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1. 发明申请

US20080026398A1 NUCLEIC ACID SEQUENCES FOR DETECTING GENETIC MARKERS FOR CANCER IN A BIOLOGICAL SAMPLE 审中-公开
标题翻译：用于检测生物样品中癌症基因标记的核酸序列
公开(公告)号：US20080026398A1
公开(公告)日：2008-01-31
申请号：US11838168
申请日：2007-08-13
申请人： Richard Harvey , Thomas Clark
发明人： Richard Harvey , Thomas Clark
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： Nucleic acid sequences for detecting the presence of nucleic acids, particularly mRNA, encoding human prostate-associated genetic markers encoding prostate-specific antigen (PSA), prostate specific membrane antigen (PSMA) or human kallikrein 2 (hK2) are disclosed. Preferred combinations of nucleic acid sequences amplifying and detecting the prostate-associated genetic markers RNA, used in methods that include amplification of the target sequences and detection of the amplified sequences are disclosed. Methods of detecting the presence of prostate-associated genetic marker nucleic acids, particularly mRNA, in a biological sample of non-prostate origin are disclosed.
摘要翻译：公开了用于检测编码前列腺特异性抗原（PSA），前列腺特异性膜抗原（PSMA）或人激肽释放酶2（hK2）的编码人前列腺相关遗传标记的核酸特别是mRNA的存在的核酸序列。公开了扩增和检测前列腺相关遗传标记RNA的核酸序列的优选组合，其用于包括扩增靶序列和检测扩增序列的方法中。公开了在非前列腺来源的生物样品中检测前列腺相关遗传标记核酸，特别是mRNA的存在的方法。

2. 发明申请

US20050118630A1 Nucleic acid sequences for detecting genetic markers for cancer in a biological sample 有权
标题翻译：用于检测生物样品中癌症遗传标记物的核酸序列
公开(公告)号：US20050118630A1
公开(公告)日：2005-06-02
申请号：US10978145
申请日：2004-10-28
申请人： Richard Harvey , Thomas Clark
发明人： Richard Harvey , Thomas Clark
IPC分类号： C12N15/09 , C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： Nucleic acid sequences for detecting the presence of nucleic acids, particularly mRNA, encoding human prostate-associated genetic markers encoding prostate-specific antigen (PSA), prostate specific membrane antigen (PSMA) or human kallikrein 2 (hK2) are disclosed. Preferred combinations of nucleic acid sequences amplifying and detecting the prostate-associated genetic markers RNA, used in methods that include amplification of the target sequences and detection of the amplified sequences are disclosed. Methods of detecting the presence of prostate-associated genetic marker nucleic acids, particularly mRNA, in a biological sample of non-prostate origin are disclosed.
摘要翻译：公开了用于检测编码前列腺特异性抗原（PSA），前列腺特异性膜抗原（PSMA）或人激肽释放酶2（hK2）的编码人前列腺相关遗传标记的核酸特别是mRNA的存在的核酸序列。公开了扩增和检测前列腺相关遗传标记RNA的核酸序列的优选组合，其用于包括扩增靶序列和检测扩增序列的方法中。公开了在非前列腺来源的生物样品中检测前列腺相关遗传标记核酸，特别是mRNA的存在的方法。

3. 发明申请

US20080016075A1 Mounted Filesystem Integrity Checking and Salvage 有权
标题翻译：安装的文件系统完整性检查和打捞
公开(公告)号：US20080016075A1
公开(公告)日：2008-01-17
申请号：US11776129
申请日：2007-07-11
申请人： James Seeger , Thomas Clark , Andreas Moran , Jason Young
发明人： James Seeger , Thomas Clark , Andreas Moran , Jason Young
IPC分类号： G06F17/30
CPC分类号： G06F17/30067 , Y10S707/99939 , Y10S707/99953
摘要： A method and system for conducting an integrity check of system and user metadata when the metadata is mounted. A filesystem reviewer is embedded within software of a server node. A mutual exclusion lock is obtained on the selected metadata. An automated verification of the locked metadata is conducted while the filesystem is mounted. In addition, an automated salvage of the locked metadata may be conducted while the filesystem is mounted. The verification and/or salvage of the locked metadata can be applied to system, user, and/or a portion of the user metadata.
摘要翻译：一种用于在安装元数据时进行系统和用户元数据的完整性检查的方法和系统。文件系统审阅者嵌入在服务器节点的软件中。在所选元数据上获得互斥锁。在安装文件系统时进行锁定元数据的自动验证。此外，可以在安装文件系统的同时进行锁定元数据的自动抢救。锁定的元数据的验证和/或补救可以应用于系统，用户和/或用户元数据的一部分。

