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1. 发明授权

US08623935B2 Antimicrobial compositions 有权
标题翻译：抗微生物组合物
公开(公告)号：US08623935B2
公开(公告)日：2014-01-07
申请号：US12811184
申请日：2008-12-31
申请人： Terry R. Hobbs , Robert A. Asmus
发明人： Terry R. Hobbs , Robert A. Asmus
IPC分类号： C08K5/00 , C08K5/05
CPC分类号： A01N25/02 , A01N25/10 , A01N47/44 , A01N2300/00
摘要： Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a hydrophobic polymer soluble in the lower alcohol; an emollient ester such as diesters of bibasic acids and triesters of citric acid; and an optional fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.
摘要翻译：提供了抗微生物组合物，其包括含有较低C 2 -C 5醇和水的水醇溶剂体系; 阳离子抗菌剂，如葡萄糖酸洗必太; 可溶于低级醇的疏水性聚合物; 一种软化酯如二元酸二酯和柠檬酸三酯; 和含有至少一个游离羟基的任选的脂肪组分，例如C 12 -C 21脂肪醇，C 12 -C 21脂肪酸酯，C 12 -C 21脂肪醚，C 12 -C 21脂肪酰胺及其组合。本文所述的组合物显示出改进的抗微生物效能和改善的美容优雅。

2. 发明授权

US08338491B2 Antimicrobial compositions 有权
标题翻译：抗微生物组合物
公开(公告)号：US08338491B2
公开(公告)日：2012-12-25
申请号：US12445376
申请日：2007-10-25
申请人： Robert A. Asmus , Terry R. Hobbs
发明人： Robert A. Asmus , Terry R. Hobbs
IPC分类号： A01N33/18 , A61K6/00
CPC分类号： A61K31/155 , A01N31/02 , A01N33/12 , A01N47/44 , A01N25/02 , A01N37/04 , A01N37/36 , A01N2300/00
摘要： Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof; and optionally an emollient ester such as diesters of bibasic acids and triesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.
摘要翻译：提供了抗微生物组合物，其包括含有较低C 2 -C 5醇和水的水醇溶剂体系; 阳离子抗菌剂，如葡萄糖酸洗必太; 含有至少一个游离羟基的脂肪成分，如C12-C21脂肪醇，C12-C21脂肪酸酯，C12-C21脂肪醚，C12-C21脂肪酰胺及其组合; 和任选的软化酯，例如二元酸的二酯和柠檬酸的三酯。本文所述的组合物显示出改进的抗微生物效能和改善的美容优雅。

3. 发明申请

US20100282409A1 ANTIMICROBIAL COMPOSITIONS 有权
标题翻译：抗微生物组合物
公开(公告)号：US20100282409A1
公开(公告)日：2010-11-11
申请号：US12811184
申请日：2008-12-31
申请人： Terry R. Hobbs , Robert A. Asmus
发明人： Terry R. Hobbs , Robert A. Asmus
IPC分类号： B32B37/12 , A61K31/155 , A61K31/14 , A61P31/00
CPC分类号： A01N25/02 , A01N25/10 , A01N47/44 , A01N2300/00
摘要： Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a hydrophobic polymer soluble in the lower alcohol; an emollient ester such as diesters of bibasic acids and triesters of citric acid; and an optional fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.
摘要翻译：提供了抗微生物组合物，其包括含有较低C 2 -C 5醇和水的水醇溶剂体系; 阳离子抗菌剂，如葡萄糖酸洗必太; 可溶于低级醇的疏水性聚合物; 一种软化酯如二元酸二酯和柠檬酸三酯; 和含有至少一个游离羟基的任选的脂肪组分，例如C 12 -C 21脂肪醇，C 12 -C 21脂肪酸酯，C 12 -C 21脂肪醚，C 12 -C 21脂肪酰胺及其组合。本文所述的组合物显示出改进的抗微生物效能和改善的美容优雅。

