代表计算机检测到的误报的显着可能性。

4. 发明申请

US20090177444A1 AUTOMATED HIERARCHICAL SPLITTING OF ANATOMICAL TREES 有权
标题翻译：解剖学自动分层分割
公开(公告)号：US20090177444A1
公开(公告)日：2009-07-09
申请号：US12304784
申请日：2007-06-11
申请人： Rafael Wiemker , Thomas Buelow , Roland Opfer
发明人： Rafael Wiemker , Thomas Buelow , Roland Opfer
IPC分类号： G06F17/50 , G06F19/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2207/10072 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： A method for splitting a dataset relating to an anatomical tree structure (12) comprises establishing a plurality of seed points (24) within the tree structure; establishing a length of a path (20) along the tree structure from each of the plurality of seed points (24) to each of a plurality of other points (14); establishing a Euclidean distance (26) from each of the plurality of seed points (24) to each of the plurality of other points (14); associating with the seed point (24) a measure representing a likelihood that the seed point is the root point in dependence on the established lengths (20) and distances (26); identifying the root point of the tree structure (12) as the seed point (24) associated with a maximum measure representing the likelihood that the respective seed point is the root point; and establishing the principal bifurcation point (64) in dependence on the root point.
摘要翻译：一种用于分割与解剖树结构（12）相关的数据集的方法包括在所述树结构内建立多个种子点（24）; 沿着所述树结构建立从所述多个种子点（24）中的每一个到多个其它点（14）中的每一个的路径（20）的长度; 将所述多个种子点（24）中的每一个的欧几里德距离（26）建立到所述多个其他点（14）中的每个; 与种子点（24）相关联，该度量表示根据建立的长度（20）和距离（26）种子点是根点的可能性; 将所述树结构（12）的根点识别为与表示各个种子点是根点的可能性的最大量度相关联的种子点（24）; 并根据根点建立主要分岔点（64）。

5. 发明授权

US08787634B2 Apparatus and method for indicating likely computer-detected false positives in medical imaging data 有权
标题翻译：用于在医学成像数据中指示可能的计算机检测到的假阳性的装置和方法
公开(公告)号：US08787634B2
公开(公告)日：2014-07-22
申请号：US12519799
申请日：2007-12-14
申请人： Rafael Wiemker , Roland Opfer , Thomas Buelow
发明人： Rafael Wiemker , Roland Opfer , Thomas Buelow
IPC分类号： G06K9/00 , G06K9/36 , G06K9/46
CPC分类号： G06T7/0012 , G06T2207/30061
摘要： A data structure for use by a computer system for processing medical image data and representing at least one first region of a patient includes at least one computer-detected feature of interest. The data structure includes a first computer code that is executable to detect first data representing at least one second region included within a respective first region. At least one said feature of interest in said second region has a significant likelihood of representing a computer-detected false positive. The second computer code is executable to provide second data for enabling at least one said first region to be displayed on a display device, such that at least one said second region is displayed on the display apparatus differently from part of said first region not containing features of interest having a significant likelihood of representing computer-detected false positives.
摘要翻译：由计算机系统用于处理医学图像数据并且表示患者的至少一个第一区域的数据结构包括至少一个计算机检测到的感兴趣特征。数据结构包括第一计算机代码，其可执行以检测表示包括在相应的第一区域内的至少一个第二区域的第一数据。所述第二区域中至少一个所述感兴趣的特征具有表示计算机检测到的假阳性的显着可能性。第二计算机代码可执行以提供第二数据，用于使至少一个所述第一区域能够显示在显示设备上，使得至少一个所述第二区域不显示在所述显示设备上，不同于所述第一区域的不包含特征具有代表计算机检测到的误报的显着可能性。

