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    • 1. 发明授权
    • System and method for placing a medical electrical lead
    • 放置医用电线的系统和方法
    • US06697677B2
    • 2004-02-24
    • US09826730
    • 2001-04-05
    • Roger DahlBrad D. PedersenDuane ZytkoviczKenneth C. Gardeski
    • Roger DahlBrad D. PedersenDuane ZytkoviczKenneth C. Gardeski
    • A61N105
    • A61N1/056A61N2001/0578A61N2001/058A61N2001/0585
    • An improved system and method that is capable of delivering multiple electrode assemblies to predetermined implant sites within a body is disclosed. The system includes an elongated member such as an introducer sheath. The introducer includes an elongated channel along at least a distal end portion of the introducer. The elongated channel opens to the exterior surface of the introducer through an elongated slot. One or more electrode assemblies may be retained within the elongated channel such that the leads exit the introducer via the elongated slot. The elongated introducer further includes a lumen that is in fluid communication with channel through openings, or gaps. The electrode assemblies are loaded within the channel at predetermined positions with respect to the openings. A distal end of a stiffening member such as a stylet may then be advanced within the lumen and through a selected one of the openings to engage an electrode assembly. The distal end of the stylet, along with the electrode assembly, is pushed in a distal direction within the channel until the electrode assembly exits the channel at a predetermined implant site. The stylet is then de-coupled from the electrode assembly, and the distal end is again retracted into the lumen. The distal end of the stiffening member may be re-directed into a different opening to engage a second electrode assembly. After the introducer is repositioned at a second implant site, the second electrode assembly may be deployed in a manner similar to that discussed above. The process may be repeated to deploy an array of electrodes. According to one aspect of the invention, the stylet distal end is canted to extend from the lumen of the introducer into the channel.
    • 公开了能够将多个电极组件递送到体内预定植入部位的改进的系统和方法。 该系统包括细长构件,例如导引器护套。 导引器包括沿导引器的至少远端部分的细长通道。 细长通道通过细长的槽向导引器的外表面开口。 一个或多个电极组件可以保持在细长通道内,使得引线经由细长槽离开导引器。 细长导引器还包括与通道通过开口或间隙流体连通的内腔。 电极组件相对于开口在预定位置处装载在通道内。 然后,诸如探针之类的加强构件的远端可以在内腔内并通过选定的一个开口进入以接合电极组件。 探针的远端与电极组件一起沿通道内的远端方向推动,直到电极组件在预定的植入部位离开通道。 然后将探针从电极组件脱耦合,并且远端再次缩回到内腔中。 加强构件的远端可以被重新引导到不同的开口中以接合第二电极组件。 在导引器在第二植入位置重新定位之后,第二电极组件可以以与上述相似的方式展开。 可以重复该过程以展开电极阵列。 根据本发明的一个方面,探针的远端倾斜以从导引器的内腔延伸到通道中。
    • 2. 发明授权
    • System and method for placing endocardial leads
    • 放置心内膜导管的系统和方法
    • US06934589B2
    • 2005-08-23
    • US09827108
    • 2001-04-05
    • Stephen SundquistArnold ThorntonRoger DahlDuane ZytkoviczKenneth C. Gardeski
    • Stephen SundquistArnold ThorntonRoger DahlDuane ZytkoviczKenneth C. Gardeski
    • A61N1/05A61N1/00
    • A61N1/056A61N2001/0578A61N2001/0585
    • An improved system and method for deploying medical electrical leads is disclosed. The system includes a guiding device such as a guidewire used to navigate the vascular system of a body. The guiding device includes a fixation member that can be deployed to maintain the guiding device at a desired location within the vascular system. The fixation member may be an inflatable device such as a balloon, or alternatively, may be an expandable device constructed of flexible fibers that has both an expanded and a contracted state. The system may further include a coupling member located adjacent to the guiding device. The coupling member may be a rail extending distally from a proximal end of the guiding device to a point proximal the fixation member. In an alternative embodiment of the invention, the coupling member is a channel included in the body of the guiding device adapted to slidably engage an electrode assembly. The coupling member is adapted to allow the electrode assembly to be slid to the distal end of the coupling member and deployed at a predetermined implant site. In one embodiment of the invention, the coupling member is movable with respect to the guiding device. This allows the coupling member to be re-positioned to multiple implant sites to deploy more than one electrode while the fixation mechanism remains stationary within a patient's vascular system. According to yet another aspect of the invention, the guiding device includes a lumen to delivery fluoro visible medium.
