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1. 发明申请

US20080026398A1 NUCLEIC ACID SEQUENCES FOR DETECTING GENETIC MARKERS FOR CANCER IN A BIOLOGICAL SAMPLE 审中-公开
标题翻译：用于检测生物样品中癌症基因标记的核酸序列
公开(公告)号：US20080026398A1
公开(公告)日：2008-01-31
申请号：US11838168
申请日：2007-08-13
申请人： Richard Harvey , Thomas Clark
发明人： Richard Harvey , Thomas Clark
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： Nucleic acid sequences for detecting the presence of nucleic acids, particularly mRNA, encoding human prostate-associated genetic markers encoding prostate-specific antigen (PSA), prostate specific membrane antigen (PSMA) or human kallikrein 2 (hK2) are disclosed. Preferred combinations of nucleic acid sequences amplifying and detecting the prostate-associated genetic markers RNA, used in methods that include amplification of the target sequences and detection of the amplified sequences are disclosed. Methods of detecting the presence of prostate-associated genetic marker nucleic acids, particularly mRNA, in a biological sample of non-prostate origin are disclosed.
摘要翻译：公开了用于检测编码前列腺特异性抗原（PSA），前列腺特异性膜抗原（PSMA）或人激肽释放酶2（hK2）的编码人前列腺相关遗传标记的核酸特别是mRNA的存在的核酸序列。公开了扩增和检测前列腺相关遗传标记RNA的核酸序列的优选组合，其用于包括扩增靶序列和检测扩增序列的方法中。公开了在非前列腺来源的生物样品中检测前列腺相关遗传标记核酸，特别是mRNA的存在的方法。

2. 发明申请

US20050118630A1 Nucleic acid sequences for detecting genetic markers for cancer in a biological sample 有权
标题翻译：用于检测生物样品中癌症遗传标记物的核酸序列
公开(公告)号：US20050118630A1
公开(公告)日：2005-06-02
申请号：US10978145
申请日：2004-10-28
申请人： Richard Harvey , Thomas Clark
发明人： Richard Harvey , Thomas Clark
IPC分类号： C12N15/09 , C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： Nucleic acid sequences for detecting the presence of nucleic acids, particularly mRNA, encoding human prostate-associated genetic markers encoding prostate-specific antigen (PSA), prostate specific membrane antigen (PSMA) or human kallikrein 2 (hK2) are disclosed. Preferred combinations of nucleic acid sequences amplifying and detecting the prostate-associated genetic markers RNA, used in methods that include amplification of the target sequences and detection of the amplified sequences are disclosed. Methods of detecting the presence of prostate-associated genetic marker nucleic acids, particularly mRNA, in a biological sample of non-prostate origin are disclosed.
摘要翻译：公开了用于检测编码前列腺特异性抗原（PSA），前列腺特异性膜抗原（PSMA）或人激肽释放酶2（hK2）的编码人前列腺相关遗传标记的核酸特别是mRNA的存在的核酸序列。公开了扩增和检测前列腺相关遗传标记RNA的核酸序列的优选组合，其用于包括扩增靶序列和检测扩增序列的方法中。公开了在非前列腺来源的生物样品中检测前列腺相关遗传标记核酸，特别是mRNA的存在的方法。

3. 发明申请

US20070106699A1 Method and system for automatic registration of attribute types 审中-公开
标题翻译：自动注册属性类型的方法和系统
公开(公告)号：US20070106699A1
公开(公告)日：2007-05-10
申请号：US11270320
申请日：2005-11-09
申请人： Richard Harvey , Damon Groenveld
发明人： Richard Harvey , Damon Groenveld
IPC分类号： G06F17/30
CPC分类号： H04L29/12132 , H04L29/12009 , H04L61/00 , H04L61/1552
摘要： According to one embodiment, a method of automatically defining attributes in a directory schema during operation includes determining that an attribute not defined in the schema, and in response, creating a new attribute definition.
摘要翻译：根据一个实施例，在操作期间自动定义目录模式中的属性的方法包括确定未在模式中定义的属性，并且作为响应来创建新属性定义。

4. 发明申请

US20060063156A1 Outcome prediction and risk classification in childhood leukemia 审中-公开
公开(公告)号：US20060063156A1
公开(公告)日：2006-03-23
申请号：US10729895
申请日：2003-12-05
申请人： Cheryl Willman , Paul Helman , Robert Veroff , Monica Mosquera-Caro , George Davidson , Shawn Martin , Susan Atlas , Erik Andries , Huining Kang , Jonathan Shuster , Xuefei Wang , Richard Harvey , David Haaland , Jeffrey Potter
发明人： Cheryl Willman , Paul Helman , Robert Veroff , Monica Mosquera-Caro , George Davidson , Shawn Martin , Susan Atlas , Erik Andries , Huining Kang , Jonathan Shuster , Xuefei Wang , Richard Harvey , David Haaland , Jeffrey Potter
IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C12N15/09 , C07K14/705
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/136
摘要： Genes and gene expression profiles useful for predicting outcome, risk classification, cytogenetics and/or etiology in pediatric acute lymphoblastic leukemia (ALL). OPAL1 is a novel gene associated with outcome and, along with other newly identified genes, represent a novel therapeutic targets.