4. 发明申请

US20100022654A1 ANTIMICROBIAL COMPOSITIONS 有权
标题翻译：抗微生物组合物
公开(公告)号：US20100022654A1
公开(公告)日：2010-01-28
申请号：US12445376
申请日：2007-10-25
申请人： Robert A. Asmus , Terry R. Hobbs
发明人： Robert A. Asmus , Terry R. Hobbs
IPC分类号： A01N37/52
CPC分类号： A61K31/155 , A01N31/02 , A01N33/12 , A01N47/44 , A01N25/02 , A01N37/04 , A01N37/36 , A01N2300/00
摘要： Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof; and optionally an emollient ester such as diesters of bibasic acids and triesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.
摘要翻译：提供了抗微生物组合物，其包括含有较低C 2 -C 5醇和水的水醇溶剂体系; 阳离子抗菌剂，如葡萄糖酸洗必太; 含有至少一个游离羟基的脂肪成分，如C12-C21脂肪醇，C12-C21脂肪酸酯，C12-C21脂肪醚，C12-C21脂肪酰胺及其组合; 和任选的软化酯，例如二元酸的二酯和柠檬酸的三酯。本文所述的组合物显示出改进的抗微生物效能和改善的美容优雅。

5. 发明授权

US08975067B2 Self-contained sterilization indicators including a neutralizer for residual oxidizing sterilant 有权
标题翻译：独立灭菌指示剂，包括残留氧化灭菌剂的中和剂
公开(公告)号：US08975067B2
公开(公告)日：2015-03-10
申请号：US13995524
申请日：2011-12-20
申请人： William E. Foltz , Francois Ahimou , G. Marco Bommarito , Robert A. Asmus , Louis C. Haddad , Tushar A. Kshirsagar
发明人： William E. Foltz , Francois Ahimou , G. Marco Bommarito , Robert A. Asmus , Louis C. Haddad , Tushar A. Kshirsagar
IPC分类号： C12M3/00
CPC分类号： C12Q1/22 , C12Q1/25 , G01N21/78 , G01N31/226 , G01N33/573 , G01N2021/7786 , G01N2458/00
摘要： Sterilization indicators that include a neutralizer, such indicators useful for testing the effectiveness of a sterilization procedure by measuring the activity of an active enzyme whose activity is correlated with the survival of microorganisms.
摘要翻译：包括中和剂的消毒指示剂，这些指标可用于通过测量活性与微生物存活相关的活性酶的活性来测试灭菌程序的有效性。

6. 发明申请

US20120164056A1 GENERATION OF STERILANT GASSES AND USES THEREOF 审中-公开
标题翻译：无菌大便的产生及其用途
公开(公告)号：US20120164056A1
公开(公告)日：2012-06-28
申请号：US13381219
申请日：2010-06-28
申请人： Louis C. Haddad , William E. Foltz , Greggory S. Bennett , Robert A. Asmus
发明人： Louis C. Haddad , William E. Foltz , Greggory S. Bennett , Robert A. Asmus
IPC分类号： A61L2/20 , C09K3/00 , C01B21/36
CPC分类号： A61L2/20 , A61L2/202 , A61L2/206 , A61L2/208 , A61L2/24 , A61L2202/11 , A61L2202/122 , A61L2202/14 , A61L2202/24 , C01B11/022 , C01B21/20 , C01B21/36
摘要： The disclosure provides processes and systems for sterilizing an object using a sterilant gas. In some embodiments, the sterilant gas is produced by the thermal decomposition of a salt. Compositions to generate sterilant gasses are also disclosed.
摘要翻译：本公开提供了使用灭菌气体对物体进行灭菌的过程和系统。在一些实施方案中，消毒剂气体是通过盐的热分解产生的。还公开了产生灭菌气体的组合物。

7. 发明申请

US20110110869A1 STABLE HYDROALCOHOLIC COMPOSITIONS 审中-公开
标题翻译：稳定的水溶性组合物
公开(公告)号：US20110110869A1
公开(公告)日：2011-05-12
申请号：US13006583
申请日：2011-01-14
申请人： Matthew T. Scholz , Robert A. Asmus , Jill R. Charpentier
发明人： Matthew T. Scholz , Robert A. Asmus , Jill R. Charpentier
IPC分类号： A61K9/12
CPC分类号： A61K8/34 , A61K8/342 , A61K8/37 , A61K8/39 , A61K8/416 , A61K8/604 , A61K8/86 , A61Q17/005 , A61Q19/00 , Y10S514/846 , Y10S514/873 , Y10S514/944 , Y10S514/945 , Y10S514/946 , Y10S514/975
摘要： Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.
摘要翻译：公开了包含低级醇和水的组合物，其重量比为约35:65至100:0，至少0.5重量％至8.0重量％的包含至少两种乳化剂的增稠剂体系，每种乳化剂存在于至少0.05 重量％，并且其中每种乳化剂由至少一个疏水基团和至少一个亲水基团组成。组合物可用作术前洗刷替代物，洗剂或其他手制剂。