    • 公开了用于部署医疗电引线的改进的系统和方法。 该系统包括诸如用于导航身体的血管系统的导丝的引导装置。 引导装置包括可以部署以将引导装置保持在血管系统内的期望位置的固定构件。 固定构件可以是诸如气囊的可充气装置,或者可替代地,可以是由具有膨胀和收缩状态的柔性纤维构成的可扩张装置。 该系统还可以包括邻近引导装置定位的联接构件。 联接构件可以是从引导装置的近端向靠近固定构件的点向远侧延伸的轨道。 在本发明的替代实施例中,联接构件是包括在引导装置的主体中的通道,其适于可滑动地接合电极组件。 联接构件适于允许电极组件滑动到联接构件的远端并且在预定的植入位置展开。 在本发明的一个实施例中,联接构件可相对于引导装置移动。 这允许将联接构件重新定位到多个植入位置以展开多于一个电极,同时固定机构在患者的血管系统内保持静止。 根据本发明的另一方面,引导装置包括用于输送氟可见介质的内腔。
    • 3. 发明授权
    • System for anchoring mid-lead electrode on an endocardial catheter lead
    • 用于在心内膜导管引线上固定中间引线电极的系统
    • US5782898A
    • 1998-07-21
    • US729900
    • 1996-10-15
    • Roger DahlDuane Zytkovicz
    • Roger DahlDuane Zytkovicz
    • A61N1/05
    • A61N1/057
    • A system for passively anchoring mid-lead electrodes on an endocardial catheter lead includes at least one fibrosis-anchoring opening positioned along the exterior surface of the catheter lead body proximal or distal to the mid-lead electrodes for passively securing the catheter lead against the interior wall of the heart. Within the fibrosis-anchoring openings a suitable material is provided for anchoring the catheter lead body to the heart wall by fibrosis. Preferably, the fibrosis-anchoring openings comprise at least a pair of openings positioned only partially around the exterior of the catheter lead body at locations both proximal and distal to the mid-lead electrodes, with the catheter lead body between the fibrosis-anchoring openings being pre-formed to bias the mid-lead electrodes against the heart wall.
    • 用于在心内膜导管引线上被动地固定中间引线电极的系统包括至少一个纤维化锚定开口,沿着导管引线体的外表面位于中间引线电极的近端或远端,用于被动地将导管引线固定在内部 心脏的墙壁 在纤维化锚定开口内,提供合适的材料用于通过纤维化将导管引线体锚固到心脏壁。 优选地,纤维化锚定开口包括至少一对开口,该对开口仅位于导联引线体的外部位于中间引线电极的近端和远端的位置处,导线引线主体位于纤维化锚定开口之间 预先形成以将中间引线电极偏压抵靠心壁。
    • 5. 发明授权
    • Medical electrical lead having an expandable electrode assembly
    • 具有可扩张电极组件的医用电线
    • US06697676B2
    • 2004-02-24
    • US09836015
    • 2001-04-17
    • Roger DahlDuane ZytkoviczStephen SundquistThomas M. Soukup
    • Roger DahlDuane ZytkoviczStephen SundquistThomas M. Soukup
    • A61N104
    • A61N1/056A61N2001/0578
    • An implantable device including an elastically compressible member coupled to a distal end of a lead and further coupled to at least one electrode. The compressible member is in a contracted state when the electrode is being delivered to an implant site. At the implant site, the compressible member is expanded to urge the electrode into contact with tissue. Compressible member further includes a keyed structure to engage a stiffening member such as a stylet. The stiffening member is used both to deliver the electrode to the implant site, and to rotate the compressible member, if necessary, so that the electrode contacts predetermined body tissue. According to one aspect of the invention, an introducer having an inner lumen with a diameter that is smaller than that of the compressible member may be used to disengage the stiffening member from the compressible member. In one embodiment, compressible member includes a conductor wound to form multiple turns that are aligned during electrode delivery, but which expand into a non-aligned configuration after deployment. In another embodiment, compressible member includes a spring clip that has a compressed profile during delivery, and an expanded profile after deployment.