5. 发明申请

US20060020585A1 Web services apparatus and methods 审中-公开
标题翻译： Web服务设备和方法
公开(公告)号：US20060020585A1
公开(公告)日：2006-01-26
申请号：US10932696
申请日：2004-09-02
申请人： Richard Harvey , Timothy Bently
发明人： Richard Harvey , Timothy Bently
IPC分类号： G06F17/30
CPC分类号： G06F9/465 , G06F16/951 , G06F16/958 , G06F2209/462 , G06F2209/463 , H04L63/10
摘要： A method for use in a Web Services system includes providing access to a data repository and providing shadow attributes for use in conducting searches of the data repository.
摘要翻译：在Web服务系统中使用的方法包括提供对数据存储库的访问并提供用于进行数据存储库搜索的影子属性。

6. 发明授权

US5824505A Vectors, transformed cells and process for the preparation of hirudin 失效
标题翻译：载体，转化细胞和水蛭素的制备方法
公开(公告)号：US5824505A
公开(公告)日：1998-10-20
申请号：US500111
申请日：1995-07-10
申请人： Paul Tolstoshev , Richard Harvey , Michael Courtney , Jean-Pierre LeCocq
发明人： Paul Tolstoshev , Richard Harvey , Michael Courtney , Jean-Pierre LeCocq
IPC分类号： A61K35/16 , A61K38/00 , A61M1/36 , C07K14/815 , C07K17/10 , C12N1/20 , C12N15/00 , C12N15/70 , C12P21/02 , C12Q1/56 , C12N1/21 , C12N15/63
CPC分类号： C07K14/815 , C12N15/70 , A61K38/00
摘要： The present invention relates to vectors for cloning, in a host cell, hirudin or an analog of hirudin, characterized in that it comprises the gene for encoding hirudin or an analog of hirudin, and the elements for the expression of this gene in said host cell, said coding gene beginning, after the starting sequence, by an Ile codon and a Thr codon. This invention also relates to the process for the preparation of hirudin or analogs of hirudin as well as the hirudin or anologs of hirudin obtained.
摘要翻译：本发明涉及用于在宿主细胞，水蛭素或水蛭素类似物中克隆的载体，其特征在于其包含用于编码水蛭素或水蛭素类似物的基因，以及用于在所述宿主细胞中表达该基因的元件所述编码基因在开始序列之后由Ile密码子和Thr密码子开始。本发明还涉及水蛭素水蛭素或类似物的制备方法以及获得的水蛭素的水蛭素或阴离子。

7. 发明授权

US4740382A Antibiotic bonded prosthesis and process for producing same 失效
标题翻译：抗生素粘连假体及其制造方法
公开(公告)号：US4740382A
公开(公告)日：1988-04-26
申请号：US633615
申请日：1984-07-23
申请人： Ralph S. Greco , Richard Harvey , Stanley Z. Trooskin
发明人： Ralph S. Greco , Richard Harvey , Stanley Z. Trooskin
IPC分类号： A61L26/00 , A61L27/00 , A61L27/54 , A61F1/00 , A61F1/24
CPC分类号： A61L27/54 , A61L2300/406 , A61L2300/606 , A61L2300/802 , Y10S273/04 , Y10S273/09 , Y10T428/31544
摘要： There is disclosed an improved prosthesis coated, respectively, with a cationic surfactant, an antibiotic compound and treated with an cationic exchange compound, to remove un-antibiotic bound cationic surfactant.
摘要翻译：公开了一种改进的假体，其分别用阳离子表面活性剂，抗生素化合物涂覆并用阳离子交换化合物处理，以去除未抗生素结合的阳离子表面活性剂。

