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1. 发明申请

US20090224164A1 SCINTILLATION DETECTOR FOR POSITRON EMISSION TOMOGRAPHY 有权
标题翻译：用于放射性血管造影的扫描检测器
公开(公告)号：US20090224164A1
公开(公告)日：2009-09-10
申请号：US12259270
申请日：2008-10-27
申请人： Thomas Lewellen , Robert Miyaoka , Abdelmounaime Faouzi Zerrouk
发明人： Thomas Lewellen , Robert Miyaoka , Abdelmounaime Faouzi Zerrouk
IPC分类号： G01T1/20
CPC分类号： G01T1/1642
摘要： The invention disclosed herein is directed to scintillation detectors capable of detecting the position or depth of gamma photon interactions occurring within a scintillator, thereby improving the resolution of ring based positron emission tomography (PET) imaging systems. In one embodiment, the invention is directed to a scintillation detector that comprises at least one pair of side-by-side conjunct scintillation crystal bars having a shared interface between, and a solid-state semiconductor photodetector optically coupled to each output window of each individual scintillation crystal bar. The solid-state semiconductor photodetector includes an array of discrete sensitive areas disposed across a top surface of a common substrate, wherein each sensitive area contains an array of discrete micro-pixelated avalanche photodiodes, and wherein the output window of each scintillation crystal bar is optically coupled to each respective sensitive area in a one-on-one relationship.
摘要翻译：本文公开的本发明涉及能够检测闪烁体内发生的γ光子相互作用的位置或深度的闪烁检测器，从而提高基于环的正电子发射断层摄影（PET）成像系统的分辨率。在一个实施例中，本发明涉及一种闪烁检测器，其包括至少一对并排结合闪烁晶体棒，其具有与每个个体的每个输出窗口光耦合的固态半导体光电检测器之间的共享接口闪烁晶体棒。固体半导体光电检测器包括跨越公共基底的顶表面设置的离散敏感区域的阵列，其中每个敏感区域包含离散的微像素化雪崩光电二极管的阵列，并且其中每个闪烁晶体棒的输出窗口是光学的以一对一的关系耦合到每个相应的敏感区域。

2. 发明授权

US07956331B2 Scintillation detector for positron emission tomography 有权
标题翻译：用于正电子发射断层扫描的闪烁检测器
公开(公告)号：US07956331B2
公开(公告)日：2011-06-07
申请号：US12259270
申请日：2008-10-27
申请人： Thomas Lewellen , Robert Miyaoka , Abdelmounaime Faouzi Zerrouk
发明人： Thomas Lewellen , Robert Miyaoka , Abdelmounaime Faouzi Zerrouk
IPC分类号： G01T1/20
CPC分类号： G01T1/1642
摘要： The invention disclosed herein is directed to scintillation detectors capable of detecting the position or depth of gamma photon interactions occurring within a scintillator, thereby improving the resolution of ring based positron emission tomography (PET) imaging systems. In one embodiment, the invention is directed to a scintillation detector that comprises at least one pair of side-by-side conjunct scintillation crystal bars having a shared interface between, and a solid-state semiconductor photodetector optically coupled to each output window of each individual scintillation crystal bar. The solid-state semiconductor photodetector includes an array of discrete sensitive areas disposed across a top surface of a common substrate, wherein each sensitive area contains an array of discrete micro-pixelated avalanche photodiodes, and wherein the output window of each scintillation crystal bar is optically coupled to each respective sensitive area in a one-on-one relationship.
摘要翻译：本文公开的本发明涉及能够检测闪烁体内发生的γ光子相互作用的位置或深度的闪烁检测器，从而提高基于环的正电子发射断层摄影（PET）成像系统的分辨率。在一个实施例中，本发明涉及一种闪烁检测器，其包括至少一对并排结合闪烁晶体棒，其具有与每个个体的每个输出窗口光耦合的固态半导体光电检测器之间的共享接口闪烁晶体棒。固体半导体光电检测器包括跨越公共基底的顶表面设置的离散敏感区域的阵列，其中每个敏感区域包含离散的微像素化雪崩光电二极管的阵列，并且其中每个闪烁晶体棒的输出窗口是光学的以一对一的关系耦合到每个相应的敏感区域。

3. 发明申请

US20070167716A1 Method for enhancing the accuracy of PET/CT images 有权
标题翻译：提高PET / CT图像精度的方法
公开(公告)号：US20070167716A1
公开(公告)日：2007-07-19
申请号：US11595389
申请日：2006-11-10
申请人： Paul Kinahan , Adam Alessio , Thomas Lewellen , Hubert Vesselle
发明人： Paul Kinahan , Adam Alessio , Thomas Lewellen , Hubert Vesselle
IPC分类号： A61B5/05
CPC分类号： A61B6/405 , A61B6/032 , A61B6/4014 , A61B6/482
摘要： A method is disclosed for obtaining linear attenuation coefficients for interpreting a PET scan of a region. The method is suitable for use when high molecular weight materials are present in the region, such as contrast agents or metal objects. The method includes obtaining first and second x-ray CT data sets of the region of interest at two different energies or voltage potentials and differencing corresponding CT numbers. The difference values are used to distinguish portions of the region that are bone from portions of the region that are contrast agent or other high molecular weight material. The obtained CT data set is then used to obtain an attenuation coefficient map of the region at the PET energy of 511 keV, for example, using a linear scaling factor suited to the particular identified material. Difference values at or near zero may be used to identify soft tissue portions of the region.
摘要翻译：公开了一种用于获得用于解释区域的PET扫描的线性衰减系数的方法。当该区域中存在高分子量材料时，如造影剂或金属物体，该方法适合使用。该方法包括以两个不同的能量或电压电位获得感兴趣区域的第一和第二X射线CT数据集，并差分相应的CT数。差值用于区分作为造影剂或其它高分子量材料的区域的部分作为骨的部分。然后使用所获得的CT数据集来获得例如在511keV的PET能量下的区域的衰减系数图，例如使用适合于特定识别材料的线性缩放因子。在零附近或接近零的差值可用于识别该区域的软组织部分。

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