6. 发明授权

US08107707B2 Visualizing a vascular structure 有权
标题翻译：可视化血管结构
公开(公告)号：US08107707B2
公开(公告)日：2012-01-31
申请号：US12516670
申请日：2007-11-27
申请人： Rafael Wiemker , Roland Opfer , Thomas Buelow
发明人： Rafael Wiemker , Roland Opfer , Thomas Buelow
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/032 , A61B6/12 , A61B6/481 , A61B6/503 , G06T7/0012 , G06T2207/10081 , G06T2207/30104
摘要： A system (500) for visualizing a vascular structure represented by a three-dimensional angiography dataset is disclosed. Respective voxel values are associated with respective voxels. The dataset represents a vascular structure. The system comprises means (502) for establishing respective filling values; means (504) for identifying respective minimum filling values; means (506) for computing respective deficiency values; and an output (514) for providing a visualization in dependence on the deficiency values. A respective filling value is indicative of an amount of blood flow at the respective position in the vascular structure. A respective minimum filling value is a minimum of the filling values associated with the positions upstream of the respective position. A respective deficiency value is indicative of a difference between the filling value associated with the respective position and the minimum filling value associated with the respective position.
摘要翻译：公开了一种用于可视化由三维血管造影数据集表示的血管结构的系统（500）。各个体素值与相应的体素相关联。数据集表示血管结构。该系统包括用于建立相应填充值的装置（502）用于识别相应的最小填充值的装置（504）; 用于计算各个不足值的装置（506）; 以及用于根据不足值提供可视化的输出（514）。相应的填充值表示血管结构中各个位置处的血流量。相应的最小填充值是与相应位置的上游位置相关联的填充值的最小值。相应的缺陷值表示与各个位置相关联的填充值与与各个位置相关联的最小填充值之间的差异。

7. 发明申请

US20100260392A1 CONSISTENCY METRIC BASED IMAGE REGISTRATION 审中-公开
标题翻译：一致性公制图像注册
公开(公告)号：US20100260392A1
公开(公告)日：2010-10-14
申请号：US12746179
申请日：2008-12-12
申请人： Rafael Wiemker , Sven Kabus , Thomas Buelow , Roland Opfer
发明人： Rafael Wiemker , Sven Kabus , Thomas Buelow , Roland Opfer
IPC分类号： G06T7/00 , G06K9/60
CPC分类号： G06K9/32 , G06F19/321 , G06K2209/05 , G06T7/337 , G06T2207/10081 , G06T2207/30004
摘要： A method includes registering a first sub-portion of a first image with a corresponding second sub-portion of a second image, and registering the second sub-portion of the second image with a corresponding third sub-portion of the first image. The first sub-portion encompasses a first object of interest, and the third sub-portion encompasses a third object of interest. The method further includes reducing a size of the first sub-portion when the first and third objects of interest are substantially similar. The method further includes repeating the steps of registering the first sub-portion, registering the second sub-portion, and reducing the size of the first sub-portion until the first and third objects are not substantially similar.
摘要翻译：一种方法包括：将第一图像的第一子部分与第二图像的对应的第二子部分对齐，并且将第二图像的第二子部分与第一图像的对应的第三子部分进行登记。第一子部分包含第一感兴趣对象，第三子部分包含第三感兴趣对象。所述方法还包括当所述第一和第三感兴趣对象基本相似时减小所述第一子部分的大小。该方法还包括重复登记第一子部分，登记第二子部分以及减小第一子部分的大小，直到第一和第三对象基本不相似的步骤。