    • 一种可植入装置,其包括耦合到引线的远端并进一步耦合到至少一个电极的弹性可压缩构件。 当电极被输送到植入部位时,可压缩构件处于收缩状态。 在植入位置,可压缩构件被膨胀以促使电极与组织接触。 可压缩构件还包括用于接合诸如探针之类的加强构件的键合结构。 加强构件用于将电极输送到植入位置,并且如果需要,可旋转可压缩构件,使得电极接触预定的身体组织。 根据本发明的一个方面,可以使用具有直径小于可压缩构件直径的内腔的导引器来使加强构件从可压缩构件脱离。 在一个实施例中,可压缩构件包括缠绕以形成多个匝的导体,其在电极传递期间对准,但在展开之后扩展成不对准构造。 在另一个实施例中,可压缩构件包括弹簧夹,其在输送期间具有压缩轮廓,并且在展开之后具有扩展轮廓。
    • 7. 发明授权
    • Bifurcated lead system for a cardiac vein
    • 用于心脏静脉的分叉引导系统
    • US06772015B2
    • 2004-08-03
    • US09820156
    • 2001-03-28
    • Roger DahlElisabeth Lacy Belden
    • Roger DahlElisabeth Lacy Belden
    • A61N105
    • A61N1/056A61N2001/0585
    • A bi-furcated medical electrical lead that is adapted to be implanted in the cardiac venous system is disclosed. The lead includes a bifurcated distal portion having first and second elongated members, or fingers. In one embodiment, the first elongated member, or thumb portion, is adapted to be positioned within the coronary sinus or great cardiac vein. The second elongated member, or finger portion, of the bifurcated distal tip, may be positioned within a branch vessel of the coronary sinus such as the posterior vein or middle cardiac vein. The thumb portion may carry at least one electrode for pacing and/or sensing, and may carry additional electrodes for multi-polar pacing applications, whereas the finger portion may carry a defibrillation electrode. Portions of the pacing/sensing electrodes may be insulated so that electrical stimulation is only delivered to myocardial tissue. According to one method of using the bifurcated lead system, the lead may be employed in conjunction with a standard right ventricular pacing and defibrillation lead to deliver big-ventricular pacing and defibrillation therapy. Both the thumb and finger may include preformed or shapeable distal tips to aid in the positioning of these structures within the respective vessels. A stiffening member may be used to maintain the thumb in a substantially parallel position with the finger when the lead is being positioned within the vascular system, as may be accomplished with the further use of a guide catheter.
    • 公开了一种适于植入心脏静脉系统的双分叉医用电气引线。 引线包括具有第一和第二细长构件或手指的分叉远端部分。 在一个实施例中,第一细长构件或拇指部分适于定位在冠状窦或大心静脉内。 分叉的远侧末端的第二细长构件或手指部分可以位于冠状窦的分支血管内,例如后静脉或中心静脉。 拇指部分可以携带至少一个用于起搏和/或感测的电极,并且可以携带用于多极起搏应用的附加电极,而手指部分可携带除颤电极。 起搏/感测电极的部分可以是绝缘的,使得电刺激仅被递送到心肌组织。 根据使用分叉铅系统的一种方法,铅可以与标准的右心室起搏和除颤导联一起使用以递送大心室起搏和除颤疗法。 拇指和手指可以包括预制的或可成形的远侧末端,以帮助将这些结构定位在相应的容器内。 当引线定位在血管系统内时,加强构件可以用于将拇指保持在与手指基本上平行的位置,如可以通过进一步使用导向导管来实现的。