4. 发明申请

US20070185934A1 Restoring a file to its proper storage tier in an information lifecycle management environment 有权
标题翻译：在文件生命周期管理环境中将文件还原到其正确的存储层
公开(公告)号：US20070185934A1
公开(公告)日：2007-08-09
申请号：US11347515
申请日：2006-02-03
申请人： David Cannon , Thomas Clark , Stephen Correl , Toby Marek , James Seeger , David Wolf , Jason Young , Michael Young
发明人： David Cannon , Thomas Clark , Stephen Correl , Toby Marek , James Seeger , David Wolf , Jason Young , Michael Young
IPC分类号： G06F17/30
CPC分类号： G06F11/1448 , G06F11/1451 , G06F11/1458 , G06F11/1469
摘要： A technique for implementing policy-aware backup and restore capability in a tiered storage system. If a data set's contents are backed up from the tiered storage system to a backup storage system, metadata for the data set may also be backed up. Prior to the data set being restored from the backup storage system to the tiered storage system, the backed up metadata is restored and processed to determine a tier among the tiered storage pools to which the data set will be restored.
摘要翻译：一种在分层存储系统中实现策略感知备份和恢复功能的技术。如果数据集的内容从分层存储系统备份到备份存储系统，则还可以备份数据集的元数据。在数据集从备份存储系统恢复到分层存储系统之前，备份的元数据将被还原和处理，以确定数据集将被还原到的分层存储池中的层。

5. 发明申请

US20060129778A1 Apparatus, system, and method for managing storage space allocation 失效
标题翻译：用于管理存储空间分配的装置，系统和方法
公开(公告)号：US20060129778A1
公开(公告)日：2006-06-15
申请号：US11008316
申请日：2004-12-09
申请人： Thomas Clark , Ramakrishna Dwivedula , Roger Raphael , Robert Rees
发明人： Thomas Clark , Ramakrishna Dwivedula , Roger Raphael , Robert Rees
IPC分类号： G06F12/00
CPC分类号： G06F3/0631 , G06F3/0613 , G06F3/067 , H04L67/1097
摘要： An apparatus, system, and method are disclosed for managing storage space allocation. The apparatus includes a recognizing module, a reserving module, and a managing module. The recognizing module recognizes a trigger event at a client of the data storage system. The reserving module reserves logical units of space for data storage. The management module manages the logical units of space at the client. Such an arrangement provides for distributed management of storage space allocation within a storage area network (SAN). Facilitating client management of the logical units of space in this manner may reduce the number of required metadata transactions between the client and a metadata server and may increase performance of the SAN file system. Reducing metadata transactions effectively lowers network overhead, while increasing data throughput.
摘要翻译：公开了一种用于管理存储空间分配的装置，系统和方法。该装置包括识别模块，预留模块和管理模块。识别模块识别在数据存储系统的客户机处的触发事件。预留模块保留数据存储空间的逻辑单位。管理模块管理客户端的逻辑空间单位。这种布置提供了对存储区域网络（SAN）内的存储空间分配的分布式管理。以这种方式促进对逻辑空间的客户端管理可以减少客户端和元数据服务器之间所需的元数据事务的数量，并且可以提高SAN文件系统的性能。减少元数据事务有效降低网络开销，同时提高数据吞吐量。

6. 发明申请

US20050273451A1 Method, system, and program for maintaining a namespace of filesets accessible to clients over a network 有权
标题翻译：用于维护客户端可通过网络访问的文件集名称空间的方法，系统和程序
公开(公告)号：US20050273451A1
公开(公告)日：2005-12-08
申请号：US10851863
申请日：2004-05-20
申请人： Thomas Clark , Jason Young , Stephen Correl , James Seeger
发明人： Thomas Clark , Jason Young , Stephen Correl , James Seeger
IPC分类号： G06F17/30 , G06F7/00
CPC分类号： G06F17/30067 , Y10S707/959 , Y10S707/99931 , Y10S707/99932 , Y10S707/99943
摘要： Provided are a method, system, and program maintaining information on a namespace comprised of filesets shared by clients over a network. Zone information is maintained on at least one zone, wherein each zone associates at least one client system, at least one fileset, and at least one storage pool. For one zone, the associated at least one fileset and at least one storage pool are accessible to the at least one client system. Clients are provided information on filesets included in a namespace, wherein each of a plurality of clients receive information on the at least one fileset associated with the client in the at least one zone including the client.
摘要翻译：提供了一种维护由客户端通过网络共享的文件集构成的命名空间的信息的方法，系统和程序。区域信息被保存在至少一个区域上，其中每个区域将至少一个客户端系统，至少一个文件集和至少一个存储池相关联。对于一个区域，至少一个客户端系统可访问相关联的至少一个文件集和至少一个存储池。客户端被提供关于包括在命名空间中的文件集的信息，其中多个客户端中的每一个在包括客户端的至少一个区域中接收与客户端相关联的至少一个文件集的信息。