8. 发明授权

US08588492B2 Visualization of vascularization 有权
标题翻译：血管化的可视化
公开(公告)号：US08588492B2
公开(公告)日：2013-11-19
申请号：US12742157
申请日：2008-11-04
申请人： Rafael Wiemker , Sven Kabus , Thomas Buelow , Roland Opfer
发明人： Rafael Wiemker , Sven Kabus , Thomas Buelow , Roland Opfer
IPC分类号： G06K9/00 , G06K9/62
CPC分类号： G06T15/08 , A61B5/489 , A61B6/032 , A61B6/12 , A61B6/504 , G06T7/62 , G06T19/00 , G06T2207/10081 , G06T2207/30101 , G06T2210/41
摘要： An apparatus produces image space data (35) indicative of the spatially varying strength of the vascular connections between locations in the image space and a lesion or other feature of interest. The data may be presented by way of a maximum intensity projection (MIP) display in which the brightness of the image represents the strength of the vascular connection.
摘要翻译：装置产生图像空间数据（35），其指示在图像空间中的位置和感兴趣的病变或其他特征之间的血管连接的空间变化的强度。数据可以通过最大强度投影（MIP）显示来呈现，其中图像的亮度表示血管连接的强度。

9. 发明申请

US20100166270A1 METHOD, APPARATUS, GRAPHICAL USER INTERFACE, COMPUTER-READABLE MEDIUM, AND USE FOR QUANTIFICATION OF A STRUCTURE IN AN OBJECT OF AN IMAGE DATASET 审中-公开
标题翻译：方法，装置，图形用户界面，计算机可读介质，以及用于量化图像数据对象中的结构的用途
公开(公告)号：US20100166270A1
公开(公告)日：2010-07-01
申请号：US12376456
申请日：2007-07-30
申请人： Rafael Wiemker , Thomas Buelow , Roland Opfer
发明人： Rafael Wiemker , Thomas Buelow , Roland Opfer
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2200/24 , G06T2207/10072 , G06T2207/20156 , G06T2207/30061
摘要： The present invention describes a way to quantify the trapped-air disease and how to allow efficient user interaction for inspection via a graphical user interface. The results of the invention may also be used for rapid and accurate diagnosis of trapped air disease. An apparatus, graphical user interface, computer-readable medium and use are also provided.
摘要翻译：本发明描述了一种通过图形用户界面来量化被困空气疾病以及如何允许有效的用户交互进行检查的方式。本发明的结果也可用于对被困空气病的快速和准确的诊断。还提供了一种装置，图形用户界面，计算机可读介质和用途。

10. 发明申请

US20100074493A1 VISUALIZING A VASCULAR STRUCTURE 有权
标题翻译：可视化血管结构
公开(公告)号：US20100074493A1
公开(公告)日：2010-03-25
申请号：US12516670
申请日：2007-11-27
申请人： Rafael Wiemker , Roland Opfer , Thomas Buelow
发明人： Rafael Wiemker , Roland Opfer , Thomas Buelow
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/032 , A61B6/12 , A61B6/481 , A61B6/503 , G06T7/0012 , G06T2207/10081 , G06T2207/30104
摘要： A system (500) for visualizing a vascular structure represented by a three-dimensional angiography dataset is disclosed. Respective voxel values are associated with respective voxels. The dataset represents a vascular structure. The system comprises means (502) for establishing respective filling values; means (504) for identifying respective minimum filling values; means (506) for computing respective deficiency values; and an output (514) for providing a visualization in dependence on the deficiency values. A respective filling value is indicative of an amount of blood flow at the respective position in the vascular structure. A respective minimum filling value is a minimum of the filling values associated with the positions upstream of the respective position. A respective deficiency value is indicative of a difference between the filling value associated with the respective position and the minimum filling value associated with the respective position.
摘要翻译：公开了一种用于可视化由三维血管造影数据集表示的血管结构的系统（500）。各个体素值与相应的体素相关联。数据集表示血管结构。该系统包括用于建立相应填充值的装置（502）用于识别相应的最小填充值的装置（504）; 用于计算各个不足值的装置（506）; 以及用于根据不足值提供可视化的输出（514）。相应的填充值表示血管结构中各个位置处的血流量。相应的最小填充值是与相应位置的上游位置相关联的填充值的最小值。相应的缺陷值表示与各个位置相关联的填充值与与各个位置相关联的最小填充值之间的差异。

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