8. 发明授权

US08042522B2 Fuel rail vent system 有权
标题翻译：燃油轨道排气系统
公开(公告)号：US08042522B2
公开(公告)日：2011-10-25
申请号：US12478980
申请日：2009-06-05
申请人： Kyle Achor , Michael Richards , Richard Harvey
发明人： Kyle Achor , Michael Richards , Richard Harvey
IPC分类号： F02M37/20 , F02M37/22
CPC分类号： F02M37/16 , F02B61/045 , F02M37/007 , F02M37/20 , F02M55/002 , F02M55/007
摘要： A fuel rail vent system for evacuating air from a fuel rail includes a first fuel reservoir and a first fuel line extending between the first fuel reservoir and the fuel rail. A fuel pump is configured in fluid communication with the first fuel reservoir to pump liquid fuel from the first fuel reservoir to the fuel rail through the first fuel line. A second fuel line separate from the first fuel line extends between the first fuel reservoir and the fuel rail. A primer system is configured for fluid communication with the first fuel reservoir to pump liquid fuel from the first fuel reservoir to the fuel rail through the second fuel line. A second fuel reservoir separate from the first fuel reservoir is configured for fluid communication with the fuel rail downstream of the fuel rail to receive any excess liquid fuel and/or fuel vapor upstream therefrom.
摘要翻译：用于从燃料轨道排空空气的燃料轨道排气系统包括第一燃料储存器和在第一燃料储存器和燃料轨道之间延伸的第一燃料管线。燃料泵构造成与第一燃料储存器流体连通，以将液体燃料从第一燃料储存器通过第一燃料管线泵送到燃料轨道。与第一燃料管线分离的第二燃料管路在第一燃料储存器和燃料轨道之间延伸。底漆系统被配置为与第一燃料储存器流体连通，以将来自第一燃料储存器的液体燃料通过第二燃料管线输送到燃料轨道。与第一燃料储存器分离的第二燃料储存器被配置为与燃料轨道下游的燃料轨道流体连通，以在其上游接收任何多余的液体燃料和/或燃料蒸汽。

9. 发明申请

US20100102257A1 VAPOR VENT CONTROL APPARATUS, SYSTEM AND OUTBOARD MARINE ENGINE THEREWITH 有权
标题翻译：蒸汽风门控制装置，系统和外部船用发动机
公开(公告)号：US20100102257A1
公开(公告)日：2010-04-29
申请号：US12604538
申请日：2009-10-23
申请人： Kyle D. Achor , Richard Harvey
发明人： Kyle D. Achor , Richard Harvey
IPC分类号： F16K31/08 , F01L3/10 , F16K31/44
CPC分类号： F16K31/084 , F02M25/0836 , F16K1/308 , F16K24/04 , Y10T137/86324
摘要： An outboard marine engine has vapor vent control apparatus including a fuel inlet in fluid communication with a fuel reservoir of the engine. The fuel inlet is operably attachable to a fuel pin of a fuel connector. When attached, liquid fuel flows to the fuel reservoir and when detached, liquid fuel flow out of the fuel inlet is prevented. A vapor vent passage is configured in fluid communication with the liquid fuel reservoir and an air intake of the engine. A vent pin is disposed in the vapor vent passage. The vent pin moves between a first position upon attaching the fuel connector to the fuel inlet and a second position upon detaching the fuel connector from the fuel inlet. In the first position, the vapor vent passage is open to fuel vapor flow and, when in the second position, the vapor vent passage is closed to fuel vapor flow.
摘要翻译：舷外船用发动机具有蒸气排放控制装置，其包括与发动机的燃料箱流体连通的燃料入口。燃料入口可操作地附接到燃料连接器的燃料销。当附接时，液体燃料流到燃料储存器，并且当分离时，液体燃料流出燃料入口被阻止。蒸汽通气通道构造成与液体燃料储存器和发动机的进气口流体连通。排气口设置在蒸气通道中。当将燃料连接器附接到燃料入口时，排气销在第一位置之间移动，并且在将燃料连接器从燃料入口拆卸时，第二位置移动。在第一位置，蒸汽通气通道对燃料蒸汽流开放，并且当处于第二位置时，蒸汽通气通道关闭以燃料蒸气流动。

10. 发明申请

US20070106691A1 System and method for efficient directory performance using non-persistent storage 有权
标题翻译：使用非持久存储的高效目录性能的系统和方法
公开(公告)号：US20070106691A1
公开(公告)日：2007-05-10
申请号：US11269637
申请日：2005-11-09
申请人： Richard Harvey , Benjamin Gardiner
发明人： Richard Harvey , Benjamin Gardiner
IPC分类号： G06F17/00
CPC分类号： G06F17/30008
摘要： A system and method are provided for processing directory service operations. The system includes a client device communicatively coupled to one or more directory servers. Each directory server includes a communications interface, a storage mechanism, and an evaluation module. According to an exemplary embodiment, the storage mechanism is a non-persistent storage mechanism which increases read and write performance. When a directory server receives a directory service operation, it determines whether it is capable of processing the operation, and if so, processes it with respect to its non-persistent storage mechanism.
摘要翻译：提供了一种用于处理目录服务操作的系统和方法。该系统包括通信地耦合到一个或多个目录服务器的客户端设备。每个目录服务器包括通信接口，存储机构和评估模块。根据示例性实施例，存储机制是增加读写性能的非持久存储机制。当目录服务器接收目录服务操作时，它确定它是否能够处理该操作，如果是，则对其非永久存储机制进行处理。

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