7. 发明申请

US20050251522A1 File system architecture requiring no direct access to user data from a metadata manager 失效
标题翻译：文件系统架构不需要直接访问元数据管理器中的用户数据
公开(公告)号：US20050251522A1
公开(公告)日：2005-11-10
申请号：US10840983
申请日：2004-05-07
申请人： Thomas Clark
发明人： Thomas Clark
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F17/30067 , H04L67/1097 , Y10S707/99939
摘要： A system, method and computer program product for implementing a distributed file system architecture requiring no direct access to user data from a metadata manager in a data storage network. Metadata operations requiring user volume access are performed via a proxy on a storage manager server that is a distributed file system client. Management of metadata can be isolated from user data because the metadata manager requires no capability to see the storage for user volumes. This allows for a distributed file management system to support heterogeneous environments without requiring any single point in the system to see all the storage.
摘要翻译：一种用于实现分布式文件系统架构的系统，方法和计算机程序产品，其不需要直接从数据存储网络中的元数据管理器直接访问用户数据。要求用户卷访问的元数据操作通过作为分布式文件系统客户端的存储管理器服务器上的代理执行。元数据的管理可以与用户数据隔离，因为元数据管理器无需查看用户卷的存储空间。这允许分布式文件管理系统支持异构环境，而不需要系统中的任何一个点来查看所有存储。

8. 发明申请

US20050019628A1 Low temperature fuel cell power plant operation 有权
标题翻译：低温燃料电池发电厂运行
公开(公告)号：US20050019628A1
公开(公告)日：2005-01-27
申请号：US10624190
申请日：2003-07-22
申请人： Thomas Clark , Paul Margiott , Albert Grasso , Richard Breault , Leslie Van Dine , Margaret Steinbugler , Edward Bludnicki
发明人： Thomas Clark , Paul Margiott , Albert Grasso , Richard Breault , Leslie Van Dine , Margaret Steinbugler , Edward Bludnicki
IPC分类号： H01M8/04 , H01M8/06
CPC分类号： H01M8/04225 , H01M8/04014 , H01M8/04022 , H01M8/04029 , H01M8/04037 , H01M8/04119 , H01M8/04141 , H01M8/04223 , H01M8/04302 , H01M8/0606 , H01M2250/20 , Y02T90/32
摘要： A fuel cell power plant system includes the ability to operate an enthalpy recovery device even under cold conditions. A bypass arrangement allows for selectively bypassing one or more portions of the enthalpy recovery device under selected conditions. In one example, the enthalpy recovery device is completely bypassed under selected temperature conditions to allow the device to freeze and then later to be used under more favorable temperature conditions. In another example, the enthalpy recovery device is selectively bypassed during a system startup operation. One example includes a heater associated with the enthalpy recovery device. Another example includes preheating oxidant supplied to one portion of the enthalpy recovery device.
摘要翻译：燃料电池发电厂系统包括即使在寒冷条件下操作焓恢复装置的能力。旁路装置允许在选定的条件下选择性地旁路焓回收装置的一个或多个部分。在一个实例中，焓回收装置在选定的温度条件下完全旁路，以使装置冷冻，然后稍后在更有利的温度条件下使用。在另一示例中，在系统启动操作期间有选择地绕过焓恢复装置。一个示例包括与焓恢复装置相关联的加热器。另一个实例包括将提供给焓回收装置的一部分的氧化剂预热。

9. 发明授权

US06404366B1 Photonic analog-to-digital converter utilizing wavelength division multiplexing and distributed optical phase modulation 失效
标题翻译：使用波分复用和分布式光相位调制的光子模数转换器
公开(公告)号：US06404366B1
公开(公告)日：2002-06-11
申请号：US09726616
申请日：2000-12-01
申请人： Thomas Clark , Paul Matthews
发明人： Thomas Clark , Paul Matthews
IPC分类号： H03M100
CPC分类号： H04J14/02 , G02F7/00 , H03M1/44 , H04J14/06
摘要： A new pipeline method and apparatus for photonic analog-to-digital converters (ADCs) utilizing wavelength division multiplexing (WDM) and distributed phase modulation is disclosed. The analog-to-digital conversion is performed within the optical system of the ADC, and thus the optical output is a digital bit pattern. The optical output of this system thus facilitates ADC conversion at much higher speeds than available with conventional electronic ADCs. Phase modulators and polarization-based optics are used to map an input analog waveform into a binary output.
摘要翻译：公开了一种利用波分复用（WDM）和分布相位调制的用于光子模数转换器（ADC）的新的管线方法和装置。在ADC的光学系统内执行模数转换，因此光输出是数字位模式。因此，该系统的光输出便于以比常规电子ADC可用的更高的速度进行ADC转换。相位调制器和基于偏振的光学器件用于将输入模拟波形映射为二进制输出。

10. 外观设计

USD982865S1 Artist's sink liner with flexible drain retention locking ring 有权
公开(公告)号：USD982865S1
公开(公告)日：2023-04-04
申请号：US29835272
申请日：2022-04-18
申请人： Thomas Clark
设计人： Thomas Clark

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