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1. 发明申请

US20090099266A1 Antifungal nail coat and method of use 审中-公开
标题翻译：抗真菌指甲外套及使用方法
公开(公告)号：US20090099266A1
公开(公告)日：2009-04-16
申请号：US12316009
申请日：2008-12-09
申请人： Stanley W. Kepka , Y. Joseph Mo , Hang-Yong Wang , Mingqi Lu , William R. Pfister
发明人： Stanley W. Kepka , Y. Joseph Mo , Hang-Yong Wang , Mingqi Lu , William R. Pfister
IPC分类号： A01N33/04 , A01P3/00
CPC分类号： A61K31/137 , A61K8/41 , A61K8/44 , A61K9/0014 , A61K9/08 , A61K9/7015 , A61K47/14 , A61K47/32 , A61Q3/02 , Y10S424/808
摘要： Antifungal nail coat compositions containing an allylamine, an N,N-di(C1-C8) alkylamino substituted, (C4-C18) alkyl (C2-C18) carboxylic ester or a pharmaceutically acceptable acid addition salt thereof, a hydrophilic polymer, and a pharmaceutically acceptable, volatile organic carrier are disclosed. The composition provides a substantially water-soluble, fungicidal coating upon contact with a fungally susceptible or infected nail.
摘要翻译：含有烯丙胺，N，N-二（C1-C8）烷基氨基取代的（C4-C18）烷基（C2-C18）羧酸酯或其药学上可接受的酸加成盐的抗真菌指甲油组合物，亲水性聚合物和公开了药学上可接受的挥发性有机载体。当与真菌感染或感染的指甲接触时，组合物提供基本上水溶性的杀真菌涂层。

2. 发明授权

US07462362B2 Antifungal nail coat and method of use 失效
标题翻译：抗真菌指甲外套及使用方法
公开(公告)号：US07462362B2
公开(公告)日：2008-12-09
申请号：US10514190
申请日：2004-03-22
申请人： Stanley W. Kepka , Y. Joseph Mo , Hang-Yong Wang , Mingqi Lu , William R. Pfister
发明人： Stanley W. Kepka , Y. Joseph Mo , Hang-Yong Wang , Mingqi Lu , William R. Pfister
IPC分类号： A61K8/00 , A61K8/18
CPC分类号： A61K31/137 , A61K8/41 , A61K8/44 , A61K9/0014 , A61K9/08 , A61K9/7015 , A61K47/14 , A61K47/32 , A61Q3/02 , Y10S424/808
摘要： A dual action antifungal nail coat composition and method of use for ameliorating or preventing fungal infection of the nails, and onychomycosis, in particular, is disclosed. Composition embodiments in the form of one-coat type and two-coat type suitable for daily fungicidal regimens are disclosed. A preferred antifungal nail coat composition comprises an effective fungicidal amount of antifungal agent, a permeation enhancing amount of a substantially non-volatile, permeation enhancer, a film-forming amount of a hydrophilic polymer, and a pharmaceutically acceptable, volatile carrier. The composition provides a substantially water-soluble fungicidal coating on contacting a fungally susceptible or infected nail.
摘要翻译：公开了一种双作用抗真菌指甲油组合物和用于改善或预防指甲真菌感染和甲真菌病的用途的方法。公开了适用于日常杀真菌方案的单涂层型和双层型形式的组合物实施方案。优选的抗真菌指甲涂层组合物包含有效杀真菌量的抗真菌剂，渗透促进量的基本上不挥发的渗透促进剂，成膜量的亲水性聚合物和药学上可接受的挥发性载体。组合物在接触真菌感染或感染的指甲时提供基本上水溶性的杀真菌涂层。

3. 发明授权

US06974513B2 Cosmetic applicator and method and system for manufacturing the applicator 失效
标题翻译：化妆品涂抹器和用于制造涂布器的方法和系统
公开(公告)号：US06974513B2
公开(公告)日：2005-12-13
申请号：US10383696
申请日：2003-03-06
申请人： Stanley W. Kepka
发明人： Stanley W. Kepka
IPC分类号： A46B3/02 , A46D3/00 , A46D9/00 , B29C41/08
CPC分类号： A46B3/02 , A46B2200/1053 , A46D3/00
摘要： The present invention relates to a method and system of manufacturing a cosmetic applicator in which a predetermined pattern of flocking bristles are dispensed toward the applicator and are adhered to the applicator by an adhesive. The flocking bristles can be dispensed using a flocking dispenser. The flocking dispenser is moveable in a longitudinal direction forward and backward along the sides and tip of the applicator. During or after movement of the flocking dispenser, the applicator can be rotated around its longitudinal axis. The movement of the flocking dispenser and rotation of the applicator can be controlled to provide the desired pattern of flocking bristles. The density of distribution of the flocking bristles can be controlled by varying the speed of movement and rotation of the applicator and the amount of flocking bristles which are dispensed from the flocking dispenser. For example, a high density of flocking bristles can be applied to extend radially from the tip. The flocking bristles can include one or more types of bristles which differ by one or more of material, cross section, shape, length, diameter or composition.
摘要翻译：本发明涉及一种制造化妆品涂抹器的方法和系统，其中将植绒刷毛的预定图案分配给施用器并通过粘合剂粘附到施用器上。可以使用植绒分配器分配植绒刷毛。植绒分配器可沿着纵向方向沿着涂抹器的侧面和尖端向前和向后移动。在植绒分配器移动期间或之后，施用器可围绕其纵向轴线旋转。可以控制植绒分配器的运动和施用器的旋转以提供所需的植绒刷毛图案。可以通过改变涂抹器的移动速度和旋转速度以及从植绒分配器分配的植绒刷毛的量来控制植绒刷毛的分布密度。例如，可以应用高密度的植绒刷毛从尖端径向延伸。植绒刷毛可以包括由材料，截面，形状，长度，直径或组成中的一种或多种所不同的一种或多种类型的刷毛。

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