8. 发明申请

US20100331411A1 FOAMABLE ALCOHOL COMPOSITIONS, SYSTEMS AND METHODS OF USE 审中-公开
公开(公告)号：US20100331411A1
公开(公告)日：2010-12-30
申请号：US12878786
申请日：2010-09-09
申请人： Robert A. Asmus
发明人： Robert A. Asmus
IPC分类号： A01N31/02 , A01N47/44 , A01N31/08 , A01N31/16 , A01N37/36 , A01P1/00 , B67D7/76
CPC分类号： A61K8/894 , A61K8/34 , A61K8/731 , A61K8/86 , A61Q17/005 , C11D1/82 , C11D3/0094 , C11D3/2006 , C11D3/201 , C11D3/225 , C11D3/3707 , C11D3/48
摘要： A composition, systems for dispensing the composition and methods for the use of the composition are described. The composition comprises: (A) Monohydric alcohol in an amount sufficient to provide antimicrobial activity; (B) Surfactant comprising a dimethicone surfactant; and (C) Builder, the builder in an amount sufficient to provide stability or to improve the stability of a foam formed from the composition.

9. 发明授权

US06458341B1 Devices with coatings containing chlorhexidine gluconate, compositions and methods 失效
标题翻译：含有葡萄糖酸洗必太的涂层的装置，组合物和方法
公开(公告)号：US06458341B1
公开(公告)日：2002-10-01
申请号：US09089872
申请日：1998-06-04
申请人： Sharon M. Rozzi , Robert A. Asmus , Brian R. Morrison
发明人： Sharon M. Rozzi , Robert A. Asmus , Brian R. Morrison
IPC分类号： A61K722
CPC分类号： A61K8/345 , A61K8/43 , A61Q11/00 , Y10T428/2938
摘要： Devices, coating compositions and methods for making such compositions are provided, wherein the coatings deliver chlorhexidine gluconate from a stable non-aqueous system.
摘要翻译：提供了用于制备这种组合物的装置，涂料组合物和方法，其中所述涂层从稳定的非水系统递送氯己定葡萄糖酸氯己定。

10. 发明授权

US09278155B2 Adhesive compositions, articles incorporating same and methods of manufacture 有权
标题翻译：粘合剂组合物，包含其的制品和制造方法
公开(公告)号：US09278155B2
公开(公告)日：2016-03-08
申请号：US10456811
申请日：2003-06-05
申请人： Robert A. Asmus , Beatrice C. Etzold , Joy A. Packard
发明人： Robert A. Asmus , Beatrice C. Etzold , Joy A. Packard
IPC分类号： A61F13/02 , A61L15/58 , C09J133/24 , C08K5/053 , C08L1/00 , C08L5/00
CPC分类号： A61L15/58 , C08K5/053 , C08L1/00 , C08L5/00 , C08L2666/26 , C09J133/24 , C08L39/04
摘要： A hydrophilic, pressure-sensitive adhesive composition comprising crosslinked poly(N-vinyl lactam), a swelling agent, and a modifying polymer in an amount sufficient to form a cohesive pressure-sensitive adhesive composition is provided. The composition is useful as a medical secural of percutaneous devices. The composition is also useful as a drug delivery device to deliver antimicrobial agents, pharmaceuticals or other active ingredients to or through skin. A method of preparation of the composition is also disclosed.
摘要翻译：提供一种亲水性压敏粘合剂组合物，其包含交联的聚（N-乙烯基内酰胺），溶胀剂和改进聚合物，其量足以形成内聚压敏粘合剂组合物。该组合物可用作经皮装置的医学证实。该组合物还可用作药物递送装置，以将抗微生物剂，药物或其它活性成分递送至皮肤或通过皮肤。还公开了组合物的制备